Nanotechnology based herbal formulations: A survey of recent patents, advancements and transformative headways

2021 ◽  
Vol 15 ◽  
Author(s):  
Anureet Kaur ◽  
Lakhvir Kaur ◽  
Gurjeet Singh ◽  
RK Dhawan ◽  
Ayushi Mahajan
Keyword(s):  
Side Effects ◽  
Herbal Medicine ◽  
Adverse Effects ◽  
Traditional Medicine ◽  
Synergistic Effects ◽  
Complete Information ◽  
Review Article ◽  
Innovative Technology ◽  
Herbal Drugs ◽  
Herbal Formulations

: Nanotechnology in association with the herbal medicine can lead to enhanced therapeutic and diminished adverse effects of medication. In turn, it can lead to synergistic effects of administered compound overcoming its demerits. Now-a-days, the trend of herbal compounds to treat even a small illness is gaining momentum. Gone are the days when the ineffectiveness of a compound was impossible to be dealt with. Nevertheless, in this competitive era of science and innovative technology, it has become possible to maximize the usefulness of ineffective yet potent herbal compounds. The demand of herbal compounds is getting amplified because of their ability to treat myriad of diseases including COVID-19, showing less side effects. The merger of nanotechnology with traditional medicine augments the potential of herbal drugs for devastating dangerous and chronic diseases like cancer. In this review article, we have tried to assimilate the complete information regarding the use of different nanocarriers to overcome the drawbacks of herbal compounds. In addition, all the recent advancements in the herbal field as well as the future exploration to be emphasized have been discussed.

Nano Phytomedicine Based Delivery System for CNS Disease

2020 ◽  
Vol 21 (9) ◽  
pp. 661-673 ◽  
Author(s):  
Mohammed Asadullah Jahangir ◽  
Chettupalli Anand ◽  
Abdul Muheem ◽  
Sadaf Jamal Gilani ◽  
Mohamad Taleuzzaman ◽  
...  
Keyword(s):  
Herbal Medicine ◽  
Low Cost ◽  
Herbal Medicines ◽  
Herbal Drugs ◽  
Widespread Acceptance ◽  
The Central Nervous System ◽  
Low Toxicity ◽  
Ancient Times ◽  
Plant Sources ◽  
Herbal Formulations

Herbal medicines are being used since ancient times and are an important part of the alternative and traditional medicinal system. In recent decades, scientists are embracing herbal medicines based on the fact that a number of drugs that are currently in use are derived directly or indirectly from plant sources. Moreover, herbal drugs have lesser side effects, albeit are potentially strong therapeutic agents. The herbal medicine market is estimated to be around US $62 billion globally. Herbal medicine has gained widespread acceptance due to its low toxicity, low cost, ease of accessibility and efficacy in treating difficult diseases. Safety and efficacy are another important factors in the commercialization process of herbal medicines. Nanotechnology has been shown to be potentially effective in improving the bioactivity and bioavailability of herbal medicines. Development of nano-phytomedicines (or by reducing the size of phytomedicine), attaching polymers with phytomedicines and modifying the surface properties of herbal drugs, have increased the solubility, permeability and eventually the bioavailability of herbal formulations. Novel formulations such as niosomes, liposomes, nanospheres, phytosomes etc., can be exploited in this area. This article reviews herbal medicines, which have prominent activity in the Central Nervous System (CNS) disorders and reported nano-phytomedicines based delivery systems.

Herbal Drug Interactions

2017 ◽  
pp. 201-231 ◽  
Author(s):  
Mymoona Akhter
Keyword(s):  
Drug Interaction ◽  
Side Effects ◽  
Adverse Effects ◽  
Drug Interactions ◽  
Herbal Medicines ◽  
Herbal Drugs ◽  
Herbal Drug ◽  
Herbal Therapy ◽  
Alternative Medicines ◽  
Regulatory Bodies

Use of complementary and alternative medicines (CAM) for preventive and therapeutic purposes has increased tremendously in the last two decades internationally. The manufacturers of these products are not required to submit proof of safety or efficacy to the Food and Drug Administration. As a result, the adverse effects and drug interactions associated with them are largely unknown. In this chapter, the author presents interactions of herbal medicines with other medicines (herbal or non-herbal). A large number of herbal drugs, including from single drug to a variety of mixtures have been used to treat kidney disorders. Herb-herb or herb drug interaction has been reported intensively during last decade, therefore it becomes important to keep an eye on the use of combination herbal therapy in order to avoid serious results because of interactions with each other. Due to the growing awareness about the interactions and side effects of herbal drugs/supplements over the past few years, regulatory bodies are working on these issues and pharmacopoeias are being developed for reference.

scholarly journals The Combination of Lonicera japonica Thunb. and Other Herbs to Cure Common Diseases in Vietnam

2020 ◽  
Vol 11 (4) ◽  
pp. 6548-6552
Author(s):  
Huynh Tan Hoi
Keyword(s):  
Side Effects ◽  
Herbal Medicine ◽  
Traditional Medicine ◽  
Lonicera Japonica ◽  
Herbal Remedies ◽  
Oriental Medicine ◽  
Active Ingredients ◽  
Healing Effect ◽  
The Family ◽  
Support Treatment

Medicines from natural herbs are simple to use, easy to find, both with curative value while minimizing unwanted side effects. It's natural active ingredients help increase immunity, support treatment, and prevent diseases quite well. Knowing about these herbs will help us to take better care of ourselves and our loved ones. In current curative methods, traditional medicine methods are being trusted and used by many people because traditional medicine brings many health benefits, helps patients treat their diseases well and improve their health. The remedies from oriental medicine are derived from natural herbs, so they are very good for us. Surely everyone will know some types of plants in the family, in the garden, or just around the house such as ginger, lemongrass, etc. has an excellent healing effect. Therefore, the herbs available in nature can be turned into a cure without spending as much money as when using a Western medication. Currently, many patients are using natural herbal remedies for the highest effectiveness. In particular, many patients are suffering from dangerous and difficult to cure diseases who have sought to cure with traditional medicine and herbal medicine; they have seen better progress with these treatments. This paper mentions lonicera japonica Thunb as an excellent herb because of its effects, and by combining with other herbs successfully, these therapies can cure many diseases.

scholarly journals COVID-19 Vaccines in Pakistan: Efficacy, Adverse Effects and Availability

2021 ◽  
Vol 10 (2) ◽  
pp. 125-130
Author(s):  
Soma Siddique ◽  
Shaheer Ahmed
Keyword(s):  
Clinical Trials ◽  
Side Effects ◽  
Adverse Effects ◽  
Mode Of Action ◽  
Public Awareness ◽  
Grey Literature ◽  
Large Population ◽  
Review Article ◽  
Pain On Injection ◽  
The World

In this review article, we aim to document the efficacy, adverse effects, mode of action, required doses, and availability of the major vaccines available in Pakistan till 20 May 2021. We reviewed all available literature on COVID-19 vaccines in PubMed and Google scholar. We also reviewed articles from grey literature. Currently, Pfizer–BioNTech and Moderna, Sinopharm (China), Sputnik V (Russia), CoronaVac (popularly known as Sinovac) (China), Cansino, and Vaxzevria vaccines have been authorized for emergency use in several countries. Pakistan has sanctioned the use of all the aforementioned vaccines except Pfizer and Moderna. As per their efficacy, Pfizer and Moderna have been found most effective among all the vaccines with 95% effectiveness, while the Vaxzevria, Sputnik V, Sinopharm, and Cansino have shown 70%, 91.6%, 79.34%, and 90% effectiveness, respectively. All the vaccines have shown milder side effects like headache, fever, and pain on injection sites. To curb the pandemic, more clinical trials are being conducted throughout the world. Importantly public awareness is warranted to achieve the target of vaccinating a large population.

scholarly journals Perception of Conventional Medicine and Herbal Medicine Usage Amongst Diabetic Patients: A Qualitative Study in Negeri Sembilan, Malaysia

2020 ◽  
Vol 12 (10) ◽  
pp. 122
Author(s):  
Norbaidurah Ithnain ◽  
Albeny Joslyn Panting ◽  
Rosnani Kassim ◽  
Nadia Amirudin ◽  
Manimaran Krishnan
Keyword(s):  
Side Effects ◽  
Herbal Medicine ◽  
Qualitative Study ◽  
Adverse Effects ◽  
Conventional Medicine ◽  
Healthcare Providers ◽  
Diabetic Patients ◽  
Structured Interviews ◽  
Type 2 Diabetic Mellitus ◽  
Negative Side Effects

INTRODUCTION: The concomitant intake of herbal medicine and conventional medicine amongst patients is steadily increasing worldwide. However, concerns have been raised regarding potential adverse effects and drug interactions when consuming both medications together. Therefore, this work aimed to comprehending the perception of Type 2 Diabetic Mellitus (T2DM) patients on conventional medicine and the manner of its use with herbal medicine in managing diabetes mellitus. METHODS: A qualitative study was conducted among 28 diabetic patients in four government clinics under the jurisdiction of the state of Negeri Sembilan, Malaysia. Purposive sampling was employed to recruit informants who consumed herbal medicine alongside their prescribed conventional medicine. This study employed semi-structured interviews, which were all digitally recorded, transcribed, and analysed thematically. RESULTS: This study found that most of the patients perceived the negative side effects of conventional medicine, which led them to consider incorporating herbal medicine in treating diabetes. Such perception was influenced by the personal experiences of their family members and friends. A majority of the informants utilised herbal medicine as a complementary consumption to conventional medicine as opposed to implementing it as an alternative. However, they would alter the dosage and intake time of conventional medicine for several reasons, such as to complement their herbal medicine intake, being fed-up with conventional medicine, and reduce the risk of its side effects. Lastly, this study revealed that some of the patients noted their intention to discontinue conventional medicine, while some even tried to quit. CONCLUSIONS: A complete understanding of patient’s perceptions regarding conventional medicine and its usage with herbal medicine will aid healthcare providers to deliver education on the importance of conventional medicine usage compliance. Additionally, people should be aware that its combination with herbal medicine when consumed may present adverse effects and subsequently cause serious health problems.

Investigating the relation between anti-oxidant activity and epileptic enzymes of formulation-40 capsules

2020 ◽  
Vol 4 (1) ◽  
pp. 6-9
Author(s):  
Bhavani J ◽  
Ravichandran S
Keyword(s):  
Side Effects ◽  
Adverse Effects ◽  
Chemical Constituents ◽  
Standard Drug ◽  
Protective Enzyme ◽  
Anti Oxidant ◽  
Dose Dependent ◽  
The Brain ◽  
Herbal Formulations ◽  
Human Nervous System

Seizures and Epilepsy are those major conditions that are common symptoms of many diseases that affect the human nervous system. It is one of the most chronic and commonest of the neurological disorders that is prevalent in almost 5crore people around the world. Even though the drugs are effective and potent, there are various side effects and adverse effects are associated with those drugs. General side effects include the nausea and vomitings, many other specific side effects include altered mental consciousness, confusion anorexia and excessive aggression are also noted in many cases of drugs. In this research, herbal formulations were designed to fight back the free radicals that are generated in the brain and those protective enzyme levels were analyzed to estimate the activity of the formulation in the brain tissue. In the research, the prepared formulation showed a dose dependent activity in restoring the brain protective enzymes and balancing them. The formulation contained herb powders that contain antioxidant chemical constituents which helped for the anti-epileptic formulation. The herbal capsules at dose 500mg/kg showed a better activity compared to the standard drug but without notable side effects and adverse effects.

Stratagems of Nanotechnology Augmenting the Bioavailability and Therapeutic Efficacy of Traditional Medicine to Formulate Smart Herbal Drugs Combating

2017 ◽  
pp. 250-282
Author(s):  
Anita Margret
Keyword(s):  
Mental Health ◽  
Traditional Medicine ◽  
Herbal Medicines ◽  
Global Burden ◽  
Emotional States ◽  
Herbal Drugs ◽  
Active Components ◽  
Scientific Analysis ◽  
Mental Abilities ◽  
Herbal Formulations

Mental illness is one of the most fundamental emotional states of conscious being which becomes unbalanced and leads to neurological disorders. It is a significant contributor to the global burden of disease and there is a strong desire to devise a remedy. Ayurveda represents a traditional medicine system of India that endorses antiquity than western medicine and relies on formulations rather than their active components. It has categorised a group of herbal medicines to improve mental abilities. Conversely, the mechanistic details of the therapy are not available in ayurvedic literature and there is a need to fortify this system with modern scientific analysis. The design of nanosystems encompasses promising characteristics in the field of drug delivery with a limited dosage thereby decreasing adverse effects. This chapter confers stratagems of devising polymeric nano herbal formulations as smart nano brain drugs to espouse mental health.

Herbal Drug Interactions

2022 ◽  
pp. 120-141
Author(s):  
Mymoona Akhter
Keyword(s):  
Drug Interaction ◽  
Side Effects ◽  
Adverse Effects ◽  
Drug Interactions ◽  
Herbal Medicines ◽  
Herbal Drugs ◽  
Herbal Drug ◽  
Herbal Therapy ◽  
Alternative Medicines ◽  
Regulatory Bodies

Use of complementary and alternative medicines (CAM) for preventive and therapeutic purposes has increased tremendously in the last two decades internationally. The manufacturers of these products are not required to submit proof of safety or efficacy to the Food and Drug Administration. As a result, the adverse effects and drug interactions associated with them are largely unknown. In this chapter, the author presents interactions of herbal medicines with other medicines (herbal or non-herbal). A large number of herbal drugs, including from single drug to a variety of mixtures have been used to treat kidney disorders. Herb-herb or herb drug interaction has been reported intensively during last decade, therefore it becomes important to keep an eye on the use of combination herbal therapy in order to avoid serious results because of interactions with each other. Due to the growing awareness about the interactions and side effects of herbal drugs/supplements over the past few years, regulatory bodies are working on these issues and pharmacopoeias are being developed for reference.

scholarly journals Perilaku Penggunaan Obat Tradisional pada Ibu Nifas di Desa Sungai Kitano Kecamatan Martapura Timur Kabupaten Banjar

2019 ◽  
Vol 9 (2) ◽  
pp. 68
Author(s):  
Faizah Wardhina ◽  
Fakhriyah Fakhriyah ◽  
Rusdiana Rusdiana
Keyword(s):  
Side Effects ◽  
Herbal Medicine ◽  
Traditional Medicine ◽  
Total Population ◽  
Post Partum ◽  
Well Being ◽  
Medicine Use ◽  
Postpartum Mothers

ABSTRACT Introduction: Traditional Medicine is a natural ingredient which is well known and believed by people as a mild treatment used in maintenance of health and in the prevention of illnes and well being. People in in Sungai Kitano still utilize that culture, include traditional medicine for postpartum maternal. Aims: This study aimed to know about desciption of behaviour in using traditional medicine among post partum maternal at Sungai Kitano Village. Method: The study aimed to determine the behavior of traditional medicine use for postpartum mothers in the Sungai Kitano Village By using descriptive type of research, the sample in this study were mothers who were postpartum and who had postpartum not more than 3 years and lived in the Sungai Kitano Village. Sample are 48 peoples, using total population. Result: Postpartum maternal who use traditional medicine during the puerperal period as much as (95.83%), types of traditional medicine that are widely used: herbal medicine 37 people (77.08%), a rajangan form of traditional medicine that is widely used: 28 people (58, 33%), the most widely used by drinking 31 people (64.58%), the most reason for using traditional medicine because of the customs / habits of their parents are 28 people (62.5%),who feels the benefit are 46 people (95.83%),and who has no side effects: 42 people (86.95%). Conclusion:Post Partum maternal in Sungai Kitano Village mostly use traditional medicine in rajangan form, which is drank because of the customs / habits of their parents and had felt its benefit. Suggested for maternal who is using traditional medicine for paying attention in how to use, especially in the process of making in order to keep its cleaning.

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