Microstructure and Controllable Degradation of Bioglass Reinforced Calcium Phosphate Scaffolds

2007 ◽  
Vol 280-283 ◽  
pp. 1599-1604
Author(s):  
Kai Hui Nan ◽  
Ying Jun Wang ◽  
Xiao Feng Chen ◽  
Na Ru Zhao ◽  
L.Y. Wang
Keyword(s):  
Body Fluid ◽  
Carbonate Apatite ◽  
Plasma Spectroscopy ◽  
Reaction Products ◽  
X Ray Diffraction ◽  
Oriented Growth ◽  
X Ray ◽  
Fourier Transformed Infrared Spectroscopy ◽  
Controllable Degradation ◽  
Hydroxy Carbonate

A porous bioglass reinforced tricalcium phosphate scaffold was prepared. The microstructure, degradability and reaction products of the scaffold after immersed in a simulated body fluid for different days were emphatically investigated using scanning electron microscopy, energy-dispersive X-ray analysis, X-ray diffraction, Fourier transformed infrared spectroscopy and induced coupled plasma spectroscopy. The results showed that a homogeneous hydroxy-carbonate-apatite (HCA) layer forms on the surface of the scaffold for over 30- day immersion and the oriented growth of the HCA occurs. In addition, this paper discussed the competing mechanism between the dissolution and the precipitation via the measurement of calcium and silicon ionic concentrations in the SBF.

Fabrication and Characterization of Bioactive Composite Scaffolds Based on β-TCP-BG-PLA for Bone Tissue Engineering

2007 ◽  
Vol 330-332 ◽  
pp. 919-922 ◽  
Author(s):  
Na Ru Zhao ◽  
Ying Jun Wang ◽  
Xiao Feng Chen ◽  
Cheng Yun Ning
Keyword(s):  
Body Fluid ◽  
Poly Lactic Acid ◽  
Plasma Spectroscopy ◽  
Reaction Products ◽  
X Ray Diffraction ◽  
X Ray ◽  
Fourier Transformed Infrared Spectroscopy ◽  
Ft Ir ◽  
Bioactive Composites

In this study, the bioactive composites based on β-tricalcium phosphate (β-TCP), bioglass (BG) and poly lactic acid (PLA) were prepared. The microstructure, degradability and reaction products of the scaffold soaked in a simulated body fluid (SBF) at 36.5°C for different days were characterized through scanning electron microscopy (SEM), energy-dispersive X-ray analysis (EDS), X-ray diffraction (XRD), Fourier transformed infrared spectroscopy (FT-IR) and induced coupled plasma spectroscopy (ICP). The weight loss and strength decrease with the time were tested. The results showed that at the same porosity, the degradability of the scaffold samples decreased as followed: β-TCP/BG/PLA>β－TCP/BG>β－TCP.The materials had highly bioactive response ability to the Simulate Body Fluid (SBF) and promptly induced a bone like HA layer on the surface of the scaffolds when immersed in the SBF.

In Vitro Study of Microplasma Sprayed Hydroxyapatite Coatings in Simulated Body Fluid

2009 ◽  
Vol 79-82 ◽  
pp. 815-818 ◽  
Author(s):  
Qiu Ying Zhao ◽  
Ding Yong He ◽  
Xiao Yan Li ◽  
Jian Min Jiang
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
Carbonate Apatite ◽  
In Vitro Test ◽  
X Ray Diffraction ◽  
X Ray ◽  
Amorphous Phases ◽  
Hydroxyapatite Coatings ◽  
Vitro Test

Hydroxyapatite (HA) coatings were deposited onto Ti6Al4V substrate by microplasma spraying (MPS) in the current research. The morphology, phase compositions, and percentage of crystallinity of the coatings were characterized by means of scanning electron microscopy (SEM) and X-ray diffraction. An in vitro evaluation by soaking the coatings in simulated body fluid (SBF) for up to 14 days was conducted aiming at the evaluation of their bioactivity. Results from the present investigation suggest that microplasma sprayed HA coatings exhibited certain roughness, pores, and microcracks. Thermal decomposition existed in the coatings where HA, α-TCP，β-TCP, amorphous phases, and CaO-exclusive impurities were observed. The in vitro test indicated that HA coatings deposited by MPS possessed better bioactivity and stability. A layer of carbonate-apatite covered most of the coating surface, which did not exhibit significant spalling after incubation in SBF.

scholarly journals Contrasting In Vitro Apatite Growth from Bioactive Glass Surfaces with that of Spontaneous Precipitation

Materials ◽  
2018 ◽  
Vol 11 (9) ◽  
pp. 1690 ◽  
Author(s):  
Yang Yu ◽  
Zoltán Bacsik ◽  
Mattias Edén
Keyword(s):  
Body Fluid ◽  
Carbonate Apatite ◽  
X Ray Diffraction ◽  
Bioactive Glasses ◽  
Direct Precipitation ◽  
Living Tissues ◽  
Glass Surfaces ◽  
Supersaturated Solutions ◽  
Hydroxy Carbonate

Body-fluid-exposed bioactive glasses (BGs) integrate with living tissues due to the formation of a biomimetic surface layer of calcium hydroxy-carbonate apatite (HCA) with a close composition to bone mineral. Vast efforts have been spent to understand the mechanisms underlying in vitro apatite mineralization, as either formed by direct precipitation from supersaturated solutions, or from BG substrates in a simulated body fluid (SBF). Formally, these two scenarios are distinct and have hitherto been discussed as such. Herein, we contrast them and identify several shared features. We monitored the formation of amorphous calcium phosphate (ACP) and its crystallization into HCA from a Na 2 O–CaO–SiO 2 –P 2 O 5 glass exposed to SBF for variable periods out to 28 days. The HCA growth was assessed semi-quantitatively by Fourier transform infrared spectroscopy and powder X-ray diffraction, with the evolution of the relative apatite content for increasing SBF-exposure periods evaluated against trends in Ca and P concentrations in the accompanying solutions. This revealed a sigmoidal apatite growth behavior, well-known to apply to spontaneously precipitated apatite. The results are discussed in relation to the prevailing mechanism proposed for in vitro HCA formation from silicate-based BGs, where we highlight largely simultaneous growth processes of ACP and HCA.

scholarly journals Structural Properties of Nanostructured Carbonate Apatites

2008 ◽  
Vol 396-398 ◽  
pp. 611-614 ◽  
Author(s):  
C.A.O. Ramirez ◽  
Andrea Machado Costa ◽  
J. Bettini ◽  
Antonio J. Ramirez ◽  
Marcelo Henrique Prado da Silva ◽  
...  
Keyword(s):  
Carbonate Apatite ◽  
Ftir Analysis ◽  
X Ray Diffraction ◽  
Wet Chemical Method ◽  
Apatite Phase ◽  
X Ray ◽  
Fourier Transformed Infrared Spectroscopy ◽  
Transmission Electron ◽  
Second Phases ◽  
Wet Chemical

B-type carbonate apatite samples were synthesized by wet chemical method and characterized by X-ray Fluorescence Spectrometry, X-ray Diffraction, Fourier Transformed Infrared Spectroscopy and High Resolution Transmission Electron Microscopy. The XRD and FTIR analysis confirmed the presence of one B-type carbonate apatite phase and the HRTEM images revealed the coexistence of amorphous and polycrystalline regions in the order of 2nm with the carbonate apatite structure. Second phases or precursors were not discovered.

A study on using expanded perlite with hydroxyapatite: Reinforced bio-composites

2021 ◽  
pp. 095441192199656
Author(s):  
Erdoğan Karip ◽  
Mehtap Muratoğlu
Keyword(s):  
Body Fluid ◽  
Xrd Analysis ◽  
Cold Isostatic Pressing ◽  
Expanded Perlite ◽  
X Ray Diffraction ◽  
Pressing Method ◽  
X Ray ◽  
Infra Red ◽  
Ft Ir

People are exposed to different kinds of diseases or various accidents in life. Hydroxyapatite (HA) has been widely employed for bone treatment applications. In this study, HA was extracted from sheep bones. Bio-composites were doped with 1, 5, and 10 wt.% of expanded perlite and 5 wt.% of ZrO2–MgO-P2O5. The bio-composites were prepared by the cold isostatic pressing method (250 MPa) and sintered at 900°C for 1 h. In order to evaluate the characteristics of the bio-composites, microhardness, density, X-ray diffraction (XRD), Fourier transform infra-red spectroscopy (FT-IR), scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS) analyses were carried out on them. Additionally, the specimens whose characteristics were determined were kept in synthetic body fluid (SBF), and their in vitro behavior was examined. As a result, it was observed that microhardness increased as both the weight and the grain size of the expanded perlite were increased. Calcium silicate, tri-calcium phosphate, and hydroxyapatite were observed in the XRD analysis of all samples, and the formation of apatite structures was increased by addition of ZrO2–MgO–P2O5.

THE STUDY ON GRANTING BIOACTIVITY OF Ti ALLOY BY SURFACE TREATMENT

2010 ◽  
Vol 17 (02) ◽  
pp. 153-157 ◽  
Author(s):  
N. R. HA ◽  
Z. X. YANG ◽  
G. C. KIM ◽  
K. H. HWANG ◽  
D. S. SEO ◽  
...  
Keyword(s):  
Surface Treatment ◽  
Body Fluid ◽  
Surface Effect ◽  
In Vitro Test ◽  
Ti Alloy ◽  
X Ray Diffraction ◽  
X Ray ◽  
Chemical Surface ◽  
Vitro Test

Titanium alloys are superior of biocompatibility, mechanical properties and chemical stability. The biocompatibility of Ti alloy is related to the surface effect between human tissue and implant. Therefore, the purpose of this study is to investigate the bioactivity of Ti alloy by alkali and acid chemical surface treatment; and the biocompatibility of Ti alloy was evaluated by in vitro test. Higher bone-bonding ability and bioactivity of the substrate were obtained by the formation of apatite layers on the Ti alloy in simulated body fluid. The microstructures of apatite layer were investigated by scanning electron microscope (SEM) and the formed phases were analyzed with X-ray diffraction (XRD).

scholarly journals Enhanced apatite precipitation on a biopolymer-coated bioactive glass

2015 ◽  
Vol 1 (1) ◽  
Author(s):  
M. Araújo ◽  
M. Miola ◽  
A. Venturello ◽  
G. Baldi ◽  
J. Perez ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Body Fluid ◽  
Organic Coating ◽  
Medical Applications ◽  
Sintering Process ◽  
X Ray Diffraction ◽  
Ph Measurements ◽  
X Ray ◽  
Ft Ir ◽  
Scanning Electron

AbstractIn this work, sintered pellets of a silica-based bioactive glass were dip-coated with a biocompatible natural-derived polymer in order to investigate the influence of the organic coating on the glass bioactivity. After the sintering process optimization, uncoated and coated pellets have been characterized by means of scanning electron microscopy with energy dispersive spectroscopy (SEM, EDS), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR) and pH measurements, after the immersion in a simulated body fluid (SBF). An increased apatite forming ability and a better control of the pH during soaking of the samples in SBF were observed in the presence of the biopolymer. This result opens a new insight on the simple fabrication of highly bioactive hybrid inorganic-organic materials for medical applications.

scholarly journals Study on the Catalytic Effect of Nitric Acid Activated Myanmar Natural Clay for the Degradation of Plastic Wastes

2018 ◽  
Vol 3 (8) ◽  
pp. 56
Author(s):  
Amie Thant ◽  
Chaw Su Su Hmwe
Keyword(s):  
Nitric Acid ◽  
Catalyst Support ◽  
Natural Clay ◽  
X Ray Diffraction ◽  
X Ray ◽  
Fourier Transformed Infrared Spectroscopy ◽  
Physico Chemical ◽  
Plastic Wastes ◽  
Pyrolytic Oil ◽  
Liquid Yield

In this study, the performance of different acid treated Myanmar Natural Clay (Mabisian) was conducted the pyrolysis of mixed plastic wastes, 40% high density polyethylene, 30% polypropylene, 25% low density polyethylene and 5% polystyrene. Mabisian clay was refluxed with different concentration of nitric acid (2M, 4M, 6M, 8M, 10M, 12M and 14M)  at 100ºC for 3hrs followed by calcination at 500ºC for 1hr. The physico-chemical characteristics of resulted leached clay were studied by X-Ray Fluoresence spectroscopy (XRF), X-Ray Diffraction (XRD) and Fourier Transformed Infrared Spectroscopy (FTIR). The pyrolytic oil was characterized by Gas Chromatography – mass spectopy (GC-MS). XRF and FTIR studies indicated that acid treatment under reflux condition lead to the removal of octahedral Al3+ cations along with other impurities.  The chemical treatment increased the Si/Al ratio.  The maximum liquid yield (75%) was obtained at 12 M nitric acid, 3hr reaction time and 100 º C reaction temperatures. In addition, the percent peak area of gasoline range hydrocarbon was obtained 55.6% at optimum condition. Thus, the treated clay can be used as promising as catalyst support.

Improvement of Anti-Washout Performance of Calcium Phosphate Cement Using Modified Starch

2007 ◽  
Vol 336-338 ◽  
pp. 1628-1631 ◽  
Author(s):  
Ling Chen ◽  
Hong Xiang ◽  
Xiao Xi Li ◽  
Jian Dong Ye ◽  
Xiu Peng Wang ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Body Fluid ◽  
Clinical Applications ◽  
Modified Starch ◽  
X Ray Diffraction ◽  
X Ray ◽  
Calcium Phosphate Cements ◽  
Modified Starches ◽  
Gelatinized Starch ◽  
Bone Repairing

Calcium phosphate cements (CPCs) are well-known orthopedic materials for filling bone. However, CPC pastes tend to disintegrate immediately when contacting with blood or other aqueous (body) fluids, which is a main limitation of its clinical applications in bone repairing, reconstruction and augmentation. To improve the anti-washout performance of CPC, modified starches such as pre-gelatinized starch, etherified starch, and esterified starch were added to the liquid phase of CPC in this work. CPC with good anti-washout performance was prepared and the effects of the modified starches on the properties of CPC were investigated. The results showed that the CPC with the modified starches were more stable in simulated body fluid than that without modified starch, especially the CPC with the etherified starch (II). X-ray diffraction analysis revealed that the modified starches did not inhibit CPC components from converting to hydroxyapatite. Furthermore, the anti-washout mechanism of the modified starches in CPC was discussed. It is concluded that the addition of the modified starches such as pre-gelatinized starch, etherified starch, and esterified starch to CPC can improve its anti-washout performance and should be of value in clinical surgery where the cement is exposed to blood.

Effect of Different Solutions on Hydrothermal Treatment of β-Tricalcium Phosphate Scaffold

2017 ◽  
Vol 264 ◽  
pp. 66-69
Author(s):  
Fadilah Darus ◽  
Mariatti Jaafar
Keyword(s):  
Hydrothermal Treatment ◽  
Sodium Hydrogen Carbonate ◽  
Surface Characteristics ◽  
Carbonate Apatite ◽  
X Ray Diffraction ◽  
Xrd Pattern ◽  
X Ray ◽  
Sodium Hydrogen ◽  
Hydrogen Carbonate ◽  
Before And After

Carbonate apatite would be ideal for bone substitute due to its composition of 4-8% carbonate similar to bone mineral. The purpose of the present study was to produce carbonate apatite scaffold by using hydrothermal treatment of β-TCP scaffold as a precursor. The effect of different solutions on hydrothermal treatment was studied. The microstructure of scaffold before and after hydrothermal were characterized by scanning electron microscopy (SEM). It is observed that surface characteristics are governed by the types of immersion solution. The typical smooth surface of the β-TCP scaffold was observed before hydrothermal. Different morphology was observed after hydrothermal in different solutions. X-Ray Diffraction (XRD) pattern indicates that the peak of apatite with low intensities present after hydrothermal treatment in sodium hydrogen carbonate solution.

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