Influence on Mycobacterium tuberculosis infection on the serum levels of antioxidant vitamins and trace elements

2008 ◽  
Vol 15 (2) ◽  
Author(s):  
OG Arinola ◽  
MO Akiibinu
Keyword(s):  
Trace Elements ◽  
Mycobacterium Tuberculosis ◽  
Serum Levels ◽  
Antioxidant Vitamins

scholarly journals Biochemical changes in some trace elements, antioxidant vitamins and their therapeutic importance in prostate cancer patients

2014 ◽  
Vol 6 (1) ◽  
pp. 95-97 ◽  
Author(s):  
Bridget Obiageli Onyema-iloh ◽  
Samuel C Meludu ◽  
Emmanuel Iloh ◽  
Johnkennedy Nnodim ◽  
Onyema Onyegbule ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Trace Elements ◽  
Vitamin A ◽  
Cancer Patients ◽  
High Performance ◽  
Serum Levels ◽  
Serum Copper ◽  
Antioxidant Vitamins ◽  
Copper Level ◽  
Antioxidant Vitamin

Aim: This study was conducted to evaluate the serum levels of some trace-elements (zinc, copper and selenium) and antioxidant vitamins (vitamin A, C and E) in prostate cancer patients. Method: A total of 50 prostate cancer patients aged 50-70 years with PSA > 4.0 ng/dl were recruited for the study while 50 apparently healthy individual were used as control subjects. Zinc, copper and selenium were determined using atomic absorption spectrophotometer while vitamin A, C and E were determined using high performance liquid chromatography. Result: The result showed that the mean levels of Se (0.77±0.26), Zn(147.75±42.05) were significantly lower (p <0.05) when compared with the control (1.47±0.13) and (168.78±59.80) respectively. The serum copper level (187. 76±66.05) was significantly higher (p<0.05) when compared with control (126.40±31.24).The antioxidant vitamin A (0.42±0.19), vitamin C (3.62±1.81) and vitamin E (0.39±0.13) were Significantly lower p(<0.05) when compared with the control (0.68±0.32)(12.16±4.07) and (1.40±0.16) respectively. Concusion: The decreased trace elements and antioxidant vitamins may be associated with high free radicals generated due to oxidative stress in prostate cancer patient. DOI: http://dx.doi.org/10.3126/ajms.v6i1.10799 Asian Journal of Medical Sciences Vol.6(1) 2015 95-97

scholarly journals Cytokine Biosignature of Active and Latent Mycobacterium Tuberculosis Infection in Children

Pathogens ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 517
Author(s):  
Magdalena Druszczynska ◽  
Michal Seweryn ◽  
Sebastian Wawrocki ◽  
Magdalena Kowalewska-Pietrzak ◽  
Anna Pankowska ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Inflammatory Mediators ◽  
Latent Tuberculosis ◽  
Serum Levels ◽  
Diagnostic Tools ◽  
Mycobacterium Tuberculosis Infection ◽  
Only Children ◽  
Latent Tb ◽  
Ifn Γ ◽  
Multiplex Bead

None of the currently used diagnostic tools are efficient enough in diagnosing Mycobacterium tuberculosis (M.tb) infection in children. The study was aimed to identify cytokine biosignatures characterizing active and latent tuberculosis (TB) in children. Using a multiplex bead-based technology, we analyzed the levels of 53 Th17-related cytokines and inflammatory mediators in sera from 216 BCG-vaccinated children diagnosed with active TB (TB) or latent TB (LTBI) as well as uninfected controls (HC). Children with active TB, compared to HC children, showed reduced serum levels of IL-17A, MMP-2, OPN, PTX-3, and markedly elevated concentrations of APRIL/TNFSF13. IL-21, sCD40L, MMP-2, and IL-8 were significantly differentially expressed in the comparisons between groups: (1) HC versus TB and LTBI (jointly), and (2) TB versus LTBI. The panel consisting of APRIL/TNFSF13, sCD30/TNFRSF8, IFN-α2, IFN-γ, IL-2, sIL-6Rα, IL-8, IL-11, IL-29/IFN-λ1, LIGHT/TNFSF14, MMP-1, MMP-2, MMP-3, osteocalcin, osteopontin, TSLP, and TWEAK/TNFSF12 possessed a discriminatory potential for the differentiation between TB and LTBI children. Serum-based host biosignatures carry the potential to aid the diagnosis of childhood M.tb infections. The proposed panels of markers allow distinguishing not only children infected with M.tb from uninfected individuals but also children with active TB from those with latent TB.

Expression of lymphocyte subpopulations, cytokine serum levels and blood and urine trace elements in nickel sensitised women

Life Sciences ◽  
1998 ◽  
Vol 63 (16) ◽  
pp. 1417-1422 ◽  
Author(s):  
P. Boscolo ◽  
M. Di Gioacchino ◽  
P. Conti ◽  
R.C. Barbacane ◽  
M. Andreassi ◽  
...  
Keyword(s):  
Trace Elements ◽  
Serum Levels ◽  
Lymphocyte Subpopulations

scholarly journals Trace elements in patients with aortic valve sclerosis

2021 ◽  
Vol 15 ◽  
pp. 175394472098598
Author(s):  
Hataw Al-Taesh ◽  
Abuzer Çelekli ◽  
Murat Sucu ◽  
Seyithan Taysi
Keyword(s):  
Trace Elements ◽  
Aortic Valve ◽  
Inductively Coupled Plasma ◽  
Healthy Subjects ◽  
Serum Zinc ◽  
Serum Levels ◽  
Control Group ◽  
Aortic Valve Sclerosis ◽  
Inductively Coupled ◽  
Significant Difference

Background: Aortic valve sclerosis (AVSc) is defined as the thickening and calcification of aortic valve cusps, in the absence of obstruction of ventricular outflow. AVSc is linked with a clear imbalance in some trace elements. Aims: The objective of this study was to investigate the relationship between AVSc and serum levels of iron (Fe), zinc (Zn), selenium (Se), and copper (Cu). Additionally, this research aimed to explore the clinical significance of human serum zinc, selenium, copper, and iron concentrations as a potential new biomarker for AVSc patients and to clarify the pathophysiological role in individuals at risk of developing AVSc. Patients and methods: The study included 40 subjects with AVSc (25% male and 75% female) who were compared with a healthy control group with the same gender ratio. AVSc was based on comprehensive echocardiographic assessments. Blood samples were taken and Zn and Cu concentrations were determined through the use of atomic absorption spectroscopy. Se was measured using an inductively coupled plasma mass spectrometry device and Fe was measured using a Beckman Coulter instrument. Results: There was a significant difference in the prevalence of diabetes, blood pressure levels, and body mass index between the patients and the healthy subjects ( p < 0.05). The differences between the serum Fe, Se, and Cu levels of the AVSc patients and the healthy subjects ( p > 0.05) were recorded. The serum Zn of AVSc patients when compared was significantly lower compared with that of the control group ( p < 0.01). Conclusion: Patients with AVSc had an imbalance in some of the trace elements in their blood. The patient group’s valves had higher serum Cu levels and lower serum Se, Zn, and Fe concentrations compared with the healthy group’s valves. In the valve patients as compared, AVSc had a high prevalence of obesity, hypertension, and diabetes.

scholarly journals Antioxidant vitamins in the context of nonalcoholic fatty liver disease in obese children and adolescents

2013 ◽  
Vol 31 (4) ◽  
pp. 523-530 ◽  
Author(s):  
Fábio da Veiga Ued ◽  
Virgínia Resende S. Weffort
Keyword(s):  
Liver Disease ◽  
Dietary Intake ◽  
Fatty Liver ◽  
Children And Adolescents ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
Serum Levels ◽  
Antioxidant Vitamins ◽  
Obese Children ◽  
Nonalcoholic Fatty Liver

OBJECTIVE: To review the literature on the importance of antioxidant vitamins, analyzed in the context of dietary intake, its plasma levels, and its current use as a supplementation treatment in obese children and adolescents with nonalcoholic fatty liver disease. DATA SOURCES: The articles were identified in Lilacs, Ibecs, SciELO, PubMed/Medline, and Scopus databases. To conduct the survey, the "fatty liver" descriptor was associated to the following words: "children", "antioxidants" and "vitamins". The search was limited to articles written in Portuguese, Spanish and English, with publication date until December, 2012. DATA SYNTHESIS: Six studies were selected. The survey revealed a low dietary intake and low antioxidant vitamins serum levels in this population. The changes in lifestyle, with adequate dietary intake of vitamins, and the increase in physical activity were associated with a significant improvement in liver histology and in laboratory tests. Vitamin supplementation also improved the disease progression markers, as the alanine aminotransferase serum levels and the histological characteristics of lobular inflammation and hepatocellular damage. However, these improvements were not statistically significant in all studies. CONCLUSIONS: There is insufficient evidence to recommend or to refute antioxidant supplementation in patients with simple steatosis or steatohepatitis. The changes in lifestyle seem to be, at the present time, the more advisable therapy.

scholarly journals Serum levels of trace elements in children born after assisted reproductive technology

2019 ◽  
Vol 495 ◽  
pp. 664-669 ◽  
Author(s):  
Xin-ru Xia ◽  
Shi-Wen Jiang ◽  
Yuan Zhang ◽  
You-fang Hu ◽  
Hong-gang Yi ◽  
...  
Keyword(s):  
Trace Elements ◽  
Assisted Reproductive Technology ◽  
Serum Levels ◽  
Reproductive Technology

Serum levels of antioxidant vitamins and mineral elements of human immunodeficiency virus positive subjects in Sokoto, Nigeria

2010 ◽  
Vol 9 (4) ◽  
pp. 235 ◽  
Author(s):  
Yusuf Saidu ◽  
Mansur Lawal ◽  
ChibuezeH Njoku ◽  
LawalS Bilbis ◽  
DorcasB Idowu
Keyword(s):  
Human Immunodeficiency Virus ◽  
Serum Levels ◽  
Mineral Elements ◽  
Antioxidant Vitamins ◽  
Immunodeficiency Virus

scholarly journals Serum levels of Cadmium, Calcium, Lead and Iron in Schizophrenic Patients

1970 ◽  
Vol 5 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Pinky Karim ◽  
Md. Iqbal Hossain ◽  
AFM Nazmus Sadat ◽  
Zabun Nahar ◽  
Md. Khalid Hossain ◽  
...  
Keyword(s):  
Trace Elements ◽  
Serum Concentration ◽  
Prognostic Significance ◽  
Serum Levels ◽  
Schizophrenic Disorder ◽  
Flame Atomic Absorption Spectroscopy ◽  
Flame Atomic Absorption ◽  
Schizophrenic Patients ◽  
Calcium Lead ◽  
Exact Correlation

The serum concentration of cadmium (Cd), lead (Pb), calcium (Ca) and iron (Fe) in 30 schizophrenic patients and 30 normal healthy subjects were analyzed by flame atomic absorption spectroscopy. The concentrations of Cd, Pb and Ca in schizophrenic disorder patients was not increased significantly (P > 0.05) compared to that of the cohort controls. But the concentration of Fe in schizophrenic patients was significantly different from that of the cohort control (p < 0.000). The change in serum concentration of different trace elements may have some prognostic significance for the diagnosis of schizophrenic disorder. However further work is suggested to examine the exact correlation between trace elements level and the degree of disorder in schizophrenic patients. Key words: Schizophrenic patients, trace elements, clinical significance Dhaka Univ. J. Pharm. Sci. Vol.5(1-2) 2006 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website

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