scholarly journals Giardia duodenalis infection in dogs affected by primary chronic enteropathy

2020 ◽  
Vol 10 (1) ◽  
pp. 74-79
Author(s):  
Stefania Perrucci ◽  
Federica Berrilli ◽  
Cristina Procopio ◽  
Margherita Montalbano Di Filippo ◽  
Alessio Pierini ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Activity Index ◽  
Giardia Duodenalis ◽  
Clinical Parameters ◽  
Fecal Samples ◽  
Chronic Enteropathy ◽  
Clinical Forms ◽  
Clinical Scoring ◽  
Mild Clinical Presentation ◽  
Age And Sex

Background: Canine primary chronic enteropathy (CE) includes a heterogeneous group of diseases characterized by chronic gastrointestinal signs.Aim: This study evaluated the occurrence of Giardia duodenalis infection in primary CE-affected dogs.Methods: Forty-seven CE-affected dogs of different age and sex were enrolled in the study. For each dog, frequency of defecation, fecal consistency, and eventual fecal abnormalities were evaluated. A clinical scoring index of CE severity (clinical chronic enteropathy activity index) was also assessed, and the type of enteropathy was retrospectively classified. For parasitological analysis, fresh fecal samples collected from each dog were examined by fresh and Lugol stained smears, flotation test, and a rapid immunoassay. Giardia duodenalis genotypes were identified by molecularanalysis. Differences of clinical parameters between G. duodenalis positive and G. duodenalis negative dogs were statistically evaluated.Results: Among the CE canine patients, 16 out of 47 (34%) dogs were found positive for G. duodenalis and assemblages C and D were identified. No statistical differences emerged according to the types of CE between G. duodenalispositive and G. duodenalis-negative dog groups. The clinical index of CE severity was indicative of significant less severe clinical forms in G. duodenalis-positive dogs (p = 0.037).Conclusion: Results here obtained shows how G. duodenalis may be present in primary CE-affected dogs and further investigations are needed to clarify the real significance of mild clinical presentation in G. duodenalis-positive dogs affected by CE. Keywords: Canine, Clinical forms, Genotypes, Giardiasis, Primary chronic enteropathy.

The Diagnostic Assessment of Suspected Pulmonary Embolism on the Acute Medical Take: An Evidence Based Guide

2007 ◽  
Vol 6 (1) ◽  
pp. 20-26
Author(s):  
Alastair Proudfoot ◽  
◽  
Derek Bell ◽  
Keyword(s):  
Risk Factors ◽  
Pulmonary Embolism ◽  
Venous Thromboembolism ◽  
Clinical Presentation ◽  
Diagnostic Assessment ◽  
Evidence Based ◽  
Suspected Pulmonary Embolism ◽  
The Subject ◽  
Adjusted Incidence ◽  
Age And Sex

Pulmonary Embolism is a common cardiopulmonary illness with an age and sex adjusted incidence of around 117 cases per 100 000 person years. The clinical presentation is extremely heterogeneous and non specific. Risk factors for venous thromboembolism are well established. When combined with presenting features and investigations. a multimodality algorithm has led to significant changes in the diagnostic approach of suspected PE. While the best combination of tests for any individual patient remains the subject of controversy this article aims to rationalise the acute physician’s approach to diagnosis and use of available investigations.

Impairment of Antipyrine Metabolism in Urinary Tract Cancer

1983 ◽  
Vol 69 (3) ◽  
pp. 221-222 ◽  
Author(s):  
Maura Ludovici ◽  
Piero Dolara ◽  
Alfiero Costantini ◽  
Guido Barbagli ◽  
Anna Calzolai ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Half Life ◽  
Clinical Parameters ◽  
Tract Cancer ◽  
Patients With Cancer ◽  
Control Subjects ◽  
Antipyrine Metabolism ◽  
Urinary Tract Cancer ◽  
The Mean ◽  
Age And Sex

The metabolism of antipyrine was studied in 13 patients with cancer and bladder papillomas and in 11 control subjects, matched for interfering factors like smoking, diet, age and sex. The mean antipyrine half-life was significantly longer in patients with urinary tract cancer (14.7 ± 1.32 h SE) than in control subjects (11 ± 0.55 h SE) (P < 0.025); other clinical parameters did not vary.

scholarly journals Kingella kingae Osteoarticular Infections Approached through the Prism of the Pediatric Orthopedist

2021 ◽  
Vol 10 (1) ◽  
pp. 25
Author(s):  
Giacomo DeMarco ◽  
Moez Chargui ◽  
Benoit Coulin ◽  
Benoit Borner ◽  
Christina Steiger ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Septic Arthritis ◽  
Surgical Procedures ◽  
Clinical Presentation ◽  
Tendon Sheath ◽  
Skeletal System ◽  
Kingella Kingae ◽  
Osteoarticular Infections ◽  
Acute Hematogenous Osteomyelitis ◽  
Mild Clinical Presentation

Nowadays, Kingella kingae (K. kingae) is considered as the main bacterial cause of osteoarticular infections (OAI) in children aged less than 48 months. Next to classical acute hematogenous osteomyelitis and septic arthritis, invasive K. kingae infections can also give rise to atypical osteoarticular infections, such as cellulitis, pyomyositis, bursitis, or tendon sheath infections. Clinically, K. kingae OAI are usually characterized by a mild clinical presentation and by a modest biologic inflammatory response to infection. Most of the time, children with skeletal system infections due to K. kingae would not require invasive surgical procedures, except maybe for excluding pyogenic germs’ implication. In addition, K. kingae’s OAI respond well even to short antibiotics treatments, and, therefore, the management of these infections requires only short hospitalization, and most of the patients can then be treated safely as outpatients.

scholarly journals Effect of Agro-ecological Zone, Age, and Sex on Prevalence and Intensity of Gastrointestinal Parasites in Donkeys in Maseru District, Lesotho

2021 ◽  
Vol 11 (2) ◽  
pp. 242-248
Author(s):  
Masara Elizabeth Nts’aoana ◽  
Setsumi Mots’oene Molapo ◽  
Paseka Kompi
Keyword(s):  
Parasite Prevalence ◽  
Gastrointestinal Parasites ◽  
Egg Load ◽  
Ecological Zone ◽  
Fecal Samples ◽  
Fecal Egg Count ◽  
One Year ◽  
Coccidian Infection ◽  
Age And Sex

Gastrointestinal parasites are considered to be silent killers of animals. The objective of the current study was to determine the effect of the agro-ecological zone, age, and sex on the parasite prevalence and fecal egg/oocyst count in donkeys residing in Lesotho. A total number of 720 fecal samples were collected rectally from 120 indigenous donkeys that were randomly selected from the highlands, foothills, and lowlands of Maseru district, Lesotho. The fecal samples were collected every two months for one year and examined using the floatation technique. The overall prevalence for nematodes, coccidia, and cestodes in donkeys were 87.78%, 4.31%, and 1.53%, respectively. The highest nematode prevalence and intensity were detected in the donkeys of highlands. The coccidian infection was lower in the lowlands while cestodes infection was more prevalent in the foothills. Donkey’s age had an impact on the nematode fecal egg load but did not affect the prevalence of nematodes in donkeys. Age did not significantly affect the prevalence and fecal egg/oocyst count of cestodes and coccidia. Male donkeys had a higher prevalence and fecal egg count of cestodes. In conclusion, the nematodes were found to be the major gastrointestinal parasites of donkeys in the Maseru district. Therefore, there is a need to design a sustainable strategy aimed at controlling the gastrointestinal parasites in donkeys.

scholarly journals An Autochthonous Outbreak of the SARS-CoV-2 P.1 Variant of Concern in Southern Italy, April 2021

2021 ◽  
Vol 6 (3) ◽  
pp. 151
Author(s):  
Daniela Loconsole ◽  
Anna Sallustio ◽  
Francesca Centrone ◽  
Daniele Casulli ◽  
Maurizio Mario Ferrara ◽  
...  
Keyword(s):  
Neutralizing Antibodies ◽  
Clinical Presentation ◽  
Southern Italy ◽  
Receptor Binding Domain ◽  
Gene Target ◽  
Health Measures ◽  
Molecular Tests ◽  
Laboratory Investigations ◽  
The Impact ◽  
Mild Clinical Presentation

The SARS-CoV-2 P.1 variant of concern (VOC) was first identified in Brazil and is now spreading in European countries. It is characterized by the E484K mutation in the receptor-binding domain, which could contribute to the evasion from neutralizing antibodies. In Italy, this variant was first identified in January 2021. Here, we report an autochthonous outbreak of SARS-CoV-2 P.1 variant infections in southern Italy in subjects who had not travelled to endemic areas or outside the Apulia region. The outbreak involved seven subjects, three of whom had received a COVID-19 vaccine (one had received two doses and two had received one dose). Four patients had a mild clinical presentation. Laboratory investigations of nasopharyngeal swabs revealed that all strains were S-gene target failure-negative and molecular tests revealed they were the P.1 variant. Whole-genome sequencing confirmed that five subjects were infected with closely related strains classified as the P.1 lineage. The circulation of VOCs highlights the importance of strictly monitoring the spread of SARS-CoV-2 variants through genomic surveillance and of investigating local outbreaks. Furthermore, public health measures including social distancing, screening, and quarantine for travelers are key tools to slow down the viral transmission and to contain and mitigate the impact of VOC diffusion, and rapid scaling-up of vaccination is crucial to avoid a possible new epidemic wave.

scholarly journals Mild Clinical Presentation of Acute Fatty Liver in the Second Trimester of Pregnancy

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Alaeddine Yassin ◽  
Walid Denguezli ◽  
Anissa Fessi ◽  
Leila Njim ◽  
Raja Falah ◽  
...  
Keyword(s):  
Fatty Liver ◽  
Clinical Presentation ◽  
Second Trimester ◽  
Acute Fatty Liver ◽  
Mild Clinical Presentation

We report a case of 29 years old woman who was diagnosed with acute fatty liver of pregnancy at 23 weeks of gestation with unusual evolution (pregnancy prolonged until 36 weeks of gestation) to draw attention on the possibility of occurrence of this pathology in the second trimester of pregnancy even with a milder clinical presentation and course.

scholarly journals Giardia duodenalis: genotypic comparison between a human and a canine isolates

2011 ◽  
Vol 44 (4) ◽  
pp. 508-510 ◽  
Author(s):  
Karina Braga Gomes ◽  
Ana Paula Fernandes ◽  
Aline Menezes ◽  
Ronaldo Amorim Júnior ◽  
Edward Félix Silva ◽  
...  
Keyword(s):  
Giardia Duodenalis ◽  
Zoonotic Disease ◽  
Specific Region ◽  
Genetic Identity ◽  
Fecal Samples ◽  
Belo Horizonte

INTRODUCTION: Evidence suggests that giardiasis is a zoonotic disease. The present work aimed to evaluate the genetic identity of Giardia duodenalis isolated from human and dog fecal samples from Belo Horizonte. METHODS: Human and dog fecal samples were cultured for isolation of G. duodenalis. To determine the genotype of the isolates, primers that amplify a specific region in rRNA of the protozoan were used. RESULTS: Two G. duodenalis isolates were obtained, which belong to the subgroup A genotype. CONCLUSIONS: These findings suggest that the transmission of giardiasis follows a zoonotic pattern.

scholarly journals A report on a case of Giardia duodenalis

2017 ◽  
Vol 7 (2) ◽  
pp. 1218-1220
Author(s):  
Sujata Pudasaini ◽  
Rakesh Pathak ◽  
Satyam Upadhyaya ◽  
Anna Sharma
Keyword(s):  
Weight Loss ◽  
Developing Countries ◽  
Giardia Lamblia ◽  
Clinical Presentation ◽  
Giardia Duodenalis ◽  
Duodenal Biopsy ◽  
Histopathological Diagnosis ◽  
Intestinal Protozoan ◽  
Worldwide Distribution ◽  
Common Causes

ABSTRACTGiardia is caused by protozoa, Giardia lamblia. It is one of the most common causes of water born or food born diarrhea and it has a worldwide distribution. The prevalence is approximately 20-30% in developing countries. Giardia duodenalis is the most commonly reported intestinal protozoan in humans mainly affecting children. The infection is usually associated with malabsorption, weight loss and growth retardation.We report a case of four years old boy who presented with diarrhea and malabsorption for last 2 years. Its clinical presentation and histopathological diagnosis on duodenal biopsy is discussed.

PCR-RFLP method to detect zoonotic and host-specific Giardia duodenalis assemblages in dog fecal samples

2016 ◽  
Vol 115 (5) ◽  
pp. 2045-2050 ◽  
Author(s):  
Liping Tan ◽  
Sheng Wu ◽  
Auwalu Yusuf Abdullahi ◽  
Xinggang Yu ◽  
Wei Hu ◽  
...  
Keyword(s):  
Giardia Duodenalis ◽  
Fecal Samples ◽  
Pcr Rflp

scholarly journals Correlation between extraintestinal manifestations and clinical parameters with the histologic activity index in patients with inflammatory bowel diseases

2013 ◽  
Vol 70 (10) ◽  
pp. 947-952
Author(s):  
Milos Stulic ◽  
Djordje Culafic ◽  
Dragana Mijac ◽  
Goran Jankovic ◽  
Ivana Jovicic ◽  
...  
Keyword(s):  
Disease Activity ◽  
Clinical Laboratory ◽  
Inflammatory Diseases ◽  
Activity Index ◽  
Clinical Parameters ◽  
Extraintestinal Manifestations ◽  
Cross Sectional ◽  
Group I ◽  
Significant Difference ◽  
Group Ii

Bacground/Aim. Crohn's disease (CD) and ulcerative colitis (UC) are chronic, idiopathic, inflammatory diseases of the digestive tract. The aim of this study was to determine a possible correlation between the clinical parameters of the disease activity degree and the presence of extraintestinal manifestations with disease activity histopathological degree, in patients presented with CD and UC. Methods. This cross-sectional study included 134 patients (67 with CD and UC, respectively) treated at the Clinic of Gastroenterology, Clinical Center of Serbia, Belgrade. After clinical, laboratory, endoscopic, histopathologic and radiologic diagnostics, the patients were divided into two groups according to their histopathological activity. The group I comprised 79 patients whose values of five-grade histopathological activity were less than 5 (45 with CD and 34 with UC), while the group II consisted of 55 patients with the values higher than 5 (22 with CD and 33 with UC). The CD activity index (CDAI) and Truelove and Witts' scale of UC were used for clinical evaluation of the disease activity. Results. CD extraintestinal manifestations were present in 28.9% and 63.6% of the patients in the groups I and II, respectively (p < 0.05). Comparison of the mean CDAI values found a significant difference between these two patients groups (the group I: 190.0 ? 83.0, the group II: 263.4 ? 97.6; p < 0.05). No correlation of extraintestinal manifestations of the disease, Truelove and Witts' scale and histological activity was found in UC patients (p > 0.05). Conclusion. In the patients presented with CD, the extraintestinal manifestations with higher CDAI suggested a higher degree of histopathological activity. On the contrary, in the UC patients, Truelove and Witts' scale and extraintestinal manifestations were not valid predictors of the disease histopathological activity.

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