Folklore use of Osbeckia species from Munnar hills, Kerala

2018 ◽  
Vol 5 (2) ◽  
Author(s):  
Bosco Lawarence
Keyword(s):  
Antioxidant Activities ◽  
Herbal Remedies ◽  
Pharmacological Activities ◽  
Comprehensive Information ◽  
Carl Linnaeus ◽  
Anthocyanin Profile ◽  
Human Disorders ◽  
Phytochemical Constituents ◽  
Ethnomedicinal Uses

The genus Osbeckia of Melastomataceae was named by Carl Linnaeus, for the Swedish explorer and naturalist Pehr Osbeck. Osbeckias are native to Eastern Asia and found in China, Japan, Malaysia, India, Sri Lanka and Australasia. Most species were documented as herbal remedies for curing many human diseases. In India the genus comprises about 22 species out of which 12 species are reported from Kerala. Most of the species are small shrubs and have gained medicinal status in folklore belief from India, China, and Indonesia. Ethnopharmacologically, the leaves, shoots, barks, seeds, and roots of Melastomataceae members have been used to treat diarrhea, dysentery, hemorrhoids, cuts and wounds, toothache, and stomachache. The coloured floral extracts of various genera also revealed wide pharmacological actions such as anti-nociceptive, anti-in?ammatory, wound healing, antidiarrhoeal, cytotoxic, and antioxidant activities. Many phytochemical constituents including anthocyanins were isolated and identified from different parts of Melastoma and Memycylon species. Thus, the aim of this survey is to present comprehensive information on ethnomedicinal uses and pharmacological activities of Osbeckia species from Kerala. Floral extracts of most of the Osbeckia species contain substantial levels of phenols and anthocyanin. This data validate the folklore use of various species to cure many human disorders. Future studies are planned to evaluate the biological potentialities in terms of anthocyanin profile using in vitro cultures of the species such as O. aspera and O. reticulata.

scholarly journals Melastoma malabathricum(L.) Smith Ethnomedicinal Uses, Chemical Constituents, and Pharmacological Properties: A Review

2012 ◽  
Vol 2012 ◽  
pp. 1-48 ◽  
Author(s):  
S. Mohd. Joffry ◽  
N. J. Yob ◽  
M. S. Rofiee ◽  
M. M. R. Meor Mohd. Affandi ◽  
Z. Suhaili ◽  
...  
Keyword(s):  
Pacific Islands ◽  
Antioxidant Activities ◽  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Melastoma Malabathricum ◽  
Comprehensive Information ◽  
The Pacific ◽  
Phytochemical Constituents ◽  
Temperate Asia ◽  
Ethnomedicinal Uses

Melastoma malabathricumL. (Melastomataceae) is one of the 22 species found in the Southeast Asian region, including Malaysia. Considered as native to tropical and temperate Asia and the Pacific Islands, this commonly found small shrub has gained herbal status in the Malay folklore belief as well as the Indian, Chinese, and Indonesian folk medicines. Ethnopharmacologically, the leaves, shoots, barks, seeds, and roots ofM. malabathricumhave been used to treat diarrhoea, dysentery, hemorrhoids, cuts and wounds, toothache, and stomachache. Scientific findings also revealed the wide pharmacological actions of various parts ofM. malabthricum, such as antinociceptive, anti-inflammatory, wound healing, antidiarrheal, cytotoxic, and antioxidant activities. Various types of phytochemical constituents have also been isolated and identifed from different parts ofM. malabathricum. Thus, the aim of the present review is to present comprehensive information on ethnomedicinal uses, phytochemical constituents, and pharmacological activities ofM. malabathricum.

scholarly journals FivePistaciaspecies (P. vera,P. atlantica,P. terebinthus,P. khinjuk, andP. lentiscus): A Review of Their Traditional Uses, Phytochemistry, and Pharmacology

2013 ◽  
Vol 2013 ◽  
pp. 1-33 ◽  
Author(s):  
Mahbubeh Bozorgi ◽  
Zahra Memariani ◽  
Masumeh Mobli ◽  
Mohammad Hossein Salehi Surmaghi ◽  
Mohammad Reza Shams-Ardekani ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Flowering Plants ◽  
Gastrointestinal Disorders ◽  
Pharmacological Activities ◽  
Beneficial Effects ◽  
Comprehensive Information ◽  
The Family ◽  
Phytochemical Constituents ◽  
Ethnomedicinal Uses ◽  
Different Parts

Pistacia, a genus of flowering plants from the family Anacardiaceae, contains about twenty species, among them five are more popular includingP. vera, P. atlantica, P. terebinthus, P. khinjuk,andP. lentiscus. Different parts of these species have been used in traditional medicine for various purposes like tonic, aphrodisiac, antiseptic, antihypertensive and management of dental, gastrointestinal, liver, urinary tract, and respiratory tract disorders. Scientific findings also revealed the wide pharmacological activities from various parts of these species, such as antioxidant, antimicrobial, antiviral, anticholinesterase, anti-inflammatory, antinociceptive, antidiabetic, antitumor, antihyperlipidemic, antiatherosclerotic, and hepatoprotective activities and also their beneficial effects in gastrointestinal disorders. Various types of phytochemical constituents like terpenoids, phenolic compounds, fatty acids, and sterols have also been isolated and identified from different parts ofPistaciaspecies. The present review summarizes comprehensive information concerning ethnomedicinal uses, phytochemistry, and pharmacological activities of the five mentionedPistaciaspecies.

Ethnomedicinal uses, Phytochemistry and Pharmacological Aspects of the Genus Berberis Linn: A Comprehensive Review

2020 ◽  
Vol 23 ◽  
Author(s):  
Roohi Mohi-ud-din ◽  
Reyaz Hassan Mir ◽  
Prince Ahad Mir ◽  
Saeema Farooq ◽  
Syed Naiem Raza ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Traditional Use ◽  
Comprehensive Review ◽  
Wide Range ◽  
Anti Cancer ◽  
Comprehensive Survey ◽  
Ethnomedicinal Uses

Background: Genus Berberis (family Berberidaceae), which contains about 650 species and 17 genera worldwide, has been used in folklore and various traditional medicine systems. Berberis Linn. is the most established group among genera with around 450-500 species across the world. This comprehensive review will not only help researchers for further evaluation but also provide substantial information for future exploitation of species to develop novel herbal formulations. Objective: The present review is focussed to summarize and collect the updated review of information of Genus Berberis species reported to date regarding their ethnomedicinal information, chemical constituents, traditional/folklore use, and reported pharmacological activities on more than 40 species of Berberis. Conclusion: A comprehensive survey of the literature reveals that various species of the genus possess various phytoconstituents mainly alkaloids, flavonoid based compounds isolated from different parts of a plant with a wide range of pharmacological activities. So far, many pharmacological activities like anti-cancer, anti-hyperlipidemic, hepatoprotective, immunomodulatory, anti-inflammatory both in vitro & in vivo and clinical study of different extracts/isolated compounds of different species of Berberis have been reported, proving their importance as a medicinal plant and claiming their traditional use.

scholarly journals PHYTOCHEMICAL CONSTITUENTS AND PHARMACOLOGICAL ACTIVITIES OF Kigelia africana AND Mansoa alliacea - A COMPREHENSIVE REVIEW

2018 ◽  
Vol 11 ◽  
Author(s):  
Sowmyalakshmi Venkataraman ◽  
Gunda Srilakshmi
Keyword(s):  
Rural Areas ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Reproductive Organ ◽  
Human Beings ◽  
Pharmacological Activities ◽  
Phytochemical Constituents ◽  
Athlete’S Foot ◽  
Collective Information

Context: The focus of the present review is to compile the different phytochemical constituents and pharmacological activities of bignoniaceous plants, namely Kigelia africana and Mansoa alliacea. Objective: Medicinal plants are routinely used in clinical practice for the treatment of various diseases of human beings over thousands of years across the world. In rural areas of the developing countries, they are still used in practice due to the easy availability of the medication. The main objective of this work is to explore the phytochemical studies and biological activities of plants belonging to Bignoniaceae family. Methods: The present study also discusses about the different phytochemical constituents of K. africana and M. alliacea that were isolated and characterized using various analytical methods. Different extracts of these plants were subjected to different in vitro anticancer, analgesic, antimicrobial, and antimalarial activities using earlier reported methods were also discussed. Results: K. africana is commonly referred to as sausage or cucumber tree due to its huge sausage or cucumber-like fruit. These plants find application as traditional medicine for treating several ailments such as malignant tumor, ulcer, aging, and malaria among others. It is conjointly used for the treatment of reproductive organ infections, renal ailments, dizziness, epilepsy, sickle cell disease, depression, metabolism disorders, skin grievance, leprosy, impetigo, helminthic infections, athlete’s foot, tumors, etc. These plant extracts have also been used as a cosmetic by enhancing the collagen action and thus exhibit antiaging properties. Conclusion: The present study attempts to provide collective information on various phytochemical constituents and pharmacological actions of K. africana and M. alliacea belonging to Bignoniaceae. This review in its present form is believed to help the researchers to provide adequate information about the chemical constituents and biological uses of these plants.

scholarly journals Traditional uses, phytochemistry, and pharmacological activities of Cochlospermum tinctorium A. Rich (Cochlospermaceae): a review

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Mubarak Hussaini Ahmad ◽  
Abubakar Ibrahim Jatau ◽  
Garba M. Khalid ◽  
Omar Yahya Alshargi
Keyword(s):  
Liver Diseases ◽  
Bioactive Molecules ◽  
Pharmacological Activities ◽  
Main Text ◽  
Traditional Uses ◽  
Comprehensive Information ◽  
The Family ◽  
Arjunolic Acid ◽  
Ethnomedicinal Uses ◽  
Different Parts

Abstract Background The plant Cochlospermum tinctorium A. Rich is a sub-shrub that belongs to the family Cochlospermaceae. The plant has been used in traditional medicine for the treatment of malaria, rickets, stomachache, diarrhea, gastric ulcer, parasitic infestations, liver diseases, fever, pain, inflammation, infectious diseases, epilepsy, snake bite, burns, orchitis, labour, menstrual problems, and many other diseases. This review summarizes the traditional uses, phytochemistry, and pharmacological activities of Cochlospermum tinctorium. Main text To date, few bioactive molecules have been identified and isolated from the plant such as 7,3-dimethyldihydroquercelin, 5,4-dimethylquercelin, cochloxanthine, dihydrocochloxanthine, arjunolic acid, 3-O-E-p-coumaroylalphitolic acid, alphitolic acid, 1-hydroxytetradecan-3-one, 3-bisabolen, 2-tridecanone, 3-hexadecanone, 1-dodecanol, l-tetradecanol, 2-pentdecanone, 3-octadecanone, 1-hydroxy-3-hexadecanone, 1-nonadecanol, l-O-acetyl-3-hexadecanone, and l-hydroxy-3-oetadecanone. The literature related some of the reported ethnomedicinal uses of the plant to these compounds found in the different parts of the plant. Conclusion The comprehensive information documented in this review about the importance of the C. tinctorium may provide an opportunity for research advancement in drug discovery and a better understanding of the medicinal benefits of the plant.

Chemical Profiling, Phytochemical Constituents and in vitro Antioxidant Activities of Ethanol Leaf Extract of Talinum triangulare

2021 ◽  
Vol 13 (1) ◽  
pp. 26-34
Author(s):  
Johnson O. Oladele ◽  
Boyede D. Olowookere ◽  
Mutiat O. Bamigboye ◽  
Oyedotun M. Oyeleke ◽  
Kehinde E. Alabi ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Antioxidant Activities ◽  
Chemical Profiling ◽  
Phytochemical Constituents ◽  
Talinum Triangulare

Phytochemical Constituents of Guggul and their Biological Qualities

2020 ◽  
Vol 17 (3) ◽  
pp. 277-288 ◽  
Author(s):  
Vijay Kumar ◽  
Simranjeet Singh ◽  
Ravindra Singh
Keyword(s):  
Pharmacological Activities ◽  
Commiphora Wightii ◽  
Toxicological Studies ◽  
Wide Range ◽  
Commiphora Mukul ◽  
Medicinal Properties ◽  
Phytochemical Constituents ◽  
Herbal Formulations

: In the herbal drug pharmaceutical industry, guggul is enjoying emergent consumer acceptance around the world. In the Indian market, more than fifty formulations of guggul have been introduced by well-known brands including Himalaya, Patanjali and Baidyanath Pharmaceuticals. Basically, guggul is the gum resin from Commiphora wightii (syn. Commiphora Mukul). It has been used to treat various ailments including obesity, osteoarthritis, arthritis, constipation, liver disorders, inflammation, anemia, diabetes, etc. Including medicinal properties, it is used as a good binding agent and mixed in various herbal formulations. To review the major phytochemical, medicinal properties and analytical methods involved in the detection of guggul by using the exhaustive bibliographic research by means of various scientific engines and databases. Guggul contained approximately 66 phytochemical including gallic acid, quercetin, and guggulsterones E and Z. These phytochemicals have a wide range of pharmacological activities such as antioxidant, antibacterial, antimutagenic, antivenom and antitumor. It has been noticed that the mode of action of guggulsterone has not been fully explored. Pharmacology and toxicological studies are very few. These works have shown huge literature gap, which is to be fulfilled through the detailed in-vivo and in-vitro studies.

scholarly journals Antioxidant and Anti-Inflammatory Properties of a Thuja occidentalis Mother Tincture for the Treatment of Ulcerative Colitis

Antioxidants ◽  
2019 ◽  
Vol 8 (9) ◽  
pp. 416 ◽  
Author(s):  
Miruna Silvia Stan ◽  
Sorina Nicoleta Voicu ◽  
Sonia Caruntu ◽  
Ionela Cristina Nica ◽  
Neli-Kinga Olah ◽  
...  
Keyword(s):  
Antioxidant Activities ◽  
Herbal Remedies ◽  
Capacity Measurement ◽  
Trinitrobenzenesulfonic Acid ◽  
Colon Cells ◽  
Thuja Occidentalis ◽  
Anti Inflammatory ◽  
Mother Tincture

Inflammatory bowel disease (IBD) represents a group of chronic autoimmune and idiopathic disorders that are characteristic of industrialized countries. In contrast to drug therapies, which exert several side effects, herbal remedies have constantly attracted the attention of researchers. Therefore, in the present study, a mother tincture (MT) from fresh, young, non-woody Thuja occidentalis L. branches with leaves was obtained using distillation-based techniques. Further, this was used to assess its in vitro and in vivo antioxidant activities and anti-inflammatory properties, and to validate it as a potential phytotherapeutic treatment for IBD. The characterization of the tincture included common phytochemical screening assays for antioxidant capacity measurement, cell viability assays on Caco-2 colon cells, and in vivo assessment of antioxidant and anti-inflammatory effects by histopathological and ultrastructural analysis of the intestinal mucosa, measurement of reduced glutathione, lipid peroxidation, and gene expression of the inflammation markers (interleukin-6 and tumor necrosis factor-α) in intestine after oral administration to an experimental mouse model of colon inflammation (colitis) developed by intrarectal administration of 2,4,6-trinitrobenzenesulfonic acid (TNBS). Our study proved that administration of 25 or 50 mg T. occidentalis MT/kg of body weight/day by gavage for 7 days succeeded in inhibiting the inflammatory process induced by TNBS in the intestine, most probably because of its rich contents of flavonoids and phenolic compounds. These data could contribute to the formulation of therapeutic products based on T. occidentalis that could come to the aid of IBD patients.

scholarly journals A Narrative Review on the Phytochemistry, Pharmacology and Therapeutic Potentials of Clinacanthus nutans (Burm. f.) Lindau Leaves as an Alternative Source of Future Medicine

Molecules ◽  
2021 ◽  
Vol 27 (1) ◽  
pp. 139
Author(s):  
Tan Yong Chia ◽  
Chee Yuen Gan ◽  
Vikneswaran Murugaiyah ◽  
Syed F. Hashmi ◽  
Tabinda Fatima ◽  
...  
Keyword(s):  
Antioxidant Activities ◽  
Well Being ◽  
Renal Diseases ◽  
Pharmacological Activities ◽  
Alternative Source ◽  
Medicinal Uses ◽  
Toxicological Studies ◽  
Clinacanthus Nutans

The application of natural products and supplements has expanded tremendously over the past few decades. Clinacanthus nutans (C. nutans), which is affiliated to the Acanthaceae family, has recently caught the interest of researchers from the countries of subtropical Asia due to its medicinal uses in alternative treatment for skin infection conditions due to insect bites, microorganism infections and cancer, as well as for health well-being. A number of bioactive compounds from this plant’s extract, namely phenolic compounds, sulphur containing compounds, sulphur containing glycosides compounds, terpens-tripenoids, terpens-phytosterols and chlorophyll-related compounds possess high antioxidant activities. This literature search yielded about one hundred articles which were then further documented, including the valuable data and findings obtained from all accessible electronic searches and library databases. The promising pharmacological activities from C. nutans leaves extract, including antioxidant, anti-cancer, anti-viral, anti-bacterial, anti-fungal, anti-venom, analgesic and anti-nociceptive properties were meticulously dissected. Moreover, the authors also discuss a few of the pharmacological aspect of C. nutans leaves extracts against anti-hyperlipidemia, vasorelaxation and renoprotective activities, which are seldom available from the previously discussed review papers. From the aspect of toxicological studies, controversial findings have been reported in both in-vitro and in-vivo experiments. Thus, further investigations on their phytochemical compounds and their mode of action showing pharmacological activities are required to fully grasp both traditional usage and their suitability for future drugs development. Data related to therapeutic activity and the constituents of C. nutans leaves were searched by using the search engines Google scholar, PubMed, Scopus and Science Direct, and accepting literature reported between 2010 to present. On the whole, this review paper compiles all the available contemporary data from this subtropical herb on its phytochemistry and pharmacological activities with a view towards garnering further interest in exploring its use in cardiovascular and renal diseases.

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