Chemical Profiling, Phytochemical Constituents and in vitro Antioxidant Activities of Ethanol Leaf Extract of Talinum triangulare

2021 ◽  
Vol 13 (1) ◽  
pp. 26-34
Author(s):  
Johnson O. Oladele ◽  
Boyede D. Olowookere ◽  
Mutiat O. Bamigboye ◽  
Oyedotun M. Oyeleke ◽  
Kehinde E. Alabi ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Antioxidant Activities ◽  
Chemical Profiling ◽  
Phytochemical Constituents ◽  
Talinum Triangulare

scholarly journals Evaluation of Pterospermum suberifolium L. Willd Leaves for the Phytochemical Constituents and their in vitro Activities

2020 ◽  
Vol 11 (3) ◽  
pp. 547-553
Author(s):  
Baskar Mohan ◽  
Vadamalai Krishnan K ◽  
Muthuraman K
Keyword(s):  
Leaf Extract ◽  
Antioxidant Activities ◽  
Quantitative Estimation ◽  
Antimicrobial Properties ◽  
Dpph Assay ◽  
Aqueous Methanol ◽  
Leaf Extracts ◽  
High Antioxidant Activity ◽  
Phytochemical Constituents

The present study was intended to investigate the phytochemical constituents present in the leaves of Pterospermum suberifolium L. WILLD and the in vitro  antioxidant and antimicrobial properties of the various extracts prepared by different solvents including aqueous, methanol, ethyl acetate and hexane. The crude extracts were screened for the presence of various phytochemical constituents and the presence of phenols, tannins, flavonoids, saponins and alkaloids were ascertained. The quantitative estimation of phenols and flavonoids were determined. The antioxidant activities of the plant leaf extracts were determined by the DPPH assay, the Phosphomolybdenum assay and the Nitric oxide scavenging assay. It was found that methanolic leaf extract of P. suberifolium possessed high antioxidant activity and found to have potential phytochemical constituents. 

Aqueous extracts of avocado pear (Persea americana Mill.) leaves and seeds exhibit anti-cholinesterases and antioxidant activities in vitro

2016 ◽  
Vol 27 (2) ◽  
Author(s):  
Ganiyu Oboh ◽  
Veronica O. Odubanjo ◽  
Fatai Bello ◽  
Ayokunle O. Ademosun ◽  
Sunday I. Oyeleye ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Inhibitory Effect ◽  
Seed Extract ◽  
Persea Americana ◽  
Dependent Manner ◽  
Natural Treatment

AbstractAvocado pear (The inhibitory effects of extracts on AChE and BChE activities and antioxidant potentials (inhibition of FeThe extracts inhibited AChE and BChE activities and prooxidant-induced TBARS production in a dose-dependent manner, with the seed extract having the highest inhibitory effect and the leaf extract exhibiting higher phenolic content and radical scavenging abilities, but lower Fe chelation ability compared with that of the seed. The phytochemical screening revealed the presence of saponins, alkaloids, and terpenoids in both extracts, whereas the total alkaloid profile was higher in the seed extract than in the leaf extract, as revealed by GC-FID.The anti-cholinesterase and antioxidant activities of avocado leaf and seed could be linked to their phytoconstituents and might be the possible mechanisms underlying their use as a cheap and natural treatment/management of AD. However, these extracts should be further investigated in vivo.

scholarly journals Evaluation of Antioxidant Properties ofPhaulopsis fascisepalaC.B.Cl. (Acanthaceae)

2009 ◽  
Vol 6 (2) ◽  
pp. 227-231 ◽  
Author(s):  
S. A. Adesegun ◽  
A. Fajana ◽  
C. I. Orabueze ◽  
H. A. B. Coker
Keyword(s):  
Ascorbic Acid ◽  
Leaf Extract ◽  
Antioxidant Activities ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Total Phenolic ◽  
Chelating Ability

The antioxidant activities of crude extract ofPhaulopsis fascisepalaleaf were evaluated and compared with α-tocopherol and BHT as synthetic antioxidants and ascorbic acid as natural-based antioxidant.In vitro, we studied its antioxidative activities, radical-scavenging effects, Fe2+-chelating ability and reducing power. The total phenolic content was determined and expressed in gallic acid equivalent. The extract showed variable activities in all of thesein vitrotests. The antioxidant effect ofP. fascisepalawas strongly dose dependent, increased with increasing leaf extract dose and then leveled off with further increase in extract dose. Compared to other antioxidants used in the study, α-Tocopherol, ascorbic acid and BHT,P. fascisepalaleaf extract showed less scavenging effect on α,α,-diphenyl-β-picrylhydrazyl (DPPH) radical and less reducing power on Fe3+/ferricyanide complex but better Fe2+-chelating ability. These results revealed thein vitroantioxidant activity ofP.fascisepala.Further investigations are necessary to verify these activitiesin vivo.

scholarly journals Assessment of in vitro Antioxidant and Antidiabetic Capacities of Medlar (Mespilus germanica)

2018 ◽  
Vol 47 (2) ◽  
pp. 384-389
Author(s):  
Sebnem Selen ISBILIR ◽  
Sevilay Inal KABALA ◽  
Hulya YAGAR
Keyword(s):  
Antioxidant Activity ◽  
Leaf Extract ◽  
Antioxidant Activities ◽  
Inhibitory Effect ◽  
Total Phenolic ◽  
Flower Bud ◽  
Ethanol Extracts ◽  
Dpph Scavenging ◽  
Β Carotene

The objective of the current study was to evaluate the antioxidant activity and enzyme inhibitory effect of different parts of medlar including fruit, leaf and flower bud by using various in vitro methods, and also determination of total phenolic and flavonoid content in the samples. Ethanol extracts of medlar parts were prepared and their antioxidant activities were determined using 1,1-diphenyl-2-picryl-hydrazil (DPPH•) scavenging and β-carotene bleaching methods. The leaf extract showed the strongest antioxidant activity. DPPHradical scavenging activity was in the order of BHA > leaf > bud > fruit. This ordering was the same for β-carotene bleaching activity, tocopherol > leaf > bud > fruit. The highest total phenolic (60.3 ± 1.69 mg GAE g-1 extract) and flavonoid (14.77 ± 1.15 mg QE g-1 extract) content were determined in leaf extract. For possible antidiabetic effects of extracts, α-amylase and α-glucosidase inhibitory activities were investigated, the bud extract showed the highest inhibition activities among the all extracts.

scholarly journals Green Synthesis, Characterization and In-vitro Antioxidant Property of Silver Nanoparticles Using the Aqueous Leaf Extract of Justicia carnea

2021 ◽  
pp. 20-30
Author(s):  
I. O. Salaudeen ◽  
M. O. Olajuwon ◽  
A. B. Ajala ◽  
T. O. Abdulkareem ◽  
S. A. Adeniyi ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Silver Nanoparticles ◽  
Leaf Extract ◽  
Antioxidant Activities ◽  
Silver Ions ◽  
Antioxidant Property ◽  
Biological Macromolecules ◽  
Aqueous Leaf Extract ◽  
In Vitro Antioxidant Activity

This study investigated the synthesis, characterization and in vitro antioxidant activity of silver nanoparticles (AgNPs) using the aqueous leaf extract of Justicia carnea.  The aqueous leaf extract of J. carnea was used as a potential reducing and capping agent. To identify the compounds responsible for the reduction of silver ions, the functional groups present in the plant extract were subjected to FTIR. The in vitro antioxidant activity of synthesized nanoparticles was evaluated in terms of ferric reducing antioxidant potential (FRAP), DPPH (1,1-diphenyl-2-picrylhydrazyl) and ABTS (2,2`-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) free radicals scavenging assays. The surface plasmon resonance confirmed the formation of AgNPs with maximum absorbance at kmax = 446 nm. FTIR revealed the biological macromolecules of J. carnea leaf extract involved in the synthesis and stabilization of AgNPs. UV-Visible spectrophotometer showed absorbance peak in the range of 436-446 nm. The silver nanoparticles exhibited moderate antioxidant activities compared to standard antioxidants (ascorbic acid and BHT). These results confirmed this protocol as simple, eco-friendly, nontoxic and an alternative for conventional physical and chemical methods. It can be concluded that J. carnea leaf extract can be used effectively in the production of potential antioxidant AgNPs which could be useful in various bio-applications such as cosmetics, food and biomedical industry.

scholarly journals Antioxidant Activities of the Leaf Extract and Fractions of Dryopteris filix-mas (L.) Schott could be Attributed to The Abundance of Polyphenol Compounds

2020 ◽  
Vol 9 (1) ◽  
pp. 1-6
Author(s):  
Earnest Oghenesuvwe Erhirhie ◽  
Emmanuel Emeka Ilodigwe ◽  
Daniel Lotanna Ajaghaku ◽  
Blessing Ogechukwu Umeokoli ◽  
Peter Maduabuchi Eze ◽  
...  
Keyword(s):  
Ethyl Acetate ◽  
Leaf Extract ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Bioactive Compound ◽  
Ethyl Acetate Fraction ◽  
In Vitro Assays ◽  
Anti Oxidant

Dryopteris filix mas (D filix-mas) is wildly used in ethnomedicine for the management of rheumatoid arthritis, wounds and other diseases. We investigated the anti-oxidant activities of its leaf extract, and chromatographic fractions. The ethanol leaf extract was partitioned into four fractions; n-hexane, ethyl acetate, n-butanol and water. Ferric reducing anti-oxidant power (FRAP), 1, 1-diphenyl-2-picrylhydrazil (DPPH) and nitric oxide (NO) scavenging in vitro assays were carried out on the extract and fractions at 6.25, 12.5, 25, 50, 100, 200, 400 and 800 µg/mL. The most active fraction (ethyl acetate fraction) was further purified using chromatographic techniques to isolate its major compound whose structure was elucidated using ID nuclear magnetic resonance (NMR) and mass spectrometry. The ethyl acetate fraction produced the highest free radical scavenging activity among the other fractions. The fraction (VLC-E7) from which the bioactive compound, quercetin-3-O-αL-rhamnopyranoside, was isolated had the best FRAP and DPPH scavenging activities with EC50 and IC50 values of 88.81 ± 3.41 and 26.87 ± 0.24 respectively more than the ethyl acetate fraction. This study revealed that the polyphenol flavonoid, quercetin-3-O-αL-rhamnopyranoside could be responsible for antioxidant activity of ethno-medicinal property of D filix-mas leaf.

scholarly journals IN VITRO ANTIOXIDANT AND ANTIHYPERGLYCEMIC ACTIVITIES OF HYDROETHANOLIC LEAF EXTRACT OF ACACIA CATECHU (L.F) WILLD

2017 ◽  
Vol 10 (11) ◽  
pp. 190
Author(s):  
Ramesh Balu ◽  
Jayabharathi V
Keyword(s):  
Leaf Extract ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Pharmaceutical Preparations ◽  
Maximum Activity ◽  
Increase With Increase ◽  
Nitric Oxide Radical ◽  
Acacia Catechu

  Objective: The aim of this study was to analyze the antioxidant and antihyperglycemic activities of hydroethanolic leaf extract of Acacia catechu (L.f) Willd. Methods: The A. catechu (L.f) Willd. leaf extract was subjected to antioxidant activities such as 1,1-diphenyl-1-picryl hydrazyl (DPPH), hydroxyl radical (OH−), nitric oxide radical (NO−), and superoxide radical (SO) scavenging assays. Further, the leaf extract was subjected to antihyperglycemic activity by α-amylase inhibition assay.Results: The free radical scavenging activity of the plant extract was found to increase with increase in concentration (20-100 μg/ml) and the maximum activity was obtained at 100 μg/ml, which was compared with the standard ascorbic acid. The percentage inhibition of free radicals was found to be 62.94±0.91%, 63.53±1.08%, 71.04±0.48%, and 51.50±0.86% for DPPH, OH−, NO−, and SO−, respectively. The IC50 for DPPH, OH−, NO−, and SO were recorded as 73.81±0.95, 69.03±0.58, 60.74±0.37, and 83.10±1.00 μg/ml. The IC50 value of α-amylase inhibitory activity was found to be 71.17 μg/ml.Conclusion: The present investigations suggest that the A. catechu (L.f) Willd may serve as a potential source of natural antioxidant and antihyperglycemic agent that could have great importance in pharmaceutical preparations. 

In-vitro catalytic, antimicrobial and antioxidant activities of bioengineered copper quantum dots using Mangifera indica (L.) leaf extract

2020 ◽  
Vol 239 ◽  
pp. 122052 ◽  
Author(s):  
Humaira Rani ◽  
Satarudra Prakash Singh ◽  
Thakur Prasad Yadav ◽  
Mohd Sajid Khan ◽  
Mohammad Israil Ansari ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Leaf Extract ◽  
Antioxidant Activities ◽  
Mangifera Indica

Folklore use of Osbeckia species from Munnar hills, Kerala

2018 ◽  
Vol 5 (2) ◽  
Author(s):  
Bosco Lawarence
Keyword(s):  
Antioxidant Activities ◽  
Herbal Remedies ◽  
Pharmacological Activities ◽  
Comprehensive Information ◽  
Carl Linnaeus ◽  
Anthocyanin Profile ◽  
Human Disorders ◽  
Phytochemical Constituents ◽  
Ethnomedicinal Uses

The genus Osbeckia of Melastomataceae was named by Carl Linnaeus, for the Swedish explorer and naturalist Pehr Osbeck. Osbeckias are native to Eastern Asia and found in China, Japan, Malaysia, India, Sri Lanka and Australasia. Most species were documented as herbal remedies for curing many human diseases. In India the genus comprises about 22 species out of which 12 species are reported from Kerala. Most of the species are small shrubs and have gained medicinal status in folklore belief from India, China, and Indonesia. Ethnopharmacologically, the leaves, shoots, barks, seeds, and roots of Melastomataceae members have been used to treat diarrhea, dysentery, hemorrhoids, cuts and wounds, toothache, and stomachache. The coloured floral extracts of various genera also revealed wide pharmacological actions such as anti-nociceptive, anti-in?ammatory, wound healing, antidiarrhoeal, cytotoxic, and antioxidant activities. Many phytochemical constituents including anthocyanins were isolated and identified from different parts of Melastoma and Memycylon species. Thus, the aim of this survey is to present comprehensive information on ethnomedicinal uses and pharmacological activities of Osbeckia species from Kerala. Floral extracts of most of the Osbeckia species contain substantial levels of phenols and anthocyanin. This data validate the folklore use of various species to cure many human disorders. Future studies are planned to evaluate the biological potentialities in terms of anthocyanin profile using in vitro cultures of the species such as O. aspera and O. reticulata.

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