scholarly journals A Comparative Clinical Study to Evaluate the Effect of Shamana Sweda Followed by Nirgundi Guggulu in Vaatakantaka with Special Reference to Calcaneal Spur Amongst Female Population

2021 ◽  
pp. 1-8
Author(s):  
Suma Astagimath ◽  
S G Chavan ◽  
Madhusudan Kulkarni
Keyword(s):  
Clinical Trials ◽  
Clinical Study ◽  
General Population ◽  
Female Population ◽  
High Heel ◽  
Calcaneal Spur ◽  
Treatment Measures ◽  
Comparative Clinical Study ◽  
A Prospective Study ◽  
Clinical Trials Registry

Vatakantaka is characterized by the pain in the heel region and included in the vatavyadhi by Acharya Sushruta. It is common in about 10% of general population. Women are twice more prevalent than men. Vatakantaka is mainly caused due to vitiation of Vatadosha and continuous pressure on the heel region. It can be co-related with Calcaneal spur. It is more prevalent in female due to life style postures like standing for longer period, wearing high heel shoes. Various treatment measures for the management of Vatakantaka are given in the classics of Ayurveda. Siravyadha,Agnikarma and Eranda taila pana are the main chikitsa of Vatakantaka. Achrya Charaka said Vatakantaka is Sweda sadhya Vyadhi. So in this present study, treatment is given with swedana followed by Shamanoushadhi.  Here 40 cases of Vatatakantaka vis- a -vis Calcaneal spur were  devided in to two groups and subjected to Dashamula churna pinda sweda  and valuka sweda for 7 days, followed by Nirgundi Guggulu for 30 days. Patients  showed significant results in subjective and objective parameters. The present clinical study has been registered as a Prospective study in clinical trials registry- India (CTRI). Register number – CTRI/2019/11/022132

scholarly journals A COMPARATIVE CLINICAL STUDY OF ISHTIKA SWEDA AND NADI SWEDA ALONG WITH RASNADI GUGGULU IN THE MANAGEMENT OF VATAKANTAKA

2021 ◽  
Vol 9 (9) ◽  
pp. 2021-2028
Author(s):  
Gouri Tanksali ◽  
Uma Patil
Keyword(s):  
Clinical Study ◽  
Treatment Modalities ◽  
Treatment Methods ◽  
Calcaneal Spur ◽  
Comparative Clinical Study ◽  
Group A ◽  
High Heels ◽  
Group B

Vatakantaka is one of the Vata Vyadhi which gives pricking pain in the heels and causes discomfort in the day-to- day activities. It can be co-related with Calcaneal Spur. It is caused due to wearing high heels and walking with bare feet. Among the various treatment modalities, Abhyanga and Sweda is the best treatment for Vata vyadhi. Hence the present study brings to light the role of Swedana along with Rasnadi Guggulu in the management of Vatakantaka. To evaluate the effect of Istika sweda over Nadi Sweda along with Rasnadi guggulu in management of Vatakantaka. In the present study, 40 patients of vatakantaka were selected incidentally and placed randomly into two groups A and B, with 20 subjects in each group. Group A was treated with Istika Sweda, and Group B were treated with Nadi Sweda along with Rasanadi Guggulu as shamanoushadi for both groups. The effects of treatment provided to the subjects of both groups were significant. Both the treatment methods of Ishtika Sweda and Nadi Sweda showed equally significant effects in the subjects involved in a clinical study. Keywords: Vatakantaka, Calcaneal Spur, Ishtika sweda, Nadi sweda, Rasnadi guggulu.

scholarly journals Characteristics and trends of clinical studies primarily sponsored by China in WHO primary registries between 2009 and 2018: a cross-sectional survey

BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e037262 ◽  
Author(s):  
Yang Xu ◽  
Min Dong ◽  
Xuemei Liu
Keyword(s):  
Clinical Trials ◽  
Clinical Study ◽  
Depressive Disorders ◽  
Controlled Trial ◽  
Chronic Obstructive ◽  
Cumulative Number ◽  
Cross Sectional Survey ◽  
Clinical Trial Registry ◽  
Cross Sectional ◽  
Clinical Trials Registry

ObjectivesTo analyse characteristics and developmental trends of clinical study registration primarily sponsored by China’s institutions during 2009–2018.SettingRegistration information registered prior to 31 December 2018 was obtained from the International Clinical Trials Registry Platform (ICTRP) source registries, including Chinese Clinical Trial Registry, ClinicalTrials.gov, Australian New Zealand Clinical Trials Registry and International Standard Randomised Controlled Trial Number. Registration information on other ICTRP source registries was collected from the ICTRP.DesignA cross-sectional analysis was performed. The studies sponsored by mainland China’s institutions (not including institutions in Hong Kong SAR, Macau SAR or Taiwan of China) as of 31 December 2018 were filtered. For duplicate registrations, only the records with the earliest registration date were included. Global registrations were summarised for comparison.ResultsA total of 32 557 China-sponsored studies and 478 261 global studies were included. The registered China-sponsored studies, increased from a cumulative number of 1333 in 2009 to 32 557 in 2018, were less likely to have industry involvement (14% vs 30%) and more likely to be registered prospectively (63% vs 45%) than the global registrations during 2009–2018. The top three most studied health conditions were lung cancer (4.2%), diabetes (3.8%) and ischaemic heart disease (3.2%). Depression and depressive disorders and chronic obstructive pulmonary disease (COPD) each represented 1.1% of registered China-sponsored studies. Phase 2 and phase 3 trials together accounted for 30%, notably lower than the global level (53%). The registered studies responding to an individual participant data (IPD) sharing plan had increased since 2016, but the proportions of studies indicating ‘yes’ were still at a low level and accounted for 5% of the registered China-sponsored studies and global registrations.ConclusionsClinical study registration activity in China has been substantial during 2009–2018. Some diseases with a high disease burden in China (depression and depressive disorders and COPD) were underrepresented by the proportion of registered studies. The accessibility of IPD merits improvement.

scholarly journals A comparative clinical study on the cosmetic approach in Tarunyapidaka vis-a-vis Acne Vulgaris amongst female population through Shodhana Shamana and Lepa

2020 ◽  
Vol 5 (05) ◽  
pp. 104-110
Author(s):  
Sharanamma A ◽  
Prashanth A.S. ◽  
S.G. Chavan
Keyword(s):  
Clinical Study ◽  
Clinical Efficacy ◽  
Acne Vulgaris ◽  
Ayurvedic Medicine ◽  
Inclusion Criteria ◽  
Female Population ◽  
Common Skin ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Tarunyapiadaka is one of the Kshudraroga and most common skin disorders. Ayurvedic medicine plays important role in the patients who are in deep depression due to disfiguration of face and Tarunyapidaka in the field of Cosmetiology. In the present study an effort has been made to formulate an effective, economic and simple remedy to help in the total cure and preventing of Tarunyapidaka. In the present study 40 Subjects diagnosed with Tarunyapidaka w.s.r to Acne Vulgaris fulfilling the Inclusion criteria were selected for study and randomly categorized into two groups as Group A and Group B each consisting of 20 subjects from OPD and IPD of department of PG studies in Kayachikitsa department of Ayurveda Mahavidhyalaya, Hubbali have been treated with Amapachana with Guduchi Churna. In group A Sadhyosnehapana with Panchatikta Ghrita. Sarvanga Abhyanga with Elaadi Taila followed by Sarvanga Swedana. And Sneha Virechana was administered with Trivruth Lehya. After Samsarjana Krama, Navaka Kashaya given as a Shamanoushadi along with Manjista with Madhu Lepa. In Group B Sadhyosnehapana with Panchatikta Ghrita. Sarvanga Abhyanga with Elaadi Taila followed by Sarvanga Swedana and Sneha Virechana was administered with Trivruth Lehya. After Samsarjana Krama, Gopanganadi Kashaya given as a Shamanoushadi along with Manjista with Madhu Lepa for 45 days to assess the clinical efficacy of Navaka Kashaya and Gopanganadi Kashaya. Significant changes in Subjective and Objective criteria were observed.

A Comparative Clinical Study on the Management of Arshas with Haridradi Lepa and Pippalyadi Lepa.

2017 ◽  
Vol 2 (1) ◽  
Author(s):  
K. M. Siddalinga Murthy ◽  
N. B. Mashetti
Keyword(s):  
Clinical Study ◽  
Cold Water ◽  
Simple Random Sampling ◽  
Therapeutic Effects ◽  
Duration Of Treatment ◽  
External Application ◽  
Treatment Measures ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Arsha is as old mankind being an abnormal to routine life. Arsha does not cause any threat to life but troubles a lot, so it is included in one of the Astha Maharogas by Sushruta. This disease is largely confined to the Guda but also in Nasa, Netra, Karna etc. regions. Aetiological factors are vitiation of Doshas in Gudavalis, injury due to throne, stone, nail, vehicle, regular contact of cold water etc. Haemorrhoids are the varicosity of haemorrhoidal veins. Depending on the site these are 3 types viz, Internal, Externel and Intero-external Haemorrhoids. Depending upon bleeding these are 2 types which are bleeding and non bleeding piles. The presently available treatment measures are Aushadha, Shastra, Kshara and Agnikarma. Local external application is described by Sushruta, Yogaratnakara, Charaka and others. Hence a comparative clinical study is planned to evaluate the efficiency and malignant role of Haridradi Lepa and Pipplayadi Lepa in Arshas (Piles). In this study sample size of 40 patients were selected by simple random sampling, 20 in Group-A and 20 in Group-B, in Group-A, Haridradi Lepa was used, where as in Group-B Pippalyadi Lepa was used. The therapeutic effects was analyzed by using the subjective parameters viz. pain and discomfort during sitting and objective paramaters viz, size, BPR (bleeding per rectum), mucous discharge etc. The duration of treatment was 15 days and clinical assesement was done in 5 days interval. At the end of study, the Haridradi Lepa has shown significally benefical result in sustaianable manner.

Comparative Clinical Study of the Effects of Disulfiram and Calcium Carbimide. I. Side Effects

1960 ◽  
Vol 21 (4) ◽  
pp. 642-654 ◽  
Author(s):  
Juan Marconi ◽  
Guido Solari ◽  
Sergio Gaete ◽  
Luisa Piazza
Keyword(s):  
Clinical Study ◽  
Side Effects ◽  
Comparative Clinical Study

Comparative Clinical study of Jatyadi Taila and Jatyadi Ghrita in the management of Dushta Vrana

2018 ◽  
Vol 3 (3) ◽  
Author(s):  
Rajendra Joshi ◽  
N. B. Mashetti ◽  
Rakesh Kumar Gujar
Keyword(s):  
Clinical Study ◽  
Burning Sensation ◽  
Normal Process ◽  
Surgical Practice ◽  
Local Factors ◽  
Significant Difference ◽  
Comparative Clinical Study ◽  
Group A ◽  
Contaminated Wound ◽  
Group B

Dushta Vrana is a common and frequently encountered problem faced in surgical practice. The presence of Dushta Vrana worsens the condition of the patient with different complications and may become fatal. Local factors on wound like slough, infection and foreign body, affect the normal process of healing. A healthy wound in a normal body heals earlier with a minimum scar as compared to a contaminated wound. Therefore in this study all the efforts are made to make a Dushta Vrana into a Shuddha Vrana. Once the Vrana becomes Shuddha, Ropana of the Vrana will start. The objective of the study was to evaluate the clinical efficacy of Jatyadi Taila and Jatyadi Ghrita in Dushta Vrana. Clinically diagnosed 60 Patients of Dushta Vrana were randomly divided into two groups, each consisting of 30 Patients. Group A were treated with the Jatyadi Taila and Group B was treated by Jatyadi Ghrita. The results observed was based on the relief obtained on the subjective and objective parameters taken for consideration for this study viz, size of ulcer, discharge, smell, pain, burning sensation, itching and granulation were found significant (P Lass Than 0.05). On the basis of assessment criteria and overall result of treatment, the patients of Jatyadi Taila group showed better results when compared to Jatyadi Ghrita group. Even though statistically there is no much significant difference between the two groups, but by seeing the effect on individual parameters (subjective and objective) and over all response, Jatyadi Taila seems to be effective when compared to Jatyadi Ghrita. It is having more Ropana qualities when compared to Shodhana.

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