Data Mining Approach for the Early Risk Assessment of Gestational Diabetes Mellitus

Author(s):  
Saeed Rouhani ◽  
Maryam MirSharif

In this article, the authors proposed the method of medical diagnosis in gestational diabetes mellitus (GDM) in the initial stages of pregnancy to facilitate diagnoses and prevent the affection. Nowadays, in industrial modern world with changing lifestyle alimental manner the incidence of complex disease has been increasingly grown. GDM is a chronic disease and one of the major health problems that is often diagnosed in middle or late period of pregnancy, when it is too late for prediction. If it is not treated, it will make serious complications and various side effects for mother and child. This article is designed for answering to the question of: “What is the best approach in timely and accurate prediction of GDM?” Thus, the artificial neural network and decision tree are proposed to reduce the amount of error and the level of accuracy in anticipating and improving the precision of prediction. The results illustrate that intelligent diagnosis systems can improve the quality of healthcare, timely prediction, prevention, and knowledge discovery in bioinformatics.

Author(s):  
Aleeza Pal ◽  
Bishan Dhiman ◽  
Rita Mittal ◽  
Bhaskar J. Paul

Background: Gestational Diabetes Mellitus (GDM) is defined as carbohydrate intolerance of variable severity with the onset or first recognition during pregnancy. It is a disease entity that adversely affects maternal as well as fetal outcome. DIPSI guideline having suggested one-time plasma glucose level has emerged as a simple, practical and cheap method to detect GDM. This study was done to evaluate the prevalence of gestational diabetes using Diabetes in Pregnancy Study Group India (DIPSI) criteria and further assess its feto maternal outcome in Kamla Nehru State Hospital for Mother and Child, IGMC, Shimla.Methods: This study was conducted in 500 patients between 24 and 28 weeks of gestation, attending the antenatal OPD. These patients were given 75g oral glucose irrespective of last meal and their plasma glucose was estimated at 2h. Patients with plasma glucose ≥140mg/dl were diagnosed as GDM and the rest as control or the non GDM group. The GDM patients were followed up and treated with medical nutrition therapy (MNT) and/or insulin therapy till delivery and maternal and fetal outcomes were then noted.Results: The prevalence of GDM in this study was 6%. Maternal and fetal complications were more in the GDM patients. Vaginal candidiasis and PROM were the common maternal complications, while hypoglycemia and hyperbilirubinemia were common in the fetuses.Conclusions: GDM adversely affects the mother as well as fetus. DIPSI guideline having suggested a single plasma glucose level test has emerged as a practical and economical method to detect GDM.


2020 ◽  
Vol 12 (2) ◽  
Author(s):  
Ebtesam EL Sayed Shama ◽  
Nadra Mohamed Ibrahiem ◽  
Amal Roshdi Ahmed ◽  
Amany El-berdan ◽  
Eman El-Sherbeny

2009 ◽  
pp. 73-86
Author(s):  
Renata Tambelli ◽  
Manuela Errante

- In this review are discussed the main researches about high-risk pregnancy and, particularly, gestational diabetes mellitus (GDM). The results of these researches highlight that pregnant women with GDM are extremely vulnerable, anxious and worried. However there are not many clinical studies about the effect of GDM on the quality of mother-child relationship.


2019 ◽  
Author(s):  
samira mokhlesi ◽  
masoumeh simbar ◽  
fahimeh ramezani tehrani ◽  
Nourossadat kariman ◽  
hamid alavi majd

Abstract Background Gestational diabetes mellitus carries serious risks to mother and fetus and causes social, mental, and psychological consequences which can affect mothers’ quality of life. Accordingly, this study aims to develop and assess the psychometric properties of quality of life questionnaire for women with gestational diabetes mellitus. Methods A methodological study of sequential exploratory mixed method was developed and implemented. It included qualitative (development of a quality of life questionnaire for mothers with GDM) and quantitative (assessment of psychometric prosperities of quality of life questionnaire for mothers with GDM) phases. Results Based on the findings of the qualitative phase and literature review, the primary questionnaire was prepared with 142 items. The outcome of face validity and content validity assessment was a 67-item questionnaire. S-CVI and S-CVR turned out to be 0.92 and 0.68, respectively. The results of exploratory factor analysis yielded an instrument with 36 items in five domains including concerns about high-risk pregnancy, perceived constraints, disease complications, medication and treatment, and support. Five factors explained 46.68% of the total variance of the questionnaire. The results indicated a moderate and significant correlation between the questionnaire of “Diabetes Clients Quality Of Life” and the researcher-made questionnaire (r=0.63). Cronbach’s alpha coefficient for the entire scale was 0.93 and the intra-class correlation coefficient was 0.95. Conclusion Quality of life questionnaire for mothers with GDM is a valid and reliable tool capable of measuring the quality of life of women with GDM.


Proceedings ◽  
2019 ◽  
Vol 37 (1) ◽  
pp. 26
Author(s):  
Manerkar ◽  
Harding ◽  
Conlon ◽  
McKinlay

Gestational diabetes mellitus (GDM) is a major health problem not only in pregnancy but alsofor lifelong health, with increased risks of obesity and diabetes in offspring [...]


2020 ◽  
Vol 2020 ◽  
pp. 1-11 ◽  
Author(s):  
Yucui Teng ◽  
Shuxia Xuan ◽  
Ming Jiang ◽  
Li Tian ◽  
Jinjing Tian ◽  
...  

Background. Gestational diabetes mellitus (GDM) is a severe threat to the health of both mother and child. The pathogenesis of GDM remains unclear, although much research has found that the levels of hydrogen sulfide (H2S) play an important role in complications of pregnancy. Methods. We collected venous blood samples from parturient women and umbilical vein blood (UVB) and peripheral venous blood (PVB) samples one hour after childbirth in the control, GDM-, and GDM+ groups in order to determine the concentration of glucose and H2S in plasma; to measure levels of TNF-α, IL-1β, IL-6, TGF-β1, and ADP in parturient women and the UVB of newborns; and to find the correlation of H2S with regression. Results. We found that, with the elevation of glucose, the level of H2S was decreased in GDM pregnant women and newborns and the concentrations of IL-6 and TNF-α were upregulated. With regression, IL-6 and TNF-α concentrations were positively correlated with the level of blood glucose and negatively correlated with H2S concentration. Conclusion. This study shows that downregulation of H2S participates in the pathogenesis of GDM and is of great significance in understanding the difference of H2S between normal and GDM pregnant women and newborns. This study suggests that IL-6 and TNF-α are correlated with gestational diabetes mellitus. The current study expands the knowledge base regarding H2S and provides new avenues for exploring further the pathogenesis of GDM.


2019 ◽  
Vol 28 (5) ◽  
pp. 1349-1354 ◽  
Author(s):  
Kyriakos A. Pantzartzis ◽  
Philip P. Manolopoulos ◽  
Stavroula A. Paschou ◽  
Kyriakos Kazakos ◽  
Kalliopi Kotsa ◽  
...  

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