scholarly journals Prevalence, Severity, and Treatment of Recurrent Wheezing During the First Year of Life: A Cross-Sectional Study of 12,405 Latin American Infants

2016 ◽  
Vol 8 (1) ◽  
pp. 22 ◽  
Author(s):  
Javier Mallol ◽  
Dirceu Solé ◽  
Luis Garcia-Marcos ◽  
Nelson Rosario ◽  
Viviana Aguirre ◽  
...  
Author(s):  
Alline Coiado ◽  
Marina Sampaio ◽  
Thais Tellini ◽  
Sônia Marchezi Hadachi ◽  
Lene Garcia Barbosa

  Objetivo: A fenilcetonúria é uma das principais causas de deficiência intelectual, e possui tratamento eficaz, se realizado o diagnóstico e tratamento de forma precoce e um acompanhamento por toda vida. O objetivo deste trabalho é levantar a prevalência de recém-nascidos portadores de fenilcetonúria identificados pela triagem neonatal. Métodos: Estudo transversal no qual foi feito um levantamento de dados sobre triagem neonatal para doença fenilcetonúria realizada num Serviço de Referência de Triagem Neonatal, no período de 1 de janeiro de 2010 a 31 de dezembro de 2015. Resultados: Foi encontrado no período de 5 anos, uma prevalência aproximada de fenilcetonúria de 1: 14.700 e de hiperfenilalaninemia permanente é de 1: 54.500 nascidos vivos. Por meio dos resultados obtidos é possível demonstrar a relevância das recoletas e do seguimento no primeiro ano de vida e de amostras alteradas, assim como a gravidade da população feminina portadora de fenilcetonúria e hiperfenilalaninemia benigna, enfatizando o aumento de possíveis danos cerebrais na fase gestacional. Conclusão: A prevalência de fenilcetonúria e  hiperfenilalaninemia permanente é alta. As recoletas e o seguimento no primeiro ano de vida das amostras alteradas é de extrema importância, principalmente para a população feminina portadora de fenilcetonúria e hiperfenilalaninemia permanente, enfatizando o aumento de possíveis danos cerebrais na fase gestacional. Palavras chave: Fenilcetonúrias, Fenilalanina, Triagem neonatal ABSTRACT: Abstract Phenylketonuria is one of the main causes of intellectual disability, and it has effective treatment, if the diagnosis and treatment is performed early and a lifelong follow-up. The objective of this study is to determine the prevalence of newborns with phenylketonuria identified by newborn screening.  Methods: A cross-sectional study was carried out in which a data collection on newborn screening for phenylketonuria disease was carried out at the Newborn Screening Reference Service from January 1, 2010 to December 31, 2015.  Results: It was found in a 5-year period, an approximate prevalence of phenylketonuria of 1: 14,700 and permanent hyperphenylalaninemia is 1: 54,500 newborns. By means of the obtained results, it is possible to demonstrate the relevance of the recollects and the follow-up in the first year of life and of altered samples, as well as the severity of the female population with phenylketonuria and permanent hyperphenylalaninemia, emphasizing the increase of possible brain damages in the gestational phase. Conclusion: The prevalence of phenylketonuria and permanent hyperphenylalaninemia is high. Recollect and follow-up in the first year of life of the altered samples is extremely important, especially for the female population with phenylketonuria and permanent hyperphenylalaninemia, emphasizing the increase of possible brain damage in the gestational phase.  Keywords: Phenylketonurias. Phenylalanine, Newborn screening    


2018 ◽  
Vol 35 (2) ◽  
pp. 125-131
Author(s):  
Alessandro Leite Cavalcanti ◽  
Thaisy Sarmento Batista de Oliveira ◽  
Thaisy Sarmento Batista de Oliveira ◽  
Kívia Gabriella Gomes Muniz ◽  
Christiane Leite Cavalcanti ◽  
...  

Abstract Drowning is one of the accidents with the greatest impact on health. The objective of this paper was to analyze drowning deaths involving children up to four years of age in Campina Grande, Brazil. A cross-sectional study was developed using secondary data, carried out at the Forensic Medicine Unit. All autopsy reports of children 0-4 years of age, victims of drowning in the period from 2008 to 2011 were evaluated. Data referring to the year of occurrence, victims’ gender and age, time of day, day of week and place of occurrence were collected. Data analysis involved descriptive statistics (frequency distribution). Ninety-three cases of fatal drowning were identified, of which 20 (21.5%) involved children under four years of age. Most victims were male (80%), aged one year (35%). The accidents occurred predominantly during the day (85%), mostly at home (75%). The drowning victims were mostly boys in the first year of life and most cases of drowning occurred at their homes.


2019 ◽  
Vol 29 (4) ◽  
pp. 411-418
Author(s):  
N. V. Shakhova ◽  
E. M. Kamaltynova ◽  
Yu. F. Lobanov ◽  
T. S. Kashinskaya

The objective of the study was to investigate prevalence, clinical and allergological features, and risk factors of bronchial asthma in pre-school children living in urban areas of Altay Krai. Methods. This was a cross-sectional study involving 3,205 children (age, 3 to 6 years) attending pre-school facilities in 5 cities of the Altay Krai. Asthma symptoms were defined using the ISAAC questionnaire. Asthma was diagnosed by clinicians according to GINA. Results. Prevalence of asthma in urban children aged 3 to 6 years was 5.7%; 62.7% of them were previously diagnosed with asthma. Majority of children (59.4%) had mild asthma. Sensitization was detected in 70.3% of children with asthma, most of them were sensitized to dust mites Dermatophagoides pteronyssinus (63.3%), birch pollen (46.6%), and cat epithelium (31.1%). Risk factors of asthma were family history of allergy [odds ratio (OR) 3.2; 95% confidence interval (CI) 2.2–4.6], male gender (OR 2.2, 95% CI 1.5–2.3), preterm birth (OR 2.1, 95% CI 1.3–3.3), smoking parents (OR 1.6, 95% CI 1.2–2.9), (contact with pets during the first year of life (OR 1.4, 95% CI 1.0–2.0). Conclusion. The prevalence of asthma in urban children aged 3 to 6 years living in urban areas of Altay Krai was 5.7%. Most common sensitizers were house dust mites, birch pollen and cat epithelium. The risk factors of pre-school asthma are family history of allergy, male gender, preterm birth, passive smoking and contact with pets during the first year of life. 


2021 ◽  
pp. 140349482098313
Author(s):  
Bjørn E. Holstein ◽  
Sofie Weber Pant ◽  
Janni Ammitzbøll ◽  
Trine Pagh Pedersen

Background: Some studies suggest that favourable socioeconomic circumstances are associated with better parent–child relations but the documentation of such an association is limited and inconsistent. Few studies focused on infancy, few studies relied on objective measurement of parent–infant relations, and few studies included more than one measurement of parent–infant relations in the first year of life. Aims: To report the prevalence of objectively measured problems in parent–infant relations during the first year of life and to examine the association between socioeconomic circumstances and parent–infant relations in an unselected community sample of infants. Methods: Cross-sectional study of a community sample of children from birth to 10 months in 15 municipalities in Denmark, n = 11,765. The exposure variables were population register data about socioeconomic circumstances: (a) parents’ education, (b) family composition, (c) parents’ origin, and (d) parents’ occupational status. The outcome variable was the health visitor’s concerns about the parent–infant relation assessed at four home visits from birth to 10 months after delivery. Results: The proportion of children with concerns about the parent–infant relation was 10.5%, 7.8% at one home visit and 2.8% at two or more home visits. Logistic regression analyses showed that all four indicators of socioeconomic circumstances were associated with concerns about the parent–infant relation in the first year of life. Conclusions: The risk of problematic parent–infant relations were significantly elevated among, children of immigrant parents, and children of parents with shorter education and not in education or work.


2020 ◽  
pp. 004947552098130
Author(s):  
Fabián R Carreño-Almánzar ◽  
Adán Coronado-Galán ◽  
Sonia A Cala-Gómez ◽  
Agustín Vega-Vera

Imported malaria has increased in Colombia since 2015 and has been attributed to migrants coming from Venezuela. We present a series of malaria cases, nested in a retrospective cross-sectional study between 2017 and 2018, aimed at calculating the prevalence of medical diseases among immigrants in a University Hospital in Colombia. Among 154 immigrants admitted for medical causes between 2017 and 2018, 8 were diagnosed with malaria, all due to Plasmodium vivax. Of these, seven had uncomplicated malaria, five had a previous history of malaria, one was critically ill, but none died. We highlight that, similar to other case series of imported malaria, Latin American migrants were young, with similar clinical profiles, having a low proportion of severe cases, and P. vivax was the most frequent cause.


2015 ◽  
Vol 133 (3) ◽  
pp. 235-244
Author(s):  
Arlene de Maria Perez ◽  
Isabela Martins Benseñor

CONTEXT AND OBJECTIVE: The lifestyle of military personnel has been little studied in Brazil. This study evaluated the frequencies of tobacco and alcohol use, sexual behavior and mental health among military students.DESIGN AND SETTING: Cross-sectional study at the Police Academy, in São Paulo.METHODS: Students answered a questionnaire about tobacco use, alcohol consumption, sexual behavior and common mental disorders (CMDs). To analyze associations among the frequencies of smoking and alcohol use, sexually transmitted diseases (STDs) and CMDs during the undergraduate years, we built a multinomial logistic regression model adjusted for age and sex.RESULTS: All 473 students were invited to participate and 430 (90.9%) agreed (10.5% were women). Most were white (76.6%), aged < 30 years, from the upper middle class (78.1%). The frequency of smoking was 6.5%, alcohol consumption 69.3%, STDs 14% and CMDs 15.6%. The use of condoms was low. Fourth-year students presented a lower odds ratio (OR) for STDs than the first-year students: 0.44 (95% confidence interval: 0.22-0.90). Third-year students presented a lower OR for CMDs than the first-year students.CONCLUSION: The frequencies of smoking and CMDs were low, while the frequency of alcohol consumption was similar to that of the Brazilian population. The use of condoms was low, in comparison with previous studies with similar samples. The results suggest that there was a certain degree of protection against CMDs and STDs during the undergraduate years.


2019 ◽  
Vol 7 (2) ◽  
pp. 47-51
Author(s):  
Suci Syahril ◽  
Meldafia Idaman ◽  
Dewi Fransisca

Abstract The use of contraceptive depot medroxyprogesterone acetate (DMPA) increasing lately, but some studies suggest has the side effects of weight gain and contraceptives that have side effect in lipid metabolism. Therefore, about 35% of acceptors of DMPA in the first year to stop the use of DMPA. The objective of this study was to determine the differences of lipid profile between acceptors DMPA with acceptors IUD. This was a obcervational study with cross sectional study. The study wasdone at health center Lubuk Buaya in Padang and at laboratory of Biochemistry Departement in Medical Faculty of Andalas University from Januari until September 2016. The subjects were consisted of two groups, each group had 26 subjects. The examination for LDL and HDL used an enzymatic colorimetric method CHOD-PAP.  Data was analyzed using analysis of t-test with p < 0.05 was considered to be significantly different. HDL levels average in Depo Medroxyprogesterone Acetate was 87,54±14,28 mg/dl and IUD was 75,90±8,67 mg/dl with p < 0.05 (significantly difference). Levels of  LDL means there is no significantly difference between DMPA and IUD acceptors (p> 0.05). This research concluded that there isa significant difference on average levels of HDL in the Depo Medroxyprogesterone Acetate and IUD but levels of LDL there is no significantly difference. The clinically lipid profile in the two groups is in normal range.  


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