scholarly journals Modern Methods of Early Detection of Endometrial Cancer on the Example of “Pipelle” Urogenital Probe

2021 ◽  
Vol 01 (05) ◽  
Author(s):  
Nigora Ergashevna Atakhanova ◽  
Keyword(s):  
Endometrial Cancer ◽  
Early Detection ◽  
Uterine Cancer ◽  
Tumor Diseases ◽  
New Methods ◽  
Modern Methods ◽  
Prevention And Treatment

Today, at a time when cancer is developing rapidly, a number of scientific studies are being conducted worldwide in the field of early detection, prevention and treatment of the disease. A number of new methods are being recommended by experts to put into practice, which is convenient, effective, rapid, uncomplicated and painless methods of early detection of tumor diseases especially uterine cancer in women.

scholarly journals Metabolomic Biomarkers for the Detection of Obesity-Driven Endometrial Cancer

Cancers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 718
Author(s):  
Kelechi Njoku ◽  
Amy E. Campbell ◽  
Bethany Geary ◽  
Michelle L. MacKintosh ◽  
Abigail E. Derbyshire ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Early Detection ◽  
Minimally Invasive ◽  
Cancer Detection ◽  
Test Performance ◽  
Female Genital Tract ◽  
Screening Tools ◽  
Normal Endometrium ◽  
Endometrioid Endometrial Cancer ◽  
Post Menopausal

Endometrial cancer is the most common malignancy of the female genital tract and a major cause of morbidity and mortality in women. Early detection is key to ensuring good outcomes but a lack of minimally invasive screening tools is a significant barrier. Most endometrial cancers are obesity-driven and develop in the context of severe metabolomic dysfunction. Blood-derived metabolites may therefore provide clinically relevant biomarkers for endometrial cancer detection. In this study, we analysed plasma samples of women with body mass index (BMI) ≥ 30 kg/m2 and endometrioid endometrial cancer (cases, n = 67) or histologically normal endometrium (controls, n = 69), using a mass spectrometry-based metabolomics approach. Eighty percent of the samples were randomly selected to serve as a training set and the remaining 20% were used to qualify test performance. Robust predictive models (AUC > 0.9) for endometrial cancer detection based on artificial intelligence algorithms were developed and validated. Phospholipids were of significance as biomarkers of endometrial cancer, with sphingolipids (sphingomyelins) discriminatory in post-menopausal women. An algorithm combining the top ten performing metabolites showed 92.6% prediction accuracy (AUC of 0.95) for endometrial cancer detection. These results suggest that a simple blood test could enable the early detection of endometrial cancer and provide the basis for a minimally invasive screening tool for women with a BMI ≥ 30 kg/m2.

scholarly journals Integrative review of the nursing interventions used for the early detection of cervical uterine cancer

2011 ◽  
Vol 19 (2) ◽  
pp. 437-444 ◽  
Author(s):  
Camila Teixeira Moreira Vasconcelos ◽  
Marta Maria Coelho Damasceno ◽  
Francisca Elisângela Teixeira Lima ◽  
Ana Karina Bezerra Pinheiro
Keyword(s):  
Early Detection ◽  
Uterine Cancer ◽  
Nursing Interventions ◽  
Evidence Based ◽  
National Program ◽  
Cognitive Interventions ◽  
Social Interventions ◽  
Positive Effects ◽  
Effective Result ◽  
Selection Of

In a national program to combat cervical uterine cancer (CUC) four basic elements should exist: primary prevention, early detection, diagnosis/treatment and palliative care. Of these, early detection is the most effective modality. One of the purposes of Evidence-Based Practice (EBP) is to encourage the use of research results with the assistance provided, reinforcing the importance of research for clinical practice. This study aimed to evaluate the evidence available in the literature regarding effective nursing interventions for the early detection of CUC. The selection of articles was performed in the databases: Scopus, PubMed, CINAHL, Lilacs and Cochrane. The sample of this review consisted of seven articles, with evidence levels 1, 2 or 3. The behavioral, cognitive and social interventions, showed positive effects in the early detection of CUC, especially the interactive cognitive interventions. It is suggested, when appropriate, to use a combination of interventions in order to obtain a more effective result.

scholarly journals Controversies in the Management of Endometrial Carcinoma: An Update

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Mohamed K. Mehasseb ◽  
John A. Latimer
Keyword(s):  
Radiation Therapy ◽  
Endometrial Cancer ◽  
Early Detection ◽  
Endometrial Carcinoma ◽  
Genital Tract ◽  
Female Genital Tract ◽  
Developed Countries ◽  
Changing Roles ◽  
The Developed Countries ◽  
Female Genital

Endometrial carcinoma is the commonest type of female genital tract malignancy in the developed countries. Endometrial carcinoma is usually confined to the uterus at the time of diagnosis and as such usually carries an excellent prognosis with high curability. Our understanding and management of endometrial cancer have continuously developed. Current controversies focus on screening and early detection, the extent of nodal surgery, and the changing roles of radiation therapy and chemotherapy and will be discussed in this paper.

scholarly journals MODERN METHODS OF DIAGNOSIS OF POST PROSTHETIC COMPLICATIONS DURING DENTAL IMPLANTATION

2020 ◽  
Vol 74 (2) ◽  
pp. 72-76
Author(s):  
D.V. Mikhalchenko ◽  
◽  
Yu.A. Makedonova ◽  
Kh.Yu. Salyamov ◽  
◽  
...  
Keyword(s):  
Early Detection ◽  
Bone Tissue ◽  
Early Period ◽  
Cortical Plate ◽  
Frequency Of Occurrence ◽  
Timely Manner ◽  
Diagnostic Measures ◽  
Dental Implantation ◽  
Modern Methods ◽  
Prosthetic Complications

The number of dental implants performed at the dental reception is steadily increasing. Along with this increased and the frequency of occurrence postprostatectomy complications in dental implantation. One of the main tasks of a dentist is early detection of the initial signs of inflammation of the parotid tissue, leading to mucositis. If you do not act on the site of inflammation in a timely manner, the destruction of bone tissue around the implant will begin with the development of peri-implantitis. In this work, we conducted a retrospective analysis of the frequency of occurrence of mucositis and periimplantitis. An algorithm for diagnostic measures has been developed. The patients were determined by the hygienic index, the iodine number of Svrakov, the degree of bleeding, and the depth of probing of the dental sulcus. The implant stabilization was determined using amplitude-frequency analysis. A detailed periodontal screening was performed to assess the condition of the gums and identify pathological processes occurring in the tissue surrounding the implants. The condition of the cortical plate and parotid bone tissue was evaluated radiologically. The developed algorithm for diagnostic examination of patients with postprotetic complications during dental implantation helps to detect inflammation in an early period, which in turn allows to preserve the integrity of the tooth.

The Disabled Learner: Early detection and intervention (Modern approaches to the diagnosis and instruction of multi-handicapped children, vol. 8), edited by P. Satz, and J. Ross. The Netherlands: The Rotterdam University Press, 1973, 297 pp., $18.65

PEDIATRICS ◽  
1974 ◽  
Vol 53 (6) ◽  
pp. 958-958
Author(s):  
James J. A. Cavanaugh
Keyword(s):  
Early Detection ◽  
Language Development ◽  
Specific Learning Disability ◽  
Learning Disorders ◽  
Basic Information ◽  
Handicapped Children ◽  
New Methods ◽  
Development Section ◽  
The Disabled ◽  
Specific Learning

In The Disabled Learner editors Satz and Ross present a potpourri of articles previously delivered at a conference held to acquaint physicians, educators and psychologists with new basic information in the field of learning disorders and to review new methods of intervention. The book falls far short of this goal. The biology is naive, the language development section is uninformed, or at least systematically ignores a broad literature in this discipline, and the chapters that deal with specific learning disability and developmental dyslexia are unrewarding.

scholarly journals Laparoscopic management of cervical and endometrial cancer in Africa: experience of the National Hospital Centre of Pikine

2019 ◽  
Vol 8 (11) ◽  
pp. 4429
Author(s):  
Moussa Diallo ◽  
Abdoul Aziz Diouf ◽  
Aminata Niass ◽  
Astou Coly Niassy Diallo ◽  
Cyr Esperence Gombet ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Squamous Cell Carcinoma ◽  
Endometrial Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Uterine Cancer ◽  
Operating Time ◽  
National Hospital ◽  
Main Interest

Background: Laparotomy represents the standard historical surgical approach to these cancers. Process of treatment of benign adnexal pathologies to the emergence of a new pathway for the management of these cancerous pathologies.Methods: Our prospective study from December 2016 to December 2018 included 10 patients with early-stage uterine cancer and endometrial cancer confirmed by MRI. The characteristics of patients, their cancer, their intervention and morbidity were revealed.Results: Our results show that the average age of the patients was 63 years; There were 2 cases of cervical cancer and 8 cases of endometrial cancer. For cervical cancer, it was essentially squamous cell carcinoma; one patient was at stage Ia2 and the other at stage Ib1. For endometrial cancers, squamous cell carcinoma was 80%; 6 patients were in stage IB and 2 in stage IC. Of the 10 patients undergoing surgery, 9 had laparoscopic colpohysterectomy and lymphadectomy and one complementary laparoscopic lymphadenectomy. The average number of lymph nodes removed was 9 and no lymph node metastasis was found. In the immediate postoperative period, one patient had transient urinary incontinence and another had vaginal slice lymphorhea.Conclusions: The main interest of this practice is to be the least morbid possible for patients at the early stage. With our short experience, we obtained a reduction in operating time, a reduction in hospital stay, a decrease in the consumption of analgesics and antibiotics postoperatively and a reduction in per and postoperative complications.

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