scholarly journals Corneal Physiology and Responses to Cross-Linking and Intracorneal Rings in Keratoconus

ABSTRACT Keratoconus is a noninflammatory, usually, bilateral progressive disease. It is a pathology characterized by a progressive thinning and ectasia of the stroma that results in cone-shaped cornea. In advanced keratoconus with corneal opacities, keratoplasty, can be the only surgical alternative for a long time. Recently, new treatment alternatives were developed in keratoconus treatment, such as intracorneal ring segments and corneal cross- linking. Intracorneal ring segment acts as spacer elements between the bundles of corneal lamellae producing a shortening of the central arc length. Corneal cross-linking treatment increases the stiffness of the cornea. Several studies reported that collagen cross-linking can delay or stop keratoconus progression and produce better quality of vision. How to cite this article Kiliç A. Corneal Physiology and Responses to Cross-Linking and Intracorneal Rings in Keratoconus. Int J Keratoco Ectatic Corneal Dis 2012;1(1):1-6.

2021 ◽  
pp. 112067212110464
Author(s):  
Luca Buzzonetti ◽  
Gianni Petrocelli ◽  
Sergio Petroni ◽  
Paola Valente ◽  
Giancarlo Iarossi

Purpose: To evaluate an original approach for treating corneal ectasia and irregular astigmatism secondary to penetrating trauma in a pediatric patient. Case report: An 11 year old patient had a penetrating trauma in right eye when he was two and the refractive error was +1.50 diopters sphere −6.00 diopters cylinder axis 95°. To correct irregular astigmatism, the patient underwent simultaneous transepithelial topographic-guided laser Central Corneal Remodeling (CCR) and Corneal Cross-linking (CXL) in the attempt to regularize corneal ectasia and to improve the quality of vision. Uncorrected and Corrected Distance Visual Acuity were measured using Efficacy and Safety indexes; objective and subjective qualities of vision were evaluated using respectively corneal morphological irregularity index and National Eye Institute Visual Function questionnaires. Conclusions: Twelve month follow up suggests that simultaneous CCR and CXL could be effective to improve the quality of vision and to halt the progression of post-traumatic ectasia in pediatric patients.


2017 ◽  
Vol 1 ◽  
pp. maapoc.0000014
Author(s):  
Chris Curtis

Introduction Head and neck cancer is a life-changing disease affecting all aspects in the life of a patient; eating, swallowing, talking, and socializing become very hard to deal with and comprehensive support is essential, regardless of the person's gender, age, social status, or background. The aim of this article is to describe the journey of a patient from a clinical and personal perspective, while discussing the importance of timely access to the most appropriate treatment based on outcome and on the patient's quality of life. Case presentation The journey of a head and neck cancer patient is illustrated from his own perspective. The clinical case also highlights a few key issues on medicine access. First, it has been a long time since any new treatment or drugs have been available to treat head and neck cancer patients, although the scenario might change drastically due to the introduction of immunotherapy. Second, it is unusual that even the most caring health care professional would consider a treatment that is not licensed in their country, even if it would have made a significantly positive difference to the patient's quality of life. Conclusions The increasing patient and health care professional's awareness of a solution to their problem with the use of unlicensed treatment, and the decreasing burden linked to identifying and sourcing unlicensed treatment, should help to optimize the management of these patients and significantly impact the outcome and their quality of life.


Author(s):  
John H. Luft

With information processing devices such as radio telescopes, microscopes or hi-fi systems, the quality of the output often is limited by distortion or noise introduced at the input stage of the device. This analogy can be extended usefully to specimen preparation for the electron microscope; fixation, which initiates the processing sequence, is the single most important step and, unfortunately, is the least well understood. Although there is an abundance of fixation mixtures recommended in the light microscopy literature, osmium tetroxide and glutaraldehyde are favored for electron microscopy. These fixatives react vigorously with proteins at the molecular level. There is clear evidence for the cross-linking of proteins both by osmium tetroxide and glutaraldehyde and cross-linking may be a necessary if not sufficient condition to define fixatives as a class.


2020 ◽  
Vol 21 (1) ◽  
pp. 102-117
Author(s):  
Novia Zalmita ◽  
Muhajirah Muhajirah ◽  
Abdul Wahab Abdi

One that influences human resource indicators is education. The teacher is a profession as a job of academic specialization in a relatively long time in college. Understanding related to teacher competence is very important to have by a prospective teacher because it can affect the quality of performance as a professional teacher. The teacher's competence is known as pedagogic, professional, social and personality competencies. The issue in this study is how the competency of the teacher of the Department of Geography Education FKIP Unsyiah as a prospective teacher of geography? The purpose of this study was to determine the competence of teachers in the Department of Geography Education FKIP Unsyiah as prospective geography teachers. Quantitative description approach is used in this study to find answers to the issue. The population in this study were students of the Department of Geography Education FKIP Unsyiah class of 2015 and 2016 who had been declared to have passed the Micro Teaching and Magang Kependidikan 3 course totaling 50 people. Because the population is small and can be reached, the determination of the sample using total sampling techniques so that the sample in this study is the whole population. Data collection is done by distributing test questions to respondents. The data was analyzed using the descriptive statistics percentage formula. The results of the study indicate that the level of teacher competence of Geography Education Department students as prospective teachers is in the moderate category, namely as many as 22 respondents (44%). A total of 12 respondents (24%) were in the high category, 15 respondents (30%) were in the low category and 1 respondent (2%) were in the very low category.


The Eye ◽  
2020 ◽  
Vol 22 (130) ◽  
pp. 36-43
Author(s):  
Gulnara Andrienko

Corneal topography is the main method for assessing the regularity of the surface of the cornea. Corneal irregularity leads to a deterioration in its refractive properties and a decrease in the quality of vision. Learning the basics of corneal topography will help determine the choice of a color map for a specific situation, as well as understand and analyze the data associated with these maps. This article describes the main types of topographic maps, various patterns of corneal shape in normal and pathological conditions and how to use the data obtained to design and fit contact lenses. Despite the fact that images may vary depending on topographers used, the information presented in this article is universal.


1991 ◽  
Vol 223 ◽  
Author(s):  
Hans P. Zappe ◽  
Gudrun Kaufel

ABSTRACTThe effect of numerous plasma reative ion etch and physical milling processes on the electrical behavior of GaAs bulk substrates has been investigated by means of electric microwave absorption. It was seen that plasma treatments at quite low energies may significantly affect the electrical quality of the etched semiconductor. Predominantly physical plasma etchants (Ar) were seen to create significant damage at very low energies. Chemical processes (involving Cl or F), while somewhat less pernicious, also gave rise to electrical substrate damage, the effect greater for hydrogenic ambients. Whereas rapid thermal anneal treatments tend to worsen the electrical integrity, some substrates respond positively to long-time high temperature anneal steps.


2020 ◽  
Vol 10 (2) ◽  
pp. 175
Author(s):  
Nomensen Freddy Siahaan

After a long time was not heard to the public area, lately death penalty toward the criminal cases that classified as extraordinary crime are appear. The author discovers electronic article about the execution of the death penalty which is the prosecutor prepares to execute death penalty toward the drugs dealer. The president of Republic of Indonesia stated that it is necessary to give a deterrent effect to the convicted  criminal and keep the morality of Indonesian teenagers. According to my opinion, the author argues that it will be better and wiser if we discuss about renovating all of the Penitentiary in Indonesia than debating whether death penalty could be done in Indonesia or not, because it will be displeasure many parties, death penalty infringed the human rights of the convicted criminals and cause psychological burden to them, families, the executor of the death penalty, and other parties. Because if we have to improve the quality of the Penitentiary, if the function of Penitentiary for fostering moralily has been optimal or properly enough to the convicted criminals, Indonesia will be no longer need the death penalty option as sanction to the convicted crimanals including for the extraordinary crime (especially for drugs trafficking in our country). Penitentiary is one of the public services which aims for fostering the people that initially have bad habits (commited to the crime), so that they will have the awareness to change their bad attitude into the be better ones, will not harm others, and positively contributed to the society. Already Penitentiary’s conditions should be designed in such a way and as good as possible, so that the inmates feels like at their own home (like having a second home after his own home), and feel humaner to spend their days in the Penitentiary. The author believes that if the Penitentiary has been improved and optimized its function well, then the real purpose of Penitentiary will definitely achieved. As stated in Law Number 12 Year 1995 regarding to Penitentiary Article 2 which states "sanction system are organized in order to fostering the convicted criminals in order to be the real man, aware of their fault, improve themselves, and not to repeat the criminal act so that they can be friendly received by the community, can actively participated in the development of our country, and can socialize themselves as good citizen."Article 3 on this regulation also intensifies the function of Penitentiary "the function of Penitentiary is to prepare convicted criminals to be able to properly integrated to the society, so they can be accepted again as members of the public who are free and responsible ones." 


2019 ◽  
Vol 21 (2) ◽  
pp. 564-580
Author(s):  
Eloiza Rocha Queiroz ◽  
José Falcão Sobrinho

A região Nordeste do Brasil vem sendo alvo de medidas do Estado a mais de um século, na tentativa de solucionar o problema da falta de água em época de secas. O Estado do Ceará, por sua vez, apresenta boa parte de seu território inserido no semiárido brasileiro, uma região caracterizada pelo clima seco, com poucas chuvas e elevada evapotranspiração. A problemática da água existe há bastante tempo, principalmente o acesso em quantidade e qualidade suficientes para atender a população. O presente trabalho tem como tema central a questão dos recursos hídricos, com enfoque no abastecimento humano do município de Cariré, localizado na região noroeste do Ceará. Nosso objetivo consiste em apresentar um panorama de como atualmente a população carireense tem acesso à água potável. A metodologia adotada constitui-se em duas etapas: na primeira, realizamos levantamento de material bibliográfico e a segunda diz respeito a parte prática realizada em saídas a campo. Segundo a ONU, a água é um bem comum e que deve ser de acesso a todos, é um direito humano. Nesta perspectiva, o gerenciamento adequado dos recursos hídricos é essencial para a manutenção da qualidade de vida. Palavras-chave: Recursos Hídricos; Abastecimento Humano; Cariré-Ce. ABSTRACTThe pnortheast region from Brazil has been subject of measures for more than a century in attempts to solve the problems lack of water in dry season. The state of Ceará has a good part of its territorial inserted in Brazilian semiarid, a region characterized by dry climate, short rains and high evapotranspiration. The water issue has existed for a long time, mainly in a sufficient access of quantity and quality to serve the population. Then, this article has as a central theme the water resources focusing on water supply of the Cariré localized at Northeast region from Ceará. Therefore the purpose of the paper is to present a study about how the Carire’s population has had access to potable water currently. The methodology adopted to this research consists of two stages: Firstly it was carried out a survey of bibliographical material and secondly it concerned the practical part carried out in the field trips. In accordance to United nations, water is a commom good and it has to be available to everyone, it is a human rights. In that sense, the proper management of water resources is essential to keep the quality of life.Key-words: Human supply; Water resources; Cariré – Ce. RÉSUMÉLa région du nord-est du Brésil est la cible de mesures prises par l’État depuis plus d’un siècle pour tenter de résoudre le problème de la pénurie d’eau en saison sèche. L’État du Ceará, en revanche, présente une bonne partie de son territoire inséré dans le semi-aride brésilien, région caractérisée par un climat sec, avec peu de pluies et une forte évapotranspiration. Le problème de l'eau existe depuis longtemps, principalement l'accès en quantité et qualité suffisantes pour satisfaire la population. Le travail actuel a pour thème central la question des ressources en eau, en mettant l'accent sur l'approvisionnement humain de la municipalité de Cariré, située dans la région nord-ouest du Ceará. Notre objectif est de présenter un aperçu de la façon dont la population carioca a actuellement accès à l’eau potable. La méthodologie adoptée comporte deux étapes: dans le premier, nous procédons à une enquête sur le matériel bibliographique et le second à la partie pratique réalisée lors des visites sur le terrain. Selon l'ONU, l'eau est un bien commun et doit être accessible à tous, c'est un droit humain. Dans cette perspective, la gestion adéquate des ressources en eau est essentielle au maintien de la qualité de la vie.Mots-clés: Ressources en eau; Approvisionnement humain; Cariré-Ce.


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