scholarly journals Exercise Intolerance in Individuals With Postconcussion Syndrome

2013 ◽  
Vol 48 (5) ◽  
pp. 627-635 ◽  
Author(s):  
Karl F. Kozlowski ◽  
James Graham ◽  
John J. Leddy ◽  
Lee Devinney-Boymel ◽  
Barry S. Willer

Context: Little is known about exercise intolerance or the utility of an exercise evaluation in patients with postconcussion syndrome (PCS). Objective: To assess exercise intolerance in male and female patients with PCS. Design: Cross-sectional study. Setting: Laboratory setting. Patients or Other Participants: Participants included a convenience sample of 34 patients with PCS (17 males, 17 females; age = 25.9 ± 10.9 years) and 22 uninjured individuals on whom we gathered historical deidentified laboratory data (control group; 11 males, 11 females; age = 23.3 ± 6.2 years). Main Outcome Measure(s): Self-reported symptoms, heart rate, systolic and diastolic blood pressures (BPs), and the Borg rating of perceived exertion were measured before, during each minute of, and immediately after a graded treadmill exercise test (Balke protocol). Exercise was stopped when participants could no longer maintain the effort or reported the onset of or increase in PCS symptoms. Results: Exercise test duration (8.5 ± 4.4 minutes versus 17.9 ± 3.6 minutes; t51 = 1.8, P < .001), heart rate (142.8 ± 24.1 versus 175.2 ± 17.4; t54 = −5.5, P < .001), and systolic BP (142.1 ± 18.3 mm Hg versus 155.5 ± 24.5 mm Hg; t53 = 2.3, P = .02) were lower, and diastolic BP (78.4 ± 10.2 mm Hg versus 73.5 ± 11.7 mm Hg; t53 = 2.2, P = .03) was higher at test cessation in the PCS than control group. Cox regression showed the odds of a shorter exercise duration were nearly 8 times greater in the PCS than control group (hazard ratio = 7.93; 95% confidence interval = 3.39, 18.56). In the general linear models that adjusted for differences in test duration, rating of perceived exertion was the only physiologic measure to show an overall difference between groups, with the control group reporting higher ratings than the PCS group (t53 = −6.0, P < .001). Within the PCS group, systolic BP was the only measure to show a sex effect, with males showing higher pressure readings than females throughout the exercise tests (t31 = 2.8, P = .009). Conclusions: Patients with PCS had a symptom-limited response to exercise, and the treadmill test was a potentially useful tool to monitor the recovery from PCS.

1996 ◽  
Vol 8 (3) ◽  
pp. 251-258 ◽  
Author(s):  
Glen E. Duncan ◽  
Anthony D. Mahon ◽  
Julie A. Gay ◽  
Jennifer J. Sherwood

Physiological and perceptual responses at ventilatory threshold (VT) and V̇O2 peak were examined in 10 male children (10.2 ± 1.3 yrs) during graded treadmill and cycle exercise. Treadmill V̇O2peak (57.9 ± 6.7 ml · kg−1 · min−1) was higher (p < .05) than the cycle (51.7 ± 7.7 ml · kg−1 · min−1). Ventilation and heart rate (HR) were higher (p < .05) on the treadmill, while respiratory exchange ratio (RER), rating of perceived exertion (RPE), capillary blood lactate, and test duration were similar between tests. The V̇O2 at VT was higher (p < .05) on the treadmill (36.7 ± 4.6 ml · kg−1 · min−1) than the cycle (32.5 ± 4.4 ml · kg−1 · min−1). When VT was expressed as a percentage of V̇O2 peak, there was no difference (p > .05) between tests. The RPE at VT, HR at VT, and VT expressed as a percentage of HRpeak were also similar (p > .05) between tests. Similar to V̇O2 peak, the V̇O2 at VT is dependent on the mode of exercise. However, when VT is expressed as a percentage of V̇O2 peak, it is independent of testing modality. The RPE at VT appears to be linked to a percentage of V̇O2 peak rather than an absolute V̇O2.


2021 ◽  
Author(s):  
Gaurav Gupta ◽  
Emilie Paquet-Proulx ◽  
Markus Besemann ◽  
Kira Burton ◽  
Sasha Lalonde ◽  
...  

Introduction - An Ideal battery of testing for function would be inexpensive, easily administered, standardized and validated for multiple health issues. This would also be sensitive to change over time and able to extrapolate avocational and vocational tasks. The data collection exercise for this study included both subjective and objective measures which include the Short Form Health Survey 12 (SF-12), the 2 minute walk test (2MWT) and a newly developed upper extremity strength/conditioning activity called the Elevation and Movement Lift test (EMLi). Methods - A convenience sample of 102 patients with chronic pain. They were seen in the Canadian Forces Health Services Unit (CFHSU (O)) Physiatry Clinic between January-September 2019 and were asked to complete the data intake protocol. This included: completing a questionnaire with the Numeric Rating Pain Scale (NRS) covering the previous 7 days, the SF-12, and completed the 2 MWT and EMLi. Results - For the 2MWT heart rate, perceived exertion and number of steps were all increased for patients with chronic pain compared to the control group. There was no difference noted between patients with upper/lower body pain. In patients with chronic pain SF-12 physical function score negatively correlated with perceived exertion but not performance. As for the EMLI test, all groups had similar perceived exertion and heart rate outcomes but a reduced performance was noted with the upper extremity group. Discussion - For the 2MWT, the individuals performance related to effort and not their pain state, PE and SF-12. This suggests a higher capacity for walking then the patients realise. As for the EMLi, individuals performance was poorer for same level of effort. This correlates to their perceived function as seen on the SF-12 which might measure pain related dysfunction. Conclusion -The 2MWT performance was effort dependent and not correlated with perceived abilities. Therefore it can be used to challenge patient performance. EMLi performance correlated with perception and upper extremity pain. This could be used to set clinical training targets and monitor each individuals progress.


2012 ◽  
Vol 29 (2) ◽  
pp. 151-160 ◽  
Author(s):  
Anthony D. Mahon ◽  
Megan E. Woodruff ◽  
Mary P. Horn ◽  
Andrea D. Marjerrison ◽  
Andrew S. Cole

The effect of stimulant medication use by children with attention deficit/hyper-activity disorder (ADHD) on the rating of perceived exertion (RPE)—heart rate (HR) relationship was examined. Children with ADHD (n = 20; 11.3 ± 1.8 yrs) and children without ADHD (n = 25; 11.2 ± 2.1 yrs) were studied. Children with ADHD were examined while on their usual dose of medication on the day of study. HR and RPE, using the OMNI RPE scale, were assessed during a graded exercise to peak voluntary effort. The RPE-HR relationship was determined individually and the intercept and slope responses were compared between groups. The intercept was 132.4 ± 19.5 bpm for children with ADHD and 120.6 ± 15.7 bpm for children without ADHD. The slope was 7.3 ± 1.9 bpm/RPE for the children with ADHD and 8.1 ± 1.6 bpm/RPE for the children without ADHD. For the group with ADHD the intercept and slope values fell outside of the 95% CI observed in the control group. The altered relationship between RPE and HR with stimulant medication use in children with ADHD has practical implications with respect to the use of HR and RPE to monitor exercise intensity.


2008 ◽  
Vol 33 (1) ◽  
pp. 61-67 ◽  
Author(s):  
Barry Braun ◽  
Pamela Eze ◽  
Brooke R. Stephens ◽  
Todd A. Hagobian ◽  
Carrie G. Sharoff ◽  
...  

Individually, exercise and the drug metformin have been shown to prevent or delay type 2 diabetes. Metformin mildly inhibits complex I of the electron transport system and may impact aerobic capacity in people exercising while taking metformin. The purpose of the study was to evaluate the effects of metformin on maximal aerobic capacity in healthy individuals without mitochondrial dysfunction. Seventeen healthy, normal-weight men (n = 11) and women (n = 6) participated in a double-blind, placebo-controlled, cross-over design. Peak aerobic capacity was measured twice using a continuous, incrementally graded protocol; once after 7–9 d of metformin (final dose = 2000 mg/d) and once with placebo, with 1 week between tests. The order of the conditions was counterbalanced. Peak oxygen uptake (VO2 peak), heart rate (HR), ventilation (VE), respiratory exchange ratio (RER), rating of perceived exertion (RPE), and test duration were compared across conditions using paired t tests with the R statistical program. VO2 peak (–2.7%), peak heart rate (–2.0%), peak ventilation (–6.2%), peak RER (–3.0%), and exercise duration (–4.1%) were all reduced slightly, but significantly, with metformin (all p < 0.05). There was no effect of metformin on RPE or ventilatory breakpoint. Correlations between the decrement in VO2 peak and any of the other outcome variables were weak (r2 < 0.20) and not significant. Short-term treatment with metformin has statistically significant, but physiologically subtle, effects that reduce key outcomes related to maximal exercise capacity. Whether this small but consistent effect is manifested in people with insulin resistance or diabetes who already have some degree of mitochondrial dysfunction remains to be determined.


2021 ◽  
Vol 12 ◽  
Author(s):  
Tino Stöckel ◽  
Robert Grimm

School physical education (PE) has the potential to contribute to public-health promotion and well-being, but oftentimes students' lack of motivation toward PE or physical activity in general, especially during adolescence, diminishes, or eradicates the positive effects associated with PE. Therefore, practical approaches are required that help teachers to increase or awake students intrinsic motivation toward PE, for which self-determination theory may provide the conceptual framework. In that regard, the purpose of the present study was to examine whether the use of real-time, heart rate feedback (as a method to support students' need for autonomy and competence) during regular PE lessons has the potential to increase students' autonomous motivation and physical effort. To achieve this, we had forty healthy adolescents between 16 and 17 years of age run for 30 min either with (experimental group, EG) or without (control group, CG) real-time, individualized heart rate feedback during a regular PE class and compared physical and perceived exertion as well as joy of running between the two groups. Participants were randomly assigned to the groups. Our data revealed that participants in the EG enjoyed running more than participants in the CG (joy of running was 3.20 in the EG vs. 2.63 in the CG, p = 0.03) despite a higher physical (163 to 178 in EG vs. 141 to 156 beats per minute in the CG, p &lt; 0.001) and perceived exertion (rating of perceived exertion of 13.22 in the EG vs. 10.59 in the CG, p = 0.02). That means, running with real-time, individualized heart rate feedback apparently increased participants' motivation to run and to enjoy running at higher levels of exertion. In that regard, real-time, individualized activity feedback should be implemented in regular PE classes systematically and repeatedly to create a controllable and attainable situation that allows students to actively adjust their own behavior to achieve appealing and realistic goals.


Author(s):  
Claudio Perret ◽  
Kathrin Hartmann

AbstractThe heart rate-based lactate minimum test is a highly reproducible exercise test. However, the relation between lactate minimum determined by this test and maximal lactate steady state in running and cycling is still unclear. Twelve endurance-trained men performed this test in running and cycling. Exercise intensity at maximal lactate steady state was determined by performing several constant heart rate endurance tests for both exercise modes. Heart rate, power output, lactate concentration, oxygen uptake and rating of perceived exertion at lactate minimum, maximal lactate steady state and maximal performance were analysed. All parameters were significantly higher at maximal lactate steady state compared to lactate minimum for running and cycling. Significant correlations (p<0.05) between maximal lactate steady state and lactate minimum data were found. Peak heart rate and peak oxygen uptake were significantly higher for running versus cycling. Nevertheless, the exercise mode had no influence on relative (in percentage of maximal values) heart rate at lactate minimum (p=0.099) in contrast to relative power output (p=0.002). In conclusion, all measured parameters at lactate minimum were significantly lower but highly correlated with values at maximal lactate steady state in running and cycling, which allows to roughly estimate exercise intensity at maximal lactate steady state with one single exercise test.


Author(s):  
Alice Iannaccone ◽  
Daniele Conte ◽  
Cristina Cortis ◽  
Andrea Fusco

Internal load can be objectively measured by heart rate-based models, such as Edwards’ summated heart rate zones, or subjectively by session rating of perceived exertion. The relationship between internal loads assessed via heart rate-based models and session rating of perceived exertion is usually studied through simple correlations, although the Linear Mixed Model could represent a more appropriate statistical procedure to deal with intrasubject variability. This study aimed to compare conventional correlations and the Linear Mixed Model to assess the relationships between objective and subjective measures of internal load in team sports. Thirteen male youth beach handball players (15.9 ± 0.3 years) were monitored (14 training sessions; 7 official matches). Correlation coefficients were used to correlate the objective and subjective internal load. The Linear Mixed Model was used to model the relationship between objective and subjective measures of internal load data by considering each player individual response as random effect. Random intercepts were used and then random slopes were added. The likelihood-ratio test was used to compare statistical models. The correlation coefficient for the overall relationship between the objective and subjective internal data was very large (r = 0.74; ρ = 0.78). The Linear Mixed Model using both random slopes and random intercepts better explained (p < 0.001) the relationship between internal load measures. Researchers are encouraged to apply the Linear Mixed Models rather than correlation to analyze internal load relationships in team sports since it allows for the consideration of the individuality of players.


2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Kelvin Euton Oliveira Carmo ◽  
Diego Ignácio Valenzuela Pérez ◽  
Charles Nardelli Valido ◽  
Jymmys Lopes dos Santos ◽  
Bianca Miarka ◽  
...  

Abstract Background Nutritional ergogenic aids are foods or nutrients that can improve physical performance. Among these foods with ergogenic properties, caffeine has shown that it can increase the fat catabolism, strength, and improve the cognition and time reaction of an athlete, therefore, it is hoped that it can improve the performance of judokas. This study through a double-blind crossover (supplement X placebo) protocol, investigated the effects caffeine supplementation (single capsule containing 5 mg/kg body mass intake 60 min before the session) on biochemical, anthropometrical, physical, subjective and hemodynamic variables measured before, during and after two typical judo trainingcxs sessions (120-min: 40-min of gymnastics; 40-min of specific technics and; 40-min of judo combat). Methods 8 high-level athletes (21.4 ± 2.0 years; 83.6 ± 15.2 kg; 1.8 ± 0.1 m; 17.9 ± 7.0 Fat%) were evaluated before and after each training for body mass, hydration, upper and lower limb power, performance in the special judo fitness test (SJFT), free fatty acids (FFA) in plasma, uric acid, glucose, lactate, heart rate, and pain. In addition, heart rate, FFA in plasma, uric acid, glucose, lactate, rating of perceived exertion and pain were assessed during the training. Results At 120 min, supplementation resulted in a higher concentration of plasma FFA (1.5 ± 0.5 vs. 1.0 ± 0.3 mmol/L; p = 0.047) and lactate (4.9 ± 1.8 vs. 3.0 ± 1.2 mmol/L; p = 0.047), and a lower concentration of uric acid (5.4 ± 0.9 vs. 7.0 ± 1.5 mg/dL; p = 0.04). Supplementation also resulted in performance maintenance (fatigue index) in the SJFT (Δ0.3 ± 2.0 vs Δ1.7 ± 2.5, for caffeine and placebo respectively, p = 0.046). No adverse effects were observed. Conclusion Based on the applied dose, intake time, and sample of this study, we can conclude that caffeine produces an ergogenic biochemical effect, and improves performance in judo athletes.


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