scholarly journals Alpha-Glucosidase Inhibitory and Antioxidant Activity of Solvent Extracts and Fractions of Typha domingensis (Typhaceae) Fruit

2015 ◽  
Vol 14 (11) ◽  
pp. 1983 ◽  
Author(s):  
Tsun-Thai Chai ◽  
Mei-Jee Chiam ◽  
Chi-Hou Lau ◽  
Nor Ismaliza Mohd Ismail ◽  
Hean-Chooi Ong ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Typha Domingensis ◽  
Alpha Glucosidase

scholarly journals Phytotherapy in the Management of Diabetes: A Review

2017 ◽  
Author(s):  
Paolo Governa ◽  
Giulia Baini ◽  
Vittoria Borgonetti ◽  
Giulia Cettolin ◽  
Daniela Giachetti ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Medicinal Plants ◽  
Clinical Investigation ◽  
Clinical Effectiveness ◽  
Mechanisms Of Action ◽  
Evidence Based ◽  
Medicinal Products ◽  
Key Points ◽  
Treatment Of Diabetes ◽  
Alpha Glucosidase

Phytotherapy has long been a source of medicinal products and many attempts to use herbal medicine for the treatment of diabetes has been done over the years. Several medicinal plants and their preparations demonstrated to act in key points of glucidic metabolism. The most common mechanisms of action found include the inhibition of α-glucosidase and of AGE formation, the increase of GLUT-4 and PPARs expression and the antioxidant activity. Despite the large amount of literature available, the actual clinical effectiveness of medicinal plants in controlling diabetes related symptoms is still controversial and there is a crucial need for stronger evidence-based data. In this review, an overview of the medicinal plants, which use in the management of diabetes is supported by authoritative monograph, is provided. References to some species which are currently under growing clinical investigation are also reported.

scholarly journals Kandungan Fitokimia dan Bioaktivitas Ekstrak Metanol Biji Palem Putri (Veitchia merillii)

2016 ◽  
Vol 2 (1) ◽  
pp. 63-70
Author(s):  
Adawiah Adawiah
Keyword(s):  
Antioxidant Activity ◽  
Secondary Metabolites ◽  
Radical Scavenging ◽  
Positive Control ◽  
Antidiabetic Activity ◽  
Phytochemical Content ◽  
Sample Extract ◽  
Ic50 Value ◽  
Ic50 Values ◽  
Alpha Glucosidase

Palem putri (Veitchia merillii) is a kinds of Araceae plant which has been used by the community in cure myopic eyes and for woman who have pregnant. However, research on the content of secondary metabolites and bioactivity of palm putri has never been done. This study aims to determine the phytochemical content, total polyphenols and flavonoids and bioactivity include antioxidant activity DPPH free radical scavenging, antidiabetic method alpha-glucosidase enzyme inhibition and toxicity of the methods Bhrine Shrimp Lethal Test (BSLT). Palem putri contains secondary metabolites, alkaloids, flavonoids, terpenoids, polyphenols, phenolic hydroquinone and saponins. The methanol extract of palm putri seed has a total polyphenol content and total flavonoids respectively 642.8 mg gallic acid / gram sample extract and quercetin 543.3 mg / gram sample extract, has a very strong antioxidant activity with IC50 value of  0.82 ppm, the level of toxicity is very toxic with LC50 values ​​of 11.535 ppm. As well as having antidiabetic activity using the enzyme alpha-glucosidase inhibition with IC50 values ​​of 1.97 ppm is even higher than the activity of the compound quercetin as a positive control.  Keywords: Palem putri, bioactivity, antioxidant, antidiabetic, toxicity Palem putri (Veitchia merillii) is a kinds of Araceae plant which has been used by the community in cure myopic eyes and for woman who have pregnant. However, research on the content of secondary metabolites and bioactivity of palm putri has never been done. This study aims to determine the phytochemical content, total polyphenols and flavonoids and bioactivity include antioxidant activity DPPH free radical scavenging, antidiabetic method alpha-glucosidase enzyme inhibition and toxicity of the methods Bhrine Shrimp Lethal Test (BSLT). Palem putri contains secondary metabolites, alkaloids, flavonoids, terpenoids, polyphenols, phenolic hydroquinone and saponins. The methanol extract of palm putri seed has a total polyphenol content and total flavonoids respectively 642.8 mg gallic acid / gram sample extract and quercetin 543.3 mg / gram sample extract, has a very strong antioxidant activity with IC50 value of  0.82 ppm, the level of toxicity is very toxic with LC50 values ​​of 11.535 ppm. As well as having antidiabetic activity using the enzyme alpha-glucosidase inhibition with IC50 values ​​of 1.97 ppm is even higher than the activity of the compound quercetin as a positive control.   Keywords: Palem putri, bioactivity, antioxidant, antidiabetic, toxicity DOI: http://dx.doi.org/10.15408/jkv.v2i1.3076

scholarly journals Phytochemical Content, Antioxidant, Alpha-Glucosidase Inhibitory and Antibacterial Activities of Spineless Cactus Pear Cultivars

Plants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1312
Author(s):  
Mologadi B. Mabotja ◽  
Sonja L. Venter ◽  
Christian P. Du Plooy ◽  
Tukayi Kudanga ◽  
Stephen O. Amoo
Keyword(s):  
Antioxidant Activity ◽  
Antibacterial Activity ◽  
Radical Scavenging ◽  
Antibacterial Activities ◽  
Total Phenolic ◽  
Cactus Pear ◽  
Phytochemical Content ◽  
E Coli ◽  
Alpha Glucosidase ◽  
Phenolic And Flavonoid

Variation in cultivars can influence plant biological activities. This study aimed to identify superior cultivars while determining the variability in the phytochemical content, antioxidant, alpha-glucosidase inhibitory and antibacterial activities of cladode extracts from selected spineless Burbank cactus pear (Opuntia ficus-indica and Opuntia robusta) cultivars. Total phenolic and flavonoid contents were determined using the Folin-Ciocalteu and aluminum chloride spectrophotometric methods, respectively. Antioxidant activity was investigated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging and β-carotene linoleic acid assays. Alpha-glucosidase inhibition was determined using a spectrophotometric method and antibacterial activity using a non-polar (petroleum ether) and polar (50% methanol) extracts against two Gram-positive and two Gram-negative bacteria. Significant variation in phytochemical content, antioxidant, antidiabetic and antibacterial activities was observed amongst the cultivars. Alpha-glucosidase inhibitory activity varied widely with IC50 values ranging from 0.06 to 1.85 mg/mL. Radical scavenging activity of Polypoly cultivar was about seven fold higher than that recorded in other cultivars with low activity. Turpin and Berg x Mexican cultivars had the highest total phenolic and flavonoid contents, whilst the non-polar extract of Turpin also exhibited higher antibacterial activity against Bacillus subtilis and Escherichia coli. Sicilian Indian Fig was amongst the cultivars with a higher antioxidant activity, whilst also showing a strong inhibition against B. subtilis and E. coli. Polypoly cultivar demonstrated strong antioxidant and antidiabetic activities while its polar extract showed the highest total antibacterial activity against B. subtilis. The cultivar Malta was superior in terms of its antibacterial potency and efficacy against B. subtilis, Staphylococcus aureus and E. coli. The potential of using spineless cactus pear cladodes as a functional food with antioxidant, antidiabetic and antibacterial properties against pathogenic food spoilage bacteria in place of synthetic compounds was established. The significance of cultivar selection to increase this potential was highlighted.

Antioxidant Activity and Alpha-Glucosidase Inhibitory Activity of Stings of Gleditsia sinensis Extracts

2011 ◽  
Vol 21 (1) ◽  
pp. 62-67 ◽  
Author(s):  
Jeung-Min Lee ◽  
Jae-Hee Park ◽  
Won-Mi Chu ◽  
Yi-Mook Yoon ◽  
Eun-Ju Park ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Inhibitory Activity ◽  
Gleditsia Sinensis ◽  
Alpha Glucosidase

Insulin Secretagogue, Alpha-glucosidase and Antioxidant Activity of Some Selected Spices in Streptozotocin-induced Diabetic Rats

2011 ◽  
Vol 66 (1) ◽  
pp. 85-90 ◽  
Author(s):  
Swapnil Balasaheb Patil ◽  
Varsha Adhikrao Ghadyale ◽  
Shreehari Subhash Taklikar ◽  
Chaitanya Ramesh Kulkarni ◽  
Akalpita Umesh Arvindekar
Keyword(s):  
Antioxidant Activity ◽  
Diabetic Rats ◽  
Insulin Secretagogue ◽  
Alpha Glucosidase

scholarly journals Nutrient Content, Phytonutrient Composition, Alpha Amylase, Alpha Glucosidase Inhibition Activity and Antioxidant Activity of the Stoechospermum Marginatum Collected in Pre Monsoon Season

2017 ◽  
Vol 5 (3) ◽  
pp. 275
Author(s):  
Reka Palanivel ◽  
Thahira Banu Azeez ◽  
Seethalakshmi Muthaya
Keyword(s):  
Antioxidant Activity ◽  
Physicochemical Properties ◽  
Brown Algae ◽  
Phenolic Content ◽  
Monsoon Season ◽  
Nutrient Content ◽  
Alpha Amylase ◽  
Total Phenolic ◽  
Inhibition Activity ◽  
Alpha Glucosidase

The objective of this study was to investigate the nutrient content, phytonutrient composition, physicochemical properties, alpha amylase and alpha glucosidase inhibition activity and antioxidant activity of the brown algae Stoechospermum marginatum collected from Gulf of Mannar, Tamil Nadu, India in pre monsoon season (June- September, 2015). Six and eight hours of ethanol and aqueous extract of Stoechospermum marginatum were used for phytonutrient screening, alpha amylase, alpha glucosidase inhibition activity and antioxidant activity. From the results of the study it is understood that Stoechospermum marginatum contain a high amount of carbohydrate, protein, crude fiber and phytonutrients like tannin, flavonoid, saponin, alkaloid, terpenoids, steroid and total phenolic content. The physicochemical properties namely Water absorption and Swelling power were very promising. Alpha amylase and alpha glucosidase inhibition activity was recorded to be high in both aqueous and ethanol extracts of eight hour extraction than in extracts taken from six hours extraction. Antioxidant activity was detected using DPPH, FRAP, beta carotene scavenging and H2O2 assay and found to have a high radical scavenging activity. Stoechospermum marginatum possess a valuable amount of total phenolic content and other phytonutrients and physicochemical properties, it may the reason for the potential inhibition of alpha amylase, alpha glucosidase and antioxidant activity. It is concluded from the study that the brown algae may be incorporated into foods to enhance their nutritional and therapeutic value.

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