scholarly journals Adenomatoid Tumor of Testis

2009 ◽  
Vol 2 ◽  
pp. CPath.S3091 ◽  
Author(s):  
Waqas Amin ◽  
Anil V. Parwani
Keyword(s):  
Wilms Tumor ◽  
Frozen Section ◽  
Benign Tumors ◽  
Excision Biopsy ◽  
Clinical Consideration ◽  
Fibrous Stroma ◽  
Beta Hcg ◽  
Columnar Cells ◽  
Slow Growing ◽  
Vacuolated Cytoplasm

Adenomatoid tumors are responsible for 30% of all paratesticular masses. These are usually asymptomatic, slow growing masses. They are benign tumors comprising of cords and tubules of cuboidal to columnar cells with vacuolated cytoplasm and fibrous stroma. They are considered to be of mesothelial origin supported by histochemical studies and genetic analysis of Wilms tumor 1 gene expression. Excision biopsy is both diagnostic and therapeutic procedure. The main clinical consideration is accurate diagnosis preventing unnecessary orchiectomy. Diagnostic studies include serum tumor markers (negative alpha fetoprotein, beta HCG, LDH) ultrasonography (hypoechoic and homogenous appearance) and frozen section.

scholarly journals Schwannoma in oropharynx: a rare site posing diagnostic challenge

2017 ◽  
Vol 5 (11) ◽  
pp. 5066
Author(s):  
Deepshikha Rana ◽  
Sujata Raychaudhuri ◽  
Nimisha Sharma
Keyword(s):  
Head And Neck ◽  
Neck Region ◽  
The Body ◽  
Benign Tumors ◽  
Excision Biopsy ◽  
Diagnostic Challenge ◽  
Nerve Sheath Tumors ◽  
S 100 ◽  
Rare Site ◽  
Slow Growing

Schwannomas are benign nerve sheath tumors. These arise from Schwann cells of the neural sheath. Intra oral region is a relatively uncommon site of these tumors. They are solitary, slow growing, smooth surfaced, usually asymptomatic, and encapsulated tumors, about 25% of all schwannomas are located in the head and neck, but only 1% show intraoral origin. A 22-year-old female came with dysphagia since, 3 years. FNAC was not feasible and so excision biopsy of the lesion was performed. Histopathology revealed schwannoma like picture and it was confirmed with diffuse S-100 positivity on immunohistochemistry. Hence, finally confirming schwannoma of the oropharyngeal region. Schwannomas can be found anywhere in the body but a quarter of all occur in the head and neck region. Intraorally its percentage is only 1% with tongue being the commonest. Pharyngeal presentations of schwannoma are rare. Schwannomas are benign tumors having excellent prognosis. Basically, this case report is important as these very rarely occur in the oropharyngeal region and it’s a must to consider them in the differential diagnosis of lesions at this site.

scholarly journals Giant Parotid Pleomorphic Adenoma with Atypical Histological Presentation and Long-Term Recurrence-Free Follow-Up after Surgery: A Case Report and Review of the Literature

2020 ◽  
Vol 2020 ◽  
pp. 1-18
Author(s):  
Mohammed AlKindi ◽  
Sundar Ramalingam ◽  
Lujain Abdulmajeed Hakeem ◽  
Manal A. AlSheddi
Keyword(s):  
Pleomorphic Adenoma ◽  
Surgical Management ◽  
Early Stage ◽  
English Literature ◽  
Benign Tumors ◽  
Adjuvant Radiation ◽  
Extracapsular Dissection ◽  
Slow Growing

Salivary gland tumors (SGT) comprise 3% of all head and neck tumors, are mostly benign, and arise frequently in the parotid gland. Pleomorphic adenoma (PA) is the commonest SGT, representing 60-70% of all benign parotid tumors. Clinically, parotid PA presents as irregular, lobulated, asymptomatic, slow-growing preauricular mass, involving both superficial and deep lobes, and could grow to gigantic proportions. Histologically, PA has epithelial and mesenchymal elements in chondromyxoid matrix and is managed surgically. Based on a review of 43 cases reported in English literature since 1995, giant parotid PA is reported as large as 35 cm (diameter) and 7.3 kg (resected weight). Although rare, 10 cases of malignant transformation were reported in the review. Surgical management included extracapsular dissection (ECD), superficial parotidectomy, and total parotidectomy for benign tumors, and adjuvant radiation or chemotherapy for malignant tumors. We further present the case of a 36-year-old healthy male with slow-growing and asymptomatic giant parotid PA, of 4-year duration. The patient presented with firm, lobulated preauricular swelling, provisionally diagnosed as PA based on radiographic and cytological findings. The tumor was resected through ECD, and the patient had uneventful postoperative recovery and a 7-year recurrence-free follow-up period. Histological examination revealed epimyoepithelial proliferation punctuated by chondromyxoid areas, with extensive squamous metaplasia and keratin cysts. To the best of knowledge from indexed literature, giant parotid PA is rarely reported in Saudi Arabia. In addition to its rarity, this case is reported for its benign nature despite atypical histological presentation, successful surgical management without complications, and long-term recurrence-free follow-up. Based on this report, clinicians must be aware of atypical histological presentations associated with PA and plan suitable surgical management and follow-up to avoid morbidity. Nevertheless, attempts must be made to diagnose and manage these lesions at an early stage and before they reach gigantic proportions.

scholarly journals Mucinous cystadenomas of the liver

2013 ◽  
Vol 141 (3-4) ◽  
pp. 173-177
Author(s):  
Radoje Colovic ◽  
Nikica Grubor ◽  
Miodrag Jovanovic ◽  
Marjan Micev ◽  
Natasa Colovic ◽  
...  
Keyword(s):  
Frozen Section ◽  
Benign Tumors ◽  
Appropriate Treatment ◽  
Head Of The Pancreas ◽  
Malignant Alteration ◽  
Mucinous Cystadenomas ◽  
The Right ◽  
Healthy Liver ◽  
Single Lesion ◽  
Partial Excision

Introduction. Biliary cystadenomas of the liver are rare benign tumors prone to malignant alteration so that a total excision is recommended. Objective. The aim of the paper is to present our experience in treatment and to evaluate whether a simple ablation represents the appropriate treatment. Methods. Over a 10?year period 25 patients (24 women) of the average age of 58 years suffering from cystadenomas of the liver, 18 in the right, 4 in the left and 3 in both lobes of the liver were operated. Twenty?three patients had a single lesion, while two patients had 3 and 6 lesions, respectively. Pain was present in 20, occasional vomiting in 4, discomfort in 2 and a sense of fullness in 2 patients. Three patients were jaundiced, 1 due to cystadenoma of the liver, 2 due to concomitant tumors of the head of the pancreas, while 5 patients had concomitant diseases. Results. A total ablation was performed in 22 patients, left lateral bisegmentectomy in 1 and partial excision in 2 patients. Six additional procedures were performed. Five cystadenomas of the liver had ?ovarian like? stroma, all in women. A focal malignant alteration was found in 2 patients aged 66 and 79 years, respectively. Recurrence was registered in 1 female patient in whom a partial excision had been done. Two patients with concomitant malignancy and 1 patient who developed malignant histiocytosis six months after surgery, died after 1, 2 and 3 years, respectively. Conclusion. Biliary cystadenomas of the liver may be misdiagnosed as simple liver cysts, so that ?frozen section? histology is highly recommended. In most cases the tumor may be successfully treated by ablation up to the healthy liver tissue. Major liver resections are rarely necessary.

scholarly journals Asymptomatic nodule on face: Dermoscopic and histopathological clue for diagnosis

2020 ◽  
Vol 17 (1) ◽  
pp. 63-65
Author(s):  
Anisha Joshi ◽  
Deeptara Pathak Thapa
Keyword(s):  
Head And Neck ◽  
Peripheral Nerves ◽  
Neck Region ◽  
Surgical Excision ◽  
Benign Tumors ◽  
Complete Excision ◽  
Head And Neck Region ◽  
The Common ◽  
Slow Growing ◽  
Rare Diagnosis

Schwannomas/ neurilemmomas are benign tumors of nerve sheath arising from Schwann cells that form myelin sheath around peripheral nerves. They are usually solitary, slow growing and encapsulated lesions. Head and neck are the common sites. We report a case of a 38 years old Nepalese female who had presented with a solitary asymptomatic, slow growing nodule on the left side of the chin for the last three years. Dermoscopy of the lesion revealed arborizing vessels with brownish pigmentation overlying a whitish to pinkish background. Complete excision of the lesion was performed. Histopathological evaluation of the lesion revealed schwannoma. Though schwannomas are a rare diagnosis, they should be considered as a differential diagnosis of any unilateral, asymptomatic, slow growing nodule in the head and neck region. Dermoscopy is a useful tool which helps to differentiate schwannoma from other lesions. Histopathology is the gold standard for diagnosis and the treatment of choice is surgical excision.  

Parosteal Osteosarcoma

2014 ◽  
Vol 138 (5) ◽  
pp. 694-699 ◽  
Author(s):  
Jen-Fan Hang ◽  
Paul Chih-Hsueh Chen
Keyword(s):  
Benign Tumors ◽  
Parosteal Osteosarcoma ◽  
Prognostic Variables ◽  
Pathologic Features ◽  
Conventional Osteosarcoma ◽  
Microscopic Morphology ◽  
Slow Growing ◽  
Diagnostic Pitfalls ◽  
Metaphyseal Region ◽  
Better Than

Parosteal osteosarcoma is a rare malignant bone tumor arising from the bone cortical surface. It most commonly occurs in young women over the metaphyseal region, especially the long bones near the knee joint. Patients usually report a slow-growing mass for years. The tumor is characterized by its bland microscopic morphology, prone to be misdiagnosed as other benign tumors. In the absence of dedifferentiation, the prognosis is generally better than that of conventional osteosarcoma. Recent studies demonstrated distinctive cytogenetic abnormality resulting in amplification of the CDK4 and MDM2 genes, which may serve as markers for molecular diagnosis. In this article, we review the clinical, radiologic, and pathologic features of parosteal osteosarcoma and identify some diagnostic pitfalls, discuss the prognostic variables, and update recent molecular advances and their application in the diagnosis.

scholarly journals Cervicomedullary Ganglioglioma in a Child – A Case Report

2018 ◽  
Vol 119 (2-3) ◽  
pp. 122-127
Author(s):  
Eshagh Bahrami ◽  
Morteza Taheri ◽  
Feyzollah Ebrahimniya
Keyword(s):  
Spinal Cord ◽  
Cervical Spinal Cord ◽  
Frozen Section ◽  
Young Patients ◽  
Neurological Status ◽  
Upper Cervical ◽  
Magnetic Resonance Imaging Mri ◽  
Slow Growing ◽  
Section Report

Ganglioglioma is a benign slow-growing neoplasm that most frequently occurs at the supratentorial region. Nevertheless, there are occasional reports of ganglioglioma occurring in the brainstem and spinal cord. Here we report a rare case of the craniocervical ganglioglioma. A 3.5-year-old male, presented with severe progressive quadriparesis, gait disturbance, and sphincter deficit. Physical examination demonstrated the quadriparesis, associated with positive Hoffman, Babinski, and clonus signs, and increased respond of deep tendon reflexes. Magnetic resonance imaging (MRI) demonstrated an ill-defined mass within medulla and upper cervical spinal cord, which was hypo to iso signal on T1, heterogeneous iso to hypersignal on T2 and demonstrated marked bright enhancement on T1 with gadolinium (Gad) injection. On surgery, the mass had a soft texture, ill-defined border, and grey to brown appearance. According to the frozen section report, and due to the absence of the tumour-neural parenchymal interference, only decompression of the tumour and expansile duraplasty were performed. The histopathology revealed ganglioglioma. On last follow-up 14 months after surgery, the patient was asymptomatic and neurological status was improved. The craniocervical MRI demonstrated the tumour that did not grow. Although it is rare, the ganglioglioma should be in the differentiated diagnoses of tumours with compatible clinical and radiologic features even in the unusual locations, especially in the pediatric and young patients. Safety surgical resection should be considered in these patients, whenever possible. In the case of partial resection, that is common in the tumours located within functionally critical structures, long close follow-up rather than radiation therapy is required.

scholarly journals To Determine the Accuracy of Frozen Section in the Management of Ovarian Tumours

2021 ◽  
Vol 10 (11) ◽  
pp. 793-797
Author(s):  
Sarmishta Murugesan ◽  
Alka Natrat Nadar
Keyword(s):  
Frozen Section ◽  
Paraffin Section ◽  
Research Centre ◽  
Benign Tumors ◽  
Malignant Tumours ◽  
Good Tool ◽  
Ovarian Tumours ◽  
Diagnosis And Classification ◽  
Histopathological Report

BACKGROUND Frozen section done during surgery provides a valuable tool in the diagnosis and classification of tumours into benign, borderline and malignant. In this study, we evaluated the intraoperative findings and the accuracy of the frozen section and compared it with the final histopathology report. METHODS A retrospective study was done in the Department of Obstetrics and Gynecology in Sri Ramachandra University and Research Centre from January 2017 to January 2020, for a period of 3 years and data was taken from the patients who underwent surgery-staging laparotomy for ovarian masses along with frozen section in the diagnosis of their tumor. The final histopathology report is the gold standard for detection of ovarian tumours. The accuracy of the frozen section was compared with the final histopathological report on paraffin section. RESULTS There was a total of 109 cases during the study period of 3 years. Out of the total, frozen section showed 55 malignancy cases, 7 cases were borderline, and 47 cases were benign tumors; whereas the final histopathology report showed 51 malignant cases, 9 borderline cases, and 49 cases were benign tumors. This shows that frozen section has almost 97 % accuracy. CONCLUSIONS Frozen section is a very good tool in the diagnosis of tumour whether benign, borderline or malignant and when compared with the final histopathological report gives good accuracy. The diagnosis given during surgery is helpful in the further management of patients according to the stage of the tumour. KEY WORDS Frozen Section, Benign, Borderline, Malignant tumours, Final Histopathological Report

scholarly journals Intractable Trigeminal Neuralgia Secondary to Osteoma of the Clivus: A Case Report and Literature Review

2022 ◽  
Author(s):  
Ebtesam Abdulla ◽  
Krishna Das ◽  
Joseph Ravindra ◽  
Tejal Shah ◽  
Sara George
Keyword(s):  
Trigeminal Neuralgia ◽  
Pressure Effect ◽  
Benign Tumors ◽  
Radiographic Images ◽  
Patient Reported ◽  
Magnetic Resonance Imaging Mri ◽  
The Right ◽  
Slow Growing ◽  
Serial Observation

AbstractSkull base osteomas (SBOs) are benign tumors that are frequently detected on radiographic images by coincidence. They are known for being slow-growing tumors and rarely symptomatic. The therapeutic approach for SBOs can differ substantially. Depending on the symptoms, size, and location of the tumor, this can range from serial observation to vigorous surgical extirpation. Clival osteoma is extremely rare. We report a case of clival osteoma, causing intractable trigeminal neuralgia due to the pressure effect on the trigeminal nerve at Meckel's cave. We also provide a review of pertinent literature. A 37-year-old woman presented with intractable trigeminal neuralgia. Cranial magnetic resonance imaging (MRI) demonstrated a large, lobulated, extra-axial lesion involving the right cerebellopontine angle and epicentering the clivus. Pathologically, the specimen was proven to be osteoma. The patient reported complete symptom resolution over a 4-year follow-up period. To the best of the authors' knowledge, this is the first clinical case of intractable trigeminal neuralgia due to clival osteoma.

scholarly journals HISTOPATHOLOGICAL SPECTRUM OF NEOPLASTIC LESIONS OF KIDNEY- A THREE YEARS STUDY

2021 ◽  
Vol 5 (6) ◽  
Author(s):  
Saket Sarswat ◽  
Vimlesh . ◽  
D.P. Soni
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Wilms Tumor ◽  
Malignant Tumors ◽  
Pathological Process ◽  
Benign Tumors ◽  
Older Individuals ◽  
Neoplastic Lesions ◽  
Paediatric Age

Background: Kidney can be involved in various pathological process. Both benign & malignant tumors can occur in the kidney. They arise from different components of renal parenchyma, notably tubular epithelium.1 99 percent of renal neoplasms are malignant, with renal cell carcinoma and wilm’s tumor being the most common2. Men have higher incidence than women (approximately 1.6:1) and vast majority are diagnosed after 65 years of age. Material and methods: Prospective and retrospective study from January 2017 to December 2019 in the Department of Pathology. Results: The study comprised of 67 cases of neoplastic conditions, out of which 63 cases are malignant and only 4 cases were recorded as benign. Conclusion: Malignant tumors far more common than benign lesions. In adults and older individuals, renal cell carcinoma was most common while among paediatric age group, wilms tumor was most common. Benign tumors were uncommon. Keywords: Kidney, renal cell carcinoma, wilms tumor

scholarly journals Neurofibroma of lumbosacral region: a case report

2019 ◽  
Vol 7 (5) ◽  
pp. 1948
Author(s):  
Elfiah . ◽  
Syaifullah Asmiragani
Keyword(s):  
Case Report ◽  
Peripheral Nerve ◽  
Vertebral Body ◽  
Cervical Cord ◽  
Benign Tumors ◽  
Lumbosacral Region ◽  
Sacral Region ◽  
Nerve Sheath ◽  
Sensory Changes ◽  
Slow Growing

Neurofibromas are benign tumors of the peripheral nerve sheath. Spinal neurofibroma often asymptomatic. Symptoms may present include sensory changes. Neurofibroma mostly encountered cervical cord, difficult to distinguish from schwannomas. This slow growing tumor remodel the bone resulting pedicle thinning and posterior vertebral body scalloping. MRI shows hyperintense rim. Although this highly suggestive neurofibroma, occasionally also seen in schwannoma and malignant PNST. Treatment choice for symptomatic lesions is surgery. We are reporting a case of neurofibroma in the 5th lumbar and 1st sacral region.

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