Synthesis and Characterization of a Novel Folate-Conjugated Themoresponsive Micelles

2012 ◽  
Vol 529 ◽  
pp. 555-559 ◽  
Author(s):  
Jing Jin ◽  
Jian Peng Xue ◽  
Si Si Cui ◽  
Jie Cao ◽  
Dong Yin Zhang ◽  
...  

In this study, a amphiphilic copolymer, poly ((N-isopropylacrylamide)-co-acrylamide-co- (octadecylacrylate)-co-(Falate-(polyethyleneglycol)-(acrylicacid)))(P(NIPA-co-AAm-co-ODA-co-FPA)) micelles was synthesized by free radical random copolymerization. The obtained amphiphilic copolymers were self-assembled into micelles, which exhibited thermally sensitivity. LCST of the micelles was detected by uv-vis spectrophotometer. The diameter and morphology of micelles were determined by laser particle size analyzer (LPSA) and transmittance electron microscope (TEM), respectively. The micelle with a diameter of 60 nm and LCST of 40 oC was obtained by utilizing of ODA and the feed ratio of NIPA and AAm, respectively, which is satisfied for drug delivery in living body. The maximum DLC was achieved with the amount of ODA (180mg).

2019 ◽  
Vol 12 (1) ◽  
pp. 13
Author(s):  
Dewi Lidiawati ◽  
Abdul Wahid Wahab ◽  
Abdul Karim

Gold nanoparticles have been successfully synthesized using beluntas leaf extract as reducing agents. This is indicated by the change of the color from yellow gold to purple solution after the addition of the beluntas leaf extract. The gold nanoparticles formed were observed for 92 hours using uv-vis and obtained stability after 72 hours with a wavelength about 545.50-546.00 nm. The size distribution of gold nanoparticles was determined using Particle Size Analyzer (PSA) with an average distribution of 101.6 nm. Based on the characterization using XRD, the diffraction pattern obtained at 2θ is 38.1077; 44,2935; 64,5155; 77,4862 which show the presence of gold nanoparticles. Furthermore, it was characterized using SEM EDX showed that the average shape of gold nanoparticles was spherical with a composition ofAu 48%, C 43.33%, and several other elements around 8.67%.


2018 ◽  
Vol 3 (1) ◽  
pp. 12 ◽  
Author(s):  
Zaimahwati Zaimahwati ◽  
Yuniati Yuniati ◽  
Ramzi Jalal ◽  
Syahman Zhafiri ◽  
Yuli Yetri

<p>Pada penelitian ini telah dilakukan isolasi dan karakterisasi bentonit alam menjadi nanopartikel montmorillonit. Bentonit alam yang digunakan diambil dari desa Blangdalam, Kecamatan Nisam Kabupaten Aceh Utara.  Proses isolasi meliputi proses pelarutan dengan aquades, ultrasonic dan proses sedimentasi. Untuk mengetahui karakterisasi montmorillonit dilakukan uji FT-IR, X-RD dan uji morfologi permukaan dengan Scanning Electron Microscopy (SEM). Partikel size analyzer untuk menganalisis dan menentukan ukuran nanopartikel dari isolasi bentonit alam. Dari hasil penelitian didapat ukuran nanopartikel montmorillonit hasil isolasi dari bentonit alam diperoleh berdiameter rata-rata 82,15 nm.</p><p><em>In this research we have isolated and characterized natural bentonite into montmorillonite nanoparticles. Natural bentonite used was taken from Blangdalam village, Nisam sub-district, North Aceh district. The isolation process includes dissolving process with aquades, ultrasonic and sedimentation processes.  The characterization of montmorillonite, FT-IR, X-RD and surface morphology test by Scanning Electron Microscopy (SEM). Particle size analyzer to analyze and determine the size of nanoparticles from natural bentonite insulation. From the research results obtained the size of montmorillonite nanoparticles isolated from natural bentonite obtained an average diameter of 82.15 nm.</em></p>


RSC Advances ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 1952-1959
Author(s):  
Yi Zhao ◽  
Fangfang Peng ◽  
Yangchuan Ke

Emulsion with small particle size and good stability stabilized by emulsifiers was successfully prepared for EOR application.


RSC Advances ◽  
2021 ◽  
Vol 11 (16) ◽  
pp. 9076-9085
Author(s):  
Kanchan Yadav ◽  
Megha Das ◽  
Nurul Hassan ◽  
Archana Mishra ◽  
Jayeeta Lahiri ◽  
...  

A novel nanodot-using protein has been synthesized for the live cell imaging and drug delivery of melatonin in breast cancer cells. Its unique properties hold potential for various biomedical applications in the field of bioimaging and drug delivery.


2020 ◽  
Vol 21 (8) ◽  
pp. 3332-3341 ◽  
Author(s):  
Richard M. England ◽  
Jennifer I. Moss ◽  
Anders Gunnarsson ◽  
Jeremy S. Parker ◽  
Marianne B. Ashford

Polymer ◽  
2000 ◽  
Vol 41 (3) ◽  
pp. 821-826 ◽  
Author(s):  
M.G. Garcı́a-Martı́n ◽  
C. Jiménez-Hidalgo ◽  
S.S.J. Al-Kass ◽  
I. Caraballo ◽  
M.V. de Paz ◽  
...  

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