To the Theory of Hyperthermia Effect Induced by Magnetic Nanoparticles

2015 ◽  
Vol 233-234 ◽  
pp. 771-775 ◽  
Author(s):  
Andrey Zubarev ◽  
Ali Abu-Bakr

In this paper, we present results of theoretical modeling of the rise of temperature for the unit of time in a dilute suspension of the fiber ferromagnetic particles under the action of the linearly polarized oscillating magnetic field. Two mechanisms of the heat production, namely the particle rotation in the liquid and its internal remagnetization are considered. We study effect of the particle shape, its magnetic properties and rheological properties of the carrier liquid on the rise of temperature for the unit of time by the particles.

2020 ◽  
Vol 515 ◽  
pp. 167306 ◽  
Author(s):  
Hao-jia Wu ◽  
Wei Wang ◽  
Dan Lv ◽  
Chun-lu Chang ◽  
Bo-chen Li ◽  
...  

2019 ◽  
Vol 5 (3) ◽  
pp. 42 ◽  
Author(s):  
Muhammad Bilal ◽  
Shahid Mehmood ◽  
Tahir Rasheed ◽  
Hafiz M. N. Iqbal

In recent years, magnetic nanoparticles (MNPs) have gained increasing attention as versatile carriers because of their unique magnetic properties, biocatalytic functionalities, and capabilities to work at the cellular and molecular level of biological interactions. Moreover, owing to their exceptional functional properties, such as large surface area, large surface-to-volume ratio, and mobility and high mass transference, MNPs have been employed in several applications in different sectors such as supporting matrices for enzymes immobilization and controlled release of drugs in biomedicine. Unlike non-magnetic carriers, MNPs can be easily separated and recovered using an external magnetic field. In addition to their biocompatible microenvironment, the application of MNPs represents a remarkable green chemistry approach. Herein, we focused on state-of-the-art two majorly studied perspectives of MNPs as versatile carriers for (1) matrices for enzymes immobilization, and (2) matrices for controlled drug delivery. Specifically, from the applied perspectives of magnetic nanoparticles, a series of different applications with suitable examples are discussed in detail. The second half is focused on different metal-based magnetic nanoparticles and their exploitation for biomedical purposes.


2016 ◽  
Vol 251 ◽  
pp. 3-7 ◽  
Author(s):  
Egidijus Dragašius ◽  
Evguenia Korobko ◽  
Zoya Novikava ◽  
Elena Sermyazhko

Mechanical properties of polymer composite materials, containing ferromagnetic small dispersed particles of carbonyl iron that create structures along force lines of the magnetic field have been investigated. In paper the influence of the polymer matrix material and the orientation of ferromagnetic particles inside it on the properties of polymer composites are considered in the regimes of horizontal shear, vertical shear and periodical (sinusoidal) deformation of the samples. Magnetic properties at the change of magnetic field induction B in the range of 0 to 1 T are determined.


Nanomaterials ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3240
Author(s):  
Michael Zeinoun ◽  
Javier Domingo-Diez ◽  
Miguel Rodriguez-Garcia ◽  
Oscar Garcia ◽  
Miroslav Vasic ◽  
...  

For decades now, conventional sinusoidal signals have been exclusively used in magnetic hyperthermia as the only alternating magnetic field waveform to excite magnetic nanoparticles. However, there are no theoretical nor experimental reasons that prevent the use of different waveforms. The only justifiable motive behind using the sinusoidal signal is its availability and the facility to produce it. Following the development of a configurable alternating magnetic field generator, we aim to study the effect of various waveforms on the heat production effectiveness of magnetic nanoparticles, seeking to prove that signals with more significant slope values, such as the trapezoidal and almost-square signals, allow the nanoparticles to reach higher efficiency in heat generation. Furthermore, we seek to point out that the nanoparticle power dissipation is dependent on the waveform’s slope and not only the frequency, magnetic field intensity and the nanoparticle size. The experimental results showed a remarkably higher heat production performance of the nanoparticles when exposed to trapezoidal and almost-square signals than conventional sinusoidal signals. We conclude that the nanoparticles respond better to the trapezoidal and almost-square signals. On the other hand, the experimental results were used to calculate the normalized power dissipation value and prove its dependency on the slope. However, adjustments are necessary to the coil before proceeding with in vitro and in vivo studies to handle the magnetic fields required.


2021 ◽  
Vol 931 (1) ◽  
pp. 012011
Author(s):  
VN Kuryakov ◽  
I V Sergeev ◽  
O O Efanova ◽  
O K Zheludkova

Abstract This work presents the results of studies of a series of samples of aqueous dispersions of magnetic nanoparticles. The particle sizes were measured for these samples by the dynamic scattering method. Using the method of ultramicroscopy, the number concentration of particles in the samples and the concentration of particles remaining in the volume of the samples after exposure to a magnetic field at various time intervals were measured.


2020 ◽  
Vol 8 (A) ◽  
pp. 24-36
Author(s):  
Mark Christopher Arokiaraj ◽  
Aleksandr Liubimtcev

BACKGROUND: Multifunctional nanoparticles are known for their wide range of biomedical applications. Controlling the magnetic properties of these nanoparticles is imperative for various applications, including therapeutic angiogenesis. AIM: The study was performed to evaluate the magnetic properties and their control mechanisms by the external magnetic field. METHODS: A100 nm magnetic nanoparticle was placed in the magnetic field, and parametrically, the magnet field strength and distance were evaluated. Various models of magnetic strength and disposition were evaluated. Magnetic flux density, force/weight, and magnetic gradient strength were the parameters evaluated in the electromagnetic computational software. RESULTS: The seven-coil method with three centrally placed coils as Halbach array, and each coil with a flux density of 7 Tesla, and with a coil dimension of 20 cm × 20 cm (square model) of each coil showed a good magnetic strength and force/weight parameters in a distance of 15 cm from the centrally placed coil. The particles were then evaluated for their motion characteristics in saline. It showed good displacement and acceleration properties. After that, the particles were theoretically assessed in a similar mathematical model after parametrically correcting the drag force. After the application of high drag forces, the particles showed adequate motion characteristics. When the particle size was reduced further, the motion characteristics were preserved even with high drag forces. CONCLUSION: There is potential for a novel method of controlling multifunctional magnetic nanoparticles using high magnetic fields. Further studies are required to evaluate the motion characteristics of these particles in vivo and in vitro.


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