scholarly journals Dengue infections during pregnancy: case series from a tertiary care hospital in Sri Lanka

2010 ◽  
Vol 4 (11) ◽  
pp. 767-775 ◽  
Author(s):  
Sampath Kariyawasam ◽  
Hemantha Senanayake
Keyword(s):  
Sri Lanka ◽  
Pregnant Women ◽  
Clinical Laboratory ◽  
Multiorgan Failure ◽  
Demographic Data ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Case Series ◽  
Care Hospital ◽  
In Pregnancy

Introduction: Dengue is the most important mosquito-borne disease in Sri Lanka, leading to more than 340 deaths during the last outbreak (≈35,000 reported cases) starting in mid April 2009. The predominant dengue virus serotypes during the last few years have been DENV-2 and DENV-3. Dengue infection in pregnancy carries the risk of hemorrhage for both the mother and the newborn. Other risks include premature birth, fetal death, and vertical transmission. We report clinical and laboratory findings and outcomes in pregnant women hospitalized with dengue infection during pregnancy. Methodology: Clinical, laboratory, maternal/fetal outcomes and demographic data were collected from patients with confirmed dengue infections during pregnancy treated at De Soysa Maternity Hospital, Sri Lanka from 1 May 2009 to 31 December 2009. Results:  Fifteen seropositive dengue infected pregnant women were diagnosed in the period. Multiorgan failure leading to intrauterine fetal and maternal death occurred in one case of dengue hemorrhagic fever (DHF) IV. One patient with DHF III had a miscarriage at the 24th week of gestation. Perinatal outcomes of the other cases were satisfactory. One woman developed dengue myocarditis but recovered with supportive treatments. No cases of perinatal transmission to the neonate occurred. Conclusion: Dengue in pregnancy requires early diagnosis and treatment. A high index of clinical suspicion is essential in any pregnant woman with fever during epidemic. Further studies are mandatory as evidence-based data in the management of dengue specific for pregnancy are sparse.

scholarly journals Outcome of Dengue infection in pregnancy at a tertiary care hospital in India

2020 ◽  
Vol 9 (3) ◽  
pp. 970
Author(s):  
Naimah Raza ◽  
Nitin P. Dhungat
Keyword(s):  
Clinical Laboratory ◽  
Tertiary Care Hospital ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Perinatal Outcomes ◽  
Severe Dengue ◽  
Care Hospital ◽  
Laboratory Findings ◽  
Bleeding Manifestation ◽  
In Pregnancy

Background: Dengue is one of the most important mosquito-borne diseases in India. This study was done to study the course of dengue infection in pregnant women, its effects, foeto-maternal outcome, and associated complications.Methods: Clinical, laboratory findings, and maternal/foetal outcome were collected from patients with confirmed dengue infections in pregnancy treated at a tertiary care hospital in India, during a 6-month period.Results: A total 12 seropositive cases of dengue infection in pregnancy were diagnosed during the study period. Thrombocytopenia coupled with rising haematocrit were seen in all cases. Prophylactic platelet transfusion was not necessary in any of the cases without bleeding manifestation. Three patients developed severe dengue with some complication requiring extra measures, including a case of dengue encephalitis which responded to supportive treatment. One case of intra-uterine foetal demise and multi-organ failure leading to maternal death was seen. Perinatal outcomes of the other cases were satisfactory.Conclusions: Dengue in pregnancy requires early diagnosis and treatment. A high index of clinical suspicion is essential in any pregnant woman with fever, especially in endemic areas. Further studies are necessary as evidence-based data in the management of dengue in pregnancy is inadequate.

scholarly journals Dengue infection in pregnancy and outcome in a tertiary care centre

2018 ◽  
Vol 7 (12) ◽  
pp. 5051
Author(s):  
Veena L. ◽  
Srinivas Srinivas ◽  
Aruna Aruna
Keyword(s):  
Pregnant Women ◽  
Multiorgan Failure ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Fluid Management ◽  
Close Monitoring ◽  
Tertiary Care Centre ◽  
Maternal Complications ◽  
Mortality And Morbidity ◽  
In Pregnancy

Background: Dengue is a mosquito borne viral infection with significant disease burden across the country. With the recent resurgence of the disease, increasing number of people are affected including pregnant women. Risk of exposure is 1% in a given pregnancy in highly endemic areas. The objective is to study the morbidity and mortality profile of dengue in pregnancy on mother and neonate.Methods: It is a time bound retrospective study conducted on 25 pregnant women with positive dengue serology in Department of Obstetrics and Gynecology BMCRI Bangalore India between May to October 2016.Results: 25 seropositive dengue infected pregnant women were diagnosed in the period. Multiorgan failure leading to intrauterine fetal and maternal death occurred in one case of dengue shock syndrome at 28 weeks. Perinatal outcomes of the other cases were satisfactory. No cases of perinatal transmission to the neonate occurred.Conclusions: Pregnancies complicated by dengue infection needs close monitoring in a tertiary care for potential fetal and maternal complications. Early detection of the critical phase, with judicious fluid management can decrease the mortality and morbidity associated with dengue infection. 

scholarly journals Knowledge and Practices of Pregnant Women regarding Oral Health in A Tertiary Care Hospital in Nepal

2019 ◽  
Vol 57 (217) ◽  
Author(s):  
Neha Gupta ◽  
Manisha Chhetry
Keyword(s):  
Oral Health ◽  
Pregnant Women ◽  
Dental Care ◽  
Dental Health ◽  
Care Center ◽  
Tertiary Care ◽  
Care Hospital ◽  
Perinatal Complications ◽  
Institutional Review ◽  
In Pregnancy

Introduction: Poor dental hygiene has been associated with various perinatal complications in studiesdone worldwide but few studies in Nepal have explored the knowledge of pregnant ladies regardingdental hygiene. The aim of the study was to know the knowledge and practices of pregnant womenregarding oral health in a tertiary care center in Nepal. Methods: A qualitative study was carried out in Nobel Medical College and Teaching Hospital fromJanuary 15, 2018 to June 15, 2018 after approval from the Institutional Review Committee of NobelMedical College. Convenience sampling was done. Fifty pregnant women admitted in antenatalward were interviewed regarding their knowledge of dental care in pregnancy, the common dentalproblems they faced and the treatment taken. A predesigned proforma was used and results wereanalyzed using SPSS version 17. Results: Twenty two (44%) patients reported dental problems during pregnancy. Bleeding gumswas seen in 7 (14%) and toothache in 7 (14%) were commonly reported dental problems. Forty seven(94%) patients acknowledged that routine dental care was needed for health, only 6 (12%) wereaware that poor dental health could affect baby weight. Oral health not seen as priority in 24 (48%)was the main barrier to seeking dental care in pregnancy followed by costs of treatment in 18 (36%)and safety concerns in pregnancy in 8 (16%) cases. Conclusions: Though dental problems were a common occurrence in pregnancy, utilization ofservices was low for the same. The participants reported significant barriers to obtaining dental careincluding lack of knowledge about the importance of maternal oral health and the treatment costs.

scholarly journals Susceptibility for varicella and factors associated with immunity among pregnant women in a tertiary care hospital in Sri Lanka- a cross-sectional study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ishara P. Premathilake ◽  
Praveena Aluthbaduge ◽  
Channa P. Senanayake ◽  
Renuka Jayalatharachchi ◽  
Sirithilak Gamage ◽  
...  
Keyword(s):  
Sri Lanka ◽  
Pregnant Women ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated

scholarly journals DILEMMAS IN MANAGEMENT OF PREGNANT PATIENTS WITH MECHANICAL PROSTHETIC VALVES IN RURALAND SEMI-URBAN NORTH INDIAN POPULATION AT A TERTIARY CARE INSTITUTION.

2020 ◽  
pp. 44-45
Author(s):  
Amrit Gupta ◽  
Varuna Varma ◽  
Indrani Ghosh ◽  
Nirmal Kumar Gupta ◽  
Neeraj Kumar
Keyword(s):  
Pregnant Women ◽  
Heart Valves ◽  
Economic Status ◽  
Tertiary Care ◽  
Multiple Pregnancy ◽  
Mechanical Heart Valves ◽  
Successful Outcome ◽  
Congenital Defects ◽  
Care Hospital ◽  
In Pregnancy

Pregnancy is a prothrombotic stage, and in women with mechanical heart valves, anticoagulation is a challenge to attain an optimal outcome in mother and fetus. The use of combinations coumadin derivatives and various heparins is still in inconclusive stage due to various socioeconomic and demographic situation. In developing countries due to the cost of surgery, and compliance with lifelong anticoagulation there is contradiction for efficient outcome. Hence a safe protocol is necessary for implementation. Objectives: To evaluate the most effective, practical and uniform “Anticoagulation Regimen” suited to rural and semi-urban Indian pregnant women with mechanical heart valves with low socio-economic status and to observe its impact on the pregnancy outcomes. Methodology: Retrospective observational cohort study carried out at tertiary institute, between July 2006 to June 2015. 69 women became pregnant during the period from 2006 to 2015 on 1 or multiple occasions. 21(30.43%) pregnancies ended in early abortions and 46 (66.7%) pregnancies were continued. Anticoagulation protocol that was followed in these women was H-A-H protocol. These pregnancies were managed by obstetric team of tertiary care hospital under same consultant. Outcome measures were analyzed. Data was expressed as mean with standard deviation or frequency with percentage as appropriate. Results: Of 292 women, who underwent valve replacement surgery, 69 pregnancies were reported during this period on 1 or multiple occasions. 46 women had successful deliveries and rest 23 had single or multiple pregnancy failure. Incidence of stillbirth in those who delivered successfully was lower (2.89%). Fetal morbidity was 37.68% and none of the pregnant women had valve thrombosis. In 46 women majority had successful outcome except 6(13.04%) children out of 46 who developed anticoagulation related congenital defects. This was mainly seen in those women who presented late in pregnancy. Conclusion: Our Experience showed that Heparin-Acitrome-Heparin protocol is effective and safe in pregnancy than heparin alone, or acitrome alone regimen. The fetal outcome was good, maternal compliance was better and this protocol is widely recommended.

scholarly journals Impact and outcome of cardiac diseases in pregnancy

2020 ◽  
Vol 10 (1) ◽  
pp. 102
Author(s):  
Gira Dabhi ◽  
Jignesh Chauhan ◽  
Munjal Pandya ◽  
Rahul Sinhar
Keyword(s):  
Heart Disease ◽  
Cardiac Disease ◽  
Nyha Class ◽  
Demographic Data ◽  
Tertiary Care ◽  
Mode Of Delivery ◽  
Close Monitoring ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
In Pregnancy

Background: Present study done to study incidence, effect of pregnancy on cardiac disease and vice-versa and feto-maternal outcome in patients with cardiac disease in pregnancy at tertiary care hospital.Methods: It’s a retrospective observational study conducted in Department of OBGY at tertiary care hospital between 01 June 2019 to 31 May 2020. 28 cases of cardiac disease out of 8659 patients registered included in the study. Demographic data like age, parity, etiological factors of cardiac disease, mode of delivery, neonatal outcome noted from case records.Results: In study, 32% were unregistered cases and 10.7% had never sought any medical care before. Majority (53.6%) cases belonged to 20-25 years. Heart disease noted to be more in primipara (35.7%). 71.4% belonged to NYHA class 1+2 and had a relatively uneventful peripartum period. Majority (53.6%) patients had rheumatic valvular disease. Cases of Congenital heart disease were17.8%, pulmonary artery hypertension was 25%, Maternal mortality were 2(7.2%). 46.5% women delivered with caesarean section. PIH (18%) and anemia (7.2%) were most commonly associated conditions. 85.6% women delivered live newborns and full term, pre-term deliveries and IUGR were 71.4%, 17.8% and 10.7% respectively.Conclusions: Rheumatic origin is the most common cardiac disease associated with pregnancy. The availability of early diagnostic techniques and reference to tertiary care centre, timely admission and close monitoring of patient and delivery with multidisciplinary approach include specialized cardiologic care, high risk obstetric support and neonatology expertise can minimize feto-maternal morbidity and mortality. Pre-conceptional counselling, regular antenatal check-ups and contraceptive advice must be included in counselling part.

scholarly journals A RETROSPECTIVE STUDY ON PREVALANCE OF ANEMIA IN PREGNANCY IN A TERITIARY CARE HOSPITAL

2021 ◽  
pp. 106-108
Author(s):  
SYEDA ZAINEB KUBRA HUSSAINI ◽  
BUSHRA SHEREEN ◽  
SIRISHA D ◽  
MADHAVI E ◽  
HARI PRIYA E ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Pregnant Women ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Iron Therapy ◽  
Care Hospital ◽  
Oral Iron Therapy ◽  
Moderate Anemia ◽  
Prevalence Of Anemia ◽  
In Pregnancy

Objective: To study about prevalence in anemia among the antenatal women, its clinical features, and access the severity and its treatment response. Methods: A hospital-based retrospective study on the prevalence of anemia among the antenatal women in tertiary care hospital for 6 months duration in gynecology and obstetrics department. In evaluating pregnant women with anemia, it is essential to do a complete history and physical examination, as well as complete blood count with indices and a blood smear examination. Based on these findings, other test such as ferritin and serum or red cell folate may be ordered. Because of normal physiologic changes in pregnancy that effect the hematocrit, indices, and some other parameters, diagnosing true anemia, as well as the etiology of anemia, is challenging. Results and Discussion: In this retrospective study, the prevalence of Anemia in pregnancy in a tertiary care hospital was evaluated and determined in fifty patients. The most common age group was between 21 and 25 years i.e., (21 patients) 42%. Among 50 patients, majority of them, i.e., 35 patients (70%) were treated with Injection. Iron Sucrose (200 mg). In this study, increase in prevalence were seen majorly in the third trimester, i.e., 25 patients (50%) of which 22 patients (88%) were with moderate anemia with 7.9 gm/dl average hemoglobin (Hb) percentage and 3 patients (12%) were with mild anemia with 9.3 gm/dl average Hb percentage. Conclusion: The plan of management for anemia complicating pregnancy depends on the type of anemia. Oral iron therapy is the route of choice in women with mild to moderate anemia and for severe anemia in pregnant women <30 weeks of gestation. The rise of Hb with parenteral iron therapy is almost the same (avg: 1gm/dl/week) as that of oral iron therapy.

Need for guidelines for the combined management of pregnancy and dengue: a retrospective study from an Indian tertiary care maternity hospital

2018 ◽  
Vol 49 (1) ◽  
pp. 7-9 ◽  
Author(s):  
Sailaja Devi Kallur ◽  
Tarakeswari Surapaneni ◽  
Hari Kishan Boorugu ◽  
Nuzhat Aziz ◽  
Anisha Ramniklal Gala ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Fatal Case ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Dengue Shock Syndrome ◽  
Maternity Hospital ◽  
Close Monitoring ◽  
Hospital Data ◽  
Fetal Outcomes ◽  
In Pregnancy

The incidence of dengue has risen in India in recent years. Evidence suggests that dengue in pregnancy may be associated with adverse maternal and fetal outcomes. The aim of our study was to analyse outcomes in pregnant women with confirmed dengue infection who had the benefit of close monitoring and intensive management at a tertiary maternity facility. We reviewed hospital data of 44 (0.11%) such women at Fernandez Hospital, a tertiary maternity unit, during the five-year period from 2011 to 2016. Maternal and fetal variables were collected from case sheets. Dengue haemorrhagic fever was seen in 15.9% and dengue shock syndrome in one fatal case (2.2%). Thrombocytopenia was seen in 31 cases (70.4%) and 14 (31.81%) received platelets transfusions. Fetal outcomes in our series were favourable, except for one stillbirth, with 45.4% preterm deliveries and 15.9% small for gestational age babies. Dengue in pregnancy is definitely associated with maternal and fetal morbidity and mortality. A high index of suspicion of dengue is required in pregnant women with pyrexia and thrombocytopenia.

scholarly journals Prevalence of thyroid dysfunctions in pregnant women: a prospective study in a tertiary care hospital in Maharashtra, India

2018 ◽  
Vol 7 (8) ◽  
pp. 3211
Author(s):  
Vaishali R. Korde ◽  
Sharin P. Barse ◽  
Jaya S. Barla
Keyword(s):  
Prospective Study ◽  
Pregnant Women ◽  
Thyroid Dysfunction ◽  
Tertiary Care ◽  
Total Sample ◽  
Adverse Outcomes ◽  
Sample Population ◽  
Care Hospital ◽  
A Prospective Study ◽  
In Pregnancy

Background: Thyroid dysfunction is known to be the commonest endocrinological disorder in pregnancy. A range of adverse outcomes in pregnant women and the fetus have been reported. These can be prevented if the thyroid dysfunction is diagnosed and treated as early as possible. There are limited studies conducted on the prevalence of thyroid dysfunction in pregnancy in India. Hence, this study was conducted for assessment of the prevalence of thyroid dysfunction in pregnancy.Methods: The present study is a prospective study conducted in the Department of Obstetrics and Gynecology, MIMER Medical College and Hospital, Talegaon, Dabhade, Maharashtra. The total sample population comprised of 705 pregnant women with uncomplicated singleton intra-uterine pregnancy. All participants were screened by estimation for serum TSH in first trimester.Results: The prevalence of thyroid dysfunction in the present study is 13.9%. Of this, prevalence of hypothyroidism is 12.76% and that of hyperthyroidism is 1.13%.Conclusions: With this study, we conclude that there is high prevalence of thyroid dysfunction in pregnancy even in rural population. Thus, a universal screening helps in early diagnosis and preventing the aftermaths of thyroid dysfunction in pregnancy.

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