The Prevalence, Incidence, and Progression of Hand Osteoarthritis in Relation to Body Mass Index, Smoking, and Alcohol Consumption

Objective.To estimate the extent that overweight/obesity, smoking, and alcohol are associated with prevalence and longitudinal changes of radiographic hand osteoarthritis (OA).Methods.Participants from the Osteoarthritis Initiative (n = 1232) were included, of whom 994 had 4-year followup data. In analyses on incident hand OA, only persons without hand OA at baseline were included (n = 406). Our exposure variables were overweight/obesity [body mass index (BMI), waist circumference], smoking (current/former, smoking pack-yrs), and alcohol consumption (drinks/week). Using linear and logistic regression analyses, we analyzed possible associations between baseline exposure variables and radiographic hand OA severity, erosive hand OA, incidence of hand OA, and radiographic changes. Analyses were adjusted for age, sex, and education.Results.Neither overweight nor obesity were associated with hand OA. Current smoking was associated with less hand OA in cross-sectional analyses, whereas longitudinal analyses suggested higher odds of incident hand OA in current smokers (OR 2.20, 95% CI 1.02–4.77). Moderate alcohol consumption was associated with higher Kellgren-Lawrence sum score at baseline (1–3 drinks: 1.55, 95% CI 0.43–2.67) and increasing sum score during 4-year followup (4–7 drinks: 0.33, 95% CI 0.01–0.64). Moderate alcohol consumption (1–7 drinks/week) was associated with 2-fold higher odds of erosive hand OA, which was statistically significant. Additional adjustment for BMI gave similar strengths of associations.Conclusion.Overweight/obesity were not associated with hand OA. Contrasting results were observed for smoking and hand OA, suggesting lack of association. Moderate alcohol consumption was associated with hand OA severity, radiographic changes, and erosive hand OA, warranting further investigation.

Download Full-text

Alcohol intake in relation to body mass index and waist-to-hip ratio: the importance of type of alcoholic beverage

Public Health Nutrition ◽

10.1079/phn2004680 ◽

2005 ◽

Vol 8 (3) ◽

pp. 315-320 ◽

Cited By ~ 69

Author(s):

Esther Lukasiewicz ◽

Louise I Mennen ◽

Sandrine Bertrais ◽

Nathalie Arnault ◽

Paul Preziosi ◽

...

Keyword(s):

Body Mass Index ◽

Alcohol Consumption ◽

Body Mass ◽

Alcoholic Beverage ◽

Alcoholic Beverages ◽

Cross Sectional ◽

Men And Women ◽

Waist To Hip Ratio ◽

Dietary Records ◽

Total Alcohol

AbstractObjectiveAlcohol consumption may play a role in the development of obesity but the relationship between alcohol and weight is still unclear. The aim of our study was to assess the cross-sectional association of intakes of total alcohol and of specific alcoholic beverages (wine, beer and spirits) with waist-to-hip ratio (WHR) and body mass index (BMI) in a large sample of adults from all over France.DesignCross-sectional.SettingParticipants were free-living healthy volunteers of the SU.VI.MAX study (an intervention study on the effects of antioxidant supplementation on chronic diseases).SubjectsFor 1481 women aged 35–60 years and 1210 men aged 45–60 years, intakes of total alcohol and specific alcoholic beverages were assessed by six 24-hour dietary records. BMI and WHR were measured during a clinical examination the year after.ResultsA J-shaped relationship was found between total alcohol consumption and WHR in both sexes and between total alcohol consumption and BMI in men only (P < 0.05). The same relationships were observed with wine (P < 0.05); men and women consuming less than 100 g day−1 had a lower BMI (men only) and WHR than non-drinkers or those consuming more. Spirits consumption was positively associated with BMI (linear regression coefficient β = 0.21, 95% confidence interval (CI): 0.09–0.34 and β = 0.22, 95% CI: 0.06–0.39 for men and women, respectively) and WHR (β = 0.003, 95% CI: 0.001–0.005 and β = 0.003, 95%CI: 0.0002–0.006) in both sexes in a linear fashion. No relationship between beer consumption and BMI or WHR was found.ConclusionIf confirmed in longitudinal studies, our results indicate that consumption of alcoholic beverages may be a risk factor for obesity.

Download Full-text

A Cross-Sectional Study on Pattern of Alcohol Consumption and Body Mass Index Among Health Institution Students in Bagalkot

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2015/15269.6905 ◽

2015 ◽

Author(s):

Vetri Selvan T

Keyword(s):

Body Mass Index ◽

Alcohol Consumption ◽

Body Mass ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Health Institution

Download Full-text

Prevalence and Risk Factors of Asymptomatic Colorectal Polyps in Taiwan

Gastroenterology Research and Practice ◽

10.1155/2014/985205 ◽

2014 ◽

Vol 2014 ◽

pp. 1-8 ◽

Cited By ~ 9

Author(s):

Fu-Wei Wang ◽

Ping-I Hsu ◽

Hung-Yi Chuang ◽

Ming-Shium Tu ◽

Guang-Yuan Mar ◽

...

Keyword(s):

Risk Factors ◽

Body Mass Index ◽

Alcohol Consumption ◽

Body Mass ◽

High Body Mass Index ◽

Colorectal Polyps ◽

Adenomatous Polyps ◽

Hyperplastic Polyps ◽

Current Smoking ◽

Asymptomatic Subjects

Purpose. To investigate the prevalence and risk factors of hyperplastic and adenomatous colorectal polyps in a Taiwanese general population.Methods. From January 2009 to December 2011, consecutive asymptomatic subjects undergoing a routine health check-up were evaluated by colonoscopy. The colorectal polyps were assessed, and medical history and demographic data were obtained from each patient. Logistic regression analysis was conducted to search the independent risk factors for asymptomatic hyperplastic and adenomatous colorectal polyps.Results. Of the 1899 asymptomatic subjects, the prevalences of hyperplastic polyps and adenomatous polyps were 11.1% and 16.1%, respectively. Multivariate analysis revealed that high body mass index (BMI>25: OR, 1.32, 95% CI, 1.05–1.71) and current smoking (OR, 1.87, 95% CI, 1.42–2.71) were independent predictors for hyperplastic colorectal polyps. Age over 60 years old (OR, 3.49, 95% CI, 1.86–6.51), high body mass index (BMI>25: OR, 1.75, 95% CI, 1.21–2.71), heavy alcohol consumption (OR, 2.01, 95% CI, 1.02–3.99), and current smoking (OR, 1.31, 95% CI, 1.04–1.58) were independent predictors for adenomatous colorectal polyps.Conclusion. High BMI and smoking are common risk factors for both adenomatous and hyperplastic polyps. Old age and alcohol consumption are additional risk factors for the development of adenomatous polyps.

Download Full-text

Association of Body Mass Index and Serum Markers of Tissue Damage with Postoperative Pain. The Role of Lactate Dehydrogenase for Postoperative Pain Prediction

Pain Medicine ◽

10.1093/pm/pnz325 ◽

2019 ◽

Vol 21 (8) ◽

pp. 1636-1643 ◽

Cited By ~ 1

Author(s):

Cristina González-Callejas ◽

Virginia A Aparicio ◽

Carlos De Teresa ◽

Teresa Nestares

Keyword(s):

Body Mass Index ◽

Lactate Dehydrogenase ◽

Postoperative Pain ◽

Alcohol Consumption ◽

Body Mass ◽

Tissue Damage ◽

Smoking Habit ◽

Serum Markers ◽

Cross Sectional ◽

Severe Postoperative Pain

Abstract Objectives i) To analyze the association of body mass index (BMI) and some serum tissue damage markers with postoperative pain. ii) To establish a biochemical marker cutoff point able to predict moderate to severe postoperative pain. Design Cross-sectional study. Subjects Ninety-six adult male patients from Southern Spain (55 ± 13 years old) who underwent an inguinal hernioplasty. Methods Postoperative pain (eight hours after surgery) was assessed through a visual analog scale (VAS). Moderate to severe pain was defined as a VAS > 50 mm. BMI was calculated and medication, alcohol consumption, and smoking habit registered. Eight hours after surgery, some serum markers such as fibrinogen, lactate dehydrogenase (LDH), C-reactive protein, cortisol, creatine kinase, glutamic-pyruvic, glutamic oxaloacetic, and gamma-glutamyltransferase transaminases were determined by standard procedures. Results After adjusting for potential confounders, BMI was not associated with postoperative pain (P > 0.05). Serum fibrinogen was associated with greater postoperative pain (β = 0.333, P < 0.05). Serum LDH concentration was strongly associated with greater postoperative pain (β = 0.606, P < 0.001). Alcohol consumption was associated with higher postoperative pain (β = 0.212, P < 0.05). No associations were observed regarding age, tobacco consumption, and the rest of serum markers studied. Serum LDH concentration was able to discriminate between presence/absence of moderate to severe postoperative pain (receiver operating characteristic area under the curve = 0.655, P ≤ 0.01). An LDH concentration >204 IU/L was associated with a three-times increased odds ratio of moderate to severe postoperative pain. Conclusions Contrary to expectations, greater BMI was not associated with higher postoperative pain. Notwithstanding, the assessment of serum LDH might provide useful information to predict moderate to severe postoperative pain.

Download Full-text

Did COVID-19 Pandemic Change People’s Physical Activity Distribution, Eating, and Alcohol Consumption Habits as well as Body Mass Index?

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph182312405 ◽

2021 ◽

Vol 18 (23) ◽

pp. 12405

Author(s):

Albertas Skurvydas ◽

Ausra Lisinskiene ◽

Marc Lochbaum ◽

Daiva Majauskiene ◽

Dovile Valanciene ◽

...

Keyword(s):

Physical Activity ◽

Body Mass Index ◽

Alcohol Consumption ◽

Body Mass ◽

Cross Sectional Study ◽

Cross Sectional ◽

Activity Distribution ◽

Metabolic Equivalent Of Task ◽

Sport Clubs ◽

Consumption Habits

This cross-sectional study aimed to evaluate whether COVID-19 had an impact on people’s (aged 18–74) physical activity distribution, eating, and alcohol consumption habits as well as body mass index. We interviewed 6369 people (4545 women and 1824 men) in Lithuania before the COVID-19 pandemic started and 2392 during COVID-19 (1856 women and 536 men). They were aged 18–74 years. We found that both genders had not stopped their physical activity (PA) completely because of lockdown imitations (for example, prohibition from attending sport clubs), but they started doing different physical exercises at sport clubs. We determined the PA distribution according to the Danish Physical Activity Questionnaire (DPAQ). Despite increases in independent PA and the quantity of light PA, the amount of total energy used in metabolic equivalent of task (MET) units per day decreased significantly for both genders irrespective of age. Although the amounts of sedentary behavior, moderate PA (MPA), vigorous PA (VPA) or a combination of MPA and VPA (MVPA) did not change significantly. Surprisingly, lockdown reduced the duration of sleep for older women but increased their amount of intense VPA (>6 METs). However, the amount of intense VPA decreased for men. Both genders reported overeating less during the pandemic than before it, but did not start consuming more alcohol, and their body mass index did not change. Thus, the COVID-19 in Lithuania represented ‘good stress’ that mobilized these individuals to exercise more independently and overeat less.

Download Full-text

Trends in leisure time physical activity, smoking, body mass index and alcohol consumption in Danish adults with and without diabetes: A repeat cross-sectional national survey covering the years 2000 to 2010

Diabetes Research and Clinical Practice ◽

10.1016/j.diabres.2014.05.009 ◽

2014 ◽

Vol 105 (2) ◽

pp. 217-222 ◽

Cited By ~ 13

Author(s):

Stig Molsted ◽

Nina Føns Johnsen ◽

Ole Snorgaard

Keyword(s):

Physical Activity ◽

Body Mass Index ◽

Alcohol Consumption ◽

Body Mass ◽

National Survey ◽

Leisure Time ◽

Leisure Time Physical Activity ◽

Cross Sectional

Download Full-text

Smoking and Heberden Nodes: Analysis of Data from the Osteoarthritis Initiative

Advances in Epidemiology ◽

10.1155/2016/2083683 ◽

2016 ◽

Vol 2016 ◽

pp. 1-7

Author(s):

R. Constance Wiener ◽

Alcinda K. Trickett Shockey

Keyword(s):

Age Groups ◽

Secondary Data ◽

Hand Osteoarthritis ◽

Dental Hygienists ◽

Chi Square ◽

Cross Sectional ◽

Current Smoking ◽

Osteoarthritis Initiative ◽

Distal Interphalangeal ◽

Logistic Regressions

Purpose. Dental hygienists, dentists, and other workforce providers who depend upon their hands for employment are acutely aware of the need to protect their hands to ensure a successful career. Recent research has suggested that smoking may be protective of hand osteoarthritis. The purpose of this study is to determine the association between smoking and Heberden’s nodes. Methods. Data from the Osteoarthritis Initiative were used in a cross-sectional, secondary data analysis of self-reported current smoking/never smoking and the presence/absence of Heberden’s nodes, the hard enlargements of the joints nearest the fingertips (distal interphalangeal joints). Analyses included descriptive statistics, Chi-square associations with Heberden’s nodes, and logistic regressions. Results. In adjusted analysis, smoking had an adjusted odds ratio for Heberden’s nodes of 0.832 [95% confidence interval: 0.60, 1.14] which failed to reach significance (P=.2488). In the selected model, females were more likely than males to have Heberden’s nodes; non-Hispanic Blacks were less likely than non-Hispanic Whites to have Heberden’s nodes; and older age groups were more likely than the youngest age group to have Heberden’s nodes. Conclusion. Smoking did not provide protection against Heberden’s nodes in this study of US participants in the Osteoarthritis Initiative.

Download Full-text