Thyroid disorders in children and adolescents: Systematic mapping of global research over the past three decades

2021 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
Devi Dayal ◽  
BrijMohan Gupta ◽  
Atul Gupta
1997 ◽  
Vol 87 (2) ◽  
pp. 66-69 ◽  
Author(s):  
A Glockenberg ◽  
E Sobel ◽  
JF Noël

Nonossifying fibroma is a benign, lytic lesion that occurs in young children and adolescents. Radiographically, the lesion is multilocular and sharply demarcated. It often occurs at the metaphyseal region of long bones of the lower extremity and is usually eccentrically located. Four cases of nonossifying fibroma occurring during the past 7 years are presented with a review of the literature.


Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Jessica G Woo ◽  
Lydia A Bazzano ◽  
Trudy L Burns ◽  
Stephen R Daniels ◽  
Terence Dwyer ◽  
...  

Introduction: The prevalence of childhood obesity has increased dramatically over the past several decades, but it is unclear whether children and adolescents with obesity are experiencing more or fewer cardiometabolic risks from obesity now compared with several decades ago. This study leverages data from over 2600 children and adolescents with obesity born from 1951-1996 to determine whether relationships of obesity with cardiometabolic risk have changed over time. Methods: The first study visit, age 3-19, was used to classify individuals by era of birth (quartiles: 1951-1963, 1964-1969, 1970-1974, 1975-1996), weight status (obesity defined as BMI>CDC 95 th %ile and <120% of the 95 th %ile), high BP (SBP or DBP>95 th %ile), high total cholesterol (TC>170 mg/dl), high LDL-C (>110 mg/dl), high triglycerides (TG>100 mg/dl), high glucose (>100 mg/dl), and low HDL-C (<40 mg/dl males, <50 mg/dl females). Participants with obesity (excluding severe obesity) were included in this analysis. Logistic regressions were adjusted for age, sex, race and study cohort to calculate odds ratios relative to the most recent era of birth (1975-1996). Results: The prevalence of childhood obesity increased from 6.1% in the earliest birth era to 7.7% in the most recent (p<0.0001). The adjusted odds of children with obesity having high TC (p<0.0001), high TG (p<0.0001), and high BP (p=0.003) were half as likely among children born between 1964-69 or 1970-74, compared with the most recent birth era (Table). The odds of children with obesity having high LDL (p=0.59), low HDL (p=0.17) or high glucose (0.33) did not differ across birth eras. Conclusions: Childhood obesity in more recent decades has not only become more prevalent, but is associated with greater risks of high TC, high TG and high BP. However, the risks of high LDL, low HDL and high glucose have not significantly changed among children with obesity who were born between 1951 and 1996. Thus, comparisons of children or adolescents with obesity across eras should consider these differing risk profiles.


2020 ◽  
Vol 47 (5) ◽  
pp. 379-384
Author(s):  
Florian Piekarski ◽  
Andrea Steinbicker ◽  
Kai Zacharowski ◽  
Patrick Meybohm

Introduction: In recent years, resource-saving handling of allogeneic blood products and a reduction of transfusion rates in adults has been observed. However, comparable published national data for transfusion practices in pediatric patients are currently not available. In this study, the transfusion rates for children and adolescents were analyzed based on data from the Federal Statistical Office of Germany during the past 2 decades. Methods: Data were queried via the database of the Federal Statistical Office (Destasis). The period covered was from 2005 to 2018, and those in the sample group were children and adolescents aged 0–17 years receiving inpatient care. Operation and procedure codes (OPS) for transfusions, procedures, or interventions with increased transfusion risk were queried and evaluated in detail. Results: In Germany, 0.9% of the children and adolescents treated in hospital received a transfusion in 2018. A reduction in transfusion rates from 1.02% (2005) to 0.9% (2018) was observed for the total collective of children and adolescents receiving inpatient care. Increases in transfusion rates were recorded for 1- to 4- (1.41–1.45%) and 5- to 10-year-olds (1.24–1.33%). Children under 1 year of age were most frequently transfused (in 2018, 40.2% of the children were cared for in hospital). Transfusion-associated procedures such as chemotherapy or machine ventilation and respiratory support for newborns and infants are on the rise. Conclusion: Transfusion rates are declining in children and adolescents, but the reasons for increases in transfusion rates in other groups are unclear. Prospective studies to evaluate transfusion rates and triggers in children are urgently needed.


1989 ◽  
Vol 34 (9) ◽  
pp. 879-883 ◽  
Author(s):  
Margaret Whitfield

Female sexuality (meaning sexual desire, excitement and orgasm) has been of considerable interest in psychiatry. Women's efforts to define and legitimize their own experience of their sexuality have increased in the past 25 years. However, the integration of these new views into the body of psychiatric (especially psychoanalytic) theory has not occurred very actively or successfully. Very little is known about the development of sexuality in childhood and adolescence. This paper looks at various behaviours, interests and events in women's lives that might reveal something about the development of their sexuality. The literature on female masturbation is reviewed and some sex differences highlighted. The literature on interest in babies, the wish to have babies, and menarche is explored for possible associations with sexuality. Rather than sexuality being a central organizer of experience, it seems quite possible that experience is an organizer of sexuality. Therefore, to better understand female sexuality we need to consider the impact of experiences during childhood and adolescence.


1978 ◽  
Vol 93 (1) ◽  
pp. 57-61 ◽  
Author(s):  
Nancy J. Hopwood ◽  
Bruce S. Rabin ◽  
Thomas P. Foley ◽  
Robert L. Peake

Computers ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 10 ◽  
Author(s):  
Johannes Grohmann ◽  
Nikolas Herbst ◽  
Avi Chalbani ◽  
Yair Arian ◽  
Noam Peretz ◽  
...  

Failure prediction is an important aspect of self-aware computing systems. Therefore, a multitude of different approaches has been proposed in the literature over the past few years. In this work, we propose a taxonomy for organizing works focusing on the prediction of Service Level Objective (SLO) failures. Our taxonomy classifies related work along the dimensions of the prediction target (e.g., anomaly detection, performance prediction, or failure prediction), the time horizon (e.g., detection or prediction, online or offline application), and the applied modeling type (e.g., time series forecasting, machine learning, or queueing theory). The classification is derived based on a systematic mapping of relevant papers in the area. Additionally, we give an overview of different techniques in each sub-group and address remaining challenges in order to guide future research.


2015 ◽  
Vol 40 (3) ◽  
pp. 232-241 ◽  
Author(s):  
Russell Pratt ◽  
Cyra Fernandes

Over the past three decades, an accepted “given” of adolescent sexually abusive behaviour assessment and treatment has been that the more serious the sexual acts committed, the more entrenched that adolescent's behaviours are likely to be, with a likely progression from minor assaults through to more serious, intrusive acts. We assume youth engaging in the sexually abusive behaviour may have become both desensitised to the harm they are causing, whilst needing to engage in more severe offences to gain the level of arousal originally achieved through lesser acts. This conceptualisation suggests a somewhat causal relationship between the duration of the sexually abusive behaviour; the severity of the behaviour and the length of treatment required to manage and treat the issue.Has pornography consumption potentially impacted the assessment and treatment of youth who sexually harm? Does a relationship exist between the severity and the entrenchment of the sexually assaultive acts committed, or has viewing pornography and re-enacting what has been viewed altered this relationship? This article explores a number of these themes and questions.


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