scholarly journals A Study of Microbiological Profile in patients with Acute Pyelonephritis in a Tertiary Care Hospital, Nandyal

2021 ◽  
Vol 8 (3) ◽  
pp. 61-69
Author(s):  
Nagarjuna Reddy Pogula Nagarjuna Reddy
Keyword(s):  
Escherichia Coli ◽  
Acute Pyelonephritis ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Medical College ◽  
Microbiological Profile ◽  
Study Population ◽  
The Mean ◽  
Culture Positive

Background : Acute pyelonephritis is a bacterial infection that affects the renal parenchyma that can be life-threatening and often leads to renal scarring. It usually ascended from the lower urinary tract, and also reach the kidney via the bloodstream. Early diagnosis and management of acute pyelonephritis have a better impact on patient outcomes. Acute pyelonephritis is one of the severe conditions with high mortality and morbidity. It represents the most severe form of urinary tract infection. Acute pyelonephritis is the most common cause of communityonset bacteremia in elderly patients1. Aim: To study the microbiological profile in patients with acute pyelonephritis admitted in a tertiary care hospital. Materials and Methods: A Hospital-based Prospective study was conducted in the Department of Medicine, Santhiram medical college & general hospital for a 2 year period.Universal Sampling Technique was used for the selection of study subjects.The study population included patients admitted with fever, flank pain, and positive urine or blood cultures in the department of general medicine in Santhiram medical college and general hospital.The final sample size was 50 subjects. Results: In the present study, 50 participants were selected as the study population. The mean age of the study population was 57.48 ± 11.21. The majority of participants (70%) were distributed in a 50 to 69-year age group. Majority of participants were females (60%) and males (40%).In the current study among participants, in the current study, urine culture was positive in 29 patients (58%) of the study population. In 29(58%) of the subjects who had a culture-positive infection, the most predominant infectious agent in the present study group was Escherichia. coli and was reported in 22 (44%) of the study subjects. Other causative organisms include, Klebsiella pneumonia was reported in 2(4%) subjects. Candida albicans, Citrobacter, Enterococcus faecalis, and Pseudomonas were isolated in 1 (2%) subject each. One subject had a dual infection with Escherichia coli and Candida.In current study, among the 29 culture isolates, none of them were resistant to Cefperazone plus Sulbactum or Piperacillin plus tazobactam. The highest proportion of resistance was reported for Ampicillin as 82.1% of isolates were resistant. Levofloxacin resistance was found in 67.9% of isolates. Gentamicin and Amikacin resistance was found 17.86% and 3.6% of the isolates. Nitrofurantoin resistance was found in 2 (7.1%) of isolates. Conclusion: The mean age of the study population was 57.480 ± 11.2072 years in the study population, and there was a slight female preponderance in the occurrence of APN.The majority of participants (78%) were distributed ina 50 to 69-year age group.Diabetes, hypertension, ureteric calculus, and past history of UTI were the common risk factors identified in the study population.In.More than half (58%) of the study population had a culture-positiveinfection.TheThe most common organism isolated in the study population was E.Coli, responsible for 44% of the cases. None of them were resistant to Cefoperazone plus Sulbactum or Piperacillin plus tazobactam. The other antimicrobials, which have not shown any resistance, were Meropenem and Colistin.The highest proportion of resistance was reported for Ampicillin in 82.1%, followed by Levofloxacin in 67.9% of isolates. ICU admission rate was higher in culture-positive cases (63.6%), as compared to culture-negative cases (36.4%)None of the study subjects had hospital mortality

scholarly journals Socio-demographic Characteristics of Vesico-vaginal fistula (VVF) patients attended at a tertiary Care Hospital in Bangladesh

2020 ◽  
Vol 6 (2) ◽  
pp. 114-117
Author(s):  
Shimul Akter ◽  
Naznin Rashid Shewly ◽  
Kashefa Khatun ◽  
Rokshana Parvin Nupur ◽  
Kamrun Nahar ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Demographic Characteristics ◽  
Medical College Hospital ◽  
Care Hospital ◽  
Vaginal Fistula ◽  
College Hospital ◽  
Medical College ◽  
The Mean ◽  
Vesico Vaginal Fistula

Background: Vesico-vaginal fistula can occur in different women with varied socio-economic condition. Objectives: The purpose of the present study was to see the socio-demographic characteristics of vesico-vaginal fistula (VVF) patients attended at a tertiary care hospital in Bangladesh. Methodology: This cross-sectional study was carried out from July 2013 to December 2013 for a period of 6 months in the National Fistula Centre in the Department of Obstetrics & Gynaecology at Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh. All patients who underwent surgical repair for iatrogenic VVF in National Fistula Centre of the department of Obstetrics and Gynaecology of Dhaka Medical College Hospital were included in this study. Patients who got themselves admitted to Obstetrics & Gynaecology department of DMCH with the complaints of fistula. The entire selected patients were interviewed for detailed socio-demographic characteristics. Result: A total number of 51 cases of VVF were recruited for this study. The mean age was 46.02 (±SD 6.104) years. Most of the respondents were illiterate (55.0%) and one-third patients had primary level education. The number of highly educated patients was scarce (12.0%). It was evident that average age at marriage of the patients was 15.8(±4.74) years. Some females were forced to accept marriage at the age of 10 years. The mean interval between initiation of menstruation and the marriage was only 4.72 years. Mothers were on an average 17.48 years old at the time of first delivery. Conclusion: In conclusion middle age illiterate women are most commonly suffering from VVF. Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 114-117

scholarly journals Over prescription of Proton Pump Inhibitors on discharge of Medical Inpatients

2017 ◽  
Vol 18 (1) ◽  
pp. 27-29 ◽  
Author(s):  
Sarmistha Biswas ◽  
ABM Abu Sufian ◽  
Prodip Kumar Sarkar ◽  
Mostofa Kamal Chowdhury ◽  
Joybaer Anam Chowdhury ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Safety And Health ◽  
Medical Inpatients ◽  
Study Population ◽  
Potential Risks ◽  
The Mean

Background: Proton pump inhibitors (PPIs) are the drugs used to treat and prevent acid peptic conditions. Their efficacy and safety profile has led to injudicious prescription of these drugs exposing patients to various potential risks and increased healthcare expenditure.Methodology: A retrospective observational study was done from 10th January to 24th January, 2015 in Medicine Indoor in a tertiary care hospital to determine the trend of prescribing PPIs on discharge of Medical inpatients.Result: We found 117 patients were discharged in the study period; 83 were male and 34 were female. Among them 102 (87.17%) were prescribed PPIs on their discharge. Mean age was 44.79 years. Among the study population only 29 patients (28.5%) truly needed PPIs during their discharge. The mean duration of prescribed PPIs was 28 days.Conclusion: Amore rational prescription of PPI during discharge will have better impact on patient safety and health care expenditure.J MEDICINE January 2017; 18 (1) : 27-29

scholarly journals Study of drug utilization pattern in gynecology department of tertiary care hospital of Rajasthan, India

2018 ◽  
Vol 7 (7) ◽  
pp. 2650
Author(s):  
Neelam Sharma ◽  
Anshul Jhanwar
Keyword(s):  
Drug Utilization ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Utilization Pattern ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
Medical College ◽  
Related Information ◽  
The Mean

Background: With increasing awareness the flow of patients visiting gynecology outpatient department has increased. Drugs used in gynecology are one of the most selling drugs in India, however they are least studied with respect to drug utilization. Thus, present study was undertaken to analyse drug utilization pattern of Gynecology OPD in a tertiary care hospital.Methods: A retrospective, cross sectional, observational study of prescriptions in Gynecology OPD of Jhalawar medical college, Jhalawar. Data was obtained from medical record database of patients that attended Gynecology OPD from October 2017 to March 2018 over period of six months. Prescription records of patients were screened as per inclusion and exclusion criteria and 300 prescriptions were randomly selected. Patient related, and drug related information was collected on a customized data collection sheet.Results: The mean age of patients was 20.5±8.65 years and common age of presentation was >18-30 years. In infective cases, PID (40.6%) was common, and in non-infective cases, menorrhagia (23.8%) was common. The average number of drugs per prescription was 5.2. In drug category, minerals (46.4%) were most commonly prescribed, followed by antimicrobials (27.6%), and NSAIDs (20.1%). Polypharmacy was observed in 100% of the prescriptions.Conclusions: In the present study all of the drugs prescribed were generic which were from the essential medical list of NLEM and WHO. This study revealed deviation from rational prescribing by the prescribers because average number of drugs per prescription was significantly higher than that recommended by WHO.

Disease severity and colonic involvement of Ulcerative colitis in a tertiary care hospital of Rajshahi Medical College

2018 ◽  
Vol 28 (2) ◽  
pp. 58-60
Author(s):  
PM Basak ◽  
MMR Khan ◽  
MK Rahman ◽  
HS Das ◽  
Md Nure Alam Siddiqui ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Disease Severity ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Mucosal Inflammation ◽  
North American Population ◽  
Care Hospital ◽  
Medical College ◽  
Colonic Involvement ◽  
Study Population

Ulcerative colitis is an idiopathic inflammatory bowel disease characterized by continuous mucosal inflammation that starts in the rectum and extends proximally. Ulcerative colitis is considered frequent in majority of European and North American population and exceptional in most of the developing Asian countries. The present study was designed to estimate the disease severity and colonic involvement of ulcerative colitis in a tertiary care hospital of Rajshahi Medical College. The study population includes of 60 ulcerative colitis patients. Patients were categorized on the basis of disease severity ; moderate : 34, and severe: 26 and involvement of colon: 28 (46.40%) pancolitis, 20 (33.96%) left sided colitis and had 12 (19.61%) proctosigmoiditis.TAJ 2015; 28(2): 58-60

scholarly journals Prescription Patterns of Antimicrobial Drugs in Hospitalized Patients in Tertiary Care Hospital of Kathmandu

2016 ◽  
Vol 15 (1) ◽  
pp. 52-60
Author(s):  
Binod Raut ◽  
Anjan Khadka ◽  
Rabindra Nath Borah
Keyword(s):  
Tertiary Care Hospital ◽  
Respiratory Infections ◽  
Tertiary Care ◽  
Care Hospital ◽  
Antimicrobial Drugs ◽  
Prescription Pattern ◽  
Key Factor ◽  
Duration Of Hospitalization ◽  
Study Population ◽  
The Mean

Introduction: Antimicrobial drugs are one of the most commonly prescribed drugs in hospital. Overuse and irrational use of antimicrobials is a key factor behind rapidly spreading antimicrobial resistance in microorganisms. Use of irrational and unnecessary antimicrobials remains common in the developing countries.  This study was conducted to analyze the prescription pattern of antimicrobials in the department of internal medicine of tertiary care hospital. Methods: Antimicrobials are among the most commonly prescribed drugs in hospital. Overuse and irrational use of antimicrobials is a key factor behind rapidly spreading antimicrobial resistance in microorganisms. Use of irrational and unnecessary antimicrobials remains common in the developing countries.  This study was conducted to analyze the prescription pattern of antimicrobials in the department of internal medicine of tertiary care hospital. Results: The mean duration of hospitalization among the study population was 5 days. Of the 460 medicines prescribed, mostly indicated for respiratory infections, and the most common antibiotic was from the group cephalosporin 209 (69.7 %).  55 % of prescriptions include only one drug, 39 % with two drugs and 6% with three or more than three drugs. Conclusion: The mean duration of hospitalization among the study population was 5 days. Of the 460 medicines prescribed, mostly indicated for respiratory infections, and the most common antibiotic was from the group cephalosporin 209 (69.7 %). 55 % of prescriptions include only one drug, 39 % with two drugs and 6% with three or more than three drugs.

scholarly journals Demographic profile and pathway to care in patients with schizophrenia in a tertiary care hospital from western Nepal

2017 ◽  
Vol 4 (1) ◽  
pp. 27-29
Author(s):  
M. Belbase ◽  
J. Adhikari ◽  
T.A. Khan ◽  
R.K. Jalan
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Descriptive Study ◽  
Care Hospital ◽  
Age Group ◽  
Medical College ◽  
Study Population ◽  
First Contact ◽  
Pathway To Care ◽  
Severe Mental Health Problem

Introduction: Schizophrenia is one of the severe mental health problem and its guarded treatment response and association with as the stigma makes it a chronic debilitating personal, family and social problem of all the psychiatric illness. Timely Identification and management of this condition is important as early diagnosis and management gives better treatment response.Methods: This is a descriptive study done in patients attending psychiatry OPD of Nepalgunj Medical College, Kohalpur for 12 months from June 2013 to May 2014.Results: Out of the 86 study subjects (n=86), males were 54 in number followed by 32 females. The most common age group was 21-40 years representing 46(53.4%), followed by 41-60 years 24(28%), <20 years 12(13.9%) and >60 years 4(4.7%). The most common first contact of the patient with schizophrenia was with faith healers 54 (62.8%) followed by consultation with psychiatrist 18(20.9%). Among the study population, 38(44.2%) visited to the psychiatrist after >41 weeks of the beginning of the illness followed by 34(39.5%) visited in <10 weeks of the beginning of the schizophrenia.Conclusions: Faith healers were the most common first contact person for the patients with schizophrenia followed by psychiatrist . Most of the schizophrenia patients come to psychiatrist after 40 weeks of their illness.

scholarly journals Trend of Sensitivity Pattern of Uropathogenic Escherichia coli: Five Year Experience at a Tertiary Care Hospital in Dhaka

2013 ◽  
Vol 5 (2) ◽  
pp. 103-105
Author(s):  
Most. Fahmida Begum ◽  
Abu Syed Md. Mosaddek ◽  
Kawser Perveen ◽  
Rezina Karim ◽  
Nurun Nahar Begum
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Bacterial Infections ◽  
Tertiary Care ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College ◽  
Sensitivity Pattern ◽  
Study Population ◽  
Tract Infections

Background: Urinary tract infections are among the most common bacterial infections caused by pathogens with a decreasing susceptibility to several classes of antimicrobials.Objective: The purpose of the present study was to see the trend of sensitivity pattern of Escherichia coli (E. coli) isolated from the urinary tract patients.Methodology: This retrospective study was conducted at Uttara Adhunik Medical College Hospital, Dhaka from 2008 to 2012 for a period of 5(five) years. All patients were within ages 1 month to 80 years, comprising of both male and female, either out or in patients were included as study population. Urine sample was collected and Escherichia coli was isolated and identified as well as the antimicrobial susceptibility patterns was determined.Results: A total number of 16,666 urine samples were collected. No significant changes of susceptibility pattern of Escherichia coli was found to ciprofloxacin, cephradine, ceftriaxone, levofloxacin,  nalidixic  acid,  imipenem  and  meropenem;  however,  significant  change  was  detected  to amoxicillin, amoxiclav, cefixime, trimethoprim-sulfamethoxazole, amikacin, ceftazidime and mecillinam between 2008 and 2012.Conclusion: Trend of sensitivity pattern of Escherichia coli is changing to few important antibiotics.DOI: http://dx.doi.org/10.3329/jssmc.v5i2.20766J Shaheed Suhrawardy Med Coll, 2013;5(2):103-105

scholarly journals Epidemiological characteristics of COVID-19 patients of tertiary care hospital of Western Rajasthan

2020 ◽  
Vol 7 (11) ◽  
pp. 4473
Author(s):  
Mathur S. L. ◽  
Agrawal Harish ◽  
Hakim Afzal ◽  
Jain Arvind ◽  
Kishoria Naveen ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Age Groups ◽  
Care Hospital ◽  
Preventative Measures ◽  
Asymptomatic Patients ◽  
Study Population ◽  
The Mean ◽  
Epidemiological Characteristics

Background: COVID – 19 is a pandemic that originated from Wuhan, China in the end of 2019. The objective of the present study is to report the epidemiological and clinical features of COVID-19 patients of tertiary care hospital of Western Rajasthan, India.Methods: A total of 1632 cases of COVID-19 were investigated. The patients tested positive by RT-PCR assay were included in the study. The data was obtained from medical record forms of the patients.Results: Out of total patients, 63.42% patients were male and 81.06% of patients were below age of 50 years. The mean of age was 34.93 ±17.61 years and median of age was 32 years. Asymptomatic patients or patients with mild symptoms constituted 66.66% of the study population and 35% of patients had comorbidities. The major comorbidities included diabetes mellitus (2.81%), hypertension (1.59%) and pulmonary diseases (1.04%). Total 40 deaths occurred so the overall CFR was 2.45%. Among the 40 deaths, the mean of age was 57.57±15.67 years. Patients over 50 years of age had the highest CFR among the age groups (18.93%). The CFR for males was 2.34% and for females 2.68%. A total of 14 (35.00%) of patients had multiple comorbidities.Conclusions: The findings of our study emphasize the significant impact of old age and multiple comorbidities on the risk of mortality among COVID-19 patients. It is suggested to take adequate preventative measures more seriously in elderly patients. Also regarding medical care, it is vital to pay special attention to elderly patients with comorbidities. 

scholarly journals Gender-wise Comparative Assessment of Lifestyle Patterns and Well-being Status among Healthcare Employees at a Tertiary Care Hospital

2021 ◽  
Author(s):  
Vanajakshamma Velam ◽  
Vyshnavi Kancherla ◽  
Latheef Kasala ◽  
Anusha Kancherla ◽  
Mounica Reddy Pillaram
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Well Being ◽  
Care Hospital ◽  
Cross Sectional ◽  
Significant Difference ◽  
Female Employees ◽  
The Mean ◽  
Lifestyle Patterns ◽  
Comprehensive Study

Abstract Background This study was an attempt to assess and compare the gender-wise lifestyle patterns and well-being status among the employees of a tertiary care teaching hospital. Material and Methods This is a cross-sectional, questionnaire-based study conducted at a tertiary care hospital between May and August 2019. A total of 777 employees belonging to both genders (male and female) and working at different professional levels were assessed. All the enrolled employees were subjected to a comprehensive study tool consisting of various dimensions of their health, which included physical, mental, social, spiritual and intellectual health dimensions. Results Among the participants, 327 (42.1%) were male and 450 (57.9%) were female. There was no significant difference in the mean age of male (37.91 ± 7.52) and female (36.85 ± 8.16) employees (p = 0.07). A significantly higher proportion of diabetes and hypertension were seen in male employees (9.8% and 14.4%, respectively) than in female (5.6% and 6.2% respectively). The overall well-being was better in male employees than in females and was statistically significant (p < 0.0001). We found that male employees had statistically significant better well-being in terms of physical, mental and social health whereas female employees had intellectual health. Conclusion The overall well-being in healthcare staff was good at our tertiary care hospital, and the outstanding/good well-being rate was higher in male employees than in female employees. Female employees experienced risks with regard to their physical health.

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