scholarly journals The role of plant extract drugs in treatment of LUTS due to benign prostate enlargement. Clinical cases review

2021 ◽  
Vol 2 (5) ◽  
pp. 39-44
Author(s):  
Adel S. Al-Shukri ◽  
◽  
Stanislav V. Kostyukov ◽  
Albina V. Maksimova ◽  
◽  
...  
Keyword(s):  
Plant Extract ◽  
Individual Treatment ◽  
Prostate Hyperplasia ◽  
Prostate Enlargement ◽  
Urinary Tract Symptoms ◽  
Surgical Methods ◽  
Prostatic Enlargement ◽  
Methods Of Treatment ◽  
Clinical Cases

In this article covered in detail the problem of lower urinary tract symptoms (LUTS), due to benign prostatic enlargement. The mechanisms of etiology and pathogenesis of prostate hyperplasia are analyzed. The review is done of modern methods of treatment, such as surgical methods and conservative. Special attention is paid to plant extract drugs in therapy of LUTS. Have done the analysis of several clinical trials, they prove effectiveness and low percentage of side effects. Some clinical cases are considered, demonstrating the way of outpatient examination of patients with LUTS and how to choose the tactic of treatment witch based on anamnesis, laboratory and instrumental examination. What confirms the necessity of individual treatment for every patient.

scholarly journals THE ROLE OF ORTHODONTIC CARE IN THE COMPLEX REHABILITATION OF GLOSSECTOMY PATIENTS

2021 ◽  
Vol 21 ◽  
pp. 42-45
Author(s):  
Yu. P. Mansur ◽  
◽  
D.V. Verstakov ◽  
L.N. Scherbakov ◽  
◽  
...  
Keyword(s):  
Quality Of Life ◽  
Malignant Tumors ◽  
Tongue Cancer ◽  
Vital Functions ◽  
Surgical Methods ◽  
Jaw Abnormalities ◽  
Orthodontic Devices ◽  
Methods Of Treatment

n recent years, Russia has seen an increase in the incidence of malignant tumors of the mouth and throat, including tongue cancer. Surgical methods of treatment of cancer of such localization have a crippling character and inevitably lead to disruption of a number of vital functions, including the development of tooth-jaw deformities, which further deteriorates the quality of life of such patients. Timely prescription of orthodontic devices for prophylactic and therapeutic purposes allows to prevent the development of tooth jaw abnormalities and deformities, as well as to treat the already developed pathology.

scholarly journals Role of Trospium chloride and tamsulosin therapy for treating patients with symptoms of over-active bladder related to benign prostatic enlargement

2020 ◽  
Vol 11 (1) ◽  
pp. 650-656
Author(s):  
Falah Mahdi Ali ◽  
Hayder Mahdi Alaridy ◽  
Ahmed Ali Obaid
Keyword(s):  
Teaching Hospitals ◽  
Benign Prostatic Enlargement ◽  
Trospium Chloride ◽  
Prostate Hyperplasia ◽  
Overactive Urinary Bladder ◽  
Prostatic Enlargement ◽  
Bladder Symptoms ◽  
Benign Prostate ◽  
Over Active Bladder

To assess the benefit and safety of composite therapy (Tamsulosin and Trospium drugs) in treating benign prostatic enlargement complain, mainly overactive urinary bladder symptoms. OBJECTIVE: The study has been designed to estimate the benefit and safety of Trospium and Tamsulosin in processing of symptoms of excessive bladder and benign prostate hyperplasia (BPH). Patients and Methods: Prospective clinical trial study conducted at Al-Diwaniya teaching hospitals and private clinics from march 2016 to march 2017, to patients BPH and bothersome symptoms. 60 patients were treated with Tamsulocin and 60 patients were treated by Tamsulocin and Trospium. RESULTS: Median scores of IPSS, OABSS, and QOL proved no big difference between two study sets before staring treatment (P = 0.544), (P = 0.287) , (P = 0.668) consecutively. After one month, both treatments led to a big reduction in IPSS, OABSS median score; (P < 0.001), (P < 0.001). Following three months, both treatments resulted in significant reduction in IPSS (P < 0.001), OABSS (P < 0.001), QOL result, (P < 0.001) consecutively. Conclusion: These results suggest which treatment with Trospium and tamsulosin therapy provides benefit for men with natural - Syndrome of the acute urinary tract and benign enlarged prostate.

scholarly journals Canine benign hyperplasia prostate on male pug dog

2019 ◽  
Vol 3 (3) ◽  
pp. 49-50
Author(s):  
Zulfa Ichsanniyati R. Ciwi Fadhlillah ◽  
I Nengah Yogiswari ◽  
Siti Zaenab ◽  
Deni Noviana ◽  
Sukmasari Arifah
Keyword(s):  
Ultrasound Examination ◽  
Benign Prostate Hyperplasia ◽  
Blood Chemistry ◽  
Prostate Hyperplasia ◽  
Mild Anemia ◽  
Prostate Enlargement ◽  
Prostate Size ◽  
Abdominal Palpation ◽  
Prostatic Enlargement ◽  
Benign Prostate

An 9-years-old male pug was examined for stranguria and letargic in one week. The dog has no testicles as the owner claimed that the dog had been castrated a few years ago. Abdominal palpation shows bladder retention filled with urine but no blockage was found. Urine sedimentation contained blood and few unknown crystal. Hematology showed mild anemia and leukocytosis while blood chemistry only found mild hyperglobulinemia. Radiography showed prostate enlargement. Ultrasound examination was showing mild nephrolithiasis, cystitis and prostatic enlargement. Diagnosis of benign prostate hyperplasia is suspected but doubtful because the animal has been castrated. Differential diagnose was prostatic cysts, infection and cancer. The dog received finasteride 1 mg/kg twice a day orally for 60 days and antibiotic. Urine catheter was temporarily installed to evacuate urine twice a day. Post treatment ultrasound was performed 20 days later and showed evident involution of prostate sizes. An enlarge irregular testicle was also found in right dorsolateral of bladder. Monorchid castration was performed at 60 days of finasteride. The dog was diagnosed with monorchid induce benign prostate hyperplasia from the radiography and ultrasonography. The prostate size was reduced after finasteride administration

The role of laparoscopic ovarian electrocautery in the new millennium

1999 ◽  
Vol 7 (2) ◽  
pp. 111-129
Author(s):  
Barry W Donesky
Keyword(s):  
Ovulation Induction ◽  
Polycystic Ovary ◽  
Wedge Resection ◽  
Surgical Approaches ◽  
Ovary Syndrome ◽  
Complete Replacement ◽  
Surgical Methods ◽  
Methods Of Treatment ◽  
Anovulatory Infertility

With the introduction of bilateral ovarian wedge resection (BOWR) in 1935, Stein and Leventhal were the first to describe an effective treatment for the chronic anovulation and associated infertility resulting from what was later to become known as polycystic ovary syndrome (PCOS). Since that time, many less invasive methods of ovulation induction and enhancement have been developed. While the success of medical ovulation induction led to the almost complete replacement of BOWR by the late 1970's, the presence of a group of women who are not optimally treated by medical methods has maintained the interest in surgical approaches. Surgical and nonsurgical methods of treatment for anovulatory women have continued to be refined. This manuscript reviews this literature and attempts to provide a framework for the role that modern surgical methods of ovulation induction might play in the current scheme of treatment for anovulatory infertility in women with PCOS.

scholarly journals Endocrine disruptor bisphenol A is implicated in urinary voiding dysfunction in male mice

2018 ◽  
Vol 315 (5) ◽  
pp. F1208-F1216 ◽  
Author(s):  
Tristan M. Nicholson ◽  
Jalissa L. Nguyen ◽  
Glen E. Leverson ◽  
Julia A. Taylor ◽  
Frederick S. vom Saal ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Adult Male ◽  
Endocrine Disruptor ◽  
Voiding Dysfunction ◽  
Animal Experiments ◽  
Bladder Volume ◽  
Male Mice ◽  
Prostate Enlargement ◽  
Urinary Tract Symptoms

Estrogens, acting synergistically with androgens, are known from animal experiments to be important in lower urinary tract symptoms (LUTS) and benign prostate enlargement. Human exposure to environmental estrogens occurs throughout the life span, but the urologic health risks in men are largely unknown. Bisphenol A (BPA) is an endocrine disruptor implicated in male urogenital malformations. Given the role of estrogens in male LUTS, we studied the effects of BPA administered in combination with testosterone (T) on the urinary voiding behavior of adult male mice. Adult male mice underwent subcutaneous implantation with slow-release pellets of 25 mg BPA or 2.5 mg estradiol-17β (E2), plus 25 mg T, and were compared with untreated (UNT) mice that underwent sham surgery. We studied urinary voiding behavior noninvasively for 1 mo before treatment and for 4 mo after treatment. After euthanasia, we evaluated bladder volume and mass. Mice treated with T+BPA had increased bladder volume ( P < 0.05) and mass ( P < 0.01) compared with UNT mice. After 4 mo of treatment with T+BPA, three of five mice developed voiding dysfunction in the form of droplet voiding or an intermediate pattern of voiding different from both UNT and T+E2-treated mice. Treatment of male mice with BPA or estradiol induces voiding dysfunction that manifests at later time points, implicating the endocrine disruptor, BPA, as a contributor to male LUTS.

scholarly journals Endocrinology of the Aging Prostate: Current Concepts

2021 ◽  
Vol 12 ◽  
Author(s):  
Rossella Cannarella ◽  
Rosita A. Condorelli ◽  
Federica Barbagallo ◽  
Sandro La Vignera ◽  
Aldo E. Calogero
Keyword(s):  
Type Ii Diabetes Mellitus ◽  
Hormonal Changes ◽  
Prostate Hyperplasia ◽  
Urinary Tract Symptoms ◽  
Numerous Data ◽  
The Impact ◽  
Ovarian Syndrome

Benign prostate hyperplasia (BPH), one of the most common diseases in older men, adversely affects quality-of-life due to the presence of low urinary tract symptoms (LUTS). Numerous data support the presence of an association between BPH-related LUTS (BPH-LUTS) and metabolic syndrome (MetS). Whether hormonal changes occurring in MetS play a role in the pathogenesis of BPH-LUTS is a debated issue. Therefore, this article aimed to systematically review the impact of hormonal changes that occur during aging on the prostate, including the role of sex hormones, insulin-like growth factor 1, thyroid hormones, and insulin. The possible explanatory mechanisms of the association between BPH-LUTS and MetS are also discussed. In particular, the presence of a male polycystic ovarian syndrome (PCOS)-equivalent may represent a possible hypothesis to support this link. Male PCOS-equivalent has been defined as an endocrine syndrome with a metabolic background, which predisposes to the development of type II diabetes mellitus, cardiovascular diseases, prostate cancer, BPH and prostatitis in old age. Its early identification would help prevent the onset of these long-term complications.

Outcome of complete macular rupture (two clinical cases)

2021 ◽  
pp. 114-116
Author(s):  
S.I. Makogon ◽  
◽  
E.N. Kuznetsova ◽  
Y.A. Bryukhanova ◽  
◽  
...  
Keyword(s):  
Visual Acuity ◽  
Surgical Treatment ◽  
Key Words ◽  
Visual Functions ◽  
Optical Media ◽  
Surgical Methods ◽  
Modern Methods ◽  
Methods Of Treatment ◽  
Management Tactics ◽  
Clinical Cases

Purpose. To present the course of a complete macular rupture, depending on the management tactics. Material and methods. On the example of two clinical cases, the outcome of a complete macular rupture is presented: without surgical treatment and as a result of surgery. Results. Surgical methods of treatment made it possible to obtain high visual functions in the patient - visual acuity up to 0.9. Conclusions. Modern methods of surgical treatment of MR provide restoration of the structure of the outer layers of the retina and high visual functions, provided that the optical media of the eye are transparent. Key words: macular rupture, surgical treatment of macular rupture, course of macular rupture without treatment.

The history of the background and modification of surgical methods for treatment of benign prostate hyperplasia

2021 ◽  
pp. 61-69
Author(s):  
Mark Albertovich Volodin ◽  
Maya Andreevna Kuzmina ◽  
Daria Dmitrievna Vasina ◽  
Evgeny Nikolaevich Bolgov ◽  
Vladimir Aleksandrovich Perchatkin
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Surgical Techniques ◽  
Prostatic Hyperplasia ◽  
Prostate Hyperplasia ◽  
Surgical Interventions ◽  
Literary Sources ◽  
Surgical Methods ◽  
History Of ◽  
Methods Of Treatment

The article presented an overview of literary sources, which include a description of various surgical techniques for the treatment of benign prostatic hyperplasia in different historical periods. The assessment of the disadvantages and advantages of various surgical methods for the treatment of benign prostatic hyperplasia has been made. Modification and improvement of surgical interventions, changes in methods and approaches to surgical treatment of benign prostatic hyperplasia made the surgeon’s work more accessible and of high quality. The development of surgical methods of treatment has made it possible to increase the efficiency of surgical interventions, which, in turn, has a positive effect on the quality of life of urological patients.

scholarly journals Anoctamin 1 (TMEM16A) is essential for testosterone-induced prostate hyperplasia

2015 ◽  
Vol 112 (31) ◽  
pp. 9722-9727 ◽  
Author(s):  
Joo Young Cha ◽  
Jungwon Wee ◽  
Jooyoung Jung ◽  
Yongwoo Jang ◽  
Byeongjun Lee ◽  
...  
Keyword(s):  
Prostatic Hyperplasia ◽  
Elderly Men ◽  
Anoctamin 1 ◽  
Prostate Hyperplasia ◽  
Prostate Epithelial Cells ◽  
Prostate Enlargement ◽  
Urinary Tract Symptoms ◽  
Interfering Rna ◽  
Lower Urinary

Benign prostatic hyperplasia (BPH) is characterized by an enlargement of the prostate, causing lower urinary tract symptoms in elderly men worldwide. However, the molecular mechanism underlying the pathogenesis of BPH is unclear. Anoctamin1 (ANO1) encodes a Ca2+-activated chloride channel (CaCC) that mediates various physiological functions. Here, we demonstrate that it is essential for testosterone-induced BPH. ANO1 was highly amplified in dihydrotestosterone (DHT)-treated prostate epithelial cells, whereas the selective knockdown of ANO1 inhibited DHT-induced cell proliferation. Three androgen-response elements were found in the ANO1 promoter region, which is relevant for the DHT-dependent induction of ANO1. Administration of the ANO1 blocker or Ano1 small interfering RNA, inhibited prostate enlargement and reduced histological abnormalities in vivo. We therefore concluded that ANO1 is essential for the development of prostate hyperplasia and is a potential target for the treatment of BPH.

scholarly journals Thulium Laser Enucleation of the Prostate (ThuLEP) as a Technique for Treatment of BPH: Evaluation of a Six-Year Experience at a Single Institution

2018 ◽  
Vol 1 (2) ◽  
pp. e10-e14 ◽  
Author(s):  
Mahmood Vazirian-Zadeh ◽  
Jane Anderson ◽  
Ravine Gill ◽  
Islam Noaman ◽  
Katie Lee ◽  
...  
Keyword(s):  
Urinary Flow ◽  
The Novel ◽  
Thulium Laser ◽  
Urinary Tract Symptoms ◽  
Prostatic Enlargement ◽  
Laser Enucleation ◽  
First Time ◽  
Postoperative Haemoglobin ◽  
Maximum Urinary Flow

Background and objective Transurethral resection of the prostate (TURP) has been the undisputed reference standard for elderly men with lower urinary tract symptoms (LUTS) caused by benign prostatic enlargement (BPE). However, morbidity after TURP remains significant, with increased risks of bleeding and TUR syndrome. In recent years, there has been a gradual increase in the role of laser technology for the treatment of symptomatic BPE. The aim of our study was to evaluate the efficacy and safety of the novel technique Thulim laser enucleation of prostate (ThuLEP) developed for the first time in 2009 by Imkamp et al. in treating symptomatic BPE. Materials and methods Analysis of the data from electronic records, case notes, clinic letters all the patients who had undergone ThuLEP using a 70 W thulium laser (Revolix) for symptomatic outflow obstruction over a 6-year period was done. We looked at the pre-procedure PSA, maximum urinary flow rate (Qmax), Post void residual (PVR) and haemoglobin, comparing it with the postoperative haemoglobin. Results 222 patients underwent ThuLEP procedure performed by 2 surgeons. We found a 159 % improvement in Q max, a 61 % improvement in PVR. No mortalities occurred and only 1 patient required post operative blood transfusion. ThuLEP represents a safe, effective surgical option in patients with symptomatic BPH with relatively little complications, producing significant improvements in both Qmax and PVR. Key words LUTS, BPE, Enucleation, TUR Syndrome, Qmax

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