Evaluating Graph Drawing Aesthetics

2011 ◽  
pp. 145-179 ◽  
Author(s):  
Helen C. Purchase
Keyword(s):  
Experimental Research ◽  
Computational Efficiency ◽  
Graph Drawing ◽  
Design Principles ◽  
Research Area ◽  
Graph Layout ◽  
Future Work

This chapter describes a long-term project that investigates the validity of the design principles — not from the perspective of computational efficiency, but from the perspective of human comprehension — upon which many automatic graph layout algorithms are based. It describes a framework for experimentation in this area, the overall methodology used throughout, as well as the details of the experiments themselves. It shows the development of the empirical ideas and methods as the project matured and provides reflections on each experiment, demonstrating the difficulty of initiating a new experimental research area. The chapter suggests how the current results should best be interpreted, as well as ideas for future work in this area.

The effects of long-term vigorous endurance exercise on the coronary arteries

2019 ◽  
Vol 67 (2) ◽  
Keyword(s):  
Endurance Training ◽  
Coronary Atherosclerosis ◽  
Calcium Score ◽  
The Other ◽  
Disease Phenotype ◽  
Male Athletes ◽  
Artery Disease ◽  
Future Work ◽  
Summary Data

Moderate endurance training is known to improve cardiovascular risk factors, and prolongs life expectancy. On the other hand, there has been some discussion whether “too much” exercise might have a contrarious effect by accelerating coronary atherosclerosis. The goal of this review was to evaluate the current literature on the effects of long-term vigorous endurance training on the coronary vasculature. In summary, data point to an increased calcium score, and a higher burden of atherosclerotic plaque in male athletes compared to sedentary controls. However, the plaques found in athletes were more prone to be calcified. The pathogenesis and clinical relevance of this athlete coronary artery disease phenotype remains incompletely understood and represents an area of important future work.

The effects of long-term vigorous endurance exercise on the coronary arteries

2019 ◽  
Vol 67 (2) ◽  
Keyword(s):  
Endurance Training ◽  
Coronary Atherosclerosis ◽  
Calcium Score ◽  
The Other ◽  
Disease Phenotype ◽  
Male Athletes ◽  
Artery Disease ◽  
Future Work ◽  
Summary Data

Moderate endurance training is known to improve cardiovascular risk factors, and prolongs life expectancy. On the other hand, there has been some discussion whether “too much” exercise might have a contrarious effect by accelerating coronary atherosclerosis. The goal of this review was to evaluate the current literature on the effects of long-term vigorous endurance training on the coronary vasculature. In summary, data point to an increased calcium score, and a higher burden of atherosclerotic plaque in male athletes compared to sedentary controls. However, the plaques found in athletes were more prone to be calcified. The pathogenesis and clinical relevance of this athlete coronary artery disease phenotype remains incompletely understood and represents an area of important future work.

Positive Emotion in Generalized Anxiety Disorder

2019 ◽  
pp. 297-311
Author(s):  
Ilana Seager ◽  
Douglas S. Mennin ◽  
Amelia Aldao
Keyword(s):  
Anxiety Disorder ◽  
Positive Affect ◽  
Generalized Anxiety Disorder ◽  
Positive Emotion ◽  
Behavioral Therapy ◽  
Generalized Anxiety ◽  
Emotional Dysfunction ◽  
Wide Range ◽  
Future Work

Generalized anxiety disorder (GAD) is a debilitating condition characterized by excessive, pervasive, uncontrollable, and paralyzing worries about a wide range of future situations. Individuals with this condition frequently find themselves stuck in worry and tension cycles in futile attempts at reducing uncertainty and increasing control. GAD has been associated with substantial impairments in functioning and reduced quality of life. GAD remains poorly understood, and the long-term efficacy and end-state functioning resulting from treatment are weaker compared to other anxiety disorders. Some treatments (e.g., emotion regulation therapy, acceptance-based behavioral therapy) have improved efficacy, partly by targeting emotional dysfunction. Basic psychopathology research has focused on identifying the role of negative affect in GAD, so little is known about how positive affect is experienced and regulated in this disorder. This is particularly important in light of the overlap of this condition with major depressive disorder, which is characterized by low or suppressed positive emotion. Developing such an understanding is essential to further improve the efficacy of emotion-based treatments. This chapter reviews current and future directions in the study of positive affect in GAD. The chapter reviews the nascent research on positive affect and GAD, then illustrates dimensions of future work.

scholarly journals High-strength and fibrous capsule–resistant zwitterionic elastomers

2021 ◽  
Vol 7 (1) ◽  
pp. eabc5442
Author(s):  
Dianyu Dong ◽  
Caroline Tsao ◽  
Hsiang-Chieh Hung ◽  
Fanglian Yao ◽  
Chenjue Tang ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Mechanical Strength ◽  
High Strength ◽  
Design Principles ◽  
Fibrous Capsule ◽  
High Mechanical Strength ◽  
Capsule Formation ◽  
Locking Mechanism ◽  
Fibrous Capsule Formation

The high mechanical strength and long-term resistance to the fibrous capsule formation are two major challenges for implantable materials. Unfortunately, these two distinct properties do not come together and instead compromise each other. Here, we report a unique class of materials by integrating two weak zwitterionic hydrogels into an elastomer-like high-strength pure zwitterionic hydrogel via a “swelling” and “locking” mechanism. These zwitterionic-elastomeric-networked (ZEN) hydrogels are further shown to efficaciously resist the fibrous capsule formation upon implantation in mice for up to 1 year. Such materials with both high mechanical properties and long-term fibrous capsule resistance have never been achieved before. This work not only demonstrates a class of durable and fibrous capsule–resistant materials but also provides design principles for zwitterionic elastomeric hydrogels.

Progress and Prospects for the Development of Computer-Generated Actors for Military Simulation: Part 1-Introduction and Background

2003 ◽  
Vol 12 (3) ◽  
pp. 311-325 ◽  
Author(s):  
Martin R. Stytz ◽  
Sheila B. Banks
Keyword(s):  
Research Area ◽  
Background Information ◽  
Life Cycle Costs ◽  
Material Management ◽  
Reasoning System ◽  
Force Structure ◽  
The Cost ◽  
Future Work ◽  
Level Training ◽  
Made In

The development of computer-generated synthetic environments, also calleddistributed virtual environments, for military simulation relies heavily upon computer-generated actors (CGAs) to provide accurate behaviors at reasonable cost so that the synthetic environments are useful, affordable, complex, and realistic. Unfortunately, the pace of synthetic environment development and the level of desired CGA performance continue to rise at a much faster rate than CGA capability improvements. This insatiable demand for realism in CGAs for synthetic environments arises from the growing understanding of the significant role that modeling and simulation can play in a variety of venues. These uses include training, analysis, procurement decisions, mission rehearsal, doctrine development, force-level and task-level training, information assurance, cyberwarfare, force structure analysis, sustainability analysis, life cycle costs analysis, material management, infrastructure analysis, and many others. In these and other uses of military synthetic environments, computer-generated actors play a central role because they have the potential to increase the realism of the environment while also reducing the cost of operating the environment. The progress made in addressing the technical challenges that must be overcome to realize effective and realistic CGAs for military simulation environments and the technical areas that should be the focus of future work are the subject of this series of papers, which survey the technologies and progress made in the construction and use of CGAs. In this, the first installment in the series of three papers, we introduce the topic of computer-generated actors and issues related to their performance and fidelity and other background information for this research area as related to military simulation. We also discuss CGA reasoning system techniques and architectures.

scholarly journals Organization, operations, and success of environmental organized crime in Italy and India: A comparative analysis

2016 ◽  
Vol 14 (2) ◽  
pp. 160-182 ◽  
Author(s):  
Aunshul Rege ◽  
Anita Lavorgna
Keyword(s):  
Comparative Analysis ◽  
Organized Crime ◽  
Research Area ◽  
Sand Mining ◽  
Short And Long Term ◽  
Operational Practices ◽  
Organized Crime Groups ◽  
Organizational Mechanisms ◽  
Environmental Crimes

Despite the devastating short- and long-term consequences of resource-related environmental crimes, rampant illegal soil and sand mining continues worldwide. In countries such as India and Italy, organized crime groups have emerged as prominent illegal suppliers of soil and sand. The proposed study focuses on an understudied research area at the intersection between organized crime and environmental crimes, and offers a trans-comparative study of illegal soil and sand mining conducted by Indian and Italian organized crime groups with two main objectives. First, a comparative analysis of the organizational mechanisms, operational practices, threat management, and supporting cultural, regulatory, and policing factors is conducted. Second, a discussion of how these groups reflect mainstream models and theories of organized crime is offered.

A Retrospective Comparison of American Women’s Spontaneous Conceptions and Gestational Surrogate Pregnancies

2021 ◽  
Author(s):  
Jennifer Lahl ◽  
Kallie Fell ◽  
Kate Bassett ◽  
Frances Broghammer ◽  
Maggie Eastman ◽  
...  
Keyword(s):  
Ethical Issues ◽  
Demographic Data ◽  
Health Issues ◽  
Structured Interviews ◽  
Survey Tool ◽  
Level Data ◽  
Retrospective Comparison ◽  
Caucasian Women ◽  
Future Work

Abstract Purpose: To evaluate the retrospective pregnancy experiences of American women by comparing spontaneous pregnancies with gestational surrogate pregnancies. Methods: Data were collected via structured interviews following an approved survey tool utilizing an online video platform. In total, 97 interviews were conducted. Results: Demographic data was collected on age, ethnicity, primary language, country of birth, education, and income level. Data revealed that a woman was more likely to have a pregnancy that was high-risk during a surrogate pregnancy than a non-surrogate pregnancy, independent of maternal age or gravidity (OR 7.22, p<0.001). A surrogate pregnancy had 4 times higher odds of resulting in a c-section (p<0.001) as well as delivering at an earlier gestational age (p<0.001). Further, women were more likely to experience adverse effects, including postpartum depression, following delivery of a surrogate child than their own biological child (p<0.001). Finally, the rate of new post-surrogacy chronic health issues for non-Caucasian women was significantly higher than for Caucasians (p<0.001). Women reported using the payment they received for their surrogacy for basic needs. Almost half of the women reported using the money to pay bills or get out of debt.Conclusions: These results are among the first of their kind. This study reveals that surrogate health disparities exist and that there may be long-term complications after a surrogate pregnancy. This raises important social, economic, and ethical issues related to surrogacy which must be further explored. Future work will build on this study and help elucidate the circumstances and consequences surrounding this complex issue.

Radiation protection perspective to recurrent medical imaging: what is known and what more is needed?

2021 ◽  
pp. 20210477
Author(s):  
Jenia Vassileva ◽  
Ola Holmberg
Keyword(s):  
Radiation Protection ◽  
Current Knowledge ◽  
Clinical History ◽  
Patient Specific ◽  
Individual Radiosensitivity ◽  
Dose Saving ◽  
End Stage ◽  
Future Work ◽  
Standardised Patient

This review summarises the current knowledge about recurrent radiological imaging and associated cumulative doses to patients. The recent conservative estimates are for around 0.9 million patients globally who cumulate radiation doses above 100 mSv, where evidence exists for cancer risk elevation. Around one in five is estimated to be under the age of 50. Recurrent imaging is used for managing various health conditions and chronic diseases such as malignancies, trauma, end-stage kidney disease, cardiovascular diseases, Crohn’s disease, urolithiasis, cystic pulmonary disease. More studies are needed from different parts of the world to understand the magnitude and appropriateness. The analysis identified areas of future work to improve radiation protection of individuals who are submitted to frequent imaging. These include access to dose saving imaging technologies; improved imaging strategies and appropriateness process; specific optimisation tailored to the clinical condition and patient habitus; wider utilisation of the automatic exposure monitoring systems with an integrated option for individual exposure tracking in standardised patient-specific risk metrics; improved training and communication. The integration of the clinical and exposure history data will support improved knowledge about radiation risks from low doses and individual radiosensitivity. The radiation protection framework will need to respond to the challenge of recurrent imaging and high individual doses. The radiation protection perspective complements the clinical perspective, and the risk to benefit analysis must account holistically for all incidental and long-term benefits and risks for patients, their clinical history and specific needs. This is a step toward the patient-centric health care.

Ramp It Up

2018 ◽  
Vol 45 (4) ◽  
pp. 302-311 ◽  
Author(s):  
Regan A. R. Gurung ◽  
Jana Hackathorn
Keyword(s):  
Teaching Methods ◽  
Course Design ◽  
Methods Course ◽  
Front Face ◽  
Models Of Teaching ◽  
Term Retention ◽  
Long Term Retention ◽  
Introductory Class ◽  
Future Work

The introductory psychology (Intro Psych) course is the bedrock of the psychology major and the front face of our discipline. The class not only provides a foundation for students in the major but also provides a comprehensive portrait of the discipline for nonmajors. Despite a sizable body of research focused on pedagogy related to the introductory class, there are many questions that remain unanswered. We provide a comprehensive review of scholarship related to the Intro Psych course and discuss current practices and concerns related to textbook options, as well as teaching methods, course design, assignments to help students learn, and students’ learning outcomes. Finally, we provide five major suggestions for future work. We charge researchers to identify major bottlenecks to learning, design multisite studies, measure moderators of learning, assess long-term retention, and design/assess different models of teaching Intro Psych.

scholarly journals The GOME-2 instrument on the Metop series of satellites: instrument design, calibration, and level 1 data processing – an overview

2016 ◽  
Vol 9 (3) ◽  
pp. 1279-1301 ◽  
Author(s):  
Rosemary Munro ◽  
Rüdiger Lang ◽  
Dieter Klaes ◽  
Gabriele Poli ◽  
Christian Retscher ◽  
...  
Keyword(s):  
Data Processing ◽  
Instrument Design ◽  
Data Consistency ◽  
Current Status ◽  
Web Pages ◽  
Ozone Monitoring ◽  
Level 1 ◽  
Future Work ◽  
Ground Calibration

Abstract. The Global Ozone Monitoring Experiment-2 (GOME-2) flies on the Metop series of satellites, the space component of the EUMETSAT Polar System. In this paper we will provide an overview of the instrument design, the on-ground calibration and characterization activities, in-flight calibration, and level 0 to 1 data processing. The current status of the level 1 data is presented and points of specific relevance to users are highlighted. Long-term level 1 data consistency is also discussed and plans for future work are outlined. The information contained in this paper summarizes a large number of technical reports and related documents containing information that is not currently available in the published literature. These reports and documents are however made available on the EUMETSAT web pages and readers requiring more details than can be provided in this overview paper will find appropriate references at relevant points in the text.

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