scholarly journals ANALISIS KADAR ALBUMIN SERUM DENGAN RASIO DE RITIS PADA PENDERITA HEPATITIS B

Author(s):  
AT. Lopa ◽  
B. Rusli ◽  
M. Arif ◽  
Hardjoeno Hardjoeno

Hepatitis is a inflammation process which may present in an acute or chronic phase. A decrease of serum albumin level may befound in liver disease. Ratio de Ritis in mild hepatitis is < 1 while in alcoholic hepatitis is >1. To analyze serum albumin level withratio de Ritis in hepatitis B patients. A cross sectional study was carried out comprising 46 subjects from October 2005 to August 2006measuring albumin level SGOT and SGPT levels using Lyasis autoanalyzer. Thirty eight males and eight females, the level of serumalbumin decreased with an average of albumin level 2.98 gr/dL (p<0.05). Twenty two subjects showed a ratio de Ritis ≤ 1 with theaverage albumin level 3.00 gr/dL and 24 subjects were included in group ratio de Ritis > 1 with average albumin level 2.96 gr/dL(p value = 0.658). There was a decrease of serum albumin level in hepatitis B patient but no significant difference between decrease ofserum albumin level with ratio of de Ritis ≤ 1 and ratio of de Ritis >1.

2021 ◽  
Vol 8 (04) ◽  
pp. 204-207
Author(s):  
Shreyansh Talera ◽  
Saurabh Singhal ◽  
Nishant Wadhera ◽  
Mayank Arora ◽  
Ravi Pratap

BACKGROUND WHO has declared Coronavirus disease 2019 (Covid-19) as a pandemic. Covid-19 leads to sickness and death. Human serum albumin (HSA) is the most common circulating protein in the body having oncotic as well as non-oncotic properties. The role of albumin in death among Covid-19 subjects, especially in this part of the country has not been frequently reported. The aim of the study was to analyse the role of serum albumin level as prognostic marker for Covid-19 positive patients. METHODS The present study was conducted in the department of Medicine at Chhatrapati Shivaji Subharti Hospital, Subharti Medical College, Meerut, UP. The study comprised of 100 subjects who were Covid positive from May 2020 to July 2020. A detailed explanation was given to all the participating respondents regarding the study and their contribution to it. Covid-19 was diagnosed on the basis of the WHO interim guidelines. A questionnaire was prepared to collect the patients’ demographic profile. Patients date of admission and discharge was recorded along with the outcome i.e., whether patient expired or survived. Patients’ diagnosis was identified along with the comorbidity (if present). Laboratory investigations comprised of CBC and serum albumin detection. Data so collected was tabulated in an excel sheet, under the guidance of statistician. Collected data was analysed using Statistical Package for the Social Sciences (SPSS) software version 24 and the tests used were t test and Fisher’s exact test and the level of significance was set at p < 0.05. RESULTS The study comprised of 100 subjects, out of which 45 were males and 55 were females. The overall mean age of the study subjects was 37.52 years. In our study, mortality was 35.29 %, 9.33 % and 85.7 % of the subjects having Covid-19+ type 2 diabetes (T2DM), only Covid-19 and Covid-19+ hypertension respectively with statistically significant difference as p < 0.05. Albumin level was significantly lower in expired patients (2.99) as compared to survivors (3.85) as p < 0.05. Hospital stay was also higher in expired patients. CONCLUSIONS Covid-19 patients had low serum albumin levels and that might play a role in the survival of patient. KEYWORDS Covid-19, Mortality, Albumin


2019 ◽  
Vol 26 (03) ◽  
Author(s):  
Nadia Ijaz ◽  
Tazeen Nazar ◽  
Bilal Aziz

Objectives: To determine the correlation between serum albumin levels and the grades of esophageal varices in patients of liver cirrhosis due to hepatitis B and C. Study Design: Cross-sectional descriptive study. Place and Duration of Study: Unit I, Department of Medicine, Allied Hospital, Faisalabad from 29th June, 2014 to 28th December, 2014. Methodology: 95 patients of either sex between 20-70 years of age, with the diagnosis of liver cirrhosis due to hepatitis B and C were selected using non - probability consecutive sampling. The presence of esophageal varices was confirmed by endoscopy. Results: Out of a total of 95 patients, 59 (62.11%) were between the age group of 20-50 years while 36 (37.89%) were between 51-70 years of age. Mean+SD was calculated as 48.37+11.75 years. Gender distribution showed that 51 (53.68%) patients were males and 44 (46.32%) were females. Correlation between serum albumin level and the grade of esophageal varices in patients of liver cirrhosis due to hepatitis B & C showed that out of 26 cases with serum albumin level <2.8, 10 had Grade I and 16 had Grade II while out of 69 cases with ≥2.8 serum albumin level, 40 had grade I and 29 had grade II EV. r value was recorded to be -0.697 whereas p-value was calculated as 0.000. Conclusion: There is a significant negative correlation between serum albumin level and grade of esophageal varices in patients of liver cirrhosis due to hepatitis B and C.


Author(s):  
Amir Emami ◽  
Fatemeh Javanmardi ◽  
Ali Akbari ◽  
Babak Shirazi Yeganeh ◽  
Tahereh Rezaei ◽  
...  

Background: Identifying effective biomarkers plays a critical role on screening; rapid diagnosis; proper managements and therapeutic options, which is helpful in preventing serious complications. The present study aimed to compare the liver laboratory tests between alive and dead hospitalized cases for prediction and proper management of the patients. Methods: This retrospective, cross sectional study consists of all deceased patients admitted in one center in Shiraz, Iran during 19 Feb 2020 to 22 Aug 2021. For further comparison, we selected a 1:2 ratios alive group randomly. Results: Overall, 875 hospitalized cases died due to COVID-19. We selected 1750 alive group randomly. The median age was significantly higher in died group (65.96 vs 51.20). Regarding the laboratory findings during the hospitalization ALT, AST, Bili.D were significantly higher in non-survivors than survivors but Albumin was less in deceased patients. It was revealed elevated levels of Albumin, AST, Bili.T and Bili.D were associated with increasing the risk of in hospital death. Moreover, the predictive effect of ALP and Bili.D had significantly more than others with high sensitivity and specify. Conclusion: We found patients with COVID-19 have reduced serum albumin level, and increase ALT and AST. The current results revealed abnormal liver chemistries is associated with poor outcome, which highlighted the importance of monitoring these patients more carefully and should be given more caution.


2021 ◽  
Author(s):  
Rana Kurdi ◽  
Hanan Abdul Rahim ◽  
Ghadir Al-Jayyousi ◽  
Manar Yaseen ◽  
Aetefeh Ali ◽  
...  

Background: Electronic cigarette (e-cigarette) use is becoming popular worldwide especially among youth. Research reported that university students have poor knowledge and misconceptions about the health risks of e-cigarettes, which may lead students to use them even in populations where prevalence of cigarette smoking is relatively low. At this age, the influence of peers is also significant. In this study, we assessed the prevalence of e-cigarette use among university students as well as their knowledge and attitudes towards e-cigarettes. Methodology: We conducted a cross-sectional study among Qatar University students using a self-administered online questionnaire. Descriptive univariate analysis of all variables was conducted as well as a bivariate analysis to check the association of e-cigarette use with selected variables. A binary logistic regression was conducted to assess predictors of e-cigarette use. Results: The prevalence of e-cigarette use among students was found to be 14% where 32% of them were daily users. Approximately 42% of the participants agreed that ‘e-cigarettes are less harmful to health compared to traditional cigarettes, and 45.7% of them agreed that ‘e-cigarettes can prevent smoking traditional cigarettes. The prevalence of e-cigarettes use was 16.2% among males and 12.8% among females, which showed no significant difference between the two genders. Females were more likely to use e-cigarettes because they “don’t smell” (P-value=0.023). The study showed a significant association between e-cigarette use and knowledge items (P-value < 0.05) and having a smoker among siblings or friends. At the multivariate analysis level, only the friends’ effect remained significant after controlling for the other variables (OR= 7.3, P-value=0.000). Conclusion: Our research found that university students have inadequate knowledge and misconceptions in regards to e-cigarettes use, especially among users. Effective smoking prevention policy and educational interventions are needed to enhance awareness among university students about the health effects associated with e-cigarettes use.


2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Rafika Oktova ◽  
Desmiwarti Desmiwarti ◽  
Arni Amir

AbstrakDepo Medroksiprogesteron Asetat dan Implant Levonorgestrel merupakan kontrasepsi hormonal progestin sintetik yang memiliki efek samping yaitu peningkatan berat badan dan mempengaruhi metabolisme lipid. Tujuan penelitian ini adalah untuk mengetahui perbedaan profil lipid pada akseptor Depo Medroksiprogesteron Asetat dengan Implant Levonorgestrel. Ini adalah studi observasional dengan desain cross sectional comparative. Penelitian dilakukan di laboratorium Bagian Biokimia Fakultas Universitas Andalas dari Maret sampai Mei 2014. Subjek penelitian terdiri dari dua kelompok, masing-masing 20 subjek. Pemeriksaan dengan metode enzimatis kolorimetri yaitu GPO-PAP untuk trigliserida, dan CHOD-PAP untuk kolesterol total, HDL dan LDL. Data dianalisis menggunakan uji t dengan nilai p<0.05 dianggap bermakna secara statistik. Rerata kadar LDL pada Depo Medroksiprogesteron Asetat lebih tinggi (95,51 ± 20,47) mg/dl daripada Implant Levonorgestrel (79,35 ± 12,55) mg/dl dengan nilai p<0,05 artinya terdapat perbedaan yang bermakna sedangkan kadar trigliserida, kolesterol total dan HDL tidak bermakna. Kesimpulan penelitian in adalah terdapat perbedaan yang bermakna rerata kadar LDL pada Depo MedroksiprogesteronAsetat dan Implant Levonorgestrel, sedangkan kadar trigliserida, kolesterol total dan HDL tidak bermakna. Secara klinis profil lipid pada kedua kelompok dalam keadaan normal.Kata kunci: profil lipid, depo medroksiprogesteron asetat, implant levonorgestrelAbstractDepo Medroxyprogesterone Acetate and Levonorgestrel Implants are synthetic progestine hormonal contraceptives that have side effect in body weight and lipid metabolism. The objective of this study was to determine the differences of lipid profile between acceptors Depo Medroxyprogesterone Acetate and Levonorgestrel Implants. This was a comparative cross sectional study. The study was done at laboratory of Biochemistry Departement in Medical Faculty of Andalas University from March until May 2014. The subjects were consisted of two groups, each group had 20 subjects. The examination used an enzymatic colorimetric method GPO-PAP for trygliserides and CHOD-PAP for total cholesterol, HDL and LDL. Data was analyzed using analysis of t-test with p<0.05 was considered to be significantly different. LDL levels average in Depo Medroxyprogesterone Acetate was (95,51 ± 20,47) mg/dl and Levonorgestrel Implants was (79,35 ± 12,55) mg/dl with p-value, it means there is a significantly difference, but levels of trygliserides, total cholesterol and HDL means there is no significantly difference. This research concluded that there is a significant difference on average levels of LDL in the Depo Medroxyprogesterone Acetate and Levonorgestrel Implants but levels of trygliserides, total cholesterol and HDL there is no significantly difference. The clinically lipid profile in the two groups is in normal range.Keywords: lipid profile, depo medroxyprogesterone acetate and levonorgestrel implants


Thrita ◽  
2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Fatemeh Mousavi ◽  
Parisa Shojaei ◽  
Azadeh Nazemi ◽  
Atefe Dadashi

Objectives: This research has been conducted to study antibiotic self-medication, prevalence, and reasons. Methods: A questionnaire containing 30 comprehensive questions in terms of the experience of antibiotic self-medication was prepared. In this cross-sectional study, data were analyzed using analytical statistics bases on chi-square and logistic regression. Results: The results showed that 61.3% of the participants were self-antibiotic users. There was a significant difference only between gender and self-medication such that self-medication in males was more than females (P value = 0.027). Conclusions: Self-medication of antibiotics is almost high and requires more information about the side effects of these drugs in order to promote rational and physically prescribed use.


2021 ◽  
Vol 71 (5) ◽  
pp. 1582-84
Author(s):  
Hassam Anjum Mir ◽  
Mubashir Sharif ◽  
Ali Asif ◽  
Maleeha Shamim ◽  
Maaz Qureshi ◽  
...  

Objective: To determine if the traditional chewing stick Miswak was as effective in cleaning teeth as Toothbrush. Study Design: Cross sectional study. Place and Duration of Study: Armed Forces Institute of Dentistry, Rawalpindi, from Aug 2020 to Jan 2021. Methodology: A total of 300 subjects were included which were divided in two groups on the basis of whether they used miswak or toothbrush as a cleaning aid. Group A was toothbrush users and group B was Miswak user. Plaque Index was used to determine the cleanliness of teeth. The scores were recorded and data analyzed using SPSS-23. Results: The means and standard deviations of Plaque Index score for group A and B were 0.96 ± 0.58 and 0.98 ± 0.56 respectively. The comparison of Plaque Index score for both groups was insignificant with the p-value of 0.083. Conclusion: Within the limitations of this study, it is concluded that, no significant difference was found in the effectiveness of traditional miswak and tooth brush. It is recommended that if the technique of teeth cleaning is good then any of the abovementioned means of teeth cleaning can be used.


Author(s):  
Prakash B. ◽  
Pradeep T. S. ◽  
Praveen Kulkarni ◽  
M. R. Narayana Murthy

Background: One of the features of modern life is ever increasing stress. Stress is an epidemic in the 21st century that commonly affects all of us on a daily basis. Adolescence can be a stressful time as this age group people are dealing with the challenges of puberty, changing expectations and coping with new feelings. Coping is the process of managing demands (external or internal) that are appraised as taxing or exceeding the resources of the person. Coping consists of efforts, both action-oriented and intrapsychic. The relationship between coping and a stressful event represents a dynamic process. With this background study was conducted to assess the coping ability of tribal, rural and urban school children of Mysuru District. Methods: A community based cross-sectional study conducted in Tribal, rural and urban Mysuru.A Pre tested semi-structured proforma which included general profile and socio-demographic profile of student was used. Information about coping skills was collected through Tobin Coping Strategies Inventory 32 item scale. Statistical analysis: Descriptive statistics like mean and standard deviation were applied. Anova test for comparison of means between three groups. Independent t test was applied for comparison between two groups. The association was expressed statistically significant at p-value less than 0.05. Results: In regards to problem solving, cognitive restructuring, expressing emotions, social contact, wishful thinking, social withdrawal, self-criticism there was a significant difference among 3 groups with p-value <0.05, with regards to problem focused engagement and emotion focused engagement there was a significant difference among 3 groups with p-value< 0.05 with tribal high school participants having higher scores and with regards to engagement there was a significant difference among 3 groups with p-value <0.05 with tribal high school participants having higher scores.Conclusions: The present study was a community based cross sectional study conducted among tribal, rural and urban high school students of Mysuru district aged 14-16 years which revealed tribal school participants had better coping strategy next to urban. Males differed from females with respect to their coping strategies especially in rural and urban participants.


2017 ◽  
Vol 4 (6) ◽  
pp. 2205
Author(s):  
Madhivanan S. ◽  
Harikrishnan E. ◽  
Kumarasamy K.

Background: Blood pressure measurements in childhood are an important clinical examination. Present study was done to evaluate the normal range of blood pressure (BP) in children aged 6-12 years and to find its relationship with regard to age, sex, height and weight criteria and comparing the values with the available standards.Methods: This prospective cross-sectional study was done in primary and middle schools of Chennai from January 2016 to May 2017. Three readings of blood pressure were recorded for each subject and were correlated with age, gender, socioeconomic status and anthropometry. Data was analysed on SPSS 20.0. P value of <0.05 was considered significantResults: A total of 2002 children (1026 boys, 976 girls) of age between 6-12 years were examined over 18 months. There was an upward trend in both systolic (r = 0.437, P<0.001) and diastolic BP (r = 0.386, P <0.001) with age. There was no statistically significant difference in mean systolic and diastolic BP with gender (P = 0.10), weight (P = 0.10) and height (P = 0.10). There was a statistically significant difference between the mean systolic and diastolic BP between low and high socio-economic groups (P <0.0001). The proportion of children with hypertension was 9.54% with a slight female preponderance.Conclusions: Blood pressure measurement in children is pivotal in clinical examination. It shows a linear relationship with age and varies across socio-economic status. Periodic recording of BP would enable identify hypertension at an early age.


2016 ◽  
Vol 17 (6) ◽  
pp. 440-444 ◽  
Author(s):  
Abdullah G Amran ◽  
Noor Al-Huda M Al-Rafik

ABSTRACT Introduction Epidemiological data on gingivitis in children are important for understanding the natural course of the disease, identifying its risk factors, and predicting its time trends. The objective of this study was to evaluate the prevalence and severity of gingivitis among 6- and 12-year-old school children in Dhamar city, Yemen. Materials and methods A total of 663 children (310 children of 6 years old and 353 children of 12 years old) were examined from 10 public primary schools. Gingival health status was assessed using the plaque index (PI), calculus index (CI), and gingival index (GI) on the six Ramfjord teeth. The latter index was used to categorize gingivitis severity at the subject level. Data were analyzed using independent t-test, chi-squared test, and Spearman's correlation. A p-value of < 0.05 was considered significant. Results Both age groups had high mean of PI and GI with nonsignificant difference. The 12-year-old children had calculus deposits much higher than the 6-year-old group with significant difference. There was a significant correlation between age and gender of the whole sample with CI [(odds ratio, OR = 1.65, p = 0.003) and (OR = 0.74, p = 0.05) respectively]. Most of the participants presented with gingival inflammation, which was less in 12-year-old females. Conclusion Poor oral hygiene and mild gingivitis were highly prevalent among Yemeni school children. Clinical significance The early assessment and intervention of gingivitis and periodontitis will minimize the chance of tooth loss. It has been reported that marginal gingivitis begins early in childhood, increases in prevalence and severity at puberty, and then subsides slightly to the remainder of the second decade of life. How to cite this article Amran AG, Alhajj MN, Al-Rafik NA-HM. Evaluation of Gingival Health Status among 6- and 12-years-old Children in Dhamar City, Yemen: A Cross-sectional Study. J Contemp Dent Pract 2016;17(6):440-444.


Sign in / Sign up

Export Citation Format

Share Document