scholarly journals Six minute walk test in Italian children with cystic fibrosis aged 6 and 11

Author(s):  
Diletta Innocenti ◽  
Eleonora Masi ◽  
Giovanni Taccetti ◽  
Marco Genito ◽  
Elena Balestri ◽  
...  

Six Minute Walk Test (6MWT) is a field exercise test widely used in clinical practice, both in adults and in pediatric patients. The primary aim of the study is to evaluate the physical performance of the subjects and compare them with the predicted Italian values. The secondary aim is to verify the possible relationship between the 6MWT distance (6MWD) and the clinical variables of the sample. Italian children between 6-11 years affected by CF were recruited from 9 regional centres for CF. Short questionnaire assessments about their health state and physical activity routine was administered. Anthropometric characteristics were measured before the test and, peripheral oxygen saturation (SpO2), heart and respiratory rate were measured before and after a 6-minute walk test. The tests were performed according to the American Thoracic Society (ATS) guidelines. 6MWD was compared with the predicted distance calculated by the reference equation for healthy subjects of the same age.A total of 132 children were recruited (70 male) and completed the assessment. The mean (±SD) for 6MWD was 557.4(±69.9), male = 551.4(±80.0), female = 560.4(±63.3), however the predicted distance mean was 605m. A total of 101(76.5%) subjects practice regular physical activity. A total of 31(23%) had a FEV1 lower than their Lower Limits of Normal (LLN). Functional performance on the 6MWT was poorer among the CF patients than among the predicted distance estimated with Italian values. The correlation with the amount of physical activity and 6MWD has been verified.

2021 ◽  
Vol 28 (3) ◽  
pp. 267-275
Author(s):  
Mariana Kalazich-Rosales ◽  
Camila Mautner-Molina ◽  
Cecilia König-Araya ◽  
Francisca Fuentes-Leal ◽  
Carlos Cárcamo-Ibaceta ◽  
...  

ABSTRACT The six-minute walk test (6MWT) is widely used to measure functional capacity in special populations. However, the factors associated with its performance in candidates for bariatric surgery are unclear. Therefore, this study aimed to investigate the influence of anthropometric and physiological factors in the 6MWT performance in bariatric surgery candidates. This cross-sectional study included 107 candidates for bariatric surgery. Anthropometric factors considered: gender, weight, height, body mass index (BMI), waist-to-hip, and waist-to-height ratios. Along with distance covered during 6MWT, physiological factors such as ratings of perceived exertion (RPE) and heart rate reserve percentage used (%HRR) were recorded. Among the 107 patients (mean age: 39.6 years), 83 volunteers were accepted to perform the 6MWT. No gender differences were observed in terms of distance covered, %HRR, and RPE during the 6MWT. Moreover, BMI and %HRR explained 21% of the 6MWT distance covered. Furthermore, participants with BMI ≤41.5 kg/m2 walked ~50 meters more than their peers above this level (p=0.05). Interestingly, heart rate increase during the 6MWT was lower than described for healthy populations. BMI and %HRR partially explain the variability of the 6MWT performance in bariatric surgery candidates.


2018 ◽  
Vol 36 (4_suppl) ◽  
pp. 804-804
Author(s):  
Alejandro Alvarez-Bustos ◽  
Lourdes Gutierrez Gutierrez Sanz ◽  
Beatriz Nuñez García ◽  
Maria Soriano ◽  
Carmen Fiuza-Luces ◽  
...  

804 Background: Physical capability describes the ability to do the physical tasks of everyday living. Oncologists usually evaluate physical capability through anamnesis generating a performance status (PS) score. Some authors have proposed the use of cardiorespiratory reserve, muscular strength and objective evaluation of physical activity to avoid the subjective, unreliable and non-reproducible condition of PS. Methods: Patients with a recent diagnosis of colorectal cancer who accepted to participate were evaluated at the hospital setting. Walking speed was evaluated through both one-mile walk test and six-minute walk test. VO2max was calculated through the Kilne formula. Muscular strength was measured through dynamometry (hand-grip) and “sit to stand” test. Physical activity was objectively evaluated with accelerometers. Fatigue was evaluated through the PERFORM questionnaire (12-60). ECOG was evaluated by the medical oncologist. Results: 100 pats were recruited between March 15 and Jul 17. ECOG O/1/2 (80/14/2). 40 (40 %) were metastatic. Mean age 66 (25-81), Sex M/F; 68/32. Conclusions: Objective evaluation of physical condition is feasible at the hospital setting. There were no differences in BMI, heart rate, fatigue, muscular strength and objective functional performance (weekly PA) between localized and metastatic CRC. In metastatic pts with an excellent ECOG-PS the time to walk one mile and the estimated VO2max could be more sensitive than ECOG to evaluate the functional capacity impairment. In pts with cancer the One- mile walk test could be superior to the Six-minute walk to estimate the cardiorespiratory fitness. The objective evaluation of physical condition is a useful additional tool to select pts for aggressive therapies. [Table: see text]


Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Alexis L Beatty ◽  
Nelson B Schiller ◽  
Mary A Whooley

Background: The six-minute walk test (6MWT) is commonly used to assess functional exercise capacity in patients with heart or lung disease. However, its ability to predict events in patients with stable ischemic heart disease (IHD) is unknown. Methods: We measured 6MWT distance and treadmill exercise capacity in 556 outpatients with stable IHD between September 2000 and December 2002. Participants were followed for an average of 7.7 years to determine cardiovascular (CV) events (myocardial infarction, heart failure, or death). We used Cox proportional hazards models to evaluate 6MWT distance and treadmill exercise capacity as predictors of subsequent events. Results: Among the 556 patients, there were 82 heart failure hospitalizations, 63 myocardial infarctions, and 184 deaths from any cause. Patients in the lowest quartile of 6MWT distance (284-1375 ft) were 3 times as likely as patients in the highest quartile (1786-2746 ft) to experience CV events (62% vs. 22%, age-adjusted HR 3.15, 95%CI 1.98-5.03, p<0.0001). Each standard deviation (SD) decrease in 6MWT distance (342 ft) was associated with an 86% greater risk of heart failure (age-adjusted HR 1.86, 95%CI 1.51-2.31, p<0.0001), a 47% greater risk of myocardial infarction (age-adjusted HR 1.47, 95%CI 1.15-1.89, p=0.002), a 54% greater risk of death (age-adjusted HR 1.54, 95%CI 1.32-1.80, p<0.0001), and a 55% greater risk of any event (age-adjusted HR 1.55, 95%CI 1.35-1.78, p<0.0001). After adjustment for traditional risk factors and measures of cardiac disease severity (left ventricular ejection fraction, inducible ischemia, diastolic dysfunction, NT-proBNP and CRP), each SD decrease in 6MWT remained associated with a 38% greater risk of CV events (HR 1.38, 95%CI 1.10-1.74, p=0.005). 6MWT distance was similar to treadmill exercise capacity for predicting CV events (age-adjusted c-statistics 0.72 vs. 0.71, p=0.73 for comparison). Conclusions: Distance walked on 6MWT is as good as treadmill exercise capacity for predicting CV events in patients with stable IHD.


2009 ◽  
Vol 5 (5) ◽  
pp. 540-543 ◽  
Author(s):  
Shirley Aparecida Fabris de Souza ◽  
Joel Faintuch ◽  
Sonia Maria Fabris ◽  
Fernando Kenji Nampo ◽  
Cesar Luz ◽  
...  

Adaptation of the cardiovascular system to physical activity implies the development of functional or structural changes that should ensure the most efficient and economical use of energy during muscular contraction. The most studied data reactions in individuals engaged in various sports. The aim of our study was to study the functional changes of the heart, taking into account the functioning of the right and left ventricles of the heart and the adaptive capacity of the cardiovascular system in children with non-inflammatory diseases of the myocardium. Were examined 62 patients with non-inflammatory myocardial diseases, whose mean age was 14.56 ± 0.24 years. The control group consisted of 41 practically healthy peers. The functional state of the myocardium was assessed according to the results of the ultrasonic Doppler study of the heart in the “M” and “B” - modes, as well as in the mode of constant-wave and color scanning with a convex sensor using the standard method. To study tolerance to the minimum physical activity and its influence on the state of the cardiovascular system in children, a six-minute walk test was conducted. To assess the functional intensity of the cardiovascular system before and after the six-minute walk test, the following vegetative indices were calculated: an endurance coefficient according to the formula A. Quaasa and a double product. The vegetative Kerdo index and adaptation potential were calculated at rest. As a result of the study, it was found that in children with myocardial pathology, stress is observed in the adaptation mechanisms of the cardiovascular system, accompanied by a weakening of its functional capabilities and an increase in the work of the cardiac muscle at rest. This happens against the background of a decrease in the functioning of the left ventricle and an increase in the functioning of the right ventricle of the heart. These changes are accompanied by activation of the parasympathetic division of the autonomic nervous system in patients in all the studied groups, which indicates a more economical mode of functioning of the body systems.


2017 ◽  
Vol 20 (4) ◽  
pp. 4-12
Author(s):  
Chidozie E. Mbada ◽  
Temitope A. Osifeso ◽  
Olubusola E. Johnson ◽  
Adaobi M. Okonji ◽  
Emmanuel A. Odeyemi

The extent to which self-report activity measured by the International Physical Activity Questionnaire (IPAQ) can substitute performance-based functional capacity measured by the Six-Minute Walk Test (6MWT) remains inconclusive. This study assessed Physical Activity (PA) and Functional Exercise Capacity (FEC); and also determined the relationship between PA and FEC in apparently healthy young adults. A total of 342 (145 males and 197 females) undergraduates of Obafemi Awolowo University, Ile-Ile, Nigeria participated in the study. The IPAQ was used to assess PA, while FEC was assessed using the 6MWT, and expressed in terms of the Six-Minute Walk Distance (6MWD), Six-Minute Walk Work (6MWW), Maximum Oxygen Uptake (VO2max) and Metabolic Equivalent (METS). Anthropometric and cardiovascular parameters were measured following standardized procedures. Data was analyzed using descriptive and inferential statistics. The alpha level was set at 0.05. The mean age of the participants was 22.0±2.87 years. The mean IPAQ score of all participants was 1471.4±1086.93. The percentage for low, moderate and high PA was 19% (65), 41.2% (141) and 39.8% (136), respectively. The mean 6MWD, 6MWW, VO2max and METS were 639.47 ±66.6 m, 41805.0 ±8520.6 kg·m, 28.9 ±1.92 mlO2k-1min-1, 4.05 ±0.32 mL/kg, respectively. There were signifi cant positive correlations between PA and each of the 6MWD (r=0.268; p=0.001), 6MWW (r=0.219; p=0.001), VO2max (r=0.268; p=0.001), METS (r=0.268; p=0.001). Measures of exercise capacity were not signifi cantly correlated with the anthropometric variables (p>0.05). Self-report of physical activity in healthy young adults does not adequately substitute the results of the Six-Minute Walk Test. Mbada Ch.E., Osifeso T.A., Johnson O.E., Okonji A.M., Odeyemi E.A. Self-reported physical activity versus physical function capacity: alternatives for energy expenditure estimation. Med Rehabil 2016; 20(4): 4-12. DOI: 10.5604/01.3001.0009.5479 null


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