scholarly journals Antihypertensive activity of combination of anredera cordifolia (Ten.) V. Steenis and Sonchus arvensis L. leaves on Epinephrine Induced male Wistar Rat

2021 ◽  
Vol 12 (4) ◽  
pp. 384
Author(s):  
ElinYulinah Sukandar ◽  
Nova Suliska ◽  
Suryani ◽  
Muhamad Insanu
Keyword(s):  
Wistar Rat ◽  
Antihypertensive Activity ◽  
Sonchus Arvensis

scholarly journals Antihypertensive activity of ethanol extract combination of Anredera cordifolia (Ten.) v. Steenis and Sonchus arvensis L. leaves on angiotensin II- induced male wistar rat

2019 ◽  
Vol 23 (6) ◽  
pp. 1090-1097
Author(s):  
Elin Yulinah SUKANDAR ◽  
Afrillia Nuryanti GARMANA ◽  
Anggi Utri AIDASARI ◽  
Audrey Amira CRYSTALIA
Keyword(s):  
Angiotensin Ii ◽  
Ethanol Extract ◽  
Wistar Rat ◽  
Antihypertensive Activity ◽  
Sonchus Arvensis

scholarly journals Cardioprotective Potential of Ethanol Extract of Sonchus Arvensis L. Leaves on Isoproterenol-Induced Myocardial Infarction in Rat

2018 ◽  
Vol 16 (1) ◽  
pp. 20
Author(s):  
Neng Fisheri Kurniati ◽  
Elin Yulinah Sukandar ◽  
Rian Pardilah ◽  
Nova Suliska ◽  
Dhyan Kusuma Ayuningtyas
Keyword(s):  
Myocardial Infarction ◽  
Creatine Kinase ◽  
Ethanol Extract ◽  
Wistar Rat ◽  
Positive Control ◽  
Negative Control ◽  
Albino Rats ◽  
Creatine Kinase Mb ◽  
Wistar Albino Rats ◽  
Sonchus Arvensis

Sonchus arvensis L. leaves have been used traditionally to treat various disease conditions. This study is designed to evaluate cardioprotective potential of ethanol extract of S. arvensis leaves on isoproterenol-induced myocardial infarction in Wistar rat. Male Wistar albino rats were divided into three main groups: negative control (saline only), positive control (isoproterenol only), and S. arvensis extract treated groups. S. arvensis extract was administered in three doses; 50, 100, and 200 mg/kg b.w. p.o for 14 days. On day 13 and 14, isoproterenol (85 mg/kg bw) was given intraperitoneally to positive control and extract treated groups. The parameters studied were cardiac biomarker enzymes which were Creatine Kinase (CK), Creatine Kinase-MB (CK-MB), Aspartate Transaminase (AST), Alanine Transaminase (ALT) and Lactate Dehydrogenase (LDH). The results showed that S. arvensis at dose of 50 mg/kg b.w. could significantly (P<0.05) reduce the level of CK, CK-MB, AST, ALT, and LDH in myocardial infarcted rats compared to positive control. The increase of the dose of S. arvensis extract was not followed by an increase of its cardioprotective activity. In conclusion, Sonchus arvensis L. leaves extract at dose of 50 mg/kg b.w. has potential to be developed as cardioprotective drug.

scholarly journals Antihypertensive Activity of Leersia hexandra Sw. (Poaceae) Aqueous Extract on Ethanol-Induced Hypertension in Wistar Rat

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Danielle Claude Bilanda ◽  
Yannick Carlos Tcheutchoua ◽  
Paul Désiré Djomeni Dzeufiet ◽  
Daniel Lauré Dongmo Fokou ◽  
Yannick Bekono Fouda ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Aqueous Extract ◽  
Antioxidant Activities ◽  
Hdl Cholesterol ◽  
Wistar Rat ◽  
Atherogenic Index ◽  
Antihypertensive Activity ◽  
Distilled Water ◽  
Hypertensive Rats ◽  
Leersia Hexandra

Leersia hexandra (L. hexandra) is used in traditional medicine to treat many diseases including hypertension. This study aimed to evaluate the curative effects of the aqueous extract of L. hexandra on hypertension. Hypertension was induced in rats by oral administration of ethanol (5 g/kg/day) for five weeks. The animals were divided into 2 groups: one group of 5 rats receiving distilled water (10 mL/kg) and another group of 20 rats receiving ethanol. At the end of the 5 weeks of administration of ethanol, the animals were divided into 4 groups of 5 rats each: one group of hypertensive rats receiving distilled water (10 mL/kg), another one receiving nifedipine (10 mg/kg), and two groups of hypertensive rats receiving L. hexandra at doses of 100 and 200 mg/kg, respectively. The results showed that ethanol induced a significant increase in the mean arterial pressure (MAP) and heart rate of normotensive rats. The administration of the extract (100 and 200 mg/kg) or nifedipine caused a significant decrease of MAP compared to hypertensive rats. Ethanol induced a significant increase of lipid profile, the atherogenic index, creatinine, and transaminase activities. Ethanol also induced a significant decrease in serum HDL-cholesterol and antioxidant markers evaluated. Treatment of hypertensive rats with L. hexandra or nifedipine significantly improved lipid profile, hepatic and renal functions, and antioxidant status. The curative effect of L. hexandra extract on hypertension is probably related to its antihypertensive, hypolipidemic, and antioxidant activities, which justifies its empirical use in the treatment of hypertension.

Surface epithelial ultrastructure of the polycystic ovary in the BB wistar rat

1986 ◽  
Vol 44 ◽  
pp. 252-253
Author(s):  
R. C. Kaufmann ◽  
F. K. Khosho ◽  
K. S. Amankwah
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Wistar Rats ◽  
Polycystic Ovary ◽  
Wistar Rat ◽  
Polycystic Ovaries ◽  
Chemical Diabetes ◽  
Scanning Electron

Diabetes decreases the fertility of females, but the mechanisms are not completely understood. In our investigations, we have found that 13% of the female BB Wistar rats that spontaneously developed chemical diabetes had persistent estrous. In this study the ovaries of these rats were examined by scanning electron microscopy(SEM) and compared to normal-cycling controls as well as to rats that had developed polycystic ovaries(PCO) by exposure to constant 1ight.

Ultrastructural and immunocytochemical studies of the rat hypothalamo-neurohypophysial system processed by rapid freezing and freeze-substitution fixation

1990 ◽  
Vol 48 (3) ◽  
pp. 884-885
Author(s):  
Seiji Shioda ◽  
Yasumitsu Nakai ◽  
Atsushi Ichikawa ◽  
Hidehiko Ochiai ◽  
Nobuko Naito
Keyword(s):  
Osmium Tetroxide ◽  
Freeze Substitution ◽  
Ultrastructural Localization ◽  
Wistar Rat ◽  
Neurosecretory Cells ◽  
Rapid Freezing ◽  
Sodium Metaperiodate ◽  
Tissue Sections ◽  
Ultrathin Sections ◽  
Electron Microscopes

The ultrastructure of neurosecretory cells and glia cells in the supraoptic nucleus (SON) of the hypothalamus and the neurohypophysis (PN) was studied after rapid freezing followed by substituion fixation. Also, the ultrastructural localization of vasopressin (VP) or its carrier protein neurophys in II (NPII) in the SON and PN was demonstrated by using a post-embedding immunoco1loidal gold staining method on the tissue sections processed by rapid freezing and freeze-substitution fixation.Adult male Wistar rat hypothalamus and pituitary gland were quenched by smashing against a copper block surface precooled with liquid helium and freeze-substituted in 3% osmium tetroxide-acetone solutions kept at -80°C for 36-48h. After substituion fixation, the tissue blocks were warmed up to room temperature, washed in acetone and then embedded in an Epon-Araldite mixture. Ultrathin sections mounted on 200 mesh nickel grids were immersed in saturated sodium metaperiodate and then incubated in each of the following solutions: 1 % egg albumin in phosphate buffer, VP or NPII (1/1000-1/5000) antiserum 24h at 4°C, 3) colloidal gold solution (1/20) 1h at 20°C. The sections were washed with distilled waterand dried, then stained with uranylacetate and lead citrate and examined with Hitachi HU-12A and H-800 electron microscopes.

Evaluation of the biochemical and anti-snake venom effects of Calliandra portoricensis extract fractions in wistar rat models

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
PE Ebong ◽  
HP Onyeama ◽  
MU Eteng ◽  
GO Igile ◽  
GE Egbung
Keyword(s):  
Snake Venom ◽  
Wistar Rat ◽  
Rat Models

Віталітетна структура популяцій деяких видів бур’янів у посівах зернових культур

2010 ◽  
Vol 19 (1) ◽  
pp. 123-129 ◽  
Author(s):  
E. M. Tikhonova
Keyword(s):  
Cirsium Arvense ◽  
Setaria Glauca ◽  
Sonchus Arvensis

Досліджено особливості розвитку популяцій сегетальних видів (Cirsium arvense (L.) Scop., Sonchus arvensis L., Melandium album (Mill.) Garke, Setaria glauca (L.) Beauv., Fallopia convolvulus (L.) А. Lоve) у посівах зернових культур (пшениці озимої, жита, ячменю, гречки, гороху), які не оброблялися гербіцидами у господарствах лісостепової зони на території Сумської області. 

The haematological profile with fifty generations of undernutrition cannot be reversed with six generations of a recuperation diet in a wistar rat colony

2019 ◽  
Vol 11 (2) ◽  
pp. 21-24
Author(s):  
M M Karandikar, ◽  
◽  
A R Joshi ◽  
M S Karandikar ◽  
◽  
...  
Keyword(s):  
Wistar Rat ◽  
Haematological Profile
Sign in / Sign up

Export Citation Format

Share Document