Hurdles in mandatory generic medicine prescription

2021 ◽  
Vol 12 (3) ◽  
pp. 115
Author(s):  
Money Gupta ◽  
VerinderJit Singh Virdi ◽  
Rohit Gupta
Keyword(s):  
Generic Medicine ◽  
Medicine Prescription

scholarly journals Assessment of knowledge, attitude and practice of generic medicines among the interns and post graduate dental students: comparison with medical practitioners

2020 ◽  
Vol 9 (9) ◽  
pp. 1398
Author(s):  
Sukhpreet Kaur
Keyword(s):  
Health Care Professionals ◽  
Generic Medicine ◽  
Cross Sectional Study ◽  
Dental Students ◽  
Generic Medicines ◽  
Cross Sectional ◽  
Attitude And Practice ◽  
Validated Questionnaire ◽  
Medicine Prescription ◽  
Knowledge Attitude And Practice

Background: India is one of the highest per capita out-of-pocket health expenditures (62%) country and use of generics can save a lot of money which can be used for other health issues. Lack of knowledge about cost effectiveness of generic medicines among the health-care professionals had led to a low rate of generic medicine prescription. The objective of this study was to explore the knowledge, attitude and practice of dental students towards the generic medicines.Methods: A cross-sectional study was carried out using questions from pretested and validated questionnaire which are applicable to Indian scenario. A 22 items questionnaire were distributed to the participants to assess their knowledge, attitude and practice of generic medicine. All the Interns and MDS students were included in this study. The collected data was analyzed using microsoft excel.Results: 63.4% participants agreed generics can be interchanged with a branded drug. 89.74% participants were aware that bioequivalence studies are conducted by generic manufacturers for all the marketed generic medicines. Mostly participants (78.04%) were of opinion that generic medicines do not produce greater side effects than branded drugs. 54.05% participants reported that they were prescribing generic medicines. 52.38% participants were aware that generic medicine contains the same active substances as that innovator and used at same dose to treat same disease.Conclusions: In our study, we found that the prescribers had a considerable knowledge regarding the concept of generic medicines. However, to further increase the rate of generic medicine prescription training programs on generic medicines should be organized.

scholarly journals Generic prescribing in India: a stumbling block

2020 ◽  
Vol 8 (9) ◽  
pp. 3426
Author(s):  
Sukhpreet Kaur
Keyword(s):  
Health Care ◽  
Clinical Practice ◽  
Health Care Professionals ◽  
Healthcare Setting ◽  
Generic Medicine ◽  
Health Issues ◽  
Regulatory Standards ◽  
Medicine Prescription ◽  
Generic Prescribing ◽  
Set Up

In India, there is 62% out-of-pocket health expenditure per capita and only 15% are covered by health insurance. The use of generics can save a lot of money which can be used for other health issues. But lack of knowledge about cost effectiveness of generic medicines among various health-care professionals had led to a low rate of generic medicine prescription in India. This review aims to identify the barriers in adoption of generic prescribing in clinical practice in India. A systematic literature review was conducted using various healthcare databases such as PubMed and google scholar. The literature search using various combination of keywords retrieved 2360 articles. After excluding duplicates, articles in languages other than English and based on relevance to subject only 15 articles were selected. The barriers to generic prescribing identified from reported literature can be broadly classified based on stakeholders of healthcare setting such as physicians, patients, pharmacist and government policies. The major barriers to generic prescribing identified were negative perception of various stakeholders, lack of awareness of regulatory standards, maturity of health care system, vulnerability of patients, lack of standard guidelines in brand substitution, incentives and influence of drug advertisements. In Indian set up, studies on impact evaluation of generic prescription, emphasizing the quality and cost saving by their use in clinical practice should be conducted. This evidence will help to build the confidence of various stakeholders towards implementing generic prescribing in clinical practice.

scholarly journals Physicians’ Knowledge, Attitude and Practice of Generic Substitution in China: A Cross-Sectional Online Survey

2021 ◽  
Vol 18 (15) ◽  
pp. 7749
Author(s):  
Mingyue Zhao ◽  
Lingyi Zhang ◽  
Zhitong Feng ◽  
Yu Fang
Keyword(s):  
Online Survey ◽  
Generic Substitution ◽  
Generic Drugs ◽  
Final Analysis ◽  
Generic Medicine ◽  
Generic Medicines ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Ordered Logistic Regression ◽  
Tertiary Hospitals

The purpose of this study is to investigate physicians’ knowledge, attitudes and practice of generic medicine substitutions in China. We conducted a cross-sectional online questionnaire survey on physicians from secondary or tertiary hospitals in China from 2020 December to 2021 April. Descriptive statistical and ordered logistic regression were used for analysis. A total of 1225 physicians were included in the final analysis, and only 330 (26.94%) of them scored 4 or above in the knowledge part, which means that the physicians have a good knowledge of generic substitutions. Of the total, 586 (47.83%) agreed or strongly agreed that generic drugs could be substituted for originator drugs and 585 (47.75%) always or often prescribed generic medicines. The percentage of physicians with a positive attitude toward or that practice prescribing generic medicine is below 50%, which needs to be improved in China. Physicians’ knowledge, their attitude toward generic substitution, if familiar with the policy of generic substitution, and incentives for prescribing generic medicines are influencing factors for the practice of generic substitution. Our studies show that the practice of generic substitution by physicians could be improved by several measures in China. We suggested that the physicians should be taught more about the bulk-buy policy and the generic-originator equivalence evaluation policy. Moreover, government incentives to promote generic substitution should be established. Our study also suggested that physicians with less working experience and female physicians should learn more about generic substitution.

scholarly journals Perspectives of pharmaceutical stakeholders on determinants of medicines accessibility at the primary care level

2021 ◽  
Vol 96 (1) ◽  
Author(s):  
Hoda Ibrahim Rizk ◽  
Monira Mahmoud Elkholy ◽  
Abeer Abdou Barakat ◽  
Raghda Mostafa Mostafa Elsayed ◽  
Shaimaa A. M. Abd El Fatah
Keyword(s):  
Health System ◽  
Access To Medicines ◽  
Generic Medicine ◽  
Essential Medicines ◽  
Cross Sectional ◽  
Urban Group ◽  
Rural And Urban ◽  
External Stakeholders ◽  
Assessment Approach ◽  
The Government

Abstract Background Equitable access to essential medicines of maintained efficacy, safety, quality, and cost-effectiveness must be ensured by a well-functioning health system. This study aims to identify the determinants of patients’ access to medicines at the primary health care (PHC) level from the perspectives of various (internal and external) stakeholders of the pharmaceutical system. Methods The study employed both quantitative and qualitative components. Quantitative component applied a descriptive a cross-sectional design and qualitative component applied an in-depth interview design. It was a health system research conducted at two (PHC) facilities (one urban and the other rural) in Egypt. It inquired upon political, economic, and managerial aspects of the pharmaceutical system utilizing the “Health System Assessment Approach: a How-To Manual” and the “WHO operational package for assessing, monitoring and evaluating country pharmaceutical situations.” Results Analysis of the quantitative data extracted from the cross-sectional component with external stakeholders (patients) revealed that about one-third of patients in both facilities were unable to pay for the medicine. Patients in both settings took less than an hour to reach the PHC facility. The Percent of patients who believe that the private pharmacies’ medicine is better than the PHC one was significantly higher in rural than urban group (24% and 10% respectively) and the percent of medicines dispensed was 50% and 66.7% in rural and urban groups respectively. Analysis of the qualitative data extracted from in-depth interviews with internal stakeholders (key informants from regulatory agencies, pharmaceutical industry, academia, pharmacists, and physicians) were summarized utilizing Strengths-Weaknesses-Opportunities-Challenges (SWOC) analysis approach. Various viewpoints toward the determinants of patients’ access to medicines were disclosed. Conclusions The Percent of medicines dispensed was insufficient in both rural and urban facilities. There is a need to invest in building trust in generic medicine quality in the government health facilities focusing on improving medicine availability and ensuring enough amounts of high-quality drugs. Although there are drug committees in the two studied PHC facilities for demonstrating the prescribing and dispensing policies, yet the system required to enforce these policies is still deficient.

P6147Access to essential cardiovascular medicines in Kerala, the state with the highest cardiovascular disease burden in India

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
G Satheesh ◽  
S Puthean ◽  
M Ansil ◽  
M K Unnikrishnan ◽  
A Sharma ◽  
...  
Keyword(s):  
Public Sector ◽  
Private Sector ◽  
Premature Mortality ◽  
Generic Medicine ◽  
Essential Medicines ◽  
World Health ◽  
Healthcare Needs ◽  
Consumer Prices ◽  
Majority Population ◽  
Government Worker

Abstract Introduction The 2030 Agenda for Sustainable Development has prioritized the reduction of premature mortality due to NCDs – including cardiovascular diseases (CVD) - by a third. To achieve this goal, countries must achieve 80% availability of affordable essential medicines. Essential medicines as identified by the World Health Organization are those that meet the priority healthcare needs of majority population. Globally, India has the second highest CVD burden with over 1.7 million deaths annually, with the highest CVD morbidity and mortality rate in Kerala. Purpose To evaluate the availability, prices and affordability of essential CVD medicines in Kerala state to facilitate implementation of informed public health policy. Methods Using WHO/HAI methodology, we obtained data on availability and prices for 25 essential CVD medicines in a representative sample of 7 public-sector hospitals (survey anchors) and 37 private retail pharmacies located near the survey anchors in four districts. Additionally, we obtained the data from 10 government-subsidized discount pharmacies. We report availability as percentage of surveyed facilities where a given medicine was found. Median prices ratios (MPRs) were calculated by comparing consumer prices to the MSH International Reference Prices (IRPs). Medicines were considered affordable if the monthly supply costs less than one-day's wage of the lowest paid government worker. Results In the public-sector facilities (hospital and discount pharmacies combined), the mean (SD) availability of the surveyed CVD medicines was 52% (35.3%) for generic and 35.3% (20.7%) for originator brand (OB) version. 28% of surveyed medicines (including amlodipine, clopidogrel, losartan, metformin) were available in over 80% pharmacies. 12% (captopril, streptokinase and glyceryl trinitrate) were not available in any of the facilities. In the private sector, mean (SD) availability of generic and OB versions was 64.4% (37.2%) and 43.7% (34.6%), respectively. MPR was 1.28 [range: 0.02 (insulin NPH) – 16.7 (simvastatin)] for both lowest-priced generics (LPG) and most-sold generics (MSG). The lowest paid government worker in Kerala would spend 0.06 - 3.48 days' wages for the monthly supply of essential CVD medicines in the private sector. In government-subsidized discount pharmacies, mean availability was 49.3%. The generic medicine prices were 74% lower than in the private sector. Conclusions Availability of essential CVD medications in both public and private sector pharmacies fall short of the 80% target. In the private-sector, many essential CVD medications seem unaffordable especially considering the polypharmacy among CVD patients. Introducing policies to improve medicine availability in government-subsidized discount pharmacies is crucial in tackling Kerala's ever-increasing CVD burden.

scholarly journals Assessment of the Aromatase Inhibitory Activity of Ma-Huang-Tang (MHT) and Its Active Compounds

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Dong Ho Jung ◽  
Joo Tae Hwang ◽  
Bo-Jeong Pyun ◽  
Song Yi Yu ◽  
Byoung Seob Ko
Keyword(s):  
Herbal Medicines ◽  
Inhibitory Effect ◽  
Aromatase Activity ◽  
Cytochrome P450 Enzyme ◽  
Active Components ◽  
Glycyrrhizae Radix ◽  
Potent Inhibition ◽  
P450 Enzyme ◽  
Medicine Prescription ◽  
Ma Huang

Aromatase, a cytochrome P450 enzyme that converts androgens into estrogens, is an important drug target for hormone-dependent diseases. The purpose of this study was to elucidate the aromatase inhibitory effects of Ma-Huang-Tang (MHT), a traditional Korean herbal medicine prescription, and to identify its active ingredients. In this study, the inhibitory effect of MHT on aromatase activity was observed using dibenzylfluorescein (DBF) and KGN cells, and the dose-dependent effect of MHT was verified (IC50 values of 251 μg/mL and 246 μg/mL as determined by the two methods, respectively). Furthermore, among the six herbal medicines that constitute MHT, Ephedrae Herba, Cinnamomi Ramulus, and Glycyrrhizae Radix et Rhizoma showed the most potent inhibition of aromatase activity. Furthermore, upon identification of the active MHT compounds, three markers from Glycyrrhizae Radix et Rhizoma, liquiritin (5), liquiritin apioside (6), and liquiritigenin (7), were verified (IC50 values of 530 μM, 508 μM, and 1.611 mM and 499 μM, 522 μM, and 1.41 mM as determined by the two methods, respectively). In addition, their contents were confirmed to be 15.58, 19.80, and 2.22 mg/g, respectively, by HPLC/DAD analysis. These results indicate that the aromatase inhibitory effect of MHT results from the synergistic action of its active components and that MHT has potential as a preventive agent against aromatase activity.

CORDIAL CYBORG

2021 ◽  
pp. 29-31
Author(s):  
Saumya Jaiswal ◽  
Shivangi Tiwari ◽  
Vivek Kumar Tripathi ◽  
Ajay Sharma
Keyword(s):  
Direct Contact ◽  
Medical Robotics ◽  
Medical Applications ◽  
Collaborative Robotics ◽  
Medical Robots ◽  
The Past ◽  
Medicine Prescription ◽  
Hospital Stays ◽  
Return Home ◽  
Spread Of Infection

1. What are robots used in healthcare? Areas within healthcare which are starting to use robots include: telepresence, rehabilitation, medical transportation, sanitization and prescription dispensing. But we are most interested in collaborative robotics. We will be discussing the COBOT(Cordial Robot) applications. Most modern healthcare robots are especially designed for their target applications. 2. Is it possible to use robotics in medicine? Robotics in medicine can happen in many ways, here are some. Healthcare has been predicted as “a promising industry for robotics” for the past 45 years or more. Since as far back as 1974, researchers have been looking for ways to incorporate robotics into medical applications. 3. Is there a need for more surgery/telepresence/rehabilitation/medical transportation/sanitation and disinfection/medicine prescription dispensing robots? There is denitely a need for many more surgery robots, laparoscopic, endoscopic and nanorobots, as the technology allows more functionalities with miniature propulsion mechanisms. M.A. Zenati, M. Mahvash, from the science of medical robotics, 2012. 4. How are medical robots used to treat patients, reduce contact, and cure pain? Using the medical robots reduces the direct contact between the doctor and the patient, helps in reducing pain, by minimizing the need for more medication and longer hospital stays, allowing the person to return home by the therapy sooner without any spread of infection.

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