scholarly journals The Relationship between Hypertension and Cognitive Function Impairment in the Elderly

2019 ◽  
Vol 7 (9) ◽  
pp. 1440-1445 ◽  
Author(s):  
Endy Juli Anto ◽  
Laura Oktavina Siagian ◽  
Jekson Martiar Siahaan ◽  
Hendrika Andriana Silitonga ◽  
Sony Eka Nugraha
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Function ◽  
Nursing Homes ◽  
Significant Relationship ◽  
The Elderly ◽  
Research Approach ◽  
Impaired Cognitive Function ◽  
Function Impairment ◽  
The Relationship ◽  
Second Degree

BACKGROUND: Hypertension is still a health problem both in developed and developing countries. Hypertension can cause various complications; one of them is cognitive function impairment. AIM: This study aimed to look at the relationship of hypertension with cognitive function. This research can also be useful to help optimise the health of the elderly, maximise quality of life and avoid hypertension as a risk factor for cognitive impairment in the elderly at the Karya Kasih Nursing Homes, Medan from May to June 2018. METHODS: This research was carried out by analytic observational with cross-sectional research approach. In this study, 57 elderly from Karya Kasih Nursing Homes Medan who met the inclusion and exclusion criteria participated. Assessment of cognitive function used Mini-Mental State Examination (MMSE), Six Item Cognitive Impairment Test (6CIT) and Abbreviated Mental Test Score (AMT) instruments. RESULT: This study obtained a significant relationship between the history of hypertension with impaired cognitive function (p = 0.003). The results of the cognitive function examination with MMSE showed that among 57 elderly, 16 people (43.2%) were normal and 21 people (56.8%) had impaired cognitive function in the first degree hypertension group, besides that, 3 people were normal (15%) and 7 people (85%) had impaired cognitive function in the second degree hypertension group (p = 0.031). Based on the result of mild and severe cognitive function impairment, among 12 people (57.1%) and 9 people (42.9%) had a mild and severe cognitive function impairment, respectively, in first-degree hypertension. 3 people (17.6%) and 14 people (82.4%) had a mild and severe cognitive function impairment, respectively, in the second-degree hypertension (p = 0.013). The 6-CIT instrument also showed a significant relationship between the severity of hypertension and impaired cognitive function (p = 0.027), and there was no significant relationship with AMT instruments (p = 0.078). CONCLUSION: There was a relationship between the history or duration and degree of hypertension with cognitive dysfunction in the elderly at the Karya Kasih Nursing Home Medan.

scholarly journals Consumption of Food Sources of Antioxidant Associated with Cognitive Function and Oxidative Stress Markers 4-HNE

2020 ◽  
Vol 13 (4) ◽  
pp. 2049-2053
Author(s):  
Faradila Faradila ◽  
Ratna Deliana Siregar ◽  
NurIndrawaty Liputo
Keyword(s):  
Oxidative Stress ◽  
Cognitive Function ◽  
Significant Relationship ◽  
Plasma Levels ◽  
Statistical Tests ◽  
The Elderly ◽  
Food Sources ◽  
Chi Square ◽  
Cross Sectional ◽  
Impaired Cognitive Function

Background and Aim : The contain of antioxidant in vegetables, fruits, spices, and tea has a protective effect from oxidative stress which can cause impaired cognitive function.This study aimed todetermine the relationship between the consumption of antioxidant-rich foods such as vegetables, fruits, spices, and tea with 4-HNE plasma levels and cognitive function of elderly. Material and method : The study design was cross-sectional, and was conducted in the Lima Puluh Kota district, West Sumatra in 2018.Interviewing antioxidant food intake was carried out using the Food Frequency Questioner (FFQ), cognitive function was assessed by the Indonesian version of the Montreal Cognitive Assessment (MoCA-Ina), plasma 4-HNE was measured by the ELISA method. Finally, the data was analyzed by Mann-Whitney and Chi-square statistical tests. Result :The result showed that 83 elderly (57.2%) experience impaired cognitive function. There was no significant relationship between consumption of antioxidant foods and plasma levels of HNE. However, consumption of vegetables, fruits, spices, and tea has a significant relationship with cognitive function. Conclusion:This study concluded that consumption of vegetables, fruits, spices, and tea can protect the elderly from impaired cognitive function.

scholarly journals Relationship of Serum Tau Levels with Cognitive Functions and Factors Affecting The Cognitive Function Decrease in Parkinson's Disease Patients

2021 ◽  
Vol 5 (3) ◽  
pp. 539-545
Author(s):  
Meldayeni Busra ◽  
Yuliarni Syafrita ◽  
Hendra Permana
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Tau Protein ◽  
Significant Relationship ◽  
Education Level ◽  
Motor Symptom ◽  
Categorical Variables ◽  
The Relationship

Introduction: Cognitive impairment is a non-motor symptom of Parkinson's disease (PD) which occurs as the disease progresses and affects quality of life. Many efforts have been developed in early detection of cognitive disorders, one of which is the examination of tau protein biomarkers, where the tau protein that undergoes pathological changes to form neurofibrillary tangles (NFTs) is found in Alzheimer's disease and PD and plays a role in cognitive impairment. However, the role of tau in PD is still controversial. This study aims to assess the relationship between serum tau levels and cognitive function and the factors that affect cognitive function in PD patients. Methods: This cross-sectional design was conducted at the RSUP DR. M Djamil Padang. During the period March to August 2020, 62 research subjects were obtained. Cognitive function examination was carried out by using the MoCA-Ina test and examination of serum tau levels using the Elisa method. The relationship between categorical variables was tested by Chi square and differences in serum tau levels in the group with and without cognitive impairment were tested with the Mann Whitney test, considered statistically significant if the p value <0.05. Results: With Moca Ina examination, it was found that 67.7% of patients had impaired cognitive function. The mean serum tau level was 198.004 ± 162.69 ng / L.There was a significant relationship between education level and degree of disease with cognitive function (p <0.05) and there was no difference in mean serum tau levels between groups with and without cognitive impairment. Conclusion: There is a significant relationship between education level and degree of disease with cognitive function and there is no difference in mean serum tau protein levels between the cognitive impaired group and the cognitive normal group.

scholarly journals P0798ASSOCIATION BETWEEN RENAL DYSFUNCTION AND GENERAL COGNITIVE FUNCTION IN COMMUNITY DWELLING OLDER ADULTS: KOREAN FRAILTY AND AGING COHORT STUDY

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Jiyoon Kong ◽  
Jin Sug Kim ◽  
Min Hye Kang ◽  
Shin Yeong Kang ◽  
Ri Ra ◽  
...  
Keyword(s):  
Older Adults ◽  
Renal Function ◽  
Cohort Study ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Renal Dysfunction ◽  
The Elderly ◽  
Community Dwelling ◽  
Community Dwelling Older Adults ◽  
The Relationship

Abstract Background and Aims Cognitive impairment is common in older adults. Similarly, the prevalence of renal dysfunction is also increased in the elderly. We conducted this study to clarify the relationship between the renal function and cognitive impairment in community dwelling older adults in Korea. Method A cross-sectional analysis was performed on the data of the Korean Frailty and Aging Cohort Study (KFACS), a nationwide cohort study that began in 2016. Of the 3014 participants assessed in the first and second year, 2847 participants (1333 men, 1514 women) who completed baseline assessments were enrolled. The estimated glomerular filtration rate (eGFR, mL/min/1.73m2) was calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. Renal function of the participants was classified into four groups by eGFR quartile. General cognitive function was accessed with mini-mental state exam in the Korean version (MMSE-KC). Participants who had MMSE-KC score less than 1.5 standard deviation by age, gender, and education level were regarded as the cognitive impairment. Multivariate logistic regression model was used to examine the relationship between renal function and cognitive impairment. In addition, we investigated to find the point of eGFR interval at which the odds ratio begins to increase. Results The mean eGFR in quartile 1 was 91.7 ± 3.22 ml/min/1.73m2, and 84.9 ± 1.81 in quartile 2, 76.1 ± 3.66 in quartile 3, and 57.2 ± 10.75 in quartile 4. In baseline characteristics, participants with lower eGFR had lower MMSE-KC scores. And the prevalence of cognitive impairment was 10.8% in quartile 1, 15.9% in quartile 2, 15.2% in quartile 3, 14.9% in quartile 4. After multivariate adjustment, the odds ratio (OR) of cognitive impairment in quartile 2 [adjusted OR: 1.569, 95% confidence intervals (CI): 1.141 - 2.158, p = 0.006] compared with quartile 1. And the odd ratios of cognitive impairment were 1.539 (95% CI: 1.113 - 2.127, p = 0.009) in quartile 3, 1.475 (95% CI: 1.062 - 2.049, p = 0.020) in quartile 4 compared with quartile 1, respectively. Among the participants with eGFR above 60 ml/min/1.73m2, the renal function was grouped by 5 ml/min/1.73m2 interval. The risk of cognitive impairment started to increase from eGFR between 80 and 85 ml/min/1.73m2 (adjusted OR: 1.667, 95% CI: 1.128 - 2.463, p = 0.010). Conclusion Renal dysfunction was associated with lower global cognitive function in older adults. And the risk of cognitive impairment increased from quartile 2, especially, eGFR between 80 and 85 ml/min/1.73m2 in this population. These results suggest that mild decline of kidney function is also a risk factor of cognitive decline in the elderly.

scholarly journals Relationship of Serum Tau Levels with Cognitive Functions and Factors Affecting The Cognitive Function Decrease in Parkinson's Disease Patients

2021 ◽  
Vol 5 (6) ◽  
pp. 513-519
Author(s):  
Meldayeni Busra ◽  
Yuliarni Syafrita ◽  
Hendra Permana
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Tau Protein ◽  
Significant Relationship ◽  
Education Level ◽  
Motor Symptom ◽  
Categorical Variables ◽  
The Relationship

Introduction: Cognitive impairment is a non-motor symptom of Parkinson's disease (PD) which occurs as the disease progresses and affects quality of life. Many efforts have been developed in early detection of cognitive disorders, one of which is the examination of tau protein biomarkers, where the tau protein that undergoes pathological changes to form neurofibrillary tangles (NFTs) is found in Alzheimer's disease and PD and plays a role in cognitive impairment. However, the role of tau in PD is still controversial. This study aims to assess the relationship between serum tau levels and cognitive function and the factors that affect cognitive function in PD patients. Methods: This cross-sectional design was conducted at the RSUP DR. M Djamil Padang. During the period March to August 2020, 62 research subjects were obtained. Cognitive function examination was carried out by using the MoCA-Ina test and examination of serum tau levels using the Elisa method. The relationship between categorical variables was tested by Chi square and differences in serum tau levels in the group with and without cognitive impairment were tested with the Mann Whitney test, considered statistically significant if the p value <0.05. Results: With Moca Ina examination, it was found that 67.7% of patients had impaired cognitive function. The mean serum tau level was 198.004 ± 162.69 ng / L.There was a significant relationship between education level and degree of disease with cognitive function (p <0.05) and there was no difference in mean serum tau levels between groups with and without cognitive impairment. Conclusion: There is a significant relationship between education level and degree of disease with cognitive function and there is no difference in mean serum tau protein levels between the cognitive impaired group and the cognitive normal group.

scholarly journals Association between change in handgrip strength and cognitive function in Korean adults: a longitudinal panel study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hyunkyu Kim ◽  
Seung Hoon Kim ◽  
Wonjeong Jeong ◽  
Sung-In Jang ◽  
Eun-Cheol Park ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Function ◽  
Handgrip Strength ◽  
Panel Study ◽  
Continuous Variable ◽  
South Korean ◽  
Korean Adults ◽  
Strength Change ◽  
The Relationship ◽  
State Examination

Abstract Background Muscular function, such as handgrip strength, has been suggested as an associated factor for cognitive impairment. This study investigated the association between temporal change in handgrip strength and cognitive function using longitudinal, nationwide data from Korean older adults. Methods Our study used data from the Korean Longitudinal Study of Aging (KLoSA). The analysis covered 6696 participants who had taken the handgrip strength test and Mini-Mental State Examination (MMSE) from 2006 to 2018. We adopted general estimating equations to assess the temporal effect of handgrip strength change on cognitive function. Results After adjusting for covariates, we observed an association between handgrip strength and low MMSE scores (β = − 0.3142 in men, β = − 0.2685 in women). Handgrip strength as a continuous variable was positively correlated with MMSE scores after adjustment (β = 0.0293 in men, β = 0.0347 in women). The group with decreased handgrip strength over time also showed greater odds for mild cognitive impairment (OR = 1.23, 95%CI = 1.05–1.27 in men, OR = 1.15, 95%CI = 1.05–1.27 in women) and dementia (OR = 1.393, 95%CI = 1.18–1.65 in men, OR = 1.19, 95%CI = 1.08–1.32 in women). Conclusions This study identified the relationship between handgrip strength change and cognitive function among South Korean adults. According to our large, longitudinal sample, decreasing handgrip strength was associated with decline in cognitive function.

scholarly journals Analisis Motor Educability Dan Kelincahan Dengan Keterampilan Menggiring Bola Dalam Permainan Futsal

2019 ◽  
Vol 3 (1) ◽  
pp. 75
Author(s):  
Sudirman Sudirman
Keyword(s):  
Data Analysis ◽  
Data Reduction ◽  
Significant Relationship ◽  
Quantitative Approach ◽  
Research Approach ◽  
Motor Ability ◽  
Research Focus ◽  
Analysis Techniques ◽  
The Relationship

ABSTRACTThe problem in this research is motor educability and agility with dribbling skills in soccer games at the BKMF Futsal FIK UNM. The formulation of the problem in this study is “is there a relationship between motor Educability and agility with dribbling skills in soccer games at BKMF Futsal FIK UNM?”. The research objective was to determine the relationship between Motor Educability and agility with dribbling skills in games at the BKMF Futsal FIK UNM. The research approach is a quantitative approach that is descriptive in nature. While the research focus is Motor Educability and agility with dribbling skills in games at the BKMF Futsal FIK UNM, the data used are tests and documentation. Data analysis techniques consist of data reduction, data exposure and drawing conclusions. The results of the study (1) Motor ability has a significant relationship with dribbling skills in futsal games at BKMF Futsal FIK UNM. (2) Agility has a significant relationship with dribbling skills in futsal games at BKMF Futsal FIK UNM. (3) Motor ability and agility have a significant relationship with dribbling skills in futsal games at BKMF Futsal FIK UNM. ABSTRAKPermasalahan dalam penelitian ini adalah Motor Educability dan kelincahan dengan keterampilan menggiring bola dalam permainan futsal pada Mahasiswa BKMF Futsal FIK UNM. Rumusan masalah dalam penelitian ini yaitu “Apakah terdapat hubungan Motor Educability dan kelincahan dengan keterampilan menggiring bola dalam permainan futsal pada Mahasiswa BKMF Futsal FIK UNM?”. Tujuan penelitian yaitu Untuk mengetahui hubungan Motor Educability dan kelincahan dengan keterampilan menggiring bola dalam permainan futsal pada Mahasiswa BKMF Futsal FIK UNM. Pendekatan penelitian yaitu pendekatan kuantitatif yang bersifat deskriptif. Sementara  fokus penelitian adalah Motor Educability dan kelincahan dengan keterampilan menggiring bola dalam permainan futsal pada Mahasiswa BKMF Futsal FIK UNM data yang digunakan yaitu  tes dan dokumentasi. Teknik analisis data terdiri dari reduksi data, paparan data dan penarikan kesimpulan. Hasil penelitian (1) Motor educability memiliki hubungan yang signifikan dengan keterampilan menggiring bola dalam permainan futsal pada BKMF Futsal FIK UNM. (2) Kelincahan memiliki hubungan yang signifikan dengan keterampilan menggiring bola dalam permainan futsal pada BKMF Futsal FIK UNM. (3) Motor educability dan kelincahan memiliki hubungan yang signifikan dengan keterampilan menggiring bola dalam permainan futsal pada BKMF Futsal FIK UNM

scholarly journals Pengaruh Metode Role playing untuk Meningkatkan Motivasi pada Pembelajaran Bahasa Indonesia kelas IV di MI Annidhomiyah Astanajapura

2021 ◽  
Vol 2 (1) ◽  
pp. 42
Author(s):  
Somantri Somantri ◽  
M. Zaeni
Keyword(s):  
Student Learning ◽  
Learning Process ◽  
Significant Relationship ◽  
Student Motivation ◽  
Role Playing ◽  
Learning Motivation ◽  
Research Approach ◽  
Learning Method ◽  
The Relationship ◽  
Bahasa Indonesia

This study uses correlation research. The research approach used is a quantitative approach. The low student motivation is due to the unattractive use of the learning method causing the students to be overwhelmed by feelings of boredom and boredom, so that what the teacher says is not paid attention. The role playing method has a relationship with student learning motivation. This method is when the learning process without a good role playing method, learning will not be effective and will not foster student motivation to the fullest. To test the hypothesis, testing was carried out by calculating t from the tcount of 5,334 which was then consulted with ttable 2.030, then tcount 5.334 ≥ ttable 2.030, which means that the relationship that occurs between variable X (role playing method) and variable Y (student learning motivation) is a relationship significant. Thus it can be concluded that there is a positive and significant relationship between the role playing method with student learning motivation at MI Annidhomiyah Japura Kidul. Abstrak Penelitian ini menggunakan penelitian korelasi. Pendekatan penelitian yang digunakan adalah pendekatan kuantitatif. Rendahnya motivasi belajar siswa disebabkan tidak menariknya cara penggunaan  metode pembelajaran menyebabkan para siswa diliputi oleh rasa bosen dan jenuh, sehingga apa yang guru sampaikan tidak diperhatikan. Metode role playing  mempunyai hubungan terhadap motivasi belajar siswa. Metode ini saat proses pembelajaran tanpa metode role playing  yang baik, pembelajaran tidak akan bisa efektif dan tidak menumbuhkan motivasi belajar siswa dengan maksimal. Untuk uji hipotesis maka  dilakukan pengujian dengan penghitungan thitungdari hasil penghitungan thitung 5,334 yang kemudian dikonsultasikan dengan ttabel 2,030 maka thitung 5,334 ≥ ttabel 2,030, yang artinya bahwa hubungan yang terjadi antara variabel X ( Metode role playing)  dengan variabel Y ( motivasi belajar siswa ) adalah hubungan yang signifikan. Dengan demikian dapat disimpulkan bahwa terdapat hubungan positif dan signifikan dari Metode role plyaing deangan motivasi belajar siswa di MI Annidhomiyah Japura Kidul

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