scholarly journals Devising a Pace-Based Definition for “The Wall”: An Observational Analysis of Marathoners' Subjective Experiences of Fatigue

2020 ◽  
Vol 55 (5) ◽  
pp. 494-500
Author(s):  
Cailbhe Doherty ◽  
Alison Keogh ◽  
Barry Smyth ◽  
Peter Megyesi ◽  
Brian Caulfield
Keyword(s):  
Standard Deviation ◽  
Receiver Operating Characteristic ◽  
Operating Characteristic ◽  
Outcome Measure ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Subjective Experiences ◽  
Cross Sectional ◽  
Subjective Reports ◽  
Receiver Operating

Context Many runners report “hitting The Wall” (HTW) during a marathon (42.2 km). However, the performance manifestation of this subjectively experienced phenomenon remains unclear. Objective To identify a pace-based classification for HTW by integrating subjective reports of fatigue and runners' pacing profiles during a marathon. Design Cross-sectional study. Setting Public race event (2018 Dublin Marathon). Patients or Other Participants Eighty-three runners (28 [34%] women, 55 [66%] men, age = 41.5 ± 9.1 years, height = 1.73 ± 0.09 m, mass = 70.2 ± 10.1 kg). Main Outcome Measure(s) The pacing profiles for respondents to our postrace questionnaire that concerned the phenomenon of HTW were evaluated. Receiver operating characteristic analyses were performed on discretized outcomes of the time series of marathoners' paces during the race. Results Using the receiver operating characteristic analyses, we observed that runners could be classified as having experienced HTW if they ran any 1-km segment 11% slower than the average of the remaining segments of the race (accuracy = 84.6%, sensitivity = 1, specificity = 0.6) or if the standard deviation of the normalized 1-km split times exceeded 0.0532 (accuracy = 83%, sensitivity = 0.818, specificity = 0.8). Similarly, runners could be classified as having experienced HTW if they ran any 5-km segment 7.3% slower than the average of the remaining 5-km segments of the race (accuracy = 84.6%, sensitivity = 1, specificity = 0.644) or if the standard deviation of the normalized 5-km split times exceeded 0.0346 (accuracy = 82%, sensitivity = 0.909, specificity = 0.622). Conclusions These pace-based criteria could be valuable to researchers evaluating HTW prevalence in cohorts for whom they lack subjective questionnaire data.

scholarly journals MicroRNAs-1299, -126-3p and -30e-3p as Potential Diagnostic Biomarkers for Prediabetes

Diagnostics ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 949
Author(s):  
Cecil J. Weale ◽  
Don M. Matshazi ◽  
Saarah F. G. Davids ◽  
Shanel Raghubeer ◽  
Rajiv T. Erasmus ◽  
...  
Keyword(s):  
Receiver Operating Characteristic ◽  
Operating Characteristic ◽  
Characteristic Curve ◽  
Predictive Ability ◽  
Roc Curves ◽  
Tolerance Test ◽  
Cross Sectional Study ◽  
Oral Glucose ◽  
Cross Sectional ◽  
Receiver Operating

This cross-sectional study investigated the association of miR-1299, -126-3p and -30e-3p with and their diagnostic capability for dysglycaemia in 1273 (men, n = 345) South Africans, aged >20 years. Glycaemic status was assessed by oral glucose tolerance test (OGTT). Whole blood microRNA (miRNA) expressions were assessed using TaqMan-based reverse transcription quantitative-PCR (RT-qPCR). Receiver operating characteristic (ROC) curves assessed the ability of each miRNA to discriminate dysglycaemia, while multivariable logistic regression analyses linked expression with dysglycaemia. In all, 207 (16.2%) and 94 (7.4%) participants had prediabetes and type 2 diabetes mellitus (T2DM), respectively. All three miRNAs were significantly highly expressed in individuals with prediabetes compared to normotolerant patients, p < 0.001. miR-30e-3p and miR-126-3p were also significantly more expressed in T2DM versus normotolerant patients, p < 0.001. In multivariable logistic regressions, the three miRNAs were consistently and continuously associated with prediabetes, while only miR-126-3p was associated with T2DM. The ROC analysis indicated all three miRNAs had a significant overall predictive ability to diagnose prediabetes, diabetes and the combination of both (dysglycaemia), with the area under the receiver operating characteristic curve (AUC) being significantly higher for miR-126-3p in prediabetes. For prediabetes diagnosis, miR-126-3p (AUC = 0.760) outperformed HbA1c (AUC = 0.695), p = 0.042. These results suggest that miR-1299, -126-3p and -30e-3p are associated with prediabetes, and measuring miR-126-3p could potentially contribute to diabetes risk screening strategies.

The Association Between Hands-On Instruction and Proper Child Safety Seat Installation

PEDIATRICS ◽  
2000 ◽  
Vol 106 (Supplement_3) ◽  
pp. 924-929
Author(s):  
Wendy G. Lane ◽  
Gilbert C. Liu ◽  
Elizabeth Newlin
Keyword(s):  
Primary Care ◽  
Outcome Measure ◽  
Private Insurance ◽  
Cross Sectional Study ◽  
Child Safety ◽  
Sectional Study ◽  
Cross Sectional ◽  
Main Outcome Measure ◽  
Hands On ◽  
Safety Seat

Objective. To determine if hands-on instruction in child safety seat (CSS) installation decreases the number of errors in installation. Design. Cross-sectional study. Setting. Primary care offices, emergency department, CSS checkpoint. Participants. Parents of children &lt;2 years old receiving medical care or attending a CSS check. Main Outcome Measure. Errors in CSS use. Results. Only 6.4% of parents had a correctly installed CSS. Hands-on instruction was associated with fewer errors in seat installation. Increased parent age, completion of college, and having private insurance were also associated with fewer errors in CSS placement. The majority of parents learned to install seats from reading the manual, from friends and relatives, and from figuring it out on their own. Conclusions. Errors in CSS installation are a significant problem. Hands-on instruction decreases the numbers of errors in CSS installation. However, few parents receive hands-on instruction from experts in CSS installation. Increases in correct CSS use could result from hands-on education by trained professionals.

scholarly journals Physical activity as an indicator of predictive functional disability in elderly

2012 ◽  
Vol 20 (2) ◽  
pp. 259-265 ◽  
Author(s):  
Jair Sindra Virtuoso Júnior ◽  
Sheilla Tribess ◽  
Thais Reis Silva De Paulo ◽  
Cristiane Alves Martins ◽  
Vicente Romo-Perez
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Operating Characteristic ◽  
Functional Disability ◽  
Cross Sectional Study ◽  
Physical Activities ◽  
Sectional Study ◽  
Cross Sectional ◽  
Important Indicator ◽  
Receiver Operating Characteristic Curves

To analyze the time spent on physical activity in female and male individuals as a predictor of the absence of functional disability in older adults, a cross-sectional study was conducted with 624 individuals. Receiver Operating Characteristic curves (ROC) were constructed and compared to areas of physical activity by gender and the absence of functional disability. We identified cutoffs of physical activity (minutes / week) to predict the absence of functional disability (CI 95%). It was found that there is a higher area under the ROC curve for the time spent on physical activities in females. It was observed that 280 minutes / week (women) or 410 minutes / week (men) were the best cutoff points for predicting the absence of functional disability. Time spent on physical activity practices can serve as an important indicator to sort priority groups for certain interventions.

scholarly journals Temperature Increases in the Human Achilles Tendon During Ultrasound Treatments With Commercial Ultrasound Gel and Full-Thickness and Half-Thickness Gel Pads

2010 ◽  
Vol 45 (4) ◽  
pp. 333-337 ◽  
Author(s):  
David O. Draper ◽  
Clinton G. Edvalson ◽  
Kenneth L. Knight ◽  
Dennis Eggett ◽  
Joseph Shurtz
Keyword(s):  
Achilles Tendon ◽  
Outcome Measure ◽  
Cross Sectional Study ◽  
Triceps Surae ◽  
Therapeutic Modality ◽  
Sectional Study ◽  
Cross Sectional ◽  
Main Outcome Measure ◽  
Internal Structures ◽  
Half Thickness

Abstract Context: Although originally manufactured for use in diagnostic imaging of internal structures, 2-cm-thick gel pads are also used as conducting media for therapeutic ultrasound over areas with bony prominences. Research on the ability of these pads to conduct enough energy to adequately heat tissues has provided mixed results. However, this research has mainly been performed on the triceps surae muscle, an area over which gel pads are not typically used. We wondered how much heating might be produced if a thinner pad was used over a tendon. Objective: To compare temperature rises in the human Achilles tendon during ultrasound treatments using ultrasound gel, a 2-cm-thick pad, and a 1-cm-thick pad. Design: Cross-sectional study. Setting: University therapeutic modality laboratory. Patients or Other Participants: Forty-eight healthy volunteers (24 women, 24 men). Intervention(s): We inserted a rigid thermocouple 1 cm deep into the Achilles tendon. Ultrasound was delivered at the following settings: 3 MHz, continuous, 1 W/cm2, 10 minutes. Main Outcome Measure(s): Temperature was recorded every 30 seconds for 10 minutes. Results: Temperature increased the most in the ultrasound gel group (increase  =  13.3°C, peak  =  42°C). The 1-cm-thick pad resulted in higher tendon temperature (increase  =  9.3°C, peak  =  37.8°C) than the 2-cm-thick pad (increase  =  6.5°C, peak  =  4.8°C). The 1-cm pad produced approximately 30% more heating than the 2-cm pad (SE  =  0.72, P &lt; .03). Conclusions: The thinner pad transmitted ultrasound more efficiently than the thicker pad. Thus, a gel pad of less than 1-cm thickness might be useful for superficial areas, such as the hands and ankles.

scholarly journals Who is at risk of occupational Q fever: new insights from a multi-profession cross-sectional study

BMJ Open ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. e030088 ◽  
Author(s):  
Tanja Groten ◽  
Karola Kuenzer ◽  
Udo Moog ◽  
Beate Hermann ◽  
Katrin Maier ◽  
...  
Keyword(s):  
At Risk ◽  
Primary Outcome ◽  
Outcome Measure ◽  
Q Fever ◽  
Cross Sectional Study ◽  
Primary Outcome Measure ◽  
Sectional Study ◽  
Cross Sectional ◽  
Seroprevalence Data ◽  
Regular Contact

ObjectivesQ fever is a zoonosis caused by the bacteriumCoxiella burnetii. It is recognised as an occupational hazard for individuals who are in regular contact with animal birth products. Data from the literature are not comparable because different serological assays perform very differently in detecting past infections. It is therefore essential to choose the right assay for obtaining reliable data of seroprevalence. Obstetricians are another profession potentially at risk of Q fever. They can be infected from birth products of women with Q fever during pregnancy. There is little data, however, for Q fever in this occupational group. Our study therefore had two purposes. The first was to obtain reliable seroprevalence data for occupational groups in regular contact with animal birth products by using an assay with proven excellent sensitivity and specificity for detecting past infections. The second purpose was to obtain primary data for obstetricians.DesignWe carried out a cross-sectional study.SettingThe study included shepherds, cattle farmers, veterinarians and obstetricians from Thuringia.Participants77 shepherds, 74 veterinarians, 14 cattle farmers, 17 office employees and 68 obstetricians participated. The control group consisted of 92 blood donors.Primary outcome measureThe primary outcome measure wasC. burnetiiphase II specific IgG. The assay used was evaluated for this purpose in a previous study.ResultsOf the 250 blood samples we analysed, the very highest seroprevalences (64%–77%) occurred in individuals with frequent animal contact. There were no significant differences between shepherds, cattle farmers and veterinarians. The seroprevalence in people working in administration was lower but still significantly greater than the control. No obstetricians or midwives tested positive.ConclusionsShepherds, cattle farmers and veterinarians have a high risk ofC. burnetiiinfection. However, our study clearly proves that there was no increased risk for people working in an obstetric department.

scholarly journals Closer to the Truth on National Fistula Prevalence After Unilateral Complete Cleft Lip and Palate Repair? The Cleft Care UK Study

2019 ◽  
Vol 57 (1) ◽  
pp. 5-13
Author(s):  
Arthur S. Yang ◽  
Bruce M. Richard ◽  
Andrew K. Wills ◽  
Osama Mahmoud ◽  
Jonathan R. Sandy ◽  
...  
Keyword(s):  
United Kingdom ◽  
Cleft Lip ◽  
Outcome Measure ◽  
Cleft Lip And Palate ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Palatal Fistula ◽  
The United Kingdom ◽  
Palate Repair

Objectives: To (1) determine the prevalence of nonperialveolar palatal fistula up to age 5 following repair of unilateral cleft lip and palate (UCLP) in the United Kingdom, (2) examine the association of palatoplasty techniques with fistula occurrence, and (3) describe the frequency of fistula repairs and their success. Design: Cross-sectional study. Setting: All 11 centralized regional cleft centers in the United Kingdom. Participants: Two hundred sixty-eight children born between 2005 and 2007 recruited by Cleft Care UK, a nationwide cross-sectional study of all 5-year-old children born with nonsyndromic UCLP. Main Outcome Measure: Nonperialveolar palatal fistula prevalence up to age 5. Results: Fistulas were found in 72 children (31.3%, 95% confidence interval: 25.4%-37.7%) and had no significant association with palate repair sequences. Twenty-four fistulas were repaired by age 5, 12 of which had data showing 10 (83.3%) successful repairs. Conclusion: The prevalence of nonperialveolar fistulas following primary palatoplasty of UCLP in the United Kingdom was higher than previously reported. This information should be part of the preoperative discussion with families. Prospective collection of the presence of fistulas will be necessary before we can associate the occurrence of fistulas with a surgeon, institution, surgical technique, or protocol of care.

scholarly journals A cross-sectional study of relationship between self-esteem and self-concept of students of medical sciences

2018 ◽  
Vol 6 (3) ◽  
pp. 747
Author(s):  
Mehdi Amirkhani ◽  
Fatemeh Habibi ◽  
Azadeh Hakimi ◽  
Majid Najafi Kalyani ◽  
Javad Salami
Keyword(s):  
Standard Deviation ◽  
Self Esteem ◽  
Cross Sectional Study ◽  
Male Students ◽  
Self Concept ◽  
Sectional Study ◽  
Medical Sciences ◽  
Cross Sectional ◽  
Significant Difference ◽  
The Mean

Background: Identification of the role of factors such as self-esteem and self-efficacy and the investigation of their relationship among students can bring about improvement of educational planning and enhance the teaching outcome. This study aimed at investigating the relationship between self-esteem and self-efficacy among the students of medical sciences.Methods: The present study is an analytical-descriptive which was conducted as a cross-sectional study on 394 students of Fasa University of Medical Sciences in 2016. In order to collect the data two questionnaires were used namely, Coopersmith Self-Esteem Inventory (CSEI) and Rogers Self-concept Questionnaire. The data were analyzed using SPSS 22. The researchers used descriptive and inferential statistics such as t-test, chi-square one-way ANOVA, and correlation to analyze the data.Results: The mean and the standard deviation of self-esteem scores of female and male students were 38.23±6.80 and 37.51±6.67 respectively. The mean and the standard deviation of self-concept scores of female and male students were 9.49±3.53 and 9.43±4.14 respectively. The mean of self-concept scores of students of different majors had statistically significant difference with each other (0.011), whereas there was no statistically significant difference in self-esteem scores among students with different majors (0.442).Conclusions: Considering the statistically significant difference in students’ self-concept scores in different majors, it is suggested that we take right approaches to the improvement and enhancement of individuals’ self-concept and the creation of positive feedback.

scholarly journals Penilaian kualitas kortikal mandibula pasien diabetes mellitus tipe 2 dengan analisis radiomorfometrik pada radiograf panoramik

2020 ◽  
Vol 4 (1) ◽  
pp. 23
Author(s):  
Annisa Putri ◽  
Aga Satria Nurrachman ◽  
Lusi Epsilawati ◽  
Azhari Azhari
Keyword(s):  
Diabetes Mellitus ◽  
Standard Deviation ◽  
Radiological Finding ◽  
Secondary Data ◽  
Cross Sectional Study ◽  
Normal Sample ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mandibular Cortical Index

Objectives: This research aims to evaluate radiological finding on bone of patients with T2DM (type 2 Diabetes Mellitus) by evaluating mandibular cortical quality using radiomorphometric assessment  specifically  MCI (Mandibular Cortical Index) and AI (Antegonial Index). Material and Methods: This research is a descriptive analytic cross-sectional study, populations and samples using secondary data radiographs of T2DM patients that have been proven by medical statement from a doctor and normal sample were selected according to specified criterias. Results: It showed between group  consisting of patients with T2DM and another one with normal patients, both have dominant result of MCI assessment type C2. While the result of Antegonial Index assessment there were a difference of cortical thickness between two groups. The average AI value from normal patients were 4,179 with standard deviation of 0.420, while another group with T2DM were 3,641 with standard deviation of 0.477. Conclusion: Based on the results of the study, it was found that there has been a significance difference of cortical bone qualities between two groups of samples which can be seen from the result of Antegonial Index, a T2DM patients has average values lower than normal patients, while for the results of MCI assessment between two groups have similar types.  

scholarly journals A Comparative Study of the Sarcopenia Screening in Older Patients with Interstitial Lung Disease

2021 ◽  
Author(s):  
Masatoshi Hanada ◽  
Noriho Sakamoto ◽  
Hiroshi Ishimoto ◽  
Takashi Kido ◽  
Takuto Miyamura ◽  
...  
Keyword(s):  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Operating Characteristic ◽  
Cross Sectional Study ◽  
Screening Tools ◽  
Calf Circumference ◽  
Sectional Study ◽  
Cross Sectional ◽  
Receiver Operating Characteristic Curves ◽  
Climbing Stairs

Abstract Background: The calf circumference (CalF), the strength, assistance in walking, rising from a chair, climbing stairs, and falls (SARC-F) and the SARC-CalF questionnaires for sarcopenia screening have been used by Asian Working Group for Sarcopenia 2019 (AWGS 2019). The aim of this study was to assess accuracy of these three sarcopenia screening tools in patients with interstitial lung disease. Methods: In this cross-sectional study, stable patients with interstitial lung disease were enrolled. The SARC-F, SARC-CalF, and CalF, used in patients with interstitial lung disease, were compared to the diagnostic criteria proposed by AWGS 2019. The accuracy of screening tools was compared using sensitivity and specificity. Moreover, areas under the receiver operating characteristic curves (AUC) were computed. Results: Seventy eight patients were analyzed, and sarcopenia was identified in 25 (32.1%) patients with interstitial lung disease by the AWGS 2019 criteria. The sensitivity of the CalF was highest (96%) of the three screening tools, while the specificity was 60%. The sensitivity of SARC-F and SARC-CalF were 24% and 68%, while the specificity were 92% and 66%, respectively. The AUCs of CalF, SARC-F, and SARC-CalF in all patients were 0.78, 0.58, and 0.67, respectively. Conclusions: The CalF is most suitable for screening sarcopenia in patients with interstitial lung disease, while SARC-F and SARC-CalF are not.

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