scholarly journals TO EVALUATE THE EFFICACY OF MADHAVIMOOLA (HIPTAGE BENGHALANSIS ROOT) AS STRI KATIBHAGA KSHEENAKA YOGA – A PILOT STUDY

2020 ◽  
Vol 8 (10) ◽  
pp. 4593-4599
Author(s):  
Aabha Sharma
Keyword(s):  
Clinical Trial ◽  
Pilot Study ◽  
Waist Circumference ◽  
Randomised Clinical Trial ◽  
The Body ◽  
Single Group ◽  
Hip Circumference ◽  
Waist Hip Ratio ◽  
Significant Difference ◽  
Butter Milk

Background: Obesity (Medo Roga) is a Kapha Pradhana, Atibrimhana Janya Vyadhi, where Shleshma Dosha seated in (Medodhatu). According to Ayurvedic perspective, it is clear that Kledaka Kapha, Sama-na-Vyana Vata, Pachaka Pitta, Medo Dhatu and Medodhatwagni are involved in the pathogenesis of Medo Roga1. The excessively increased Asthayi Medo Dhatu is Ama in nature, due to which it is retained in the body for a longer period resulting in further complications. For this Langhana treatment is mainly high-lighted in Grantha2. The challenging nature (relapsing) of the disease makes it difficult to be treated. Aim and Objective: The aim of the present study was to evaluate the efficacy of Madhavimoola in the reduc-tion of female waist circumference. Settings and Design: Single arm, Open Randomised clinical trial. Ma-terials and Methods: Here, Madhavimoola is selected for the study to evaluate its efficacy over female’s waist circumference, on 30 patients for 45 days on empty stomach with (Nisneha Takra) fat-free butter-milk, early in the morning, in single group. Results: The results were highly significant (p<0.001) in the objective criteria  Waist Circumference, Hip Circumference, Waist-Hip Ratio, Weight, except than in BMI = 0.161. In subjective criteria Abdomen-Breast movements (Udara-Stana Chalatva) and symptom of weakness (Daurbalya) showed significant difference (p=0.016). Conclusion: The study showed good re-sults in reducing waist circumference (Katibhaga) in female subjects.

scholarly journals TO PERFORM VARIOUS ANTHROPOMETRIC MEASUREMENTS IN CLINICAL CASES OF OBESITY

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Amit Saxena ◽  
Atishay Jain
Keyword(s):  
Waist Circumference ◽  
Anthropometric Measurements ◽  
Hip Circumference ◽  
Waist Hip Ratio ◽  
Co Morbidity ◽  
Significant Difference ◽  
The Mean ◽  
Presence And Absence ◽  
The Difference ◽  
Medical Wards

Method: This Prospective cross–sectional study was carried out in the Department of Medicine; we studied 211 consecutive patients of obesity presenting in general medicine OPD and general medical wards having associated co-morbidity. All patients or their relatives provided valid informed written consent for participation. Result: The above table shows the mean comparison of FBS, BMI, waist hip ratio, waist circumference, hip circumference, weight and age between presence and absence of CAD. The difference was found to be statistically significant for hip circumference (P < 0.05) with a larger hip circumference in CAD present patients in comparison to the CAD absent patients. While the difference in all the other parameters were found to be statistically not significant (P>0.05), showing that all the parameters were comparable. Conclusion: Conclusion derived from the study conducted on 211 patients of diabetes mellitus type II and overweight W.C., WHR and BMI are important, simple, cost effective, anthropometric measurements. Hence we recommended that all patients of obesity visiting Medical OPD and admitted in medical wards should not only be assessed for associated co-morbidities but for time tested anthropometric measurements. The above table shows the mean comparison of FBS, BMI, waist hip ratio, waist circumference, hip circumference, weight and age between presence and absence of CVA. Statistically significant difference was seen in the waist circumference and WHR higher in patients with CVA in comparison to patients without CVA (P < 0.05). No statistically significant difference was seen in any of the parameters (P>0.05) between absence and presence of CVA, showing that all the parameters were comparable. Keywords: Aanthropometric, Proforma, Clinical & Obesity.

scholarly journals The Effect of L-Carnitine Supplementation on Weight and Body Composition in Women with Polycystic Ovary Syndrome: A Double-Blind Randomized Clinical Trial

2020 ◽  
Author(s):  
Fatemeh Pakravanfar ◽  
Akram Ghadiri-Anari ◽  
Azadeh Nadjarzadeh ◽  
Hossein Fallahzadeh ◽  
Mahdieh Hosseinzadeh
Keyword(s):  
Clinical Trial ◽  
Body Mass Index ◽  
Body Composition ◽  
Waist Circumference ◽  
Randomized Clinical Trial ◽  
Body Mass ◽  
Fat Mass ◽  
Hip Circumference ◽  
Double Blind ◽  
Significant Difference

Background: Polycystic ovarian syndrome (PCOS), one of the most common causes of endocrine disorders with irregular menstruation, is accompanied by an increase in androgen and polycystic ovarian. The aim of this study was to evaluate the effect of weight loss regimen with and without supplementation. L-carnitine affects lipid profile, insulin, and hormone resistance indices. Methods: This double-blind randomized clinical trial was conducted over women within the age range of 18 to 45 years, who referred to Yazd Diabetes Center in 2019. The participants were divided into the experimental and control groups. The intervention group received 1000 mg L-carnitine (LG = 28) and the placebo group (PG = 28) received the placebo daily. All people followed a low celery diet for 12 weeks. Anthropometric indices and body composition (weight, body mass index, waist circumference, hip circumference, fat mass, and free fat mass) were measured prior to and after the intervention. Data analysis was performed using SPSS software version 22. The independent sample t-test was used to compare the mean changes between the LG and PG. Results: At the end of the study period, patients treated with L-carnitine showed a significant decrease in waist circumference compared to the PG (change: -1 ± 3.15, P = 0.001) and no significant difference was observed between the two groups in terms of other anthropometrics indices and body composition including fat mass, body mass index, and hip circumference (P > 0.05). Conclusion: The present study showed that 1000 mg oral L-carnitine had no significant effect on body weight, body mass index, body composition, and hip circumference, but had a significant effect on waist circumference size.

scholarly journals HYPERTENSION

2011 ◽  
Vol 18 (03) ◽  
pp. 440-444
Author(s):  
SHAHANA ARSHI ◽  
MAZHAR BADSHAH ◽  
FARRAH NAZ ◽  
Fakhra Naheed ◽  
Fasih-un- Nisa
Keyword(s):  
Body Mass Index ◽  
Waist Circumference ◽  
Body Mass ◽  
Central Obesity ◽  
The Body ◽  
Medical Sciences ◽  
Hip Circumference ◽  
Waist Hip Ratio ◽  
History Of ◽  
Middle Socioeconomic Status

ABSTRACT…Objective: To evaluate association of hypertension with central obesity in low to middle socioeconomic population. Study design: Descriptive study. Setting: OPD, Filter Clinic. Pakistan Institute of Medical Sciences. Islamabad. Period: June to September 2008. Methods: This study was carried out on 85 patients with history of hypertension. Out of total patients, 27 were males and 58 were females. The ages of the all patients were between 20 to 70 years. Parameters recorded included history, blood pressure, weight, height, waist circumference and hip circumference. The secondary causes were ruled out on the basis of history and physical examination. Data and results were analyzed in SPSS. Results: Out of 85 patients, 74 including 21 males and 53 females had increased Waist Hip Ratio (WHR), 66 including 14 males and 61 females had increased Waist Circumference (WC), while the Body Mass Index (BMI) of 33 including 6 males & 27 females were found obese. It also showed that the females are more prone to obesity. The age group between 41-60 years was most effected. The results indicates that waist hip ratio is the most common indicator of obesity in patients with essential hypertension as compare to waist circumference and body mass index. Conclusions: Hypertension is associated with central obesity in low to middle socioeconomic status. 

scholarly journals A Placebo-Controlled Study on the Treatment of Metabolic Syndrome of Qi Stagnation and Dampness Obstruction Related to Atypical Antipsychotics with Traditional Chinese Medicine (TCM)

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Fengli Sun ◽  
Zhibin Ren ◽  
Yonghong Jiang ◽  
Xiangming Fang ◽  
Naixin Wang ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Negative Symptoms ◽  
Glycosylated Hemoglobin ◽  
The Body ◽  
Control Group ◽  
Study Group ◽  
Hip Circumference ◽  
Significant Difference ◽  
Qi Stagnation

Backgroud. To observe the effects of Liuyu decoction on qi stagnation and dampness obstruction syndrome of metabolic syndrome related to atypical antipsychotics . Methods. 154 schizophrenics who met both the diagnostic criteria of metabolic syndrome and qi stagnation and dampness obstruction syndrome were randomly divided into 2 : 1 groups. The PANSS and Tess were assessed before treatment and at the end of first month, second month, and third month after treatment; blood pressure, weight, waist circumference, hip circumference, blood glucose, glycosylated hemoglobin, high-density lipoprotein, low-density lipoprotein, triglyceride, and cholesterol were also measured at the same four time points. On the basis of continuous antipsychotic treatment, the study group took Liuyu decoction, and the control group took placebo. Results. Of the 154 cases, 102 were in the study group and 52 in the control group. Before and after treatment, there was a slight increase but no significant difference in blood pressure, blood sugar, glycosylated hemoglobin, cholesterol, TG, DHL, and LHL in two groups (P>0.05) and also between the two groups (P>0.05). The body weight, waist circumference, hip circumference, and BMI in the study group decreased, while that in the control group increased from the dividing group to the end of study. At the end of the third month, there was a significant difference in the body weight, waist circumference, hip circumference, and BMI between the two groups (P<0.05). Before and after treatment, there was a significant difference in positive symptoms, negative symptoms, general symptoms, and PANSS in two groups, respectively (P<0.05). The negative symptoms, general symptoms, PANSS, and TESS in the study group were lighter than that in the control group after treatment. Conclusion. Liuyu decoction is not only beneficial to the treatment in body constitution of metabolic syndrome in qi stagnation and dampness obstruction but also beneficial to the improvement of such patients’ mental symptoms and side effects.

The effects of whole grain intake on anthropometric measures in overweight and obese children: a crossover randomised clinical trial

2021 ◽  
pp. 1-7
Author(s):  
Parisa Hajihashemi ◽  
Leila Azadbakht ◽  
Mahin Hashemipour ◽  
Roya Kelishadi ◽  
Parvane Saneei ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Waist Circumference ◽  
Intervention Group ◽  
Randomised Clinical Trial ◽  
Slight Reduction ◽  
Whole Grain ◽  
Obese Children ◽  
Anthropometric Measures ◽  
Before And After ◽  
Grain Foods

Abstract Whole-grain foods have been reported to affect body weight and satiety. However, we are aware of no study in this regard among children. The present study aimed to determine the effects of whole grain consumption on anthropometric measures in overweight or obese children. In this randomised crossover clinical trial, forty-four overweight or obese girls participated. After a 2-week run-in period, subjects were randomly assigned to either intervention (n 44) or non-intervention (n 44) groups. Subjects in the intervention group were given a list of whole-grain foods and were asked to obtain half of their grain servings from these foods each day for 6 weeks. Individuals in the non-intervention group were asked not to consume any of these foods. A 4-week washout period was applied. Then, participants were crossed over to the alternate arm. The measurements were done before and after each phase. Mean age, weight and BMI of participants were 11·2 (sd 1·49) years, 51·2 (sd 10·2) kg and 23·5 (sd 2·5) kg/m2, respectively. Despite the slight reduction in weight and BMI, there were no significant differences in changes in these anthropometric measures. We found a significant effect of whole grain intake on waist circumference (−2·7 v. 0·3 cm, P = 0·04). No significant changes in hip circumference were observed. Changes in the prevalence of overweight, obesity and abdominal obesity were not significantly different. This study indicated a beneficial effect of whole-grain foods on waist circumference in overweight children; however, these foods did not influence weight and BMI.

scholarly journals Waist circumference and waist-hip ratio as screening tools for hypertension in children aged 6–11 years

2019 ◽  
Vol 59 (5) ◽  
pp. 265-70
Author(s):  
Esti Istiqomah ◽  
Dida A. Gurnida ◽  
Dany Hilmanto ◽  
Dzulfikar Djalil Lukmanul Hakim ◽  
Prima Nanda Fauziah
Keyword(s):  
Waist Circumference ◽  
Prevalence Ratio ◽  
Screening Tools ◽  
Hip Circumference ◽  
Roc Curve Analysis ◽  
Anthropometric Parameters ◽  
Predictive Values ◽  
Waist Hip Ratio ◽  
Hypertensive Group ◽  
Hypertension In Children

Background Hypertension in children is associated with obesity. 7 The renin-angiotensin-aldosterone system has been associated with intra-abdominal fat tissue. Anthropometric parameters for determining nutritional status include waist circumference and waist-hip ratio. Many studies have shown that waist circumference and waist-hip ratio are more precise to determine overweight or obese. Objective To determine the usefulness of waist circumference and waist-hip ratio as hypertensive screening tools for children aged 6-11 years. Methods This analytical study with cross-sectional design and multistage cluster sampling method was conducted in August-September 2017 at a primary school in Bandung, West Java, Indonesia. Subjects underwent height, weight, waist circumference, hip circumference, and blood pressure measurements. Receiver operating characteristic (ROC) curve analysis was done to obtain the area under curve (AUC), cut-off point, sensitivity, specificity, and prevalence ratio. Results Subjects were 325 children consisting of 187 males and 138 females. Hypertension was diagnosed in 47 children (37 males and 10 females). Mean waist circumference and waist-hip circumference ratio were significantly higher in the hypertensive group than in the normotensive group. The hypertensive group had a mean waist circumference of 72.6 (SD 12.8) cm, AUC 0.779 (95%CI 0.730 to 0.823; P<0.001), cut-off point >65 cm, sensitivity 66.0%, specificity 76.3%, and prevalence ratio 4.55. This group had mean waist-hip ratio of 0.94 (SD 0.10), AUC 0.724 (95%CI 0.672 to 0.772; P<0.001), waist-hip ratio cut-off >0.91, sensitivity 59.6%, specificity 77.0%, and prevalence ratio 3.73. Conclusion Waist circumference >65 cm or waist-hip ratio >0.91 can be used to screen for hypertension in children aged 6-11 years with negative predictive values of 92.0% and 91.8%, respectively.  

scholarly journals Cholecalciferol v. ergocalciferol for 25-hydroxyvitamin D (25(OH)D) repletion in chronic kidney disease: a randomised clinical trial

2016 ◽  
Vol 116 (12) ◽  
pp. 2074-2081 ◽  
Author(s):  
James B. Wetmore ◽  
Cassandra Kimber ◽  
Jonathan D. Mahnken ◽  
Jason R. Stubbs
Keyword(s):  
Clinical Trial ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Mineral Metabolism ◽  
Substantial Reduction ◽  
Randomised Clinical Trial ◽  
Optimal Method ◽  
Hydroxyvitamin D ◽  
Significant Difference ◽  
25 Hydroxyvitamin D

AbstractPatients with chronic kidney disease (CKD) demonstrate complex mineral metabolism derangements and a high prevalence of vitamin D deficiency. However, the optimal method of 25-hydroxyvitamin D (25(OH)D) repletion is unknown, and trials analysing the comparative efficacy of cholecalciferol and ergocalciferol in this population are lacking. We conducted a randomised clinical trial of cholecalciferol 1250μg (50 000 IU) weekly v. ergocalciferol 1250μg (50 000 IU) weekly for 12 weeks in forty-four non-dialysis-dependent patients with stage 3–5 CKD. The primary outcome was change in total 25(OH)D from baseline to week 12 (immediately after therapy). Secondary analyses included the change in 1,25-dihydroxyvitamin D (1,25(OH)2D), parathyroid hormone (PTH), D2 and D3 sub-fractions of 25(OH)D and 1,25(OH)2D and total 25(OH)D from baseline to week 18 (6 weeks after therapy). Cholecalciferol therapy yielded a greater change in total 25(OH)D (45·0 (sd 16·5) ng/ml) v. ergocalciferol (30·7 (sd 15·3) ng/ml) from baseline to week 12 (P<0·01); this observation partially resulted from a substantial reduction in the 25(OH)D3 sub-fraction with ergocalciferol. However, following cessation of therapy, no statistical difference was observed for total 25(OH)D change from baseline to week 18 between cholecalciferol and ergocalciferol groups (22·4 (sd 12·7) v. 17·6 (sd 8·9) ng/ml, respectively; P=0·17). We observed no significant difference between these therapies with regard to changes in serum PTH or 1,25(OH)2D. Therapy with cholecalciferol, compared with ergocalciferol, is more effective at raising serum 25(OH)D in non-dialysis-dependent CKD patients while active therapy is ongoing. However, levels of 25(OH)D declined substantially in both arms following cessation of therapy, suggesting the need for maintenance therapy to sustain levels.

Randomised clinical trial comparing the perioperative analgesic efficacy of oral tramadol and intramuscular tramadol in cats

2021 ◽  
pp. 1098612X2110404
Author(s):  
Sébastien H Bauquier
Keyword(s):  
Clinical Trial ◽  
Postoperative Pain ◽  
Analgesic Efficacy ◽  
Randomised Clinical Trial ◽  
Rescue Analgesia ◽  
Exact Test ◽  
Pain Scores ◽  
Significant Difference ◽  
American Society ◽  
Induction Of Anaesthesia

Objectives The aim of this study was to evaluate the analgesic efficacy of oral tramadol in cats undergoing ovariohysterectomy. Methods Twenty-four female domestic cats, American Society of Anesthesiologists class I, aged 4–24 months, were included in this positive controlled, randomised, blinded clinical trial. Cats admitted for ovariohysterectomy were allocated to group oral tramadol (GOT, n = 12) or group intramuscular tramadol (GIMT, n = 12). In GOT, tramadol (6 mg/kg) was given orally 60 mins, and saline was given intramuscularly 30 mins, before induction of anaesthesia. In GIMT, granulated sugar in capsules was given orally 60 mins and tramadol (4 mg/kg) intramuscularly 30 mins before induction of anaesthesia. In both groups, dexmedetomidine (0.007 mg/kg) was given intramuscularly 30 mins before induction of anaesthesia with intravenous propofol. Anaesthesia was maintained with isoflurane in oxygen, and atipamezole (0.037 mg/kg) was given intramuscularly 10 mins after extubation. The UNESP-Botucatu multidimensional composite scale was used to conduct pain assessments before premedication and at 20, 60, 120, 240 and 360 mins post-extubation or until rescue analgesia was given. To compare groups, the 60 min postoperative pain scores and the highest postoperative pain scores were analysed via a two-tailed Mann–Whitney test, and the incidences of rescue analgesia were analysed via a Fisher’s exact test; P <0.05. Results There was no significant difference between groups for the 60 min ( P = 0.68) pain scores. The highest postoperative pain score was higher for GIMT compared with GOT ( P = 0.04). Only two cats required rescue analgesia, both from GIMT. The incidence of rescue analgesia was not significantly different between groups ( P = 0.46). Conclusions and relevance In the present study, preoperative administration of oral tramadol at 6 mg/kg to cats provided adequate analgesia for 6 h following ovariohysterectomy surgery.

Vestibular rehabilitation using video gaming in adults with dizziness: a pilot study

2018 ◽  
Vol 132 (3) ◽  
pp. 202-206 ◽  
Author(s):  
J S Phillips ◽  
J Fitzgerald ◽  
D Phillis ◽  
A Underwood ◽  
I Nunney ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Pilot Study ◽  
Vestibular Rehabilitation ◽  
University Hospital ◽  
Control Group ◽  
Rehabilitation Protocol ◽  
Wii Fit ◽  
Significant Difference

AbstractObjective:To determine the effectiveness of vestibular rehabilitation using the Wii Fit balance platform, in adults with dizziness.Methods:A single-site prospective clinical trial was conducted in a university hospital in the UK. Forty patients with dizziness, who would normally be candidates for vestibular rehabilitation, were identified and considered as potential participants. Participants were randomised into either the treatment group (the Wii Fit group) or the control group (standard customised vestibular rehabilitation protocol). Participants were assessed over a 16-week period using several balance and quality of life questionnaires.Results:Both exercise regimes resulted in a reduction of dizziness and an improvement in quality of life scores over time, but no statistically significant difference between the two interventions was identified.Conclusion:This pilot study demonstrated that use of the Wii Fit balance platform resulted in a statistically significant improvement in balance function and quality of life. Furthermore, outcomes were comparable to a similar group of individuals following a standard customised vestibular rehabilitation protocol. The study provides useful information to inform the design and execution of a larger clinical trial.

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