scholarly journals CLINICAL EVALUATION OF THE EFFICACY OF LEKHANBASTI AND MEDOHARAVIDANGADILAUHA IN THE MANAGEMENT OF DYSLIPIDEMIA

2021 ◽  
Vol 9 (7) ◽  
pp. 1362-1365
Author(s):  
Noor Sayeda Shabnam Ahmed ◽  
Om Prakash Gupta ◽  
Bishnu Prasad Sarma
Keyword(s):  
Lipid Profile ◽  
Clinical Evaluation ◽  
Oral Intake ◽  
Before And After ◽  
Significant Change ◽  
Ethical Clearance

This study was conducted to evaluate the efficacy of lekhanbasti and medoharavidangadilauha in the management of dyslipidemia. Consent from all the selected patients was taken before the study after explaining to them about the disease and the procedure. Ethical clearance was accredited by the ethical committee of Government Ayurvedic College and Hospital Guwahati, Assam. Patients from IPD and OPD of the department of Kayachikitsa of the aforesaid institute were chosen. Lekhanbasti niruha and tiltaila anuvasana on alternate days was administered for 8 days Follow up was done at an interval of 30,60 and 90 days. Oral intake of medoharavidangadilauha was advised during these 90 days. The basti was repeated in the follow-up period. After comparing the fasting lipid profile before and after treatment it was found that there was a significant change in it. Keywords: Dyslipidemia, Lekhanbasti, Medoharavidangadilauha, Medoroga, Fasting lipid profile.

Refractive, Tomographic and Biomechanical Outcomes after Implantation of Ferrara ICRS in Keratoconus Patients

2012 ◽  
Vol 1 (1) ◽  
pp. 16-21 ◽  
Author(s):  
José M Salgado-Borges ◽  
Cláudia Costa-Ferreira ◽  
Manuel Monteiro ◽  
José Guilherme-Monteiro
Keyword(s):  
Wilcoxon Test ◽  
Before And After ◽  
Biomechanical Parameters ◽  
The Mean ◽  
Significant Change ◽  
Corneal Flattening

ABSTRACT Background Nowadays, ICRS are a step in the treatment of keratoconus. The purpose of this study was to evaluate the refractive effect and the tomographic and biomechanical parameters in keratoconus patients implanted with Ferrara ICRS, and their stability after 18 months. Materials and methods Twenty eyes of 20 keratoconus patients implanted with ICRS were evaluated. The average follow-up was 18 months. UDVA, CDVA, biomicroscopy, tomography (Pentacam) and biomechanics (ORA) of the cornea were evaluated before and after surgery. For the comparison of groups, the Wilcoxon test was used. Results The mean UDVA improved from 1.00 to 0.30 and the mean CDVA improved from 0.51 to 0.12; both were statistically significant (p = 0.0001). The average keratometry decreased from 50.7D to 47.5D (p = 0.0003), and the average astigmatism decreased from 5.5D to 3.5D (p = 0.0058). The mean CCT did not change significantly after surgery, but the mean TPP increased from 441.2 to 455.2 µm (p = 0.004). There was a significant reduction in the anterior cornea elevation, both the central (from 16.2-8.8; p = 0.0066) and the minimum (from–43.2 to −57.1; p = 0.0228). No significant change was found for posterior corneal elevation and for biomechanical parameters (hysteresis or CRF). Discussion There was a significant improvement of UDVA and CDVA after ICRS implantation, in keratoconic eyes. There was a significant and stable corneal flattening, and a decrease of the astigmatism. Corneal biomechanic parameters did not change. How to cite this article Salgado-Borges JM, Costa-Ferreira C, Monteiro M, Guilherme-Monteiro J, Torquetti L, Ferrara P, Ambrósio R Jr. Refractive, Tomographic and Biomechanical Outcomes after Implantation of Ferrara ICRS in Keratoconus Patients. Int J Keratoco Ectatic Corneal Dis 2012;1(1):16-21.

Autoimplantation technique in the treatment of anogenital warts: a clinico-immunological study

1996 ◽  
Vol 7 (1) ◽  
pp. 55-56 ◽  
Author(s):  
N Usman ◽  
K Udayashankar ◽  
S Subramanian ◽  
S P Thyagarajan
Keyword(s):  
Immune Responses ◽  
Clinical Cure ◽  
Immune Status ◽  
Control Group ◽  
Immunological Study ◽  
Anogenital Warts ◽  
Matched Group ◽  
Before And After ◽  
Significant Change

An autoimplantation technique was adopted in the treatment of 50 cases of anogenital warts and was compared with the conventionally used podophyllin regimen in a matched group of 50 patients. They were assessed with 15 untreated subjects in a control group for the rate of clinical cure after 6 weeks, recurrence after 1 year follow up and for humoral and cell mediated immune responses before and after treatment. In the podophyllin group, 70% of patients were cured after 6 weeks while in autoimplantation, only 44% of patients were cured, and none in the control group had natural remission of warts without any treatment. After 1 year all the cured cases (100%) that completed follow up had recurrence of warts with podophyllin treatment, while none had recurrence of lesions in the autoimplantation group. Results of the humoral and cell mediated immune (CMI) response studies revealed that autoimplantation technique significantly augmented both humoral and CMI responses while there was no significant change in the immune status after podophyllin treatment (P>0.001).

scholarly journals Chronological Impact of Earthquakes on Blood Pressure: A Literature Review and Retrospective Study of Hypertension in Haiti Before and After the 2010 Earthquake

2021 ◽  
Vol 8 ◽  
Author(s):  
Ayman R. Fath ◽  
Amro Aglan ◽  
Jeri Platt ◽  
Jordan R. Yaron ◽  
Kyle S. Varkoly ◽  
...  
Keyword(s):  
Literature Review ◽  
Chart Review ◽  
Retrospective Studies ◽  
Retrospective Chart Review ◽  
Chronic Effects ◽  
Significant Difference ◽  
Before And After ◽  
Early Health ◽  
Significant Change

Objective: We review prior studies on the incidence of hypertension (HTN) after earthquakes and present a retrospective analysis of HTN after the 2010 earthquake in Haiti.Methods: Prior reports on HTN incidence were reviewed and a retrospective chart review for diagnosis of HTN in 4,308 patient charts was performed over a 7 year period (five clinics). A retrospective cohort study (RCS) was then performed on 11 patients with linear follow-up.Results: The Literature review revealed a significant increase in acute and subacute HTN following earthquakes. However, the chronic effects of earthquakes varied. Our chart review uncovered no significant difference in diagnosed HTN in a Fort-Liberté clinic 128 kilometers (km) distant and 4 weeks post-event. A secondary linear RCS for 11 individuals, prior to and after the earthquake, also did not detect a significant change in HTN prevalence.Conclusion: Prior studies demonstrate acute and subacute, increases in HTN after earthquakes, but late changes have varied. Retrospective studies in the Fort-Liberté clinic, 128 km distant and 4 weeks post-event, revealed no significant change in HTN, confirming prior findings that changes in HTN after earthquakes are early and local events. Further work examining HTN after earthquakes is needed to improve early health care after natural disasters.

EP.WE.824Effect of bariatric surgery on gut permeability in humans: a systematic review

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
James O'Brien ◽  
Denise Robertson ◽  
Bruce Griffin ◽  
Timothy Rockall ◽  
Chris Pring
Keyword(s):  
Systematic Review ◽  
Bariatric Surgery ◽  
Intestinal Permeability ◽  
Meta Analysis ◽  
Oral Intake ◽  
Permeability Change ◽  
Before And After ◽  
Small Intestinal ◽  
Malabsorptive Operations

Abstract Aims Altered intestinal permeability (“leaky gut”) is associated with obesity. Several mechanisms have been suggested to explain the harmful sequalae that follow permeability change such as inflammation, alteration to the microbiome and onset of insulin resistance. Studies describe bariatric surgery as having varying effects on intestinal permeability. We aim to summarise and review the literature. Methods A systematic review was performed using MEDLINE, EMBASE, and Scopus to identify studies in humans that investigated permeability change after bariatric surgery. Results 5 studies were identified, all cohort. Heterogeneity precluded meta-analysis. All calculated permeability change following oral intake of different sugar solutions. Two studies described a reduction in gastroduodenal permeability post sleeve gastrectomy (SG), one from an increased baseline compared to lean controls. Two described an increase in small intestinal permeability after “malabsorptive” operations (biliopancreatic diversion and duodenal switch). Two found decreased small intestinal permeability at one month post Roux-en-Y gastric bypass and six months post SG. One including only SG had opposite findings of increased small intestinal permeability at 6 months. The only colonic change reported was increased permeability also 6 months post SG. Conclusion Research found both increased and decreased permeability of the small intestine. Two studies found reduced gastroduodenal permeability post operatively. Evidence regarding the effect of bariatric surgery on the permeability of the gastrointestinal tract and specifically the colon is limited and follow up, operation type and small numbers limit meaningful comparison. Further study into this crucial aspect of obesity both before and after surgery is needed.

Long-term Follow-up of the Green-Watermann Osteotomy for Hallux Limitus

2002 ◽  
Vol 92 (10) ◽  
pp. 543-554 ◽  
Author(s):  
Jason B. Dickerson ◽  
Richard Green ◽  
Donald R. Green
Keyword(s):  
Clinical Evaluation ◽  
Average Length ◽  
Metatarsophalangeal Joint ◽  
First Metatarsophalangeal Joint ◽  
Hallux Limitus ◽  
Before And After ◽  
Chief Complaints ◽  
Long Term Follow Up

The authors undertook a retrospective analysis of the long-term efficacy of the Green-Watermann procedure for the treatment of painful hallux limitus or rigidus. Questionnaires were sent to 80 consecutive patients who had such procedures performed between 1990 and 1999. Medical records and radiographs were reviewed for the 32 patients who completed the questionnaires, representing 40 Green-Watermann procedures. Twenty-four patients were able to return for clinical evaluation. The average length of follow-up was 4 years (range, 1 to 10 years). The questionnaires addressed pain before and after surgery, function after surgery, complications, and overall impression and satisfaction. Nearly all of the patients (30 of 32; 94%) reported that surgery had significantly relieved their hallux joint pain, and a slightly smaller proportion (28 of 32; 88%) felt that their chief complaints were at least 70% improved. Clinical evaluation revealed adequate range of motion at the first metatarsophalangeal joint. It is concluded that the Green-Watermann procedure is an effective treatment approach for hallux limitus and rigidus, resulting in a significant reduction in pain, an increase in function, and a high degree of patient satisfaction. (J Am Podiatr Med Assoc 92(10): 543-554, 2002)

scholarly journals Maternal Experience of Domestic Violence, Associations with Children’s Lipid Biomarkers at 10 Years: Findings from MINIMat Study in Rural Bangladesh

Nutrients ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 910
Author(s):  
Shirin Ziaei ◽  
Ruchira Tabassum Naved ◽  
Anisur Rahman ◽  
Rubhana Raqib ◽  
Eva-Charlotte Ekström
Keyword(s):  
Domestic Violence ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipid Biomarkers ◽  
Maternal Experience ◽  
Before And After ◽  
Controlling Behavior ◽  
Controlling Behaviors

The consequences of maternal experience of Domestic Violence (DV) on their children’s cardio-metabolic risk factors are unclear. We aimed to assess if maternal exposure to any or a specific form of DV (i.e., physical, sexual, emotional and controlling behaviors) before and after childbirth was associated with their children’s lipid biomarkers at the age of 10 years. A current observational sub-study of a larger MINIMat trial included a cohort of 1167 mothers and their children. The conflict tactic scale was used to record women’s experience of lifetime DV before and after childbirth at week 30 of pregnancy and at a 10-year follow up, respectively. Five ml of fasting blood sample was collected from the children to evaluate their lipid profile. Children of women who experienced any DV before childbirth had lower Apo A (βadj −0.04; 95% CI: −0.08, −0.01). Women who experienced physical DV both before and after childbirth had children with higher triglycerides (βadj 0.07; 95% CI: 0.01, 0.14). Children whose mother experienced sexual DV before birth had lower Apo A (βadj −0.05; 95% CI: −0.08, −0.01) and High Density Lipoprotein (HDL) (βadj −0.05; 95% CI: −0.10, −0.01) as well as higher Low Density Lipoprotein (LDL) (βadj 0.17; 95% CI: 0.05, 0.29) and LDL/HDL (β 0.24; 95% CI: 0.11, 0.38). However, levels of LDL (βadj −0.17; 95% CI: −0.28, −0.06), LDL/HDL (βadj −0.12; 95% CI: −0.25, −0.00) and cholesterol (βadj −0.13; 95% CI: −0.25, −0.02) were lower among the children of mothers who experienced controlling behavior after childbirth. Results from the current study suggest that maternal experience of physical or sexual DV might negatively affect their children’s lipid profile at the age of 10 years.

Abstract 034: The Effect Of Simvastatin On P-wave Dispersion And Echocardiographic Parameters Among Hypertensive Patients

2013 ◽  
Vol 113 (suppl_1) ◽  
Author(s):  
Pamela M Pomer ◽  
Janet W Elcano
Keyword(s):  
Statin Therapy ◽  
Wave Dispersion ◽  
Left Ventricular ◽  
P Wave ◽  
Volume Index ◽  
P Wave Dispersion ◽  
Hypertensive Patients ◽  
Before And After ◽  
Significant Change

Introduction: Rising evidence suggests that statins have a positive effect on the prevention of occurrence of atrial fibrillation (AF) in hypertensive patients. P-wave dispersion (PWD) has been known to be an electrocardiographic predictor for the development of AF. We therefore aimed to investigate on the possible effects of statins on p-wave dispersion in hypertensive patients. Method: A total of 27 patients (22 females; mean age, 45±11 years) with hypertension and without history of AF were included in this prospective study. P wave durations and PWD, left ventricular mass (LVMI), left atrial volume index (LAVI), and ratio of early diastolic transmitral flow velocity (E) to early diastolic mitral annular velocity (e) (E/e’) were measured and compared before and after statin therapy (simvastatin 40mg/day for 3 months). Results: After 3 months of statin therapy, there was no significant change in PWD (pre-statin 39.7 ±10.7, post-statin 33 ± 8.8, p-value 0.30). Baseline and follow up blood pressure, heart rate, LVMI, LAVI and E/e’ ratio were not significantly different before and after simvastatin therapy. No patient developed AF during follow up. Conclusion: Simvastatin (40mg/day) therapy for 3 months did not show significant change on PWD, LVMI, LAVI and E/e’ ratio in hypertensive patients.

Melatonin Improves Lipid Profile and Ameliorates Lipid Peroxidation in Patients with Chronic Kidney Disease.

2018 ◽  
pp. 38-45
Keyword(s):  
Lipid Peroxidation ◽  
Placebo Group ◽  
Lipid Profile ◽  
Kidney Diseases ◽  
Oxidized Ldl ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Before And After ◽  
Inhibit Lipid Peroxidation ◽  
Controlled Clinical Study

Dyslipidemia and oxidative modifications of lipid are frequently associated in patients with chronic kidney diseases (CKD) and considered the most important risk factors for cardiovascular events. Melatonin is a well-known potent antioxidant and has beneficial effect on lipid metabolism. the study was designed to evaluate if Melatonin could improve lipid profile and ameliorates lipid peroxidation. This single blind placebo controlled clinical study carried out on 41 patients with CKD who were randomized into two groups, control groups (n=20) those who received placebo cap and melatonin group those who received 5mg melatonin (n=21). Lipid profile [total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL-C), low-density lipoprotein (LDL-C)] and parameters of lipid peroxidation [oxidized LDL (oxLDL) and malondialdehyde (MDA) were measured before and after 12 weeks of the treatment. After 12 weeks of treatment, melatonin significantly increased HDL-C and decreased LDL-C compared to the initial value. The elevation in HDL-C and reduction in LDL-C were significantly different from that in placebo group. Also, both oxLDL and MDA levels significantly lowered by melatonin compared to the baseline and to the placebo group. Collectively, the results of our study showed that melatonin has advantageous effect on lipid profile and inhibit lipid peroxidation in patients with CKD.

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