scholarly journals Syzygium aromaticum water extract attenuates ethanol-induced gastric injury through antioxidant effects in rats

2016 ◽  
Vol 14 (1) ◽  
pp. 361-366 ◽  
Author(s):  
SEONG EUN JIN ◽  
MEE-YOUNG LEE ◽  
IN-SIK SHIN ◽  
WOO-YOUNG JEON ◽  
HYEKYUNG HA
Proceedings ◽  
2019 ◽  
Vol 40 (1) ◽  
pp. 23
Author(s):  
Zengin ◽  
Aygun ◽  
Aktumsek

Nowadays, knowledge of ancient botanical medicinal practices and application of modern phytochemical techniques have provided the excellent tools for the purification and structural elucidation of various phyto-compounds, which, in turn, has given insights into their mode of action on the human body. This study has been designed to investigate for the first time the antioxidant effects of the ethyl acetate, methanolic, and water extracts of Kitaibelia balansae. Different chemical methods were performed and the observed abilities depend on the solvent used. The best antioxidant ability was noted in water extract, followed by methanol and ethyl acetate extracts. The highest level of phenolic was also detected in water extract. The present findings suggest that K. balansae can be considered as a potential source of bioactive compounds for novel phytopharmaceuticals development


Andrologia ◽  
2019 ◽  
Vol 51 (11) ◽  
Author(s):  
Maria Valéria de Oliveira Santos ◽  
Andréia Maria Silva ◽  
Érika Almeida Praxedes ◽  
Alana Azevedo Borges ◽  
Antônio Carlos de Albuquerque Teles Filho ◽  
...  

Nutrients ◽  
2016 ◽  
Vol 8 (3) ◽  
pp. 155 ◽  
Author(s):  
Huayi Suo ◽  
Xin Zhao ◽  
Yu Qian ◽  
Peng Sun ◽  
Kai Zhu ◽  
...  

2013 ◽  
Vol 3 (9) ◽  
pp. 332 ◽  
Author(s):  
M. Adel El-Sayed ◽  
Radwan BaAbbad ◽  
Amal Balash ◽  
Nasser A. Al-Hemdan ◽  
Abdullah Softah

Artemisia judaica (AJ) is one of the common species of the genus Artemisia that grows in Saudi Arabia desert and Sinai, Egypt where animals graze on it. It is widely used in traditional medicine and by Bedouins there. (AJ) has anthelmintic, antibacterial, antiinflammatory, analgesic and antipyretic effects. The present study aimed to (1) elucidates the antibacterial action of AJ against H. pylori and different other bacterial species (2) delineate the potential antibacterial mechanism of action of AJ in comparison with tetracycline and cefotaxime (3) measure the trolox equivalent antioxidant capacity (TEAC) of the AJ water extract. Preparation of the (AJ) extracts was done by three different methods two of them are usually performed by population in Middle East by boiling of the shade-dried herb in water as tea (decoction), or soaked in tap water for over night (infusion), other method was done by concentrating the aqueous extract of Artemisia judaica under vacuum. The results of this study revealed that (AJ) has neither antibacterial effects either against H. pylorinor any other bacterial species. On the other hand the extract of AJ prepared by any of the above mentioned methods shows significant (p<0.005) antioxidant action as compared with blank and related to trolox antioxidant capacity.


2000 ◽  
Vol 28 (01) ◽  
pp. 87-96 ◽  
Author(s):  
Chun-Ching Lin ◽  
Pei-Chen Huang ◽  
Jer-Min Lin

Anoectochilus formosanus Hay. and Gynostemma pentaphyllum Makino are popular folk medicines that have been used for treating hepatitis, hypertension and cancer in Taiwan. Our previous studies showed that these crude drugs exert antiinflammatory activity and hepatoprotective activity against CCI4-induced liver damage. In this study, the antioxidant effect of these crude drugs and their hepatoprotective activity on acetaminophen-induced liver injury in rat was evaluated. Our results suggest that A. formosanus and G. pentaphyllum do have antioxidant effects. On acetaminophen-intoxicated model, the increased levels of aspartate aminotransferase (AST) and alanine aminotrans-ferase (ALT) by acetaminophen administration were reduced by treatment with these two herbs. In histological observation, gross necrosis in the centribular area, sinusoidal congestion, infiltration of the lymphocytes and Kupffer cells around the hepatic central vein, and loss of cell boundaries and ballooning degeneration were reduced with herbal treatment. However, the effect of A. formosanus and G. pentaphyllum is biphasic. Methanol extract (100 and 300 mg/kg) and water extract (300 and 500 mg/kg) of A formosanus and water extract (100, 300 and 500 mg/kg) of G. pentaphyllum enhanced the recovery of liver injury while treatment with 500 mg/kg of A. formosanus methanol extract resulted in serious hepatic injury.


2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Xue Wu ◽  
Qionghui Huang ◽  
Nan Xu ◽  
Jian Cai ◽  
Dandan Luo ◽  
...  

Acrostichum aureum Linn., a medicinal pteridophyte growing in mangrove forests and coastal regions of tropical and subtropical areas worldwide, has been proved to possess various biological effects. However, the protective effect of Acrostichum aureum Linn. against gastric ulcer still remains unidentified. Therefore, the gastroprotective effect of the water extract of Acrostichum aureum Linn. (WEAC) was investigated in ethanol-induced gastric injury model. According to our results, pretreatment with WEAC (100, 200, and 400 mg/kg) could dramatically decrease the ulcer areas and ameliorate the pathological damage induced by alcohol in rat’s gastric tissues. In addition, WEAC administration prevented the stomach from oxidative damage via markedly increasing the levels of glutathione (GSH), superoxide dismutase (SOD), catalase (CAT), and decreasing the malondialdehyde (MDA). Besides, WEAC pretreatment alleviated inflammatory infiltration by reducing the secretion of proinflammatory cytokines including tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6) as well as decreasing the protein expressions of phosphorylation of IκBα and p65. Taken together, WEAC exerted potential therapeutic efficacy for gastric ulceration, and this may be involved in the suppression of oxidative stress and inflammatory response.


2014 ◽  
Vol 14 (3) ◽  
pp. 237-243 ◽  
Author(s):  
Meejung Ahn ◽  
Yoonhyoung Kang ◽  
Jihwan Moon ◽  
Seungjoon Kim ◽  
Changjong Moon ◽  
...  

2016 ◽  
Vol 3 (2) ◽  
pp. 117
Author(s):  
Samsudin Samsudin ◽  
Funny Soesanthy ◽  
Syafaruddin Syafaruddin

<p>Ephestia cautella<em> is one </em><em>type </em><em>of storage pest</em><em>s</em><em> that causes a decrease in cocoa bean</em><em> </em><em>quality. Control of th</em><em>is</em><em> pest using chemical insecticides is not recommended because it is harmful to the environment and consumer health. The research aimed to </em><em>examine</em><em> the repellency and insecticidal activity of several types of extract and botanical oil </em><em>against</em><em> </em>E. cautella<em> larvae. The </em><em>research was</em><em> conducted </em><em>in</em><em> the Plant Protection Laboratory, Indonesian Industrial and Beverage Crops Research Institute, </em><em>from </em><em>March to November 2012. </em><em>Botanical</em><em> materials used </em><em>were</em><em> water extracts from </em>Ageratum conyzoides<em> leaves, </em>Azadirachta indica<em> seeds, </em><em>and </em>Allium sativum<em> tubers, as well as oil from </em>Reutalis trisperma<em>, </em>Syzygium aromaticum<em>, and </em>Andropogon nardus<em>, </em><em>with respective</em><em> concentration of 0.5%. The insects test used was the 3rd instar larvae </em><em>generated</em><em> in the laboratory. </em><em>P</em><em>reliminary testing </em><em>of the </em><em>repellency activity was performed </em><em>used the</em><em> multiple</em><em>-</em><em>choice method, while subsequent testing used the dual</em><em>-</em><em>choice method with the parameter</em><em>s</em><em> of larvae </em><em>number remains i</em><em>n each treatment until 72 hours. The insecticidal activity was conducted using residual </em><em>method </em><em>on the feed substitute, by calculating mortality rate of the test insects. Observations were made at 24, 48, and 72 hours after treatment. The results showed that water extract </em><em>from</em><em> </em>A. sativum<em> bulbs and </em>A. conyzoides<em> leaves have high repellency percentage on the  </em>E. cautella<em> larvae, i.e. </em><em>of </em><em>81.33% and 78.67%, respectively. Thus, the</em><em>se</em><em> two vegetable extracts have the potential to be </em><em>used as cocoa bean protectant </em><em>from </em><em>storage pest </em><em>attack</em><em>s.</em><em> The extract</em><em>s</em><em> </em><em>from</em><em> </em>A. indica<em> seed, </em>A. sativum<em> bulbs, as well as</em><em> oil from</em><em> </em>R. trisperma<em> and </em>S. aromaticum<em> showed insecticidal properties that are able to kill </em>E. cautella<em> larvae.</em><em></em></p>


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