scholarly journals Evaluation of the relationship between neutrophil lymphocyte ratio and the most common bacterial urinary tract infections after transplantation

2019 ◽  
Vol 120 (02) ◽  
pp. 161-165 ◽  
Author(s):  
H. Kazimoglu ◽  
E. Uysal ◽  
M. Dokur ◽  
H. R. Gunerkan
Diagnostics ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 7
Author(s):  
Tomislav Meštrović ◽  
Mario Matijašić ◽  
Mihaela Perić ◽  
Hana Čipčić Paljetak ◽  
Anja Barešić ◽  
...  

The current paradigm of urinary tract infection (UTI) pathogenesis takes into account the contamination of the periurethral space by specific uropathogens residing in the gut, which is followed by urethral colonization and pathogen ascension to the urinary bladder. Consequently, studying the relationship between gut microbiota and the subsequent development of bacteriuria and UTI represents an important field of research. However, the well-established diagnostic and therapeutic paradigm for urinary tract infections (UTIs) has come into question with the discovery of a multifaceted, symbiotic microbiome in the healthy urogenital tract. More specifically, emerging data suggest that vaginal dysbiosis may result in Escherichia coli colonization and prompt recurrent UTIs, while urinary microbiome perturbations may precede the development of UTIs and other pathologic conditions of the urinary system. The question is whether these findings can be exploited for risk reduction and treatment purposes. This review aimed to appraise the three aforementioned specific microbiomes regarding their potential influence on UTI development by focusing on the recent studies in the field and assessing the potential linkages between these different niches, as well as evaluating the state of translational research for novel therapeutic and preventative approaches.


2015 ◽  
Vol 10 (3) ◽  
pp. 202-204 ◽  
Author(s):  
Kirtishri Mishra ◽  
Christopher S Elliott

Ectopic ureters are a found in one of every 2000–4000 people. This abnormality can present with urinary tract infections, haematuria, and occasionally incontinence. Ectopic ureters traditionally follow the Weigert-Meyer Law, which describes the relationship of the lower and upper renal moieties. It states that the lower renal pole drains into a laterocranial ureteral orifice (and may reflux), while the upper renal pole drains into a mediocaudal ureteral orifice (and may be obstructed). If a duplicated ureter does not insert into the bladder, it by rule, originates from the upper pole. We present a case of a 42-year-old male who was incidentally found to have what appears to be an ectopic ureter draining from the lower renal pole into a structure contained in the scrotum, hence violating the Weigert-Meyer law.


2020 ◽  
Vol 3 (2) ◽  
pp. 23-30
Author(s):  
Tiarnida Nababan

Urinary tract infection (UTI) is a result of the development of microorganisms in the urinary tract, which in normal conditions do not contain bacteria, viruses, or other microorganisms. Urinary tract infections are also infections that occupy the second position that most often attacks the body after respiratory infections. The objective of the study was to identify the relationship between catheter placement and the incidence of urinary tract infections at Royal Prima hospital Medan. This is a correlation study (correlation study) on the patients suffering from urinary tract infections. The sampling technique used was a saturated sampling technique. Analysis research data using the Spearmen test. Based on the results of the study, it was found that the majority of catheter installation was in the category of good were 78%, and in the category of not good 22%, and 78% suffered from do not experience urinary tract infections, and 22% infection urinary tract. The results of the study of the Spearmen test showed that p-value = 0.00. It was found that there was a relationship between catheter insertion and the incidence of urinary tract infections in the inpatient room. The local nurses are suggested to improve the aseptic technique of care performed when catheterization is performed so that the incidence of urinary tract infections due to catheter installation can be avoided.


Phimosis is the inability of the penis to potrude from the prepuce either partially or completely and the preputial retractability increases with age. Circumcision is believed by various parties as a form of defense against pathogens that may cause various abnormalities. Smegma is whitish lump that formed from desquamation of preputial epithelial cells. Smegma and bacteria in the prepuce may cause abnormalities such as genital infections, urinary tract infections, and even malignancy. This study aims to determine the presence between phimosis, smegma, and preputial bacteria, and its relationship with inflammatory status of circumcised patient. A cross sectional analytical study for boys who underwent circumcision at Saiful Anwar General Hospital Malang. The data will be analyzed using chi-square and will be calculated for the relative risk. There were 76 patients who underwent circumcision from March 2018 until August 2018. The result was found that the presence of phimosis was significantly associated with the presence of smegma and preputial bacteria (p <0.01) with a risk of 30x and 8x respectively. However, the presence of smegma and preputial bacteria in the prepuce was not significantly associated with the inflammatory status in the prepuce (p = 0.541 & p = 0.084). In conclusion, the presence of phimosis has a significant risk in the formation of smegma and the growth of preputial bacteria.


2008 ◽  
Vol 41 (4) ◽  
pp. 947-951 ◽  
Author(s):  
Harun Peru ◽  
Sevcan Azime Bakkaloglu ◽  
Oguz Soylemezoglu ◽  
Necla Buyan ◽  
Enver Hasanoglu

2018 ◽  
Vol 35 (1) ◽  
Author(s):  
Ayse Sagmak Tartar ◽  
Safak Ozer Balin

Objective: We investigated the geriatric patients diagnosed as urinary tract infection and evaluated the effects of white blood cell (WBC), neutrophil count, platelet, mean platelet volume (MPV), red cell distribution width (RDW), total bilirubin, direct bilirubin, creatine, albumin, erythrocyte sedimentation rate, C-reactive protein, and neutrophil/lymphocyte ratio parameters on estimating the need for bacteremia and intensive care (IC) for the patients with pyelonephritis Methods: Between 2016-2017, a total number of 188 patients aged 65 years and above were retrospectively evaluated at the infectious diseases clinic. Results: The 124 (66%) of the patients were male and 64 (34%) were female. The laboratory values of the patients with pyelonephritis and urosepsis were found to be significantly lower in only RDW bacteremic patients (p=0.047). The laboratory values during the application of third-step IC unit patients, who were treated and discharged, were compared. Albumin was significantly lower, while direct bilirubin, AST and ALT were significantly higher (p<0.05). Conclusions: Patients, whose biochemical parameters have changed, especially during admission or follow-up, should be evaluated carefully in terms of urosepsis, multiple organ failure and IC need. A number of diagnostic tests have been described to predict the need for sepsis and IC. However, many of them cannot be performed in emergency conditions. It is a great advantage that the parameters we use in our work are easily accessible and can be performed in emergency conditions. How to cite this:Tartar AS, Balin SO. Geriatric urinary tract infections: The value of laboratory parameters in estimating the need for bacteremia and Intensive Care Unit. Pak J Med Sci. 2019;35(1):---------. doi: https://doi.org/10.12669/pjms.35.1.97 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2021 ◽  
pp. 148-155
Author(s):  
I. N. Zakharova ◽  
A. N. Tsutsaeva ◽  
S. V. Dolbnya ◽  
V. A. Kuryaninova ◽  
L Ya. Klimov ◽  
...  

Urinary tract infections are a common global problem among physicians of various specialties, including therapists, pediatricians, nephrologists and urologists. Today UTI is one of  the  leading bacterial infections in  both adult and child populations. The main type of therapy and prevention of recurrent UTI is the use of drugs with an antibacterial effect (antibiotics, uroseptics). An urgent problem in modern medical practice is the increasing antibiotic resistance, which requires the development of new approaches to therapy and prevention, including UTI. In recent years, special attention has been paid to the study of vitamin D receptor (VDR) gene polymorphisms as a possible risk factor determining the predisposition to a number of infectious and noninfectious diseases. More than 200 polymorphisms of the VDR gene have been identified, four of which – FokI, BsmI, ApaI, and TaqI – are particularly common. Different VDR alleles can cause small changes in receptor function, which can affect resistance or susceptibility to a particular infection. The review presents data from modern studies demonstrating the relationship between vitamin D supply and development, the frequency of recurrence and the nature of the course of UTI. In one study, vitamin D has been shown to enhance the cathelicidin-mediated antibacterial action of bladder epithelial cells. It also demonstrated the currently known defense mechanisms of vitamin D against urinary tract infections, including its effect on components of the innate immune system.


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