scholarly journals Assessment of the diagnostic significance of modern biomarkers and hemodynamic alterations in workers of vibration-hazardous occupations

2021 ◽  
Vol 65 (4) ◽  
pp. 379-383
Author(s):  
Andrey V. Melentev ◽  
Oleg A. Oshkoderov

Introduction. One of the most significant tasks in modern labor medicine is to reduce the indicators of early disability in persons in contact with harmful and dangerous factors of the production environment. The issue of finding markers of early preclinical manifestations of vibrational disease and establishing comorbid conditions that are prognostically unfavorable for the course of the underlying occupational disease remains relevant. The purpose of the study is assessment of diagnostic significance of current neurospecific biomarkers and hemodynamic changes in workers of the profession related to vibration. Material and methods. The results of two studies were the basis for this work. The first, aimed at determining the concentration of neurospecific markers in the blood of miners, includes 154 working vibration hazardous professions. At the same time, groups were identified depending on the type of exposure to vibration: total (69 workers), local (24 workers) and combined general and local (61 miners) and control group of workers not in contact with vibration (49 people). The second study was performed to assess the change in hemodynamic parameters among 216 industrial workers, of which 114 people were in contact with vibration generating equipment, and 102 workers were included in the control group. Results. Data from the first study showed an increase in the titer of neuron-specific indicators, mainly protein S100B, depending on the type of exposure vibration and its seniority dose. The second study results indicated an increase in systolic blood pressure and total peripheral vascular resistance in miners under exposure to vibration factor. Conclusion. The results of both studies suggest that hemodynamic disorders and changes in the performance of neuro specific proteins may be interconnected. It seems advisable to continue the study in workers in vibrant occupations with comorbid pathology.

Author(s):  
JAGADEESWARI J ◽  
KALABARATHI S ◽  
MANGALAGOWRI P

 Objectives: The present aims to assess the level of urinary incontinence in experimental and control group, to assess the effectiveness of vaginal cone therapy on urinary incontinence in experimental group and control group and to associate the post-test level of urinary incontinence with the selected demographic variables among women in the experimental group. Methods: A quantitative quasi-experimental research design was conducted among 60 women with urinary incontinence. Convenience sampling technique was used. Semi-structured interview method was used to collect the demographical data and level of urinary incontinence among women was assessed by urinary incontinence diagnosis questionnaire. Results: Among 60 samples in experimental group 26 women had a moderate level of urinary incontinence, and 4 women had slight urinary incontinence whereas in control group 24 women had moderate level of urinary incontinence and 6 women had slight urinary incontinence. The study results show significant improvement in level of urinary incontinence among experimental group than the control group after the intervention at the level of p<0.05. This reveals that vaginal cone therapy is highly significant in the experimental group because pelvic muscle strength had improved and allows the patient to increase the physiological consciousness and promotes the muscle tone after the use of a vaginal cone. Conclusion: This study proves that vaginal cone therapy is the effective non-pharmacological method, cost-effective method and had no side effects which can be used to treat female urinary incontinence.


2004 ◽  
Vol 4 (4) ◽  
pp. 28-31
Author(s):  
Sabaheta Hasić ◽  
Emina Kiseljaković ◽  
Radivoj Jadrić ◽  
Belma Zečević ◽  
Nešina Avdagić ◽  
...  

Long term stress exposure results in somatisation symptoms appearance. Cardiovascular, respiratory, gastrointestinal and muscle-bone symptoms arise because of intensified activity of autonomic nervous system caused by chronic stress. The aim of the study was to examine the relationship between long term war stress exposure and appearance of somatisation. 40 students of health-care faculties in Sarajevo, of both sexes, were included in investigation and divided in two groups-somatisation and control. Somatisation group subjects (N=20) lived in B&H under war conditions, from 1992-1995. Control subjects (N=20) spent the same period outside B&H. For evaluation of somatisation symptoms we used SCL-90-R test. The obtained data were statistically evaluated using Student’s t-test and χ2 test. Confidence level was set at ρ < 0,05. Our results showed statistically significant difference in somatisation level between somatisation and control subjects group. Different intensity of appearance of certain symptoms in male and female was established. The score of somatisation dimension between somatisation and control group showed statistically significant level (p < 0,0001). Study results confirmed correlation of chronic stress exposure (living in war environment) and somatisation symptom appearance. Individual organic systems had various level of symptom expression. The influence of sex on intensity of individual symptoms of somatisation is possible.


2020 ◽  
Vol 6 (2) ◽  
pp. 36-41
Author(s):  
I. V. Litvinenko ◽  
A. A. Yurin

Purpose. To evaluate therapeutic options of rhythmic transcranial magnetic stimulation (rTMS) in the treatment of consequences of minor traumatic brain injury.Materials and methods. A neuropsychological examination using standard scales for assessing cognitive functions, as well as the Beck depression inventory, the Spielberger State-Trait Anxiety Inventory, and the MFI-20 multidimensional fatigue inventory was performed on patients with traumatic brain injury (TBI) and complaints of decreased memory, attention, general weakness and fatigue. Patients were split into two groups. Active group (24 patients) received rhythmic TMS besides standard treatment (neurometabolic, nootropic) while control group (23 patients) received only standard therapy. After the treatment course, the reassessment of neuropsychological examination with the following statistic processing was performed.Study results. Comparison of treatment results in the active and control groups showed the highest efficacy of rTMS in the treatment of depression (p=0,016), anxiety (p=0,001) and in fatigue lowering (p=0,017) in patients with consequences of minor TBI.Conclusion. The data obtained from the study point the high efficacy of treatment of consequences of minor TBI by means of rTMS that displays in lowering of fatigue, anxiety, and depression severity when using.


Author(s):  
Jignya Vinodbhai Asari ◽  
Anjali Pushkar Tiwari

Introduction: Pregnant woman experience various physical, emotional, and hormonal changes that may cause anxiety. The anxiety and worries can be decreased by sharing information about the developing child, like foetal body movement. Aim: To assess effect of Foetal Movement Counting (FMC) on prenatal attachment and maternal worries among primigravida mothers. Materials and Methods: A longitudinal study was carried out among primigravida mothers of selected Hospitals of Central Gujarat using proforma of Cranley’s maternal foetal attachment scale and Cambridge worry scale. The study was conducted from March 2019 to July 2020. Eighty participants were recruited by convenient sampling 40 in each study group and control group. The study group were provided with foetal movement chart and the participants were asked to record foetal movements for seven consecutive days, twice a day for 20 minutes. Post assessment of prenatal attachment and maternal worries was done using tools of data collection for both study and control group. Chi- square test was used to test the significance (p-value <0.05). Results: The study results revealed that in study group mean score for prenatal attachment was 79.43 at the start and improved to 101.25 (p-value <0.001) after seven days of FMC. In control group, the mean score for prenatal attachment did not show significant difference pre-test and post-test (74.20 vs 74.85, p-value=0.077). In study group, the mean Cambridge worry scale score was 36.55 which came down to 20.28 (p-value <0.001) after seven days, while in control group it was 41.38 at the beginning and 41.30 after seven days (p-value=0.998). Conclusion: Foetal Movement Counting was found to improve maternal foetal attachment and reduce maternal worries. FMC can be routinely and effectively promoted among the pregnant population to help them achieve a positive pregnancy experience and outcome.


2019 ◽  
Vol 19 (3) ◽  
pp. 125-130
Author(s):  
I Novikov ◽  
V Novikov ◽  
M Novikova

Aim. The article deals with a possible correction of physical development and physical fitness in boys with hearing impairments with the help of sports gymnastics. Materials and methods. Boys aged 7–9 years were divided into two groups – experimental and control – 25 persons in each group. In the control group, the lessons were conducted following a standard program. In the experimental group, the lessons followed the program of sports gymnastics. In both groups, the training course lasted six months. Testing was conducted at the beginning and the end of the study. Results. After the experiment, the results of the experimental group exceed those of the control group. Conclusion. Regular lessons made according to a sports gymnastics program allow improving physical development and physical fitness in boys with hearing impairments aged 7–9 years.


10.2196/22500 ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. e22500
Author(s):  
Jean-Francois Pelletier ◽  
Janie Houle ◽  
Marie-Hélène Goulet ◽  
Robert-Paul Juster ◽  
Charles-Édouard Giguère ◽  
...  

Background In times of pandemics, social distancing, isolation, and quarantine have precipitated depression, anxiety, and substance misuse. Scientific literature suggests that patients living with mental health problems or illnesses (MHPIs) who interact with peer support workers (PSWs) experience not only the empathy and connectedness that comes from similar life experiences but also feel hope in the possibility of recovery. So far, it is the effect of mental health teams or programs with PSWs that has been evaluated. Objective This paper presents the protocol for a web-based intervention facilitated by PSWs. The five principal research questions are whether this intervention will have an impact in terms of (Q1) personal-civic recovery and (Q2) clinical recovery, (Q3) how these recovery potentials can be impacted by the COVID-19 pandemic, (Q4) how the lived experience of persons in recovery can be mobilized to cope with such a situation, and (Q5) how sex and gender considerations can be taken into account for the pairing of PSWs with service users beyond considerations based solely on psychiatric diagnoses or specific MHPIs. This will help us assess the impact of PSWs in this setting. Methods PSWs will lead a typical informal peer support group within the larger context of online peer support groups, focusing on personal-civic recovery. They will be scripted with a fixed, predetermined duration (a series of 10 weekly 90-minute online workshops). There will be 2 experimental subgroups—patients diagnosed with (1) psychotic disorders (n=10) and (2) anxiety or mood disorders (n=10)—compared to a control group (n=10). Random assignment to the intervention and control arms will be conducted using a 2:1 ratio. Several instruments will be used to assess clinical recovery (eg, the Recovery Assessment Scale, the Citizenship Measure questionnaire). The COVID-19 Stress Scales will be used to assess effects in terms of clinical recovery and stress- or anxiety-related responses to COVID-19. Changes will be compared between groups from baseline to endpoint in the intervention and control groups using the Student paired sample t test. Results This pilot study was funded in March 2020. The protocol was approved on June 16, 2020, by the Research Ethics Committees of the Montreal Mental Health University Institute. Recruitment took place during the months of July and August, and results are expected in December 2020. Conclusions Study results will provide reliable evidence on the effectiveness of a web-based intervention provided by PSWs. The investigators, alongside key decision makers and patient partners, will ensure knowledge translation throughout, and our massive open online course (MOOC), The Fundamentals of Recovery, will be updated with the evidence and new knowledge generated by this feasibility study. Trial Registration ClinicalTrials.gov NCT04445324; https://clinicaltrials.gov/ct2/show/NCT04445324 International Registered Report Identifier (IRRID) PRR1-10.2196/22500


2014 ◽  
Vol 9 (5) ◽  
pp. 870-878
Author(s):  
Tuswadi ◽  
◽  
Takehiro Hayashi ◽  

This research investigated the educational benefits of improving students’ performance associated with two types of teaching used in integrated disaster prevention lessons. Our research, experimental in nature, applied a pretest/posttest control group design. The research sample consisted of 89 students in grade 5 at two primary schools near the Merapi volcano, which is under the Sleman regency of Yogyakarta Special Region Province, Indonesia. Students were classified into experimental and control groups. Using the same lesson content, delivered by one of our researchers, the experimental group was taught through discussions and the control group was taught through lectures. Findings showed that lectures improved two viewpoints in students’ knowledge – one regarding appropriate action taken while indoors during a big earthquake and the other about consequences of a big earthquake regarding a residential fire. Student viewpoints regarding their awareness of living in a disaster-prone area were also found to have improved through the use of lectures. Discussions were found to be helpful in improving only one viewpoint of students’ knowledge about appropriate actions while indoors during a big earthquake. Study results suggest that efforts should be made to develop effective education in volcanic disaster at school focusing on changes in students’ knowledge, attitude, and behavior.


2020 ◽  
Vol 17 (2) ◽  
Author(s):  
Alaa K. Al-asadi ◽  
May F. Al-Habib ◽  
Ula M. Al-Kawaz ◽  
Mohammad Oda Selman ◽  
Imad Matloub Al-Ani

INTRODUCTION: This study explored the adaptive changes in pancreatic islets by assessing the maternal pancreatic β-cell mass (PβCM), islets size, number, shape, distribution and vascularity using the anti-GAD65 Ab as a marker in pregnant mice. MATERIALS AND METHODS: Fourty female Swiss-Webster mice were randomly divided into two age matched groups of 20 animals each, pregnant and control (non-pregnant) groups. The pregnant mice were sacrificed at Day 19 of gestation and the control group was sacrificed 19 days after observation in the same environmental conditions. Specimens of pancreata were fixed in 10% formal-saline, and processed for light microscopy. Paraffin sections were stained with chromogen DAB. Image scope (APERIO) with Image J software was used for morphometric study. RESULTS: Islets cells showed specific reaction with GAD65 Ab. There was an increase in the cellularity and vascularity of the PβCM. A significant increase in the islets area of the pregnant group ranging between 32-723 µm2 in comparison with the control group that ranged between 5–210 µm2 , the islet size and numbers also increased; there were numerous newly formed islets and coalescence of adjacent islets, positive reactivity of β-cells toward antiGAD65 during pregnancy, the mean of positive granulation in PβCM in pregnant group was 8273.5±SE 831.35 while in control group was 34±SE 0.2. CONCLUSION: The changes for alteration in PβCM such as increase in cells number, size, positive anti-GAD65 reactivity and their vascularity during pregnancy is related to the adaptation for hormonal and nutritional demands of both foetus and mother.


2020 ◽  
Vol 11 (SPL4) ◽  
pp. 43-49
Author(s):  
Deepika D ◽  
Thenmozhi P ◽  
KalaBarathi S

Acute pain is an often unpleasant experience during the postoperative period after abdominal surgery causes diminish in physical functioning, which evokes stress. Hence, the study aimed to determine the effectiveness of Progressive Muscle Relaxation combined with music on the reduction of postoperative pain and stress among patients who have undergone abdominal surgery. The quasi-experimental research design was chosen to conduct the study with 40 samples matched with inclusion criteria. Samples were allocated into the experimental group (n=20) and control group (n=20) by convenience sampling technique. A pre-test was done by using a numerical pain scale and the perceived stress scale for both experimental and control group. The experimental group received progressive muscle relaxation for 10 minutes, followed by theme music for 5 minutes twice a day for three consecutive postoperative days. Control group received the routine care of the hospital. Posttest was done at the end of the third day for both experimental and control group using the same tool. There was a highly statistically significant (p<0.001) reduction in the level of pain and stress after Progressive Muscle Relaxation combined with music at the level of was observed within the experimental group and also found significant (p<0.001) difference between the experimental and control group by unpaired t-test. The study results concluded that progressive muscle relaxation combined with music is useful in the reduction of pain and stress. It is also a simple, cost-effective, and non-pharmacological method that can be used to complement pharmacological management during the postoperative period.


Author(s):  
Mesfer Saud Mubarak Al- Hersh

The study aimed to reveal the effectiveness of using educational activities based on entertainment in development listening and speaking skills in the Arabic language course (Loghati) of the third- grade students. To achieve this، the researcher followed the semi-experimental approach based on creating two groups: experimental group and control group. He also prepared a number of activities that contain entertainment with selecting number of listening and speaking skills that are related to the course goals and content. In addition to that, he designed listening test، speaking situations and note card for speaking skills. The study sample consisted of (28) students divided into two groups: an experimental group of (14) students and a control group of (14) students. The researcher pre-tested the students in listening and speaking. The results showed no statistically significant differences between the two groups. After that، the experimental group studied using entertainment-based activities، while the control group studied in the usual way. At the end of the application the two groups were post-tested in listening and speaking، the study results were as follows: There were statistically significant differences between the average grades of the experimental and control groups in the listening post-test in favor of the experimental group. There were statistically significant differences between the average grades of the experimental and control groups in the speaking post-test in favor of the experimental group. Considering the findings of the study، several recommendations were presented: Add educational activities based on entertainment in the Arabic language course (Loghati); to assist in the development of listening and speaking skills. Ask Arabic teachers' assessments to focus on teachers' attention in developing listening and speaking skills and giving them as much importance as other language skills.


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