Synthesis and Drug Release from a PH/Temperature Sensitive Bead of Poly(N-Acryloylglycinate) and Alginate
2011 ◽
Vol 117-119
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pp. 1227-1230
Keyword(s):
In this paper, a new pH/temperature sensitive beads with core-shelled structure, composed of sodium alginate and poly(N-acryloylglycinate), were prepared using as drug delivery carrier. Selecting indomethacin as a model drug, in vitro drug release behaviors were investigated at different temperatures, phosphate buffer solutions (PBS) and polymer content. At pH=2.1, the release amount of indomethacin loaded in the beads was only 2.46% while this value approached to 95.23% in pH=7.4 PBS. In addition, the release rate of indomethacin at 37°C is much higher than at 18°C.
Drug Release Behaviors of a Novel Ph/Temperature Responsive Hydrogel with Jujube Cake-Like Structure
2010 ◽
Vol 148-149
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pp. 994-997
2020 ◽
Vol 13
(01)
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Keyword(s):
2017 ◽
Vol 10
(5)
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pp. 166
2019 ◽
Vol 556
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pp. 311-319
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Keyword(s):
2019 ◽
Vol 225
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pp. 122-132
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2010 ◽
Vol 148-149
◽
pp. 1427-1430
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2021 ◽
Vol 16
(7)
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pp. 1029-1036
Keyword(s):
Keyword(s):
2020 ◽
Vol 28
(5)
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pp. 538-549
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