Formulation and Invitro evaluation of immediate release tablets containing febuxostat
2021 ◽
pp. 93-101
Keyword(s):
In the present research work, Febuxostat Immediate Release Tablet was prepared by direct compression method using varying concentrations of Lycoat, Crospovidone& Croscarmellose sodium as disintegrants. The formulations prepared were evaluated for precompression& post-compression parameters. From the drug excipient compatibility studies, we observe that there are no interactions between the pure drug (Febuxostat) and optimized formulation (Febuxostat+ excipients) which indicates there are no physical changes. Post compression parameters were found to be within the limits. Among the formulation prepared the tablet containing 12mg of CCS shows 98.13% of the drug release within 45 min & follows first-order kinetics.
2021 ◽
pp. 267-272
2017 ◽
Vol 10
(3)
◽
pp. 227
2018 ◽
Vol 10
(1)
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pp. 31-38
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2018 ◽
Vol 10
(8)
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pp. 67
2019 ◽
pp. 202-211
2019 ◽
pp. 210-216
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Keyword(s):
2014 ◽
Vol 50
(4)
◽
pp. 943-953
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