Chemicovector Effect of Nano-Size-Hydroxyapatite Doped YSZ Ceramics on Apatite Formability in SBF
To produce ceramics with high mechanical strength and bioactivity, we developed the little amount of nano-sized hydroxyapatite (HA)-doped zirconia composite ceramics (nanoHA-Z). The bioactivity of the nanoHA-Z was studied by in vitro estimation with simulated body fluid (SBF). Scanning electron microscopy observation showed deposited bone-like apatite layer entire covering the surface of nanoHA-Z ceramics in SBF. The enhanced apatite formability was attributed to higher Ca and PO4 concentrations in the vicinities of the nanoHA-Z surfaces due to the dissolution of the β-tricalcium phosphate decomposed from the added HA. Utilization of Chemicovector effect was proved to be one of the powerful approaches for improvement method of biomaterials.