Effect of Joule Heat on Hydrophily of Microchannel

2014 ◽  
Vol 609-610 ◽  
pp. 606-610
Author(s):  
Xiao Wei Han ◽  
Xiao Wei Liu ◽  
Li Tian ◽  
He Zhang ◽  
Yao Liu ◽  
...  
Keyword(s):  
Transfer Coefficient ◽  
Polymethyl Methacrylate ◽  
Microfluidic Chip ◽  
Room Temperature ◽  
Joule Heat ◽  
Microfluidic Chips ◽  
Interior Surface

We discuss the effect of joule heat which comes from eletroosmosis flow on the microfluidic chip. Our microfluidic chips are fabricated from polymethyl methacrylate (PMMA). As everyone knows, PMMA is a poor conductor of heat, and its transfer coefficient is only 0.19W/m·K in room temperature. So, the heat is generated by eletroosmosis canʼt conduct outside the microchannels of microfluidic chip easily. We research the effect joule heat on walls of microchannels which are made of PMMA. During our study, interior surface of microchannelsʼ hydrophobicity is changed by effect of joule heat.

A Novel Room-Temperature Bonding Method Based on Electrohydrodynamic Printing

2021 ◽  
Vol 21 (3) ◽  
pp. 1672-1677
Author(s):  
Wenzheng Wu ◽  
Xue Yang ◽  
Rui Liu ◽  
Zhifu Yin ◽  
D. F. Wang ◽  
...  
Keyword(s):  
Microfluidic Chip ◽  
Silicon Substrate ◽  
Bonding Strength ◽  
Room Temperature ◽  
Production Efficiency ◽  
Microfluidic Chips ◽  
Electrohydrodynamic Printing ◽  
Inner Diameter ◽  
Bonding Method

Microfluidic chips made by traditional materials (glass and silicon) are still important for fluorescence tests, biocompatible experiments, and high temperature applications. However, the majority of the present bonding methods suffer from ultra-clean requirement, complicated fabrication process, and low production efficiency. In the present work, an Electrohydrodynamic printing assist bonding method was proposed. By this method, the ultraviolet-cured-glue dots were printed onto the silicon substrate, and then the patterned glass and silicon substrate can be bonded together at room temperature. The influence of printing condition (nozzle inner-diameter, applied voltage, printing height, and flow rate) on the diameter of printed dot was analyzed by experiments. By the optimized printing condition, the glass-silicon microfluidic chip can be well bonded. The bonding strength and leakage test demonstrated the high bonding quality of the microfluidic chip (bonding strength of 28 MPa and leakage pressure of 3.5 MPa).

A NOVEL METHOD FOR RAPID FABRICATION OF PMMA MICROFLUIDIC CHIP BY LASER CUTTING AND SEALING INTEGRATION

2019 ◽  
Vol 26 (08) ◽  
pp. 1950042 ◽  
Author(s):  
XUEYE CHEN ◽  
TIECHUAN LI ◽  
QI GAO
Keyword(s):  
Polymethyl Methacrylate ◽  
Microfluidic Chip ◽  
Laser Cutting ◽  
Cost Effective ◽  
Cover Plate ◽  
Microfluidic Chips ◽  
Pmma Substrate ◽  
Rapid Fabrication ◽  
Novel Method ◽  
Liquid Pools

In this paper, we present a new method that is capable of manufacturing microfluidic chips of polymethyl methacrylate (PMMA) rapidly and cheaply. This technique, which we call Tape adhering-Laser Cutting and Sealing Integration (TLCSI), only utilizes a CO2 laser and a piece of double-sided tape to produce a microfluidic chip in several minutes. It only has three main steps. First, the double-sided tape sticks to the surface of a PMMA substrate. Second, the microchannel should be cut on the surface of the double-sided tape. At last, a PMMA cover plate with liquid pools is pressed onto the surface of the double-sided tape and a CO2 laser is used to cut edges of the chip for sealing the chip. We present a qualified microfluidic chip with regular microchannels and sealing strength of 1.2[Formula: see text]Mpa. Compared with most current fabrication methods, TLCSI is a quick and cost-effective way to produce microfluidic chips of PMMA.

Heating Carve Technique for Polymer Microfluidic Microchannel

2012 ◽  
Vol 503 ◽  
pp. 103-107
Author(s):  
Xiao Wei Han ◽  
Wei Wang ◽  
G.H. Ye ◽  
Xiao Wei Liu ◽  
Li Tian ◽  
...  
Keyword(s):  
Polymethyl Methacrylate ◽  
Microfluidic Chip ◽  
Mass Production ◽  
Hot Embossing ◽  
Direct Write ◽  
Microfluidic Chips ◽  
Movement Velocity ◽  
Laser Direct Write

A new manufacture mainly for polymethyl methacrylate (PMMA) microfluidic chips is presented in this paper. In this technique, polymer microfluidic microchannels were fabricated by microcutter which temperature is controlled and stabilized by PID methord. There are so many techniques, such as hot embossing, laser direct-write, for mass-production of polymer microfluidic chip. However, we may feel different kinds of shortages when we use these techniques. In this paper, the experiment result shows that microcutter’s movement velocity and temperature have effert on microfluidic microchannel’s roughness.

Study on the Manufacture of Microfluidic Chip with Coated Glass

2012 ◽  
Vol 548 ◽  
pp. 254-257 ◽  
Author(s):  
Yan He ◽  
Bai Ling Huang ◽  
Yong Lai Zhang ◽  
Li Gang Niu
Keyword(s):  
Microfluidic Chip ◽  
Low Cost ◽  
Microfluidic Channel ◽  
Critical Factor ◽  
Wet Etching ◽  
Microfluidic Chips ◽  
Etching Technique ◽  
Chip Quality ◽  
Wet Chemical ◽  
Wet Chemical Etching

In this paper, a simple and facile technique for manufacturing glass-based microfluidic chips was developed. Instead of using expensive dry etching technology, the standard UV lithography and wet chemical etching technique was used to fabricate microchannels on a K9 glass substrate. The fabrication process of microfluidic chip including vacuum evaporation, annealing, lithography, and BHF (HF-NH4F-H2O) wet etching were investigated. Through series experiments, we found that anneal was the critical factor for chip quality. As a representative example, a microfluidic channel with 20 m of depth, and 80 m of width was successfully prepared, and the channel surfaces are quite smooth. These results present a simple, low cost, flexible and easy way to fabricate glass-based microfluidic chips.

Plug-and-play polymer microfluidic chips for hydrated, room temperature, fixed-target serial crystallography

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Deepshika Gilbile ◽  
Megan L. Shelby ◽  
Artem Y. Lyubimov ◽  
Jennifer L. Wierman ◽  
Diana C. F. Monteiro ◽  
...  
Keyword(s):  
Room Temperature ◽  
Microfluidic Chips ◽  
Fixed Target ◽  
Plug And Play ◽  
X Ray ◽  
X Ray Crystallography ◽  
Serial Crystallography

This work presents our development of versatile, inexpensive, and robust polymer microfluidic chips for routine and reliable room temperature serial X-ray crystallography measurements.

A STUDY ON THE SURFACE QUALITIES OF FOUR POLYMER SUBSTRATE MICROCHANNELS USING CO2 LASER FOR MICROFLUIDIC CHIP

2019 ◽  
Vol 26 (03) ◽  
pp. 1850160
Author(s):  
ZENGLIANG HU ◽  
XUEYE CHEN ◽  
YI REN
Keyword(s):  
Polyethylene Terephthalate ◽  
Polymethyl Methacrylate ◽  
Microfluidic Chip ◽  
Laser Power ◽  
Laser Cutting ◽  
Cutting Speed ◽  
Processing Parameters ◽  
Polymer Substrate ◽  
Laser Machine ◽  
Polymer Substrates

The paper demonstrates four different polymer substrate microchannels are fabricated by CO2 laser machine. The four different polymer substrates are Polymethyl-methacrylate (PMMA), Polycarbonate (PC), Polystyrene (PS) and Polyethylene Terephthalate (PET), respectively. A number of microchannels are obtained and all roughness is measured. The four different polymer substrate microchannels are processed with different processing parameters. Laser power is set from 4[Formula: see text]W to 32[Formula: see text]W and laser cutting speed is set from 5[Formula: see text]mm/s to 30[Formula: see text]mm/s. The results show the roughness of PS substrate microchannel is lower than that of other three polymer substrate microchannels at the same parameters. When laser power is below 4[Formula: see text]W, the roughness of four polymer substrates are similar. The roughness of different polymer substrate microchannels decreases with the increase of laser power. The roughness of different polymer substrate microchannels also happens to change with increase of laser cutting speed.

Reactively sputtered half-metallic Fe3O4 thin films at room temperature on polymethyl methacrylate: A perspective for flexible spintronics

2020 ◽  
Vol 46 (11) ◽  
pp. 19302-19310
Author(s):  
Mohammad Shahnawaze Ansari ◽  
Mohd Hafiz Dzarfan Othman ◽  
Mohammad Omaish Ansari ◽  
Sana Ansari ◽  
Huda Abdullah
Keyword(s):  
Thin Films ◽  
Polymethyl Methacrylate ◽  
Room Temperature ◽  
Half Metallic

Design and Fabrication of Micro Hot Embossing Mold for Microfluidic Chip Used in Flow Cytometry

2007 ◽  
Vol 339 ◽  
pp. 246-251
Author(s):  
L.Q. Du ◽  
C. Liu ◽  
H.J. Liu ◽  
J. Qin ◽  
N. Li ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Microfluidic Chip ◽  
Low Cost ◽  
Hot Embossing ◽  
Microfluidic Chips ◽  
Metal Mold ◽  
Nickel Electroforming ◽  
Thick Photoresist ◽  
Nickel Base ◽  
Microfabrication Technology

Micro hot embossing mold of microfluidic chip used in flow cytometry is designed and microfabricated. After some kinds of microfabrication processes are tried, this paper presents a novel microfabrication technology of micro hot embossing metal mold. Micro metal mold is fabricated by low-cost UV-LIGA surface micro fabrication process using negative thick photoresist, SU-8. Different from other micro hot embossing molds, the micro mold with vertical sidewalls is fabricated by micro nickel electroforming directly on Nickel base. Based on the micro Nickel mold and automation fabrication system, high precision and mass-producing microfluidic chips have been fabricated and they have been used in flow cytometry

Surface Microfabrication of Conventional Glass Using Femtosecond Laser for Microfluidic Applications

2017 ◽  
Vol 11 (6) ◽  
pp. 878-882 ◽  
Author(s):  
Takuma Niioka ◽  
◽  
Yasutaka Hanada
Keyword(s):  
High Resolution ◽  
Microfluidic Chip ◽  
High Speed ◽  
Single Cell Analysis ◽  
Glass Slide ◽  
Cell Analysis ◽  
Microfluidic Chips ◽  
Direct Writing ◽  
Laser Direct Writing ◽  
Fs Laser

Recently, a lot of attention has been paid to a single-cell analysis using microfluidic chips, since each cell is known to have several different characteristics. The microfluidic chip manipulates cells and performs high-speed and high-resolution analysis. In the meanwhile, femtosecond (fs) laser has become a versatile tool for the fabrication of microfluidic chips because the laser can modify internal volume solely at the focal area, resulting in three-dimensional (3D) microfabrication of glass materials. However, little research on surface microfabrication of materials using an fs laser has been conducted. Therefore, in this study, we demonstrate the surface microfabrication of a conventional glass slide using fs laser direct-writing for microfluidic applications. The fs laser modification, with successive wet etching using a diluted hydrofluoric (HF) acid solution, followed by annealing, results in rapid prototyping of microfluidics on a conventional glass slide for fluorescent microscopic cell analysis. Fundamental characteristics of the laser-irradiated regions in each experimental procedure were investigated. In addition, we developed a novel technique combining the fs laser direct-writing and the HF etching for high-speed and high-resolution microfabrication of the glass. After establishing the fs laser surface microfabrication technique, a 3D microfluidic chip was made by bonding the fabricated glass microfluidic chip with a polydimethylsiloxane (PDMS) polymer substrate for clear fluorescent microscopic observation in the microfluidics.

Sign in / Sign up

Export Citation Format

Share Document