scholarly journals A Review Article on Phytochemical Investigation and Pharmacological Activity of Various Parts of Dalbergia sissoo

2021 ◽  
Vol 69 (1) ◽  
Author(s):  
Pooja Soni ◽  
Prashant Kumar
Keyword(s):  
Pharmacological Activity ◽  
Anthelmintic Activity ◽  
Pharmacological Action ◽  
Review Article ◽  
Antidiabetic Activity ◽  
Antiulcer Activity ◽  
Dalbergia Sissoo ◽  
Antipyretic Activity ◽  
Phytochemical Investigation ◽  
Coagulant Activity

Current study discussing the ethnobotanical importance of the different part of the plant Dalbergia sissoo its pharmacological activity and various formulation. Nature is like a treasure of medicine. From last thousands year nature give us several type of medicines which we use for the treatment of different type of diseases and valetudinarism. Dalbergia sissoo is one the most crucial/significant plant with full of medicinal attribute. Dalbergia sissoo (Fabaceae) has reported to possess different type pharmacological activity such as antinociceptive activity, anti-coagulant activity, antibacterial activity, anti-inflammatory activity, memory enhancing activity, antiulcer activity, nephro-protective activity, anti-spermatogenic activity, analgesic activity, antipyretic activity, antitermitic activity, antilithiatic activity, antidiabetic activity, anthelmintic activity, immunomodulation activity and so on. This study divulging the medicinal important and all pharmacological action of the different part of the plant Dalbergia sissoo.

An ayurvedic tablet formulation for ulcer protection

2020 ◽  
Vol 10 (4) ◽  
pp. 35-38
Author(s):  
Shiva Kumar K ◽  
Purushothaman M ◽  
Soujanya H ◽  
Jagadeeshwari S
Keyword(s):  
Pharmacological Activity ◽  
The Body ◽  
Gastric Ulcers ◽  
Antiulcer Activity ◽  
Herbal Drugs ◽  
Human Beings ◽  
Synthetic Drugs ◽  
Scientific Investigations ◽  
System A ◽  
The World

Gastric ulcers or the peptic ulcer is the primary disease that affects the gastrointestinal system. A large extent of the population in the world are suffering from the disease, and the age group of people those who suffer from ulcers are 20-55years. Herbs are known to the human beings that are useful in the treatment of diseases, and there are a lot of scientific investigations that prove the pharmacological activity of herbal drugs. Practitioners have been using the herbal material to treat the ulcers successfully, and the same had been reported scientifically. Numerous publications have been made that proves the antiulcer activity of the plants around the world. The tablets were investigated for the antiulcer activity in two doses 200 and 400mg/kg in albino Wistar rats in the artificial ulcer those are induced by the ethanol. The prepared tablets showed a better activity compared to the standard synthetic drug and the marketed ayurvedic formulation. The tablets showed a dose-dependent activity in ulcer prevention and treatment. Many synthetic drugs are available for the ulcer treatment, and the drugs pose the other problems in the body by showing the side effects and some other reactions. This limits the use of synthetic drugs to treat ulcers effectively. Herbs are known to the human beings that are useful in the treatment of diseases, and there are a lot of scientific investigations that prove the pharmacological activity of herbal drugs.

scholarly journals Antidiabetic and antiulcerative potential of Garcinia lanceifolia Roxb. bark

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Nilutpal Sharma Bora ◽  
Partha Sarathi Bairy ◽  
Abdus Salam ◽  
Bibhuti Bhusan Kakoti
Keyword(s):  
Body Weight ◽  
Serum Levels ◽  
Northeast India ◽  
Scientific Data ◽  
Antidiabetic Activity ◽  
Histological Evaluation ◽  
Albino Rats ◽  
Antiulcer Activity ◽  
Dose Dependent

Abstract Background Garcinia lanceifolia Roxb. has been used by many ethnic communities of Northeast India to mitigate various disorders like dyspepsia, ulcers, diabetes, etc. However, a robust scientific study on its antidiabetic and antiulcer potential is unavailable till date. The aim of this present study is to scientifically validate if the antidiabetic and antiulcer effects reported by the ethnic tribes of Assam has any scientific value or not. The effects were tested in adult Wistar albino rats using approved animal models for preclinical testing of pharmacological activities. Results The hydroalcoholic extract of the bark of Garcinia lanceifolia Roxb. was prepared and its LD50 was calculated. The LD50 was determined to be greater than 5000 mg/kg body weight. The extract at doses of 250 mg/kg body weight and 500 mg/kg body weight was found to exhibit a very potent dose-dependent antidiabetic activity. The results were backed by a battery of test including analysis of serum levels of blood glucose, lipid profiles, in vivo antioxidant enzymes, and histopathological studies. Evidence of dose-dependent antiulcer activity of the extract was backed by robust scientific data. It was found that HAEGL induced a significant dose-dependent increase in the ulcer index in both alcohol-induced and acetic acid-induced ulcer models, which was evident from the macroscopic observation of the inner lining of the gastric mucosa and the histological evaluation of the extracted stomach. Conclusion The results suggested that the bark of Garcinia lanceifolia (Roxb.) has significant antidiabetic and antiulcer potential. Further studies with respect to the development herbal dosage forms and its safety evaluation are required.

Phytochemical Investigation of the Leaves of Tetracera scandens Linn. and In Vitro Antidiabetic Activity of Hypoletin

2014 ◽  
pp. 591-608 ◽  
Author(s):  
Qamar Uddin Ahmed ◽  
Abdulrashid Umar ◽  
Muhammad Taher ◽  
Deny Susanti ◽  
Mohamed Zaffar Ali Mohamed Amiroudine ◽  
...  
Keyword(s):  
Antidiabetic Activity ◽  
Phytochemical Investigation

scholarly journals HEPATOPROTECTIVE, ANTIDIABETIC, AND ANTIPYRETIC ACTIVITY STUDIES OF SIDDHA FORMULATION – NILAVEMBU KUDINEER

2020 ◽  
pp. 115-119
Author(s):  
KASIRAJAN N ◽  
MAHESHWARI B ◽  
SUBASHCHANDRAN G ◽  
MAANICKHA CHELVI KS
Keyword(s):  
In Vitro Study ◽  
Treated Group ◽  
Hepatoprotective Effect ◽  
Antidiabetic Activity ◽  
Control Group ◽  
Cellulose Solution ◽  
Virus Infections ◽  
Citrate Buffer ◽  
Antipyretic Activity

Objective: Traditional medicines like Siddha System of Medicine are one of the most primitive medical system. It plays a major role in treating ailments of humankind. Nowadays, this system flourished throughout India using Nilavembu kudineer (NVK) as a drug to treat in various outbreaks such as dengue, Chikungunya, and other related virus infections. As per literature, NVK indicated many types of fever and various diseases. This study emphasizes on antipyretic, antidiabetic, and hepato protective activities of NVK by In vitro study methods. Methods: Hepatoprotective effect of NVK on Carbon tetrachloride-induced hepatotoxicity in the rat in five groups, antipyretic activity tested by subcutaneous injection of 10 ml/kg of 15% w/v yeast suspended in 0.5% w/v carboxymethyl cellulose solution for elevation of body temperature of rats in 6 groups. Antidiabetic activity done by administration of streptozotocin dissolved in citrate buffer (pH 4.5) and nicotinamide, intraperitoneal injection of 60 mg/kg streptozotocin, 15 min after the i.p administration of 120 mg/kg of nicotinamide in non-insulin-dependent diabetes, in six groups. Results: The hepatoprotective effect having the significance of one way ANOVA followed by Dunnett’s (n=6); nsp>0.05, *p<0.05, **p<0.01, and ***p<0.001, calculated by comparing treated groups tumor with the control group. Antidiabetic activity having the significance of Dunnett’s ***p<0.001, **p<0.01, and *p<0.05 calculated by comparing the treated group with the control group and antipyretic activity results in Dunnett’s *p<0.05 calculated by comparing the treated group with the control group were considered to be significant. Conclusion: The study shows that NVK having the potency of hepatoprotective and capability of diabetes in vitro studies. This study also revealed the potency of antipyretic activity against yeast.

scholarly journals A Review on Phytochemical Constituents and Pharmacological Activities of Ricinus communis L. Plant

2017 ◽  
Vol 9 (4) ◽  
Author(s):  
Manoj Kumar
Keyword(s):  
Castor Bean ◽  
Ricinus Communis ◽  
The Body ◽  
Bean Plant ◽  
Antidiabetic Activity ◽  
Immunomodulatory Activity ◽  
Antiulcer Activity ◽  
Pharmacological Activities ◽  
Ricinus Communis L ◽  
Phytochemical Constituents

The medicinal plants have a vital role to take care of the healthy human life. The large family Euphorbiaceae contains nearly about 300 genera and 7,500 species. Amongst all, Ricinus communis L. or castor bean plant has high traditional and medicinal values towards a disease free community. The castor bean plant is effective as antifertility activity, antiimplantation activity, antinociceptive activity, anticancer activity, antioxidant activity, immunomodulatory activity, hepatoprotective activity, antidiabetic activity, antiulcer activity, antimicrobial activity, insecticidal activity, molluscicidal and larvicidal activity, bone regeneration activity, central analgesic activity, antihistaminic activity, antiasthmatic activity, cytotoxic activity, lipolytic activity, antiinflammatory activity, and wound healing activity. In addition, the constituents present in this plant are beneficial for the purpose of contraception, leaving no detrimental effects on the body. The objective of the present review focuses on the phytochemical constituents, pharmacological activities and future perspectives of the R. communis L. plant.

Phytochemical Analysis and Anthelmintic Activity of Salsola imbricata

2019 ◽  
Vol 41 (1) ◽  
pp. 198-198
Author(s):  
Muhammad Ajaib Muhammad Ajaib ◽  
Saleha Farooq Saleha Farooq ◽  
Khalid Mohammed Khan Khalid Mohammed Khan ◽  
Shahnaz Perveen and Shazia Shah Shahnaz Perveen and Shazia Shah
Keyword(s):  
Cardiac Glycosides ◽  
Anthelmintic Activity ◽  
Chloroform Extract ◽  
Reducing Sugar ◽  
Minimum Time ◽  
Bark Extract ◽  
Phytochemical Analysis ◽  
Fruit Extract ◽  
Phytochemical Investigation

Phytochemical investigation and anthelmintic activity of Salsola imbricata Forssk was carried out. Phytochemical analysis showed the presence of anthraquinones, reducing sugar, tannins, saponins, flavonoids, alkaloids and cardiac glycosides. Analysis of anthelmintic activity exhibited that bark extract of S. imbricata is more potent than fruit extract. Minimum time for paralysis and death of worms (9 and#177; 0.6 and 13 and#177; 0.2 min.) was taken by chloroform extract of bark at concentration of 100 mg/mL whereas fruit extract of chloroform was taken minimum time for paralysis and death of worms (10 and#177; 1.1 and 16 and#177; 0.1min.) at concentration of 100 mg/mL.

scholarly journals Strophanthus hispidus –continued: Pharmacological Action

1890 ◽  
Vol 16 ◽  
pp. 743-748
Author(s):  
Thomas R. Fraser
Keyword(s):  
Pharmacological Activity ◽  
Subcutaneous Administration ◽  
Pharmacological Action ◽  
Active Principle

(Abstract.)Strophanthus extract and Strophanthin are substances of great pharmacological activity, as, by subcutaneous administration, Strophanthin produces death in average-sized frogs with a dose of . of a grain, and in rabbits weighing about 3 lbs. with a dose of of a grain. The kind of action is the same with both substances, and therefore Strophanthin may properly be regarded as the active principle of Strophanthus hispidus.

scholarly journals Analytical Strategies to Analyze the Oxidation Products of Phytosterols, and Formulation-Based Approaches to Reduce Their Generation

Pharmaceutics ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 268
Author(s):  
George Gachumi ◽  
Asmita Poudel ◽  
Kishor M. Wasan ◽  
Anas El-Aneed
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Liquid Chromatography ◽  
Pharmacological Activity ◽  
Review Article ◽  
Oxidation Products ◽  
Separation Technique ◽  
Cholesterol Lowering ◽  
Phytosterol Oxidation Products ◽  
Analytical Strategies

Phytosterols are a class of lipid molecules present in plants that are structurally similar to cholesterol and have been widely utilized as cholesterol-lowering agents. However, the susceptibility of phytosterols to oxidation has led to concerns regarding their safety and tolerability. Phytosterol oxidation products (POPs) present in a variety of enriched and non-enriched foods can show pro-atherogenic and pro-inflammatory properties. Therefore, it is crucial to screen and analyze various phytosterol-containing products for the presence of POPs and ultimately design or modify phytosterols in such a way that prevents the generation of POPs and yet maintains their pharmacological activity. The main approaches for the analysis of POPs include the use of mass spectrometry (MS) linked to a suitable separation technique, notably gas chromatography (GC). However, liquid chromatography (LC)-MS has the potential to simplify the analysis due to the elimination of any derivatization step, usually required for GC-MS. To reduce the transformation of phytosterols to their oxidized counterparts, formulation strategies can theoretically be adopted, including the use of microemulsions, microcapsules, micelles, nanoparticles, and liposomes. In addition, co-formulation with antioxidants, such as tocopherols, may prove useful in substantially preventing POP generation. The main objectives of this review article are to evaluate the various analytical strategies that have been adopted for analyzing them. In addition, formulation approaches that can prevent the generation of these oxidation products are proposed.

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