scholarly journals Eco-Friendly Synthesis of Silver Nano Particles Using <i>Carica papaya</i> Leaf Extract

2018 ◽  
Vol 08 (01) ◽  
pp. 1-7
Author(s):  
Tenderwealth Clement Jackson ◽  
Timma Oto-Obong Uwah ◽  
Akeem Ayodeji Agboke ◽  
Blessing Edidiong Udo ◽  
Edidiong Michael Udofa
Keyword(s):  
Leaf Extract ◽  
Carica Papaya ◽  
Nano Particles

Phytochemical, hematologic and anti-tumor activity evaluations of Carica papaya leaf extract

2017 ◽  
Vol 3 (3) ◽  
Author(s):  
Hoang Nguyen ◽  
Joseph P Kitzmiller ◽  
Pooja Khungar ◽  
Narendra Dabbade ◽  
Kieu Tho Nguyen ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Carica Papaya ◽  
Anti Tumor Activity

Analgesic Effectivty Of Nanoparticles Chitosan-Ethanol Leaf Extract Papaya (Carica Papaya L.) In White Male Mice (Mus Mucculus)

2017 ◽  
Vol 15 (2) ◽  
pp. 228
Author(s):  
Juliferd Gredi ◽  
Wintari Taurina ◽  
Mohamad Andrie
Keyword(s):  
Leaf Extract ◽  
Carica Papaya ◽  
White Male ◽  
Ethanol Extract ◽  
Test Method ◽  
Ionic Gelation ◽  
Male Mice ◽  
Writhing Test ◽  
Effi Ciency ◽  
Optimal Formula

Papaya leaves has been shown to have efficacy as an analgesic. Analgesic effect caused by the flavonoids in leaves of papaya. To enhance the analgesic effi cacy papaya into dosage formulatio of nanoparticles. The purpose of this research was to create and characterized nanoparticles from ethanol extract of papaya leaves then tested for effectiveness as an analgesic. This study used polymer chitosan and NaTPP to created nanoparticles through ionic gelation method and analgesic activity tested using writhing test method and statistical tested. Optimal formula of nanoparticles were produced at concentration of 0.2% chitosan, Na-TPP extract 0.1% and 4% with a ratio of 6: 1: 1. The nanoparticles was formed a size of 255.4 nm with polidispers index of 0.7, the zeta potential of + 11,1mV, the adsorption effi ciency by 87% and rounded morphology (spherical). Analgesic effectiveness tested by comparison between the groups ethanol extract of papaya and the groups nanoparticles of chitosan-ethanol extract papaya statistically using the T-test Independent. The results of this research indicate that there are statistically signifi cant differences (p <0.05). This results shows that the preparation nanoparticles of chitosan-ethanol extract papaya is more effective as an analgesic than the ethanol extract of papaya leaves.

scholarly journals Effect of Carica papaya (Linn) aqueous leaf extract on pharmacokinetic profile of ciprofloxacin in rabbits

2017 ◽  
Vol 16 (1) ◽  
pp. 127 ◽  
Author(s):  
Grace E. Ukpo ◽  
Mbang A. Owolabi ◽  
Ngozi O.A. Imaga ◽  
Oluwafunke O. Oribayo ◽  
Akpobomen J. Ejiroghene
Keyword(s):  
Leaf Extract ◽  
Carica Papaya ◽  
Pharmacokinetic Profile ◽  
Aqueous Leaf Extract

scholarly journals Synthesis of Silver Nano Particles from Adansonia digitata Leaf Extract and Its Antimicrobial Properties

2020 ◽  
pp. 10-22
Author(s):  
A. O. Akintola ◽  
A. M. Azeez ◽  
B. D. Kehinde ◽  
I. C. Oladipo
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Aspergillus Niger ◽  
Pathogenic Bacteria ◽  
Leaf Extract ◽  
Biomedical Application ◽  
Nano Particles ◽  
Diffusion Method ◽  
Adansonia Digitata ◽  
Inhibition Zones

Silver nano particles (AgNPs) were green synthesized using Adansonia digitata leaf extract. The synthesized silver nano particles were characterized in terms of synthesis, size, shape, morphology and capping functionalities by UV-Visible Spectroscopy, Scanning Electron Microscopy (SEM) and Fourier Transform Infrared Spectroscopy (FTIR). Antimicrobial activity of the synthesized silver nano particles was investigated by well diffusion method. The antibacterial activity of the nano particle was studied against Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeurigunosa, Salmonella typhi and Klebsiella pneumonae while the antifungal activity was studied against Candida albicans, Aspergillus niger, Penicillum notatum and Rhizopus stolomifer. The synthesized AgNPs was active against all the studied microorganisms. Staphylococcus aureus was the most susceptible bacterium (inhibition zones ranging from 12.00 to 28.00 mm, MIC: 30 µl, MBC: 50 µl) while Aspergillus niger was the most susceptible fungi (inhibition zones ranging from 10.00 to 18.00 mm, MIC: 90 µl, MFC: 120 µl. In conclusion the synthesized silver nanoparticles was found to have antimicrobial activity against the pathogenic bacteria and fungi tested and hence has a great potential in biomedical application for the treatment of microbial infections.

scholarly journals The plausible mechanisms of action of Carica papaya on Dengue infection: A comprehensive review

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Zhui Ken Bok ◽  
Manisha Balakrishnan ◽  
Yong Xin Jong ◽  
Yew Rong Kong ◽  
Kooi Yeong Khaw ◽  
...  
Keyword(s):  
At Risk ◽  
Clinical Evaluation ◽  
Leaf Extract ◽  
Carica Papaya ◽  
Dengue Infection ◽  
Mechanisms Of Action ◽  
Treatment Modalities ◽  
Potential Treatment ◽  
Comprehensive Review ◽  
Leaf Juice

Dengue is a serious health endemic with a prediction that 2.5 billion are at risk of acquiring dengue infection and 50 million are infected yearly. Over the years, tremendous effort has been done to develop potential treatment for dengue infection. However, to no avail, most of the treatment modalities have failed in clinical evaluation and trials. With the lack of treatment for dengue infection, home remedies have been widely used as a belief to relieve the symptoms, one of them is the use of papaya leaf juice. This review provides a recent evidences and research that have been attempted to unravel the mechanism of actions of papaya leaf extract to treat dengue infection. Up to date, there are three main mechanisms that have been proposed, which are the anti-thrombocytopenic, immunomodulatory and anti-viral effect of papaya leaf juice extract.

Control of JE vector by organic compounds isolated and green nanoparticles synthesised from leaf extract of Holoptelea integrifolia (Roxb.)

2020 ◽  
Author(s):  
Someshwar Singha ◽  
Goutam Chandra
Keyword(s):  
Spectral Analysis ◽  
Ethyl Acetate ◽  
Larvicidal Activity ◽  
Leaf Extract ◽  
Ethyl Acetate Extract ◽  
Good Alternative ◽  
Nano Particles ◽  
Major Constituent ◽  
Active Principle ◽  
Soxhlet Apparatus

Abstract Background: Japanese encephalitis (JE) is a dreadful disease transmitted by Culex vishnui group of mosquitoes. Control of JE vectors at the larval stage is one of the effective approaches in controlling JE. Methods: Leaves of Holoptelea integrifolia were subjected to petroleum ether, ethyl acetate, acetone and absolute alcohol solvent extraction by Soxhlet apparatus. As the ethyl acetate extract showed best mosquito larvicidal activity against Culex vishnui, it extract was selected and processed further for isolation of active principle through column chromatography and TLC and then characterization of the active principle by FTIR and GC-MS was done. Results: Ethyl acetate extract was found to be the most potent larvicide. In the active fraction of isolated compounds from ethyl acetate extract, N-methyl-1-adamantaneacetamide was the major constituent responsible for larvicidal activity of Culex vishnui. Green nanoparticles were synthesised by treating silver nitrate with leaf extract of H. integrifolia and were examined for larvicidal activity. Nanoparticles were characterised by UV-VIS spectral analysis, XRD study, TEM, SEM and FTIR spectral analysis. Synthesised nanoparticles were 40-50 nm in size and showed good larvicidal activity on Cx. vishnui mosquitoes at 1.25, 2.25, 5, 7.5 and 10 ppm concentrations. Active principle of plant extract and green nanoparticles showed eco-friendly effect on non-target organisms like Chironomus circumdatus, Daphnia sp, Diplonychus anulatum and Tadpole larvae. Conclusion: Thus it can be concluded that active ingredient as well as green synthesized nano particles from H. integrifolia can be a good alternative of presently used chemical insecticides.

Carica Papaya leaf extract as a neuroprotective agent against behavioral and neurotransmitter changes in brain of the rat treated with sodium fluoride in Pre- and Post-Natal periods

2018 ◽  
Vol 14 (55) ◽  
pp. 123
Author(s):  
PratapReddy Karnati ◽  
RajkiranReddy Banala ◽  
KiranKumar Nagapuri ◽  
KhalidPasha Mohd ◽  
MManjula Reddy
Keyword(s):  
Sodium Fluoride ◽  
Leaf Extract ◽  
Carica Papaya ◽  
Neuroprotective Agent

Green silver nano-particles: synthesis using rice leaf extract, characterization, efficacy, and non-target effects

2020 ◽  
Author(s):  
Totan Adak ◽  
Harekrushna Swain ◽  
Sushmita Munda ◽  
Arup Kumar Mukherjee ◽  
Manoj Kumar Yadav ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Nano Particles ◽  
Rice Leaf ◽  
Target Effects
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