scholarly journals Quantitative analysis of serum levels of trace elements in patients with oral submucous fibrosis and oral squamous cell carcinoma: A randomized cross-sectional study

2014 ◽  
Vol 18 (1) ◽  
pp. 46 ◽  
Author(s):  
P Sharada ◽  
M Jyotsna ◽  
S Chitra ◽  
SreelathaS Hosthor ◽  
Pushpalatha Mahesh ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Trace Elements ◽  
Quantitative Analysis ◽  
Oral Squamous Cell Carcinoma ◽  
Oral Submucous Fibrosis ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Submucous Fibrosis

scholarly journals Frequency and Determinants of Tongue Lesions among Patients Reported in a Teaching Institute: A Cross-Sectional Study

2021 ◽  
pp. 59-68
Author(s):  
Mehwish Feroz Ali ◽  
Gulrukh Askary ◽  
Shahrukh Saran ◽  
Adnan Zaidi ◽  
Farwa Sajjad ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Study Design ◽  
Squamous Cell ◽  
Oral Submucous Fibrosis ◽  
Cross Sectional Study ◽  
Oral Lesions ◽  
Sectional Study ◽  
Cross Sectional

Aims: The purpose of the study is to evaluate the frequency, distribution and determinants of tongue lesions in our teaching institute. Also to find an association of common tongue lesions with various study variables. Study Design: Cross-sectional study design. Place and Duration of Study: The study was conducted at Fatima Jinnah Dental College & Hospital, Karachi, Pakistan. All the lesions presented on the tongue were included reported from January 2017 to December 2020. Methodology: There were 670 oral lesions documented in the Department of Oral Pathology and Oral Medicine out of which 93 (13.8%) represented tongue lesions. We included 93 patients with tongue lesions (45 men, 48 women; age range 18-80 years). These lesions include the atrophic tongue, geographic tongue, candidiasis, keratotic lesion, ulceration, oral pigmentation, fibroma, black hairy tongue, traumatic neuroma, herpes infection, oral submucous fibrosis, and oral squamous cell carcinoma. Results: In the study, common clinical presentations on the tongue were ulceration (29%), erythematous/depapillated tongue (22.6%), white keratotic and plaque-like lesions (21.6%), and black discoloration (8.6%). The clinical presentation was statistically associated with gender (p=0.03), age (p=0.04) and site of lesion (p<.001). Atrophic glossitis (19.4%), traumatic ulcer (12.9%), pseudomembranous candidiasis (12.9%), oral pigmentation (8.6%), oral squamous cell carcinoma (7.5%), geographic tongue (6.5%), recurrent aphthous stomatitis (6.5%), and frictional keratosis (6.5%) were most commonly reported tongue lesions. There was a relationship of tongue lesions with causes and site of the lesion (P<0.001). Conclusion: Initial tongue lesions may reflect underlying massive abnormal changes and this could be an early diagnostic parameter.  Through vigilant screening of the oral mucosa, we may be able to detect such mucosal alterations and search out the possible cause in order to provide effective treatment to the patient. In this way, we may also prevent the malignant transformation of any susceptible oral lesions.

scholarly journals Gambaran Kebiasaan Menyirih dan Lesi Mukosa Mulut pada Mahasiswa Papua Di Manado

e-GIGI ◽  
2013 ◽  
Vol 1 (2) ◽  
Author(s):  
Dame R. Marbun
Keyword(s):  
Oral Submucous Fibrosis ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Driving Factor ◽  
Sectional Study ◽  
Cross Sectional ◽  
Slaked Lime ◽  
Oral Mucosal Lesions ◽  
Submucous Fibrosis ◽  
Mucosal Lesions

Kebiasaan menyirih telah dilakukan sejak dahulu kala di Indonesia, khususnya pada suku Papua. Banyak anggapan masyarakat bahwa menyirih dapat menguatkan gigi geligi dan menghambat terjadinya karies, namun dibalik dampak positif dari menyirih ini, ada juga dampak negatifnya berupa timbulnya lesi pada mukosa yang melapisi rongga mulut.Tujuan penelitian ini yaitu untuk memperoleh gambaran kebiasaan menyirih pada mahasiswa Papua di Kota Manado, mencakup: tujuan menyirih, bahan campuran menyirih, lamanya kebiasaan menyirih, frekuensi menyirih, dan faktor pendorong kebiasaan menyirih serta untuk mengetahui gambaran lesi mukosa mulut pada mahasiswa Papua di Kota Manado.Jenis penelitian ini yaitu penelitian desktiptif dengan pendekatan cross-sectional study. Teknik pengambilan sampel yang digunakan ialah total sampling dengan jumlah sampel 30 orang. Dari 30 subjek yang diperiksa, sebagian besar merupakan wanita, usia 17-27 tahun. Lamanya menyirih terbanyak 6-10 tahun, dengan frekuensi terbanyak 1-3 kali sehari, bahan campuran menyirih yang paling banyak digunakan ialah campuran sirih, pinang dan kapur. Faktor pendorong utama menyirih yakni karena keinginan sendiri, dimana tujuan menyirih terbanyak yakni agar gigi menjadi kuat dan sehat. Dari 30 subjek ada 29 orang (96,66%) memiliki lesi dalam rongga mulutnya. Lesi yang diduga sebagai Oral Submucous Fibrosis yakni sebanyak 90% dan lesi yang diduga sebagai Betel Chewers Mucosa sebanyak 6,66%.Kata kunci: Kebiasaan menyirih, lesi mukosa mulut, Oral Submucous Fibrosis, Betel Chewer’s MucosaABSTRACTBetel chewing as a habit has been done since a long time ago in Indonesia, especially in Papua. There are some public perceptions that betel chewing can strengthen teeth and prevent caries. But, behind the positive effect of betel chewing, there are negative effects too, such as the onset of lesions in the oral mucosa.The purpose of this research is to get an overview of betel chewing habit on Papuan students in Manado, including the purpose of betel chewing, the complete material of betel chewing, duration of betel chewing, frequency of betel chewing, the driving factor of betel chewing, and to get an overview on oral mucosal lesions on Papuan students in Manado.The type of this research is descriptive research with a cross - sectional study. The sampling technique is total sampling with a sample size of 30 people. The 30 examined subjects, mostly women with age ranging from 17-27 years. The most length of chewing from 6-10 years, with the highest frequency of chewing 1-3 times a day, the average mixture of betel commonly used is betel, areca nut and slaked lime. The major driving factor in betel chewing is their own desire and the most common purpose is to get a strong and healthy teeth. 29 of 30 subjects (96,66%) have lesions in the oral cavity. In 90% of the sample, expected as Oral Submucous Fibrosis and in 6,66% expected as Betel Chewer’s Mucosa.Keyword: Betel chewing habit, oral mucosal lesions, Oral Submucous Fibrosis, Betel Chewer’s Mucosa

scholarly journals Habit-associated salivary pH changes in oral submucous fibrosis-A controlled cross-sectional study

2015 ◽  
Vol 19 (2) ◽  
pp. 175 ◽  
Author(s):  
Mandana Donoghue ◽  
PraveenS Basandi ◽  
H Adarsh ◽  
GS Madhushankari ◽  
M Selvamani ◽  
...  
Keyword(s):  
Oral Submucous Fibrosis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Ph Changes ◽  
Salivary Ph ◽  
Submucous Fibrosis

Simultaneous occurrence of Epstein-Barr virus (EBV) in periodontal pockets and in oral squamous cell carcinoma: a cross-sectional study

2021 ◽  
Author(s):  
Humberto Jácome-Santos ◽  
Naira da Silva e Silva ◽  
Renata Gonçalves Resende ◽  
Helder Henrique Costa Pinheiro ◽  
Luiz Fernando Almeida Machado ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Epstein Barr Virus ◽  
Cross Sectional Study ◽  
Simultaneous Occurrence ◽  
Sectional Study ◽  
Cross Sectional ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Serum levels of matrix metalloproteinase-2 in patients with oral submucous fibrosis and oral squamous cell carcinoma

2020 ◽  
Vol 8 (2) ◽  
pp. 636
Author(s):  
Pooja Kherde ◽  
Suchitra Gosavi
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Matrix Metalloproteinase ◽  
Healthy Subjects ◽  
Oral Submucous Fibrosis ◽  
Positive Association ◽  
Serum Levels ◽  
Matrix Metalloproteinase 2 ◽  
Submucous Fibrosis ◽  
The Mean

Background: Matrix metalloproteinase-2 (MMP-2), which is supposed to enable cancer cells cross the basement membrane and metastasize by selectively cleaving type IV collagen, is anticipated to be a good diagnostic and prognostic marker in oral squamous cell carcinoma (OSCC) and oral submucous fibrosis (OSMF). Thus, the study is aimed to estimate and compare the serum MMP-2 levels in patients with OSMF and OSCC.Methods: The study was conducted on 88 subjects, divided into three groups; Group I (healthy subjects, n=28), Group II (patients with OSMF, n=30), and Group III (patients with OSCC, n=30). Serum levels of MMP-2 were estimated and compared among the groups and further with the clinical parameters within the groups.Results: The mean serum MMP-2 levels in patients with OSMF (2.87±1.04 ng/mL) and with OSCC (11.55±2.16 ng/mL) were significantly higher than the healthy subjects (0.93±0.26 ng/mL) (p <0.0001, for both). Furthermore, the mean serum MMP-2 levels in OSMF subjects had a positive association with inter-incisal opening (IIO), however, there was no association with the degree of burning sensation. Likewise, in subjects with OSCC, levels of serum MMP-2 showed positive association with histopathological grades, however, significant association with the site of occurrence and primary tumor size was not found.Conclusions: Elevated serum MMP-2 levels can be used as a screening tool in the early detection of OSMF and OSCC cases. Moreover, MMP-2 might be a good marker in evaluating the tumor grade in OSCC and the IIO in OSMF.

Sign in / Sign up

Export Citation Format

Share Document