scholarly journals A COMPARATIVE CLINICAL STUDY FOR THE EVALUATION OF SNUHI KSHEERA-HARIDRA CHOORNA LEPA AND DEVADALYADI LEPA IN ARSHAS (2ND DEGREE HAEMORRHOID

2021 ◽  
Vol 9 (11) ◽  
pp. 2678-2683
Author(s):  
Karthika K. L ◽  
Manjunatha Bhat
Keyword(s):  
Clinical Study ◽  
Anal Canal ◽  
Sedentary Lifestyle ◽  
Modern Science ◽  
Bowel Habit ◽  
Common Occurrence ◽  
Fibre Diet ◽  
Causative Factors ◽  
Comparative Clinical Study ◽  
Therapeutic Measures

Today Ano-rectal diseases have emerged as a quite common occurrence with progressive nature. According to the Ayurvedic concept, the aetiology of Arsha is interconnected with Mandagni of the patients. Arsha is a kind of disease that is most unkind towards mankind. A few important causes are sedentary lifestyle, irregular bowel habit, low fibre diet, prolonged straining, sedentary job, suppression of natural urges is some of the causative factors at present. It is a Mamsakeela that obstructs the Gudamarga and thus tortures the patient like an enemy. It can be co-related to haemorrhoids in modern science, the most common ailments of the rectum and anal canal. Intermittent symbolization and embarrassment make people neglect the early stages of haemorrhoids and ultimately end up in complications. The four therapeutic measures of Arshas include Bheshaja chikistha, Shastra karma, Kshara karma, and Agnikarma. Lepa is the foremost effective Bheshaja Chikistha yet less practised and demands further exploration. So based on Arsha Adhyaya of Susrutha Samhita and Arshoghnaadhyaya of Rasa ratnasamucchaya, the present study is intended to evaluate Snuhi ksheera – Haridra Choorna Lepa and Devadalyadi lepa in Arshas. Keywords: Haemorrhoids, Arshas, Snuhi Ksheera- Haridra Choorna Lepa, Devadalyadi Lepa

scholarly journals A Comparative Clinical Study to Evaluate the Efficacy of Guduchyadi Kashaya and Rajrukshadipachana Kashaya in the Management of Eka Kushta w.s.r to Psoriasis

2021 ◽  
pp. 1-9
Author(s):  
Moulika Markonda ◽  
Sowmya S.B
Keyword(s):  
Clinical Study ◽  
Skin Disease ◽  
Skin Diseases ◽  
The Body ◽  
Skin Infections ◽  
Curative Effect ◽  
Causative Factors ◽  
Comparative Clinical Study ◽  
Modern Treatment ◽  
Chronic Course

In Ayurveda, all skin diseases have been described under the umbrella of Kushtha. Ekakusta is considered as the most commonest skin disease that can affect an individual. Acharya Charak has described the involvement of Vata-Kapha in Eka Kushtha. In the present study Eka kushtha is compared with psoriasis due to resemblance of signs symptoms and causative factors with it. Psoriasis is a papulosquamous disorder of the skin, characterized by sharply defined erythematosquamous lesions this illness exhibits a prompt response if treated carefully, left it may run a very chronic course extending into larger area of the body. Ayurveda focuses more on curative management than palliative management. The drug used in the treatment of Ayurveda does not have complications like modern treatment. Repeated Sodhana prevent the recurrence of the disease. Similarly various preparations have been advocated for the management of Psoriasis. The drugs used in this study are Guduchyadi Kashaya & Rajrukshadi Pachana Kashaya. Both the Kashayas are said to be effective in skin diseases. As per Yogaratnakara, Guduchyadhi Kwath has been mentioned as one of the drug having curative effect on all types of Kustha. Hence for present study the orally Guduchyadi Kwath is taken for EkaKustha treatment. The drugs in Guduchyadi Kwatha are Kusthaghana, Twachya, Swedal, Tridosh shamaka, as well as with Rasayan properties, which is beneficial to break down the pathogenesis of disease. As per Gadanigraha, as mentioned in Kayachikitsakhanda, Rajvrukshadipachana Kashaya is mentioned for the treatment of Ekakushtha. Ingredients in Rajvrukshadi Pachana Kashaya reduce Kapha dosha and most of them act on the skin. Kwatha dravyas are Rasadushtihara, Kaphapittahara, Deepana, Twachya, and also having antibacterial, antimicrobial, antiparasitic and anti-inflammatory properties, Hence, it is helpful for clearing the skin infections.

scholarly journals A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF RAJAPRAVARTAKA CHURNA AND HINGUVACHADI CHURNA IN PCOS

2021 ◽  
Vol 9 (10) ◽  
pp. 2397-2403
Author(s):  
Shabeena. I. Attar ◽  
Shivale. Digamber
Keyword(s):  
Clinical Study ◽  
Polycystic Ovarian Syndrome ◽  
Causative Factors ◽  
Wide Range ◽  
Calorie Diet ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
Disor Ders ◽  
Ovarian Syndrome

Polycystic Ovarian Syndrome (PCOS) is the most common health problem caused by a disproportion of reproduc- tive hormones with the ovarian expression of various metabolic disorders and a wide range of clinical features such as obesity, menstrual abnormalities and hyperandrogenism. In this modern era, the erratic lifestyle, high- calorie diet and deskbound jobs have resultantly expanded the spread of hormonal disparities and menstrual disor- ders have led to an increased prevalence of PCOS up to 20-30 %. There are similar conditions explained in the classics under the context of Pushpaghni jataharini. The treatment should be Kapha-Vata hara, vatanulomana, dipana, pittavardhaka along with avoidance of causative factors. Considering the above facts, Rajapravartaka churna and Hinguvachadi churna were selected for the study. The present study was aimed to bring out the effect of Ayurveda in PCOS, which is safe and non-hormonal. Objectives of the study: 1) A comprehensive study of PCOS and its congruence in Ayurveda. 2) To study the efficacy of Rajapravartaka churna and Hinguvachadi churna in PCOS and to compare its efficacy. Materials and Methods: A randomized comparative clinical study of two groups, consisting of 20 patients in each group. Group A - Rajapravartaka churna orally in the dose of 3gm twice daily along with tila kwata as an anupana 50ml; before food for a period of two consecutive cycles. Group B was given Hinguvachadi churna orally in the dose of 250mg twice daily along with water; before food for a period of two consecutive cycles. Results and Interpretation: The study has shown a statistically signifi- cant difference between each group in its efficacy. Conclusion: Rajapravartaka churna showed better results thanHinguvachadi churna while taking the account of the percentage of each criterion. Keywords: Polycystic ovarian syndrome, Pushpaghni Jataharini, Rajapravartaka Churna, Hinguvachadi Churna.

scholarly journals A RANDOMISED SINGLE BLIND COMPARATIVE CLINICAL STUDY ON THE EFFICACY OF ANJANI-A FOLKLORE HERB AND KRISHNA TILA KALKA IN THE MANAGEMENT OF PCOS W.S.R TO OLIGOMENORRHOEA

2021 ◽  
pp. 12-16
Author(s):  
Sridevi. M ◽  
B.S.Savadi
Keyword(s):  
Cerebral Cortex ◽  
Clinical Study ◽  
Side Effects ◽  
Modern Science ◽  
Holistic Approach ◽  
Menstrual Irregularity ◽  
Control Drug ◽  
Comparative Clinical Study ◽  
Trial Drug ◽  
Single Blind

Menstruation is the end point of series of events which begin in the cerebral cortex and hypothalamus and ends at the uterus in the hypothalamic pituitary –ovarian uterine axis. Any break in this axis creates Menstrual Problems. PCOS is one such condition associated with abnormal gonadotropic secretion which in turn lead to menstrual irregularity acne and hirsutism- Its prevalence ranging from 2.2% to 26% with age ranging from 18-45 years. In modern science PCOS is managed by down regulating HPO axis using Hormonal Pills which have their own side effects. Therefore complete, comprehensive and holistic approach towards its understanding & treatment is the need of the age. Ayurveda has no direct correlation to PCOS. There are similar condition acc to symptoms are explained under the concept of Pushpaghni, Jathaharini. Here under PCOS w.s.r. to Oligomenorrhoea, interval between menses, duration of flow, amount of flow and other symptoms like pain are considered. The effect of Anjani vati (Trial drug) is compared with Krishna Tila Kalka (Control Drug) in two groups containing 30 patients each.

A Comparative Clinical Study of Vamana and Virechana in the management of Tamaka Swasa

2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Dr. Akhilanath Parida ◽  
Dr.Satyasmita Jena
Keyword(s):  
Clinical Study ◽  
Young People ◽  
Comparative Study ◽  
Bronchial Asthma ◽  
Economic Burden ◽  
Age Groups ◽  
Modern Science ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

In Tamaka Swasa there is condition of (1) Yapyatva (palliative) and (2) Chirakaritva (chronic) and (3) more Kshaya of Rasha Dhatus (decrease in the immunity) in this condition, the patient need a special type of management which can combated above three condition. Tamaka Swasa which is compared with Bronchial Asthma is a common problem and its prevalence is in all age groups irrespective of sex. Among five types of Swasa Roga, Tamaka Swasa is one of the most common and very well explained in Ayurvedic classics which can be compared with asthma in modern science. Mortality due to asthma is not comparable in size to the day today effect of the disease. Although largely avoidable, asthma tends to occur in epidemics and effect young people. The human and economic burden associated with this condition is severe. The study is carried out as a comparative study of Vamana and Virechana. In this Group (Group–A), Vamana was given to the patients. Total 15 patients were registered. In this Group (Group–B), patients were taken for Virechana. Total 15 patients were registered.

A comparative clinical study of classical and non-classical Siravyadha in Vipadika

2019 ◽  
Vol 4 (04) ◽  
Author(s):  
Lalita Gaonkar ◽  
Gururaja H ◽  
Jeejo Chandran O
Keyword(s):  
Clinical Study ◽  
Effective Treatment ◽  
Severe Pain ◽  
Skin Diseases ◽  
Signs And Symptoms ◽  
Comparative Clinical Study ◽  
Therapeutic Measures ◽  
Effective Remedy

In Ayurveda all the skin diseases are described under single heading i.e. ‘Kushta’ which are further divided into Mahakushta and Kshudrakushta. Vipadika is among the 11 types of Kshudra Kushta involving Vata Kapha mentioned in classics characterized by ‘Panipada Sphutana’ (Fissures in Palms and Soles) and ‘Tivravedana’ (Severe Pain). On basis of its signs and symptoms it can be correlated with ‘Palmoplantar Psoriasis’. Kushtachikitsa is classified into Shodhanam, Shamanam and Nidanparivarjana amongst which Shodhana Chikitsa is of greater significance in skin diseases, and Raktamokshana is considered to be a shortest and effective treatment in the management of skin diseases. Siravyadha is a type of Panchashodhana described by Acharya’s as an effective remedy in number of disease conditions. Acharya Sushruta and Vagbhata has mentioned that Siravyadha is half treatment in Shalyatantra as Basti is the half treatment in Kayachikitsa. Diseases which do not get pacified so quickly by therapeutic measures like Snehana, Swedana etc. are pacified by Siravyadha.

scholarly journals A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFECT OF VRIKSHAMLA TWAK KASHAYA AND DASHAMOOLA KASHAYA IN UDAVARTHINI YONIVYAPAT

2021 ◽  
Vol 9 (10) ◽  
pp. 2303-2309
Author(s):  
Sahana G ◽  
Shivale Digambar P ◽  
Kavitha B.K ◽  
Manju Parvathy
Keyword(s):  
Clinical Study ◽  
Sedentary Lifestyle ◽  
Research Work ◽  
Normal Function ◽  
Duration Of Treatment ◽  
Natural Event ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
Trial Drug

Menstruation is a physiological, natural event in the reproductive stage of the female. Due to a sedentary lifestyle and lack of self-care, stress, untimely food and other factors, many gynaecological problems occur and one of the most common among them is Dysmenorrhea. Painful menstruation is the most common cause which disturbs the mental state of the woman also affecting her day to day activities during the cycle. Pain is the Pratyatma Lak- shana of Vata vikruti mentioned in Ayurveda. Artava Nishkramana is the normal function of Apana vayu which moves in Pratiloma gati and obstructs the pathway of Artava. In our Classics, most of the gynaecological prob- lems are discussed under Yonivyapat. Udavartini Yonivyapat can be co-related and defined as painful menstrua- tion i.e. Dysmenorrhea. Considering the prevalence of dysmenorrhea in the present era, the trial drug Vrikshamlatwak kashaya which possess the properties such as Shoolprashamana and Vatahara was selected to evaluate its effect in the management of Udavartini yonivyapat. Objectives: To compare and evaluate the effect of Vriksham- la Twak kashaya and Dashamoola kashaya in Udavarthini yonivyapat w.r.s primary dysmenorrhea. Methodolo- gy: This research work was a randomized comparative clinical study of 40 patients suffering from symptoms of Udavartini Yonivyapat, who were randomly selected and categorized into 2 groups of 20 patients each. Group A was treated with Vrikshamla Twak kashaya and group B with Dashamoola Kashaya. Both Kashayas were given in Apanakaala (before food) with Sukhoshna Jala as Anupana. Duration of Treatment: 10 days (Starting 7days before the commencement of cycle till 3rd day of the menstrual cycle) for 3 consecutive cycles. Results and In- terpretation- Both the groups showed statistically significant results. Statistically, there was no significant differ- ence between the groups. Conclusion: Both Vrikshamla Twak kashaya and Dashamoola Kashaya had an equal effect in treating Udavartini Yonivyapat. Keywords: Udavartini, Dysmenorrhea, Vrikshamla Twak Kashaya, Dashamoola kashaya.

scholarly journals A Comparative Clinical Study on Vamana and Virechana Karma in the Management of Ekakushtha with Special Reference to Psoriasis

2021 ◽  
pp. 27-35
Author(s):  
MD Haidar ◽  
Sukumar Ghosh ◽  
Supriya Bhattacharya ◽  
Asish Kumar Das ◽  
Rajarshi Chaudhuri
Keyword(s):  
Statistical Analysis ◽  
Clinical Study ◽  
Skin Lesion ◽  
World Wide ◽  
Modern Science ◽  
Large Area ◽  
The World ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Ekakushtha is one of the Kshudra Kushtha described in Ayurvedic classics. It predominantly involves Vata and Kapha Dosha and characterized by Asvedanam (Anhidrosis), Mahavastu (large area of involvement), Matsyashakalopamam (scaling), Krishna Aruna Varna (black or reddish brown skin lesion), Kandu (itching) and Rukshata (dryness). In modern science it can be co-related with Psoriasis. According to W.H.O. the world wide prevalence of Psoriasis is 2-3% (April, 2013). In India prevalence of Psoriasis varies from 0.44 to 2.88%. Acharya Charaka mentioned that treatment of Ekakushtha is to be carried out according to involvement of excessive Dosha. It is Bahudosha (excessively aggravated Dosha) and Chirkari (chronic) Vyadhi (disease). In this condition Shodhana Chikitsa (purificatory measures) is best. So in this present study Vamana Karma and Virechana Karma is chosen for the treatment of Ekakushtha. Here 60 cases of Ekakushtha (Psoriasis) were divided into two groups. Group A (30 patients) were subjected to Vamana Karma. Group B (30 patients) were subjected to Virechana Karma. The statistical analysis reveals that Vamana Karma is statistically more significant in the management of Ekakushtha. Here both the therapies i.e. Vamana Karma and Virechana Karma were effective in the treatment of Ekakushtha. But Vamana Karma was more effective than Virechana Karma.

scholarly journals A comparative Clinical Study to Evaluate the Efficacy of Anuvasan Basti with Brahatchaglyadi Ghritam and Guggulutiktam Ghritam in the management of Gridhrasi (Sciatica): A Study Protocol

2021 ◽  
pp. 119-136
Author(s):  
Arun Kumar Gupta ◽  
Shweta Parwe ◽  
Trupti Gupta ◽  
Milind Nisargandha
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Clinical Study ◽  
Modern Science ◽  
Control Group ◽  
Low Back ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
Interventional Group

Background: Gridhrasi is such a Ruja Pradhaana Vatavyadhi. In Gridhrasi intense shooting pain characteristically radiates from Sphika (gluteal region) to Pada (foot). Based on symptoms of Gridhrasi, it can be equated with the disease sciatica in modern science. The lifetime incidence of low back pain is 50-70%, with Sciatica more than 40%. Charaka has considered Basti therapy as half of the disease's treatment, while some authors consider it as the complete remedy for all the ailments. Basti is one of the unique procedures explained for the management of Vatavyadhi (Neurological Disorder) where Gridhrasi (Sciatica) is being the predominant of Vata dosha, Basti is being used widely for the management of Gridhrasi (Sciatica). Therefore we have taken the Basti modality for the treatment of Gridhrasi (Sciatica). Hence the study is carried to evaluate the effect of Anuvasanbasti with Brihachagalyadi Ghritam & Guggulutiktaka Ghritam in the management of Gridhrasi (Sciatica). Aims and Objectives: Evaluate Anuvasan Basti's efficacy with Brihatchagalyadi Ghritam & Guggulutiktaka Ghritamin the control of Gridhrasi (Sciatica) and to compare the effectiveness of Brihachagalyad Ghritam & Guggulutiktak Ghritam Anuvasan Basti in the direction of Gridhrasi. Methodology: Procedure: This study, a total of 66 patients, will be separated haphazardly divided into 2 groups (33 in each). In Group A (Interventional Group)- will Treat with Brihachagalyadi Ghritam as an Anuvasan Basti in increasing dose pattern for nine days and Group B (Control Group ) –patients will Treat with Guggulutiktaka Ghritam as an Anuvasanbasti in increasing dose pattern for nine days. The evaluation will be recorded on 0 and 9thday. Conclusion: It may be more beneficial and more effective in pain as well as other subjective and objective parameters.

scholarly journals A COMPARATIVE CLINICAL STUDY ON THE EFFECTIVENESS OF BHARANGYADI CHOORNA AND VYAGHRI CHOORNA IN TAMAKA SWASA (BRONCHIAL ASTHMA)

2020 ◽  
pp. 70-78
Author(s):  
Devanand E ◽  
K Ravindra Bhat
Keyword(s):  
Clinical Study ◽  
Bronchial Asthma ◽  
Modern Science ◽  
Signs And Symptoms ◽  
Wilcoxon Test ◽  
Control Group ◽  
Inflammatory Disorder ◽  
Chronic Inflammatory Disorder ◽  
Comparative Clinical Study ◽  
Group B

Ayurveda classics mentioned various types of Swasa and Tamaka Swasa is one among them. Tamakaswasa is manifested by aggravated Pranavayu by the obstruction of Kapha. In this case treatment should be to clear out Pranavaha srotas, pacify Vata and remove the blockage due to Kapha. In modern science Tamaka Swasa is correlated with Bronchial Asthma. It’s a chronic inflammatory disorder of the airways in which the chronic inflammation causes an associated increase in airway hyper responsiveness that leads to recurrent episodes of asthmatic exacerbation. Modern science has no permanent cure of Tamaka Swasa, that’s why it is necessity to search herbal and herbo-mineral preparations for the treatment of disease. Present Study was conducted to reduce the symptoms of Tamakaswasa. Bharangyadi Choorna and Vyaghri Choorna have the properties of Kapha Vata hara, Agni Deepana, Pachana, Anulomana, Srotoshodhana, anti-asthamatic and anti-inflammatory property. Materials and Method: Patients who have symptoms of Tamakaswasa fulfill the inclusion criteria were given with Bharangyadi Choorna 4gm thrice a day along with Ardraka Swarasa as Anupana in the trail group i.e., group A and Vyaghri Choorna 4gm thrice a day along with honey as Anupana in the control group i.e. group B. It is a comparative clinical study with 30 patients in each group for 30 days. Analyzing the signs and symptoms, PEFR after each 10 days, Wilcoxon test was done for comparing the effectiveness of treatment between two groups. Comparative analysis of the overall effect of the treatments in both the groups was done by statistically done by Mann-Whitney test. Results: There was statistically significant change in all the signs and symptoms and PEFR after treatment and follow up. All the signs and symptoms have P ≤ 0.05. Conclusion: Bharangyadi Choorna has shown highly significant reduction in the symptoms like Swasakrichratha, Peenasa, Kasa, Ghurghuraka, Krichrabhashana, Shushkasya and PEFR. On comparison between the two groups, Bharangyadi choorna showed a better result in improvement of symptoms- Swasakrichratha, Peenasa, Kasa, Ghurghuraka, Krichrabhashana, Shushkasya and objective parameter- PEFR. Hence H2 hold good.

Comparative Clinical Study of the Effects of Disulfiram and Calcium Carbimide. I. Side Effects

1960 ◽  
Vol 21 (4) ◽  
pp. 642-654 ◽  
Author(s):  
Juan Marconi ◽  
Guido Solari ◽  
Sergio Gaete ◽  
Luisa Piazza
Keyword(s):  
Clinical Study ◽  
Side Effects ◽  
Comparative Clinical Study
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