Study on the Preparation, Property and Drug Release Carrier of Chitosan-Based Nanoparticles for Cancer Treatment

2011 ◽  
Vol 284-286 ◽  
pp. 1800-1803
Author(s):  
Chih Wei Chou ◽  
Yueh Hsiung Kuo ◽  
You Cheng Hseu ◽  
Yung Shiu Chen ◽  
Te Hsing Wu
Keyword(s):  
Electron Microscope ◽  
Near Infrared ◽  
Ultra Violet ◽  
Drug Carriers ◽  
Therapeutic Agents ◽  
Synthetic Method ◽  
Grafting Reaction ◽  
Transmission Electron ◽  
Infrared Spectrophotometer ◽  
Ft Ir

In this paper, the effective nanocompoties (EFNCs) as drug carriers are prepared by grafting reaction of cationic chitosan (CS) and anionic tripolyphosphate (TPP) to encapsulate cancer therapeutic agents such as berberine (BB), KCY-24B…etc. These EFNCs were featured by ultra violet–visible-near infrared spectrophotometer (UV-VIS-NIR spectrophotometer), fourier transform infrared spectrophotometer (FT-IR), zetasizer, transmission electron microscope (TEM) and field-emission scanning electron microscope (FESEM). So we can obtain here the synthetic method, characterization, and functionality of these effective nanoparticles.

Herbal-Loaded Multifunctional Nanocomposities as Nanocarrier for Cancer Therpy: Synthesis and Quality

2011 ◽  
Vol 311-313 ◽  
pp. 1625-1629 ◽  
Author(s):  
Chih Wei Chou ◽  
Sheng Yueh Chang ◽  
Yung Shiu Chen ◽  
Wu Chung Su ◽  
Te Hsing Wu
Keyword(s):  
Electron Microscope ◽  
Near Infrared ◽  
Colon Adenocarcinoma ◽  
Ultra Violet ◽  
Human Colon ◽  
Size Analysis ◽  
Transmission Electron ◽  
Infrared Spectrophotometer ◽  
Ft Ir ◽  
Human Colon Adenocarcinoma

The multifunctional nanocompoties (MFNCs) as drug release carriers are prepared by cross-linking reaction of cationic chitosan (CS) and anionic tripolyphosphate (TPP) to encapsulate Fe3O4 nanoparticles(NPs) loaded cancer therapeutic agents such as berberine (BB), KCY-24B, KCY-Tai…etc were studied. These MFNCs were characterized by fourier transform infrared spectrophotometer (FT-IR), ultra violet–visible-near infrared spectrophotometer (UV-VIS-NIR spectrophotometer), size analysis, transmission electron microscope (TEM) and field-emission scanning electron microscope (FESEM). Then we obtained here the preparation method, characterization, and capability of these efficative nanoparticles. Cell celluar uptake and distribution of MFNCs were also inspected in human colon adenocarcinoma cell lines (Colo 205).

Synthesis of Uniform and High Density Silver Nanoparticles by using Peltophorum pterocarpum flower Extract

2014 ◽  
Vol 1584 ◽  
Author(s):  
Matheswaran BALAMURUGAN ◽  
Shanmugam SARAVANAN ◽  
Naoki OHTANI
Keyword(s):  
Silver Nanoparticles ◽  
Fourier Transform ◽  
Electron Microscope ◽  
Ultra Violet ◽  
Capping Agent ◽  
Nanosized Particles ◽  
Flower Extract ◽  
Transmission Electron ◽  
Vis Spectroscopy ◽  
Ft Ir

ABSTRACTSilver nanoparticle (AgNP) is one of the elegant material because its uses in various fields. In this study, AgNPs have been prepared by using Peltophorum pterocarpum (PP) flower extract as reducing and capping agent and aqueous silver nitrate (aq.AgNO3) as silver precursor. The synthesized nanoparticles were characterized using Ultra Violet - Visible (UV-Vis) spectroscopy, High Resolution Transmission Electron Microscope (HR-TEM) and Fourier Transform Infrared Spectroscopy (FT-IR), which reveals the formation of nanosized particles. The UV-Vis spectrum shows an absorption peak around 430nm. HR-TEM images of AgNPs with clear morphology and well dispersed prepared AgNPs.

scholarly journals A Facile Urea-Assisted Thermal Decomposition Process of TiO2 Nanoparticles and Their Photocatalytic Activity

Coatings ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 165
Author(s):  
Sandip Madhukar Deshmukh ◽  
Mohaseen S. Tamboli ◽  
Hamid Shaikh ◽  
Santosh B. Babar ◽  
Dipak P. Hiwarale ◽  
...  
Keyword(s):  
Thermal Decomposition ◽  
Photocatalytic Activity ◽  
Tio2 Nanoparticles ◽  
Large Scale ◽  
Ultra Violet ◽  
Tio2 Nps ◽  
Transmission Electron ◽  
Structures And Properties ◽  
Ft Ir ◽  
Large Scale Synthesis

In the present work, we have reported a facile and large-scale synthesis of TiO2 nanoparticles (NPs) through urea-assisted thermal decomposition of titanium oxysulphate. We have successfully synthesized TiO2 NPs by using this effective route with different weight ratios of titanium oxysulphate: urea. The structures and properties of TiO2 NPs were confirmed by scanning electron microscope) (SEM), transmission electron microscopy (TEM), thermogravimetric analysis (TGA), fourier transform infrared spectroscopy (FT-IR), ultra violet–visible spectroscopy (UV-vis), and photoluminescence (Pl) techniques. XRD demonstrated that TiO2 NPs holds of anatase crystal phase with crystallizing size 14–19 nm even after heating at 600 °C. TGA, SEM, and TEM images reveal urea’s role, which controls the size, morphology, and aggregation of TiO2 NPs during the thermal decomposition. These TiO2 NPs were employed for photodegradation of Methyl Orange (MO) in the presence of ultraviolet (UV) radiation. An interesting find was that the TiO2 NPs exhibited better photocatalytic activity and excellent recycling stability over several photodegradation cycles. Furthermore, the present method has a great perspective to be used as an efficient method for large-scale synthesis of TiO2 NPs.

scholarly journals Optimization and Application of Bioflocculant Passivated Copper Nanoparticles in the Wastewater Treatment

2019 ◽  
Vol 16 (12) ◽  
pp. 2185 ◽  
Author(s):  
Nkosinathi Goodman Dlamini ◽  
Albertus Kotze Basson ◽  
Viswanadha Srirama Rajasekhar Pullabhotla
Keyword(s):  
Electron Microscope ◽  
Removal Efficiency ◽  
Copper Nanoparticles ◽  
Antimicrobial Properties ◽  
Domestic Wastewater ◽  
X Ray Diffraction ◽  
Great Opportunity ◽  
Transmission Electron ◽  
Flocculation Activity ◽  
Ft Ir

Nanotechnology offers a great opportunity for efficient removal of pollutants and pathogenic microorganisms in water. Copper nanoparticles were synthesized using a polysaccharide bioflocculant and its flocculation, removal efficiency, and antimicrobial properties were evaluated. The synthesized nanoparticles were characterized using thermogravimetry, UV-Visible spectroscopy, Fourier-transform infrared spectroscopy (FT-IR), powder X-ray diffraction, scanning electron microscope (SEM), and transmission electron microscope (TEM). The highest flocculation activity (FA) was achieved with the lowest concentration of copper nanoparticles (0.2 mg/mL) with 96% (FA) and the least flocculation activity was 80% at 1 mg/mL. The copper nanoparticles (CuNPs) work well without the addition of the cation as the flocculation activity was 96% and worked best at weak acidic, neutral, and alkaline pH with the optimal FA of 96% at pH 7. Furthermore, the nanoparticles were found to be thermostable with 91% FA at 100 °C. The synthesized copper nanoparticles are also high in removal efficiency of staining dyes, such as safranin (92%), carbol fuchsine (94%), malachite green (97%), and methylene blue (85%). The high removal efficiency of nutrients such as phosphate and total nitrogen in both domestic wastewater and Mzingazi river water was observed. In comparison to ciprofloxacin, CuNPs revealed some remarkable properties as they are able to kill both the Gram-positive and Gram-negative microorganisms.

Preparation and Characterization of Magnetic Strong-Base Anion Exchange Resin

2011 ◽  
Vol 239-242 ◽  
pp. 1838-1841 ◽  
Author(s):  
Chen Dong Shuang ◽  
Feng Yang ◽  
Yang Zhou ◽  
Peng Hui Li ◽  
Ai Min Li
Keyword(s):  
Electron Microscope ◽  
Anion Exchange ◽  
Exchange Resin ◽  
Anion Exchange Resin ◽  
Nano Particles ◽  
Nano Particle ◽  
Strong Base ◽  
Transmission Electron ◽  
Ft Ir ◽  
Magnetic Nano Particles

The magnetic copolymer was prepared by polymerization of glycidyl methacrylate (GMA) and divinylbenzene (DVB) in the presence of OA-modified magnetic nano-particles. The magnetic strong-base anion exchange resin (MAER) was formed by quaternization of magnetic copolymer. Transmission electron microscope (TEM) and scanning electron microscope (SEM) were used for observation of prepared magnetic nano-particle and MAER, respectively. FT-IR spectrometer was used to characterize the magnetic nano-particle and MAER. To explore the potential application of MAER for natural organic matter (NOM) removal, completely-mixed (CMC) mode was used for humic acid (HA) adsorption. It was found that the HA removal for CMC mode with MAER resin was 10~20% higher than conventional process before breakthrough.

Synthesis of Anatase/Brookite Mixtured TiO2 Nanoparticles by a Chimie Douce Technique

2013 ◽  
Vol 734-737 ◽  
pp. 2528-2531
Author(s):  
Yu Mei Gong ◽  
Qing Liang ◽  
Jing Guo ◽  
Hong Zhang ◽  
Fu Cheng Guan
Keyword(s):  
Electron Microscope ◽  
Anatase Phase ◽  
Spherical Shape ◽  
Nitrogen Adsorption ◽  
X Ray Diffraction ◽  
Average Pore ◽  
Specific Pore Volume ◽  
Transmission Electron ◽  
Bet Method ◽  
Ft Ir

Anatase/brookite mixtured TiO2nanoparticles have been synthesized by using a two-step process through a chimie douce technique. The as-prepared powders were characterized by Fourier transform infrared (FT-IR) spectra, X-ray diffraction (XRD), transmission electron microscope (TEM), scanning electron microscope (SEM), and a nitrogen adsorption apparatus in multipoint Brunauer-Emmett-Teller (BET) method. The results indicated that the TiO2nanoparticles were composed of biphasial anatase/brookite mixtures, 38% anatase phase formed in quasi-spherical shape and 62% brookite phase formed in nanorod shape. The specific surface area, the average pore diameter, and the specific pore volume were 100.06 m2/g, 14.0 nm, and 0.561 cm3/g, respectively.

Enhanced optical, morphological, dielectric, and conductivity properties of gold nanoparticles doped PVA/CMC blend as an application in organoelectronic devices

2021 ◽  
Author(s):  
M. R. Atta ◽  
Qana M. Alsulami ◽  
G. M. Asnag ◽  
A . rajeh
Keyword(s):  
Gold Nanoparticles ◽  
Stevia Rebaudiana ◽  
Ultra Violet ◽  
X Ray Diffraction ◽  
Sem Images ◽  
Low Frequencies ◽  
Bright Spots ◽  
Transmission Electron ◽  
Ft Ir ◽  
Mobile Charges

Abstract Stevia rebaudiana plant leaves were used for biosynthesis of gold nanoparticles (AuNPs). Transmission electron microscope ( TEM ) images showed various shapes and sizes of AuNPs. Various amounts of AuNPs were added to polyvinyl alcohol/carboxymethylcellulose ( PVA / CMC , 40/60) via the casting method. The X-ray diffraction (XRD) spectrum of pure blend shows the amorphous nature of the blend. FT-IR spectra showed the interaction between PVA / CMC and AuNPs. The ultra-violet and visible (UV/VIS.) spectra showed emerge new peak of surface plasmon resonance ( SPR ) of AuNPs for the filled samples. SEM images showed bright spots on the sample's surface, which was attributed to AuNPs. AC conductivity exhibited enhancement after the addition of gold nanoparticles. The ε′ and ε″ were reduced with increasing the frequency due to direction dipoles of applied electric field. Because of the mobile charges inside the polymeric backbone, higher values of ε′ and ε″ were observed at low frequencies. The tanδ showed increased with an increase in AuNPs concentration and at the decrease the frequency, as expected.

Fabrication and Characterization of Nano-Sized Starch Particles

2015 ◽  
Vol 1120-1121 ◽  
pp. 275-280
Author(s):  
Hua Lin ◽  
Qing Li ◽  
Mu Feng ◽  
Li Zhao Qin
Keyword(s):  
Fourier Transform ◽  
Electron Microscope ◽  
Experimental Conditions ◽  
Transmission Electron ◽  
Infrared Spectrometer ◽  
Ft Ir ◽  
Plausible Mechanism ◽  
Fabrication And Characterization ◽  
The Fourier Transform

An efficient method of preparing nanostarch using high-intensity ultrasonic irradiation and acid hydrolysis was discussed. The transmission electron microscope (TEM) showed that the nanosized starch particles were in shape of sphere with the size of 80-120 nm, and their surfaces were rough with many flocci. The Fourier transform infrared spectrometer (FT-IR) revealed that the products maintained the original biological characteristics, and the molecules did not undergo any chemical changes. In addition, the effects of experimental conditions were analyzed and a plausible mechanism was proposed to explain the formation of the nanostarch.

scholarly journals Synthesis of Novel Azo-Linked 5-Amino-Pyrazole-4-Carbonitrile Derivatives Using Tannic Acid–Functionalized Silica-Coated Fe3O4 Nanoparticles as a Novel, Green, and Magnetically Separable Catalyst

2021 ◽  
Vol 9 ◽  
Author(s):  
Farhad Sedighi Pashaki ◽  
Mohammad Nikpassand
Keyword(s):  
Electron Microscope ◽  
Tannic Acid ◽  
Reaction Times ◽  
X Ray ◽  
H Nmr ◽  
Transmission Electron ◽  
Magnetically Separable Catalyst ◽  
Elemental Analyses ◽  
Ft Ir ◽  
High Yields

Tannic acid–linked silica-coated Fe3O4 nanoparticles (Fe3O4@SiO2@Tannic acid) were prepared and characterized by transmission electron microscope (TEM), field emission scanning electron microscope (FE-SEM), X-ray powder diffraction (XRD), X-ray spectroscopy (EDX), vibrating sample magnetometry (VSM), and Fourier transform infrared (FT-IR) spectroscopy. Fe3O4@SiO2@Tannic acid supplies an environmentally friendly procedure for the synthesis of some novel 5-amino-pyrazole-4-carbonitriles through the three-component mechanochemical reactions of synthetized azo-linked aldehydes, malononitrile, and phenylhydrazine or p-tolylhydrazine. These compounds were produced in high yields and at short reaction times. The catalyst could be easily recovered and reused for six cycles with almost consistent activity. The structures of the synthesized 5-amino-pyrazole-4-carbonitrile compounds were confirmed by 1H NMR, 13C NMR, and FTIR spectra, and elemental analyses.

The Production of Core-Shell Structure Carboxylated Carbon Nanotubes/Polypyrrole Composite Materials in Different Reaction Media and Further Investigation on their Core-Shell Structure

2017 ◽  
Vol 730 ◽  
pp. 37-41 ◽  
Author(s):  
Hui Li Cao ◽  
Yuan Chang Shi ◽  
Hao Shen ◽  
Hu Dong Zhan ◽  
Jiu Rong Liu
Keyword(s):  
Carbon Nanotubes ◽  
Electron Microscope ◽  
Composite Materials ◽  
Shell Structure ◽  
Core Shell ◽  
Transmission Electron ◽  
Ft Ir ◽  
Core Shell Structure ◽  
Polypyrrole Composite ◽  
Carboxylated Carbon Nanotubes

In this paper carboxylated carbon nanotubes/polypyrrole composite (CNTs/PPy) was synthesized in different surfactants aqueous under sonication. Carboxylated CNTs was synthesized in hydrogen nitrate by ultrasonic method and coated by PPy. The synthesized CNTs/PPy in different surfactants was evaluated by Fourier transform infrared spectrometer (FT-IR) and transmission electron microscope. The FT-IR patterns illustrate that CNTs were successfully doped by PPy. The morphology of CNTs/PPy synthesized showed on the transmission electron microscope images. The composite materials sythesized without surfactant are easy reunited. It is also found the surface of CNTs/PPy synthesized in cetyl trimethyl ammonium bromide (CTAB) is smoother than that in other surfactants. The coating effect is better with thicker coating layer. The higher magnification of HRTEM images show the PPy was deposited directly on the surface of carbon nanotubes. The final products are the ordered coaxial composite with well-defined core-shell structure.

Sign in / Sign up

Export Citation Format

Share Document