Remarks to Calibration in Chemistry

2012 ◽  
Vol 2 (1) ◽  
pp. 67-76
Author(s):  
Viliam Patoprsty ◽  
Miroslava Valkova
Keyword(s):  
Reference Material ◽  
Measurement Method ◽  
Certified Reference Materials ◽  
Metrological Traceability ◽  
Indirect Measurement ◽  
Measuring Instrument ◽  
Real Situation ◽  
Stated Reference ◽  
The Relationship ◽  
Crm Certification

Calibration is the operation establishing metrological traceability of values of calibrated measuring instrument scale (or reference material) to stated reference. In the case of indirect measurement it is necessary to know the relationship between determined quantity values and corresponding measurand values. If mathematic form of this relationship is unknown, it is substituted by its approximation. In this process a real situation is simplified by neglecting of influence quantities to a relation of two variables- independent versus dependent. Metrological traceability of certified reference materials (CRM) values intended for calibration purposes and characterised by means of a method working on the base of approximative function could be questionable. If a measurement method based on original relationship already exists, it should be strongly preferred in the process of CRM certification to methods based on approximation of original relationship.

scholarly journals The problem of improving the quality of seriously issued certified reference materials of the composition of gas mixtures

2019 ◽  
Vol 15 (3) ◽  
pp. 5-13
Author(s):  
L. A. Konopelko ◽  
A. V. Kolobova ◽  
O. V. Fatina
Keyword(s):  
Reference Material ◽  
Reference Materials ◽  
Certified Reference Materials ◽  
Metrological Traceability ◽  
Gas Mixtures ◽  
Measuring Instruments ◽  
Expanded Uncertainty ◽  
Iso Guide 35 ◽  
The Russian Federation

Currently, in the Russian Federation, the metrological traceability of certified reference materials of the composition of gas mixtures in cylinders under pressure produced by manufacturers of certified reference materials is carried out in accordance with GOST 8.578-2014. Considering that certified reference materials of the composition of gas mixtures in cylinders under pressure are used for testing to approye the type of measuring instruments, verification, calibration, and graduation of gas-analytical measuring instruments used to control explosive gases and vapors, harmful components in the atmospheric air and the air of the working area, emissions from vehicles and enterprises, to control technological processes, the quality of hydrocarbon products, etc., the issue of ensuring the quality of seriously produced certified reference materials (about 100.000 cylinders with gas mixtures per year) is important. To ensure the quality of certified reference materials of gas mixtures in cylinders under pressure, mass-produced by manufacturers of certified reference materials, we offer the following actions:– manufacturers of certified reference materials’ passing of mandatory accreditation for compliance with the requirements of GOST ISO Guide 34–2014 and GOST ISO Guide 35–2015;– manufacturers of certified reference materials’ constant participation in the proficiency testing programs through interlaboratory tests;– actualizing and refining the existing set of standards defining the requirements for the entire life cycle of a certified reference material of a gas mixture in a cylinder under pressure;– improving the method of certification of a reference material by calculating the value of the expanded uncertainty of the reference material and the introducting a new coefficient «technological reserve».

The Study on the Compensation for Displacement of Multi-Way Valve Main Spool

2014 ◽  
Vol 852 ◽  
pp. 432-436
Author(s):  
Jin Gang Liu ◽  
Shui Zhang Kuang ◽  
Jian Ren Zhu ◽  
Jian Wen Chen
Keyword(s):  
Steady State ◽  
Measurement Method ◽  
Reference Value ◽  
Indirect Measurement ◽  
Compensation Method ◽  
Force Analysis ◽  
Flow Area ◽  
Fluid Force ◽  
Spring Force ◽  
The Relationship

A compensation algorithm, based on the steady-state fluid force of spool, was proposed to reduce the error between the actual and theoretical spool displacement obtained from indirect measurement method and equilibrium of the pilot pressure and spring force, respectively. The steady-state fluid force of spool was calculated and the force analysis was carried out on the spool. Study on the influence of the steady-state fluid force on spool displacement during the spool movement. Finally, the relationship curve between the compensated flow area of valve port and the spool displacement was established. The error of spool displacement was effectively reduced and the accuracy of the test was improved by the proposed compensation method, thus it can provide certain reference value for the design of multi-way valves.

Multi-Center Calibration of the Second Reference Material for Thromboplastin, Rabbit, Plain, Coded CRM 149R

1991 ◽  
Vol 65 (03) ◽  
pp. 263-267 ◽  
Author(s):  
A M H P van den Besselaar ◽  
R M Bertina
Keyword(s):  
Reference Material ◽  
Standard Error ◽  
Standard Errors ◽  
Sensitivity Index ◽  
Long Term Stability ◽  
Significant Bias ◽  
The Mean ◽  
The Relationship ◽  
International Sensitivity Index

SummaryIn a collaborative trial of eleven laboratories which was performed mainly within the framework of the European Community Bureau of Reference (BCR), a second reference material for thromboplastin, rabbit, plain, was calibrated against its predecessor RBT/79. This second reference material (coded CRM 149R) has a mean International Sensitivity Index (ISI) of 1.343 with a standard error of the mean of 0.035. The standard error of the ISI was determined by combination of the standard errors of the ISI of RBT/79 and the slope of the calibration line in this trial.The BCR reference material for thromboplastin, human, plain (coded BCT/099) was also included in this trial for assessment of the long-term stability of the relationship with RBT/79. The results indicated that this relationship has not changed over a period of 8 years. The interlaboratory variation of the slope of the relationship between CRM 149R and RBT/79 was significantly lower than the variation of the slope of the relationship between BCT/099 and RBT/79. In addition to the manual technique, a semi-automatic coagulometer according to Schnitger & Gross was used to determine prothrombin times with CRM 149R. The mean ISI of CRM 149R was not affected by replacement of the manual technique by this particular coagulometer.Two lyophilized plasmas were included in this trial. The mean slope of relationship between RBT/79 and CRM 149R based on the two lyophilized plasmas was the same as the corresponding slope based on fresh plasmas. Tlowever, the mean slope of relationship between RBT/79 and BCT/099 based on the two lyophilized plasmas was 4.9% higher than the mean slope based on fresh plasmas. Thus, the use of these lyophilized plasmas induced a small but significant bias in the slope of relationship between these thromboplastins of different species.

Analysis of significant measures for thermal conductivity

2020 ◽  
pp. 35-42
Author(s):  
Yuri P. Zarichnyak ◽  
Vyacheslav P. Khodunkov
Keyword(s):  
Thermal Conductivity ◽  
Heat Flux ◽  
Surface Heat Flux ◽  
Heat Flux Density ◽  
Measurement Method ◽  
Conductivity Measurement ◽  
Surface Heat ◽  
Measuring Instrument ◽  
New Class ◽  
Achievable Accuracy

The analysis of a new class of measuring instrument for heat quantities based on the use of multi-valued measures of heat conductivity of solids. For example, measuring thermal conductivity of solids shown the fallacy of the proposed approach and the illegality of the use of the principle of ambiguity to intensive thermal quantities. As a proof of the error of the approach, the relations for the thermal conductivities of the component elements of a heat pump that implements a multi-valued measure of thermal conductivity are given, and the limiting cases are considered. In two ways, it is established that the thermal conductivity of the specified measure does not depend on the value of the supplied heat flow. It is shown that the declared accuracy of the thermal conductivity measurement method does not correspond to the actual achievable accuracy values and the standard for the unit of surface heat flux density GET 172-2016. The estimation of the currently achievable accuracy of measuring the thermal conductivity of solids is given. The directions of further research and possible solutions to the problem are given.

PENGARUH INPUT PROSES RELATIONSHIP MARKETING TERHADAP OUTPUT PROSES RELATIONSHIP MARKETING

2019 ◽  
Vol 27 (2) ◽  
pp. 190-206
Author(s):  
Surawan Setya Budi S
Keyword(s):  
Relationship Marketing ◽  
Research Use ◽  
Measuring Instrument ◽  
Total Quality ◽  
Input Process ◽  
Customer Expectations ◽  
Simultaneous Test ◽  
Marketing Process ◽  
Process Understanding ◽  
The Relationship

This research use relationship marketing teory which applied 4 factor of input process understanding customer expectations, building service partnerships, empowiring employers, and total quality management, and output relationship marketing process: customer satisfaction and customer layalty. The objective of this research is to find out wich factors of input process that has more impact on the output process in relationship marketing. There are 60 trusted correspondencea from Grand Inna Malioboro Hotel customer whom at least have been stayed at the hotel three times. The method of collecting data in these research use questioners and Likert scale measuring instrument 5 points that will be tested by the instrument and analyzed by using regressision analysi the simultaneous test of variabel for the relationship marketing input s. The result of the instrument shows the items used are valid and reliable. It displays the outpout process passed the assumtions test, while the signifikacant relationship marketingto the output of relationtionship marketing, For the passive test of vareable input process relationship marketing with the ouput process relationship marketing shows all significant variables unless vareabel understands customer expectations does not have a significant effect on the process of output relationship marketing

Development and Certification of Formononetin Reference Material for Quality Control of Functional Foods and Botanical Supplements

2019 ◽  
Vol 15 (5) ◽  
pp. 553-559
Author(s):  
Ningbo Gong ◽  
Baoxi Zhang ◽  
Kun Hu ◽  
Zhaolin Gao ◽  
Guanhua Du ◽  
...  
Keyword(s):  
Quality Control ◽  
Reference Material ◽  
Functional Foods ◽  
Certified Reference Materials ◽  
Coulometric Titration ◽  
Pharmaceutical Formulations ◽  
Uncertainty Estimation ◽  
Expanded Uncertainty ◽  
Scanning Calorimetry ◽  
Botanical Supplements

Background: Formononetin is a common soy isoflavonoid that can be found abundantly in many natural plants. Previous studies have shown that formononetin possesses a variety of activities which can be applied for various medicinal purposes. Certified Reference Materials (CRMs) play a fundamental role in the food, traditional medicine and dietary supplement fields, and can be used for method validation, uncertainty estimation, as well as quality control. Methods: The purity of formononetin was determined by Differential Scanning Calorimetry (DSC), Coulometric Titration (CT) and Mass Balance (MB) methods. Results: This paper reports the sample preparation methodology, homogeneity and stability studies, value assignment, and uncertainty estimation of a new certified reference material of formononetin. DSC, CT and MB methods proved to be sufficiently reliable and accurate for the certification purpose. The purity of the formononetin CRM was therefore found to be 99.40% ± 0.24 % (k = 2) based on the combined value assignments and the expanded uncertainty. Conclusion: This CRM will be a reliable standard for the validation of the analytical methods and for quality assurance/quality control of formononetin and formononetin-related traditional herbs, food products, dietary supplements and pharmaceutical formulations.

scholarly journals Development and certification of a reference material for zearalenone in maize germ oil

2021 ◽  
Author(s):  
Juliane Riedel ◽  
Sebastian Recknagel ◽  
Diana Sassenroth ◽  
Tatjana Mauch ◽  
Sabine Buttler ◽  
...  
Keyword(s):  
Reference Material ◽  
Reference Materials ◽  
Mass Fraction ◽  
High Performance ◽  
Certified Reference Materials ◽  
Maximum Level ◽  
Whole Process ◽  
Commission Regulation ◽  
Maize Oil ◽  
Maize Germ

AbstractZearalenone (ZEN), an estrogenic mycotoxin produced by several species of Fusarium fungi, is a common contaminant of cereal-based food worldwide. Due to frequent occurrences associated with high levels of ZEN, maize oil is a particular source of exposure. Although a European maximum level for ZEN in maize oil exists according to Commission Regulation (EC) No. 1126/2007 along with a newly developed international standard method for analysis, certified reference materials (CRM) are still not available. To overcome this lack, the first CRM for the determination of ZEN in contaminated maize germ oil (ERM®-BC715) was developed in the frame of a European Reference Materials (ERM®) project according to the requirements of ISO Guide 35. The whole process of CRM development including preparation, homogeneity and stability studies, and value assignment is presented. The assignment of the certified mass fraction was based upon an in-house study using high-performance liquid chromatography isotope dilution tandem mass spectrometry. Simultaneously, to support the in-house certification study, an interlaboratory comparison study was conducted with 13 expert laboratories using different analytical methods. The certified mass fraction and expanded uncertainty (k = 2) of ERM®-BC715 (362 ± 22) μg kg−1 ZEN are traceable to the SI. This reference material is intended for analytical quality control and contributes to the improvement of consumer protection and food safety. Graphical abstract

Thickness Indirect Measurement Method for Direct Pulling Pilot Cold Rolling Mill

2011 ◽  
Vol 189-193 ◽  
pp. 2670-2674
Author(s):  
Zhi Jie Jiao ◽  
Chun Yu He ◽  
Jian Ping Li ◽  
Xiang Hua Liu
Keyword(s):  
Cold Rolling ◽  
Rolling Mill ◽  
Measurement Method ◽  
Rolling Process ◽  
Indirect Measurement ◽  
Cold Rolling Mill ◽  
Movement Data ◽  
Program Flow ◽  
New Type ◽  
Exit Speed

Pilot cold rolling mill is the important tool for the cold rolling process researching and new steel grade development. According to the design of the new type direct pulling pilot cold rolling mill, based on the mass flow constant principle, strip exit thickness indirect measurement method is studied. During rolling, strip entry and exit speed can be calculated accurately according to the measured value of two sides’ clamps movement. Data filtering treatment is adopted and program flow chart is designed. Based on the material entry thickness measured manually, exit thickness of all passes can be measured indirectly. This thickness indirect measurement method has been applied successfully on the new type pilot cold rolling mill, and the measurement results show that this method has a good accuracy.

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