Fabrication of P2O5-CaO-Na2O Glasses Doped with Zinc Oxide for Artificial Bone Applications

2012 ◽  
Vol 506 ◽  
pp. 509-512 ◽  
Author(s):  
S. Thonglem ◽  
Sukum Eitssayeam ◽  
Gobwute Rujijanagul ◽  
Tawee Tunkasiri ◽  
Kamonpan Pengpat ◽  
...  
Keyword(s):  
Thermal Analysis ◽  
Differential Thermal Analysis ◽  
Infrared Spectra ◽  
Glass Melting ◽  
Artificial Bone ◽  
Layer Formation ◽  
In Vitro Bioactivity ◽  
Glass Transition Temperatures ◽  
Melting Technique

The purpose of this work was to study the effect of ZnO on properties of P2O5-CaO-Na2O glass system for bone substituting applications. The glass formula used in this study is 45P2O5- (30-x)CaO - 25Na2O - xZnO where x = 0, 1 , 3, and 5 mol%. The corresponding glasses were prepared by conventional glass melting technique at 1000 °C for 1 h. Thermal parameters of each glass were studied by differential thermal analysis (DTA). These glasses were investigated in terms of infrared spectra and in vitro bioactivity. DTA results gave the glass transition temperatures in a range 227-280°C and crystallization temperatures in the range 521-529°C. Form FTIR results, the infrared spectra of all glass samples showed vibrations of phosphate network and the transmittance intensity of glass systems decreased with increasing ZnO content. All glass samples were exhibited the growth of apatite cells at the surface after immersed in SBF for 7 days. The optimum composition was found for the glass samples containing 5 mol% ZnO which contained the most apatite layer formation.

Thermal analysis and in vitro bioactivity of bioactive glass–alumina composites

2011 ◽  
Vol 62 (1) ◽  
pp. 118-129 ◽  
Author(s):  
Xanthippi Chatzistavrou ◽  
Nikolaos Kantiranis ◽  
Eleana Kontonasaki ◽  
Konstantinos Chrissafis ◽  
Labrini Papadopoulou ◽  
...  
Keyword(s):  
Thermal Analysis ◽  
Bioactive Glass ◽  
In Vitro Bioactivity ◽  
Alumina Composites

Infrared Spectra and Differential-Thermal Analysis of Ceramic Glaze Frits

2019 ◽  
Vol 75 (9-10) ◽  
pp. 372-374
Author(s):  
K. Yu. Frolenkov ◽  
S. I. Matyukhin ◽  
L. Yu. Frolenkova
Keyword(s):  
Thermal Analysis ◽  
Differential Thermal Analysis ◽  
Infrared Spectra ◽  
Ceramic Glaze

Infrared spectra and thermal decompositions of metal acetates and dicarboxylates

1968 ◽  
Vol 46 (2) ◽  
pp. 257-265 ◽  
Author(s):  
K. C. Patil ◽  
G. V. Chandrashekhar ◽  
M. V. George ◽  
C. N. R. Rao
Keyword(s):  
Thermal Analysis ◽  
Thermal Decomposition ◽  
Differential Thermal Analysis ◽  
Rare Earth ◽  
Thermogravimetric Analysis ◽  
Infrared Spectra ◽  
Metal Acetate ◽  
Preliminary Results

The infrared spectra of rare earth acetates have been studied to examine the metal-acetate bonding. The thermal decomposition of rare earth acetates as well as lead and copper acetates have been investigated in detail by employing thermogravimetric analysis and differential thermal analysis. Thermal decomposition of calcium dicarboxylates (malonate to sebacate) have been studied employing t.g.a. and d.t.a. Infrared spectra of the dicarboxylates have also been studied. Preliminary results on the products of decomposition of dicarboxylates have been reported.

scholarly journals Characterisation of the surface structure and bioactivity of glass and glass ceramics using surface topography

2012 ◽  
Vol 10 (6) ◽  
pp. 1890-1898 ◽  
Author(s):  
Gabriela Lutišanová ◽  
Martin Palou ◽  
Milan Mikula ◽  
Jana Kozánková
Keyword(s):  
Surface Structure ◽  
Surface Topography ◽  
Body Fluid ◽  
Glass Ceramics ◽  
Apatite Layer ◽  
In Vitro Bioactivity ◽  
Ceramic Samples ◽  
Melting Technique ◽  
The Relationship

AbstractThe present paper reports the results of the relationship between the surface topography, microstructure and the in vitro bioactivity of samples with and without fluorapatite content in simulated body fluid. Glasses and glass ceramics belonging to the Li2O-SiO2-CaO-P2O5-CaF2 system were prepared by using conventional melting technique following by heat treatment to obtain glass ceramics. This current study demonstrates the benefits of combining two microscopic methods for better investigation of the surface structure. The formation of apatite layer on the surface and the increase in surface roughness proved that the glasses and glass ceramics with bioactive fluorapatite content could satisfy to the requirements for biomaterial applications. The results also showed that the roughness of apatite layer formed after immersion in body fluid on the surface of glasses with fluorapatite was more pronounced than that of equivalent glass ceramic samples cured under the same conditions.

Formulation and Characterization of Solid Dispersion Containing Capsaicin for the Treatment of Diabetes

2020 ◽  
Vol 15 (3) ◽  
pp. 219-225
Author(s):  
Tapan Kumar Giri ◽  
Payel Roy ◽  
Subhasis Maity
Keyword(s):  
Thermal Analysis ◽  
Differential Thermal Analysis ◽  
Animal Study ◽  
Solid Dispersion ◽  
Solid Dispersions ◽  
Aqueous Solubility ◽  
Peg 6000 ◽  
X Ray

Background: Chili peppers are widely used in many cuisines as a spice, and capsaicin is the main component. It has been reported that capsaicin acts as an antihyperglycemic agent. However, it shows poor aqueous solubility and bioavailability. Objective: The is to enhance the aqueous solubility and antihyperglycemic activity of capsaicin through solid dispersion formulation. Methods: Solid dispersions were prepared by the solvent evaporation method using polyethylene glycol 6000 (PEG 6000) as a hydrophilic carrier. Polymer-drug miscibility and drug crystallinity were characterized through the differential thermal analysis and X-ray powder patterns analysis. Solid dispersions were evaluated for solubility, in vitro drug dissolution and in vivo animal study in rats. Results: Results of x-ray powder patterns analysis showed a considerable reduction of drug crystallinity in solid dispersion. Differential thermal analysis result revealed a complete disappearance of capsaicin melting onset temperature in solid dispersion. From the phase solubility data, it was observed that the aqueous solubility of capsaicin was increased with increasing concentration of PEG 6000. Solid dispersion formulation showed considerable enhancement of in vitro release of drugs in comparison to pure capsaicin. In vivo animal study in rats shows that the solid dispersion containing capsaicin significantly reduced the blood glucose level in comparison to the free capsaicin. Conclusion: Higher anti-hyperglycemic effect of capsaicin loaded solid dispersion in comparison to the pure drug may be due to the enhancement of aqueous solubility of capsaicin. Thus, the solid dispersion of capsaicin showed a simple approach for capsaicin delivery with improved antidiabetic activity.

In Vitro Bioactivity Characterization of K-Mica-Fluorapatite Based Glass Ceramics Containing Varying Amount of TiO2 Addition

2006 ◽  
Vol 309-311 ◽  
pp. 321-324 ◽  
Author(s):  
Gültekin Göller ◽  
Ipek Akin ◽  
Niyazi Eruslu ◽  
E.S. Kayali
Keyword(s):  
Glass Ceramics ◽  
Weight Ratio ◽  
Xrd Analysis ◽  
Nucleating Agent ◽  
Ftir Analysis ◽  
Layer Formation ◽  
In Vitro Bioactivity ◽  
Second Stage

The purpose of this study is to investigate the crystallization behavior and in-vitro bioactivity character of glass ceramics having 3:7 weight ratio of flourapatite (Ca5(PO4)3F) to potassium mica (K2Mg3AlSi3O10F2) as a function of titania addition, and compare the morphology of hydroxycarbonateapatite (HCA) layer formation depending on titania addition on ceramic composition. It is observed from microstructural investigations that there is no morphology change occurred on precipitated HCA layer depending on nucleating agent in glass-ceramics. TF-XRD analysis indicates that after precipitation of initial particulates, crystallization proceeds and crystallization of precipitated HCA phase increases by increasing the time. It is observed that Ca, P ion variation in solution has two stage in terms of precipitation’ first stage represents formation of amorphous HCA and the second stage is related with crystallization. FTIR analysis strongly supports TF-XRD analysis as well.

Sintered Hydroxyapatite / Bioactive Glass Composites: Thermal Analysis and Bioactivity

2006 ◽  
Vol 309-311 ◽  
pp. 167-170 ◽  
Author(s):  
Xanthippi Chatzistavrou ◽  
K. Chrissafis ◽  
Eleana Kontonasaki ◽  
T. Zorba ◽  
Petros Koidis ◽  
...  
Keyword(s):  
Heat Treatment ◽  
Thermal Analysis ◽  
Differential Thermal Analysis ◽  
Treatment Process ◽  
Biological Properties ◽  
Heat Treatment Process ◽  
Layer Formation ◽  
Glass Composites ◽  
Sintered Composite ◽  
Composite Pellets

Three-dimensionally ordered materials containing hydroxyapatite (HAp) as well as Bioglass® (BG) have been prepared in form of pellets and have been examined the effects of BG addition -in combination with a heat treatment process- on biological properties of composite HAp/BG. The investigation of the bioactive behavior of sintered and unheated biphasic mixtures and the deviations from pure HAp was performed by FTIR spectroscopy and Differential Thermal Analysis. It was observed the appearance of new phases on sintered composite pellets, while a faster biological HAp layer formation was detected, on the composite unheated pellets’ surface than on pure HAp and sintered composite pellets, currently leading to increased bioactivity.

Effect of CeO2 Addition on In Vitro Bioactivity Properties of K-Mica-Fluorapatite Based Glass Ceramics

2007 ◽  
Vol 361-363 ◽  
pp. 261-264 ◽  
Author(s):  
Gultekin Goller ◽  
Ipek Akin
Keyword(s):  
Cerium Oxide ◽  
Crystallization Behavior ◽  
Glass Ceramics ◽  
Weight Ratio ◽  
Layer Formation ◽  
In Vitro Bioactivity ◽  
Oxide Addition

The aim of this study is to investigate the crystallization behavior and in-vitro bioactivity character of glass ceramics having 3:7 weight ratio of fluorapatite (Ca10(PO4)6F2) to potassium mica (K2Mg3AlSi3O10F2) as a function of cerium oxide addition, and compare the morphology of hydroxycarbonate apatite (HCA) layer formation depending on cerium oxide addition.

Equilibrium phases in the BeSO4-H2O system

1966 ◽  
Vol 19 (5) ◽  
pp. 751 ◽  
Author(s):  
IJ Bear ◽  
AG Turnbull
Keyword(s):  
Thermal Analysis ◽  
Phase Diagram ◽  
Solid Solution ◽  
Differential Thermal Analysis ◽  
Infrared Spectra ◽  
Kcal Mole ◽  
X Ray ◽  
Reversible Transitions ◽  
Equilibrium Phases

The equilibrium phases of the BeSO4-H2O system were studied by vapour hydration of BeSO4 and equilibration of thermally produced mixtures. Tetra-, di-, and mono-hydrate are the stable hydrates with no solid solution regions between them. X-ray and infrared spectra are presented for these hydrates and a provisional phase diagram drawn.��� Reversible transitions of BeS04 were found at 588° and 639°, the latter showing a hysteresis splitting of 4° on cooling. Transition heats of 1.2 ± 0.1 and 0.5 ± 0.1 kcal/mole respectively were found by differential thermal analysis.

scholarly journals Preparation and in Vitro Bioactivity of Micron-sized Bioactive Glass Particles Using Spray Drying Method

2018 ◽  
Vol 9 (1) ◽  
pp. 19 ◽  
Author(s):  
Yu-Jen Chou ◽  
Chih-Wei Hsiao ◽  
Nien-Ti Tsou ◽  
Meng-Huang Wu ◽  
Shao-Ju Shih
Keyword(s):  
Spray Drying ◽  
Glass Melting ◽  
Sol Gel ◽  
Synthetic Methods ◽  
Biological Applications ◽  
Drying Method ◽  
In Vitro Bioactivity ◽  
Bioactive Glasses ◽  
Spray Dried

In recent years, bioactive glasses (BGs) have attracted enormous attention with their superior bioactivity, non-toxicity and degradability. Owing to their properties, they have been applied in various biological applications. In the present work, we demonstrated that micron-sized BGs can be prepared with a spray drying method. This technique offers the advantages of low contamination and the ability of mass production, in contrast to the two major synthetic methods, conventional glass-melting and sol-gel, previously used for preparation of BGs. Characterizations of phase composition, morphology and specific surface area of spray dried BG powders were carried out and bioactivity was examined in vitro with respect to the ability to form a hydroxyapatite layer on the surface of the particles after they were immersed in simulated body fluid.

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