scholarly journals PROGRESSION OF INFLAMMATORY PROCESSES IN PATIENTS AFTER IM NAILING USING BIOINERT AND BIODEGRADABLE IMPLANTS BASED ON MC-10 MAGNESIUM ALLOY

Author(s):  
E. V. Yatsun ◽  
G. O. Prozorova ◽  
V. M. Chorny ◽  
M. L. Golovakha ◽  
D. V. Ivchenko

Summary. Modern medicine widely uses artificial materials to replace damaged tissues and organs. Biodegradable implants should be gradually replaced with living tissue and stay functioning within a specified period, don’t have any negative impact on surrounding tissues and a human body in general. Clinical studies of biochemical values specifying the intensity of inflammatory response to IM nailing with biodegradable implants are of clinical and scientific interest. Task of the study: to substantiate of the use of implants made of biodegradable magnesium alloy MS-10 in the dynamic IM nailing for diaphyseal fractures of the tibia. Materials and methods. The study involved 34 patients with diaphyseal tibial fractures, which resembled surgical treatment (IM nailing). Cannulated intramedullary titanium nails served as a blocking pin. The treatment included closed reposition followed with IM nailing of a tibia. To lock the nail, a screw made of magnesium alloy MS-10 was inserted in a static (round) hole in 16 patients. In 18 patients, a screw made of titanium was inserted into a static hole. The both groups passed blood sampling for studies, before and after the surgery, 2 and 4 weeks, 2 and 4 months after surgery. Biochemical blood tests were to determine the concentration of fibrinogen-monomer complexes in the blood plasma (β-naphthol test). Results. The study of the activity of AST and ALT found it lower (19 and 29%) in patients with biodegradable screws, compared to the group of patients with IM nailing locked with bioinert screws. The situation was similar with ESR, fibrinogen B and total bilirubin in the blood of patients in both groups. Conclusions. The study convincingly proves the expediency of the use of biodegradable material (magnesium alloy MS-10) to produce implants for the IM nailing for the patients with long bones’ fractures.

Author(s):  
Ye.V. Yatsun ◽  
D.V. Ivchenko ◽  
M.L. Holovakha

Summary. The efficiency of using the dynamic blocking intramedullary osteosynthesis (BIOS) technique for tibial fractures with the use of biodegradable implants based on the MS-10 magnesium alloy was determined. Objective: to approve the technique and to study the effectiveness of dynamic intramedullary osteosynthesis of diaphyseal fractures of the tibia using locking screws made of the biodegradable magnesium alloy MS-10. Materials and Methods. The study was carried out in the Department of Traumatology of the Municipal Non-Profit Enterprise “City Hospital of Emergency and Ambulance” of Zaporizhzhia City Council in Zaporizhzhia on 15 patients with diaphyseal fractures of the tibia, who underwent BIOS. Cannulated intramedullary titanium rods were used as a fixator. In the proximal section, a screw made of titanium alloy was introduced into a dynamic hole; a screw made of a biodegradable magnesium alloy MC-10 was inserted into a static hole. In the postoperative period, the patients underwent a course of complex rehabilitation measures. X-ray control was performed on day 1, at week 4, week 8, and week 16 after the surgery. Results. After the start of the dosed load on the injured limb, a fracture of the locking screw made of MC-10 alloy was radiographically recorded in all patients. The dynamic screw moves in the dynamic hole and the fracture is dynamized. The formation of callus in the fracture zone was unremarkable and took an average physiological time. The quality and structure of callus did not show any pathological features. Four months after the surgery, all patients were socially adapted and did not use additional support when moving. Conclusions. Based on the data obtained, it is possible to draw a conclusion about the possibility and advisability of using biodegradable implants made of magnesium alloy MS-10 in a dynamic BIOS of long bones of the human skeleton.


Author(s):  
Anda David ◽  
Mohamed Ali Marouani

This chapter focuses on the external effects of emigration on non-migrants, and particularly on the interactions with labor market outcomes in Tunisia before and after the revolution. Using the new Tunisia Labor Market Panel Survey (TLMPS), we conduct an in-depth analysis of the structure and dynamics of migration, including the profile of migrants and their origin households, mainly in terms of skills and spatial composition. We investigate transition matrices, employment status, income for current migrants and returnees, and the evolution of remittances. Our analysis confirms the role of emigration as a safety valve for the Tunisian labor market. Moreover, origin households of migrants have a significantly higher wealth index. Our analysis also tends to confirm the effects of remittances on labor supply of non-migrants, which can have a negative impact on Tunisia’s unemployment rate when a crisis in destination countries affects the remittance rate negatively.


Metals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1191
Author(s):  
Ryuichi Yamada ◽  
Shoichiro Yoshihara ◽  
Yasumi Ito

A stent is employed to expand a narrowed tubular organ, such as a blood vessel. However, the persistent presence of a stainless steel stent yields several problems of late thrombosis, restenosis and chronic inflammation reactions. Biodegradable magnesium stents have been introduced to solve these problems. However, magnesium-based alloys suffer from poor ductility and lower than desired fatigue performance. There is still a huge demand for further research on new alloys and stent designs. Then, as fundamental research for this, AZ31 B magnesium alloy has been investigated for the effect of equal-channel angular pressing on the fatigue properties. ECAP was conducted for one pass and eight passes at 300 °C using a die with a channel angle of 90°. An annealed sample and ECAP sample of AZ31 B magnesium alloy were subjected to tensile and fatigue tests. As a result of the tensile test, strength in the ECAP (one pass) sample was higher than in the annealed sample. As a result of the fatigue test, at stress amplitude σa = 100 MPa, the number of cycles to failure was largest in the annealed sample, medium in the ECAP (one pass) sample and lowest in the ECAP (eight passes) sample. It was suggested that the small low cycle fatigue life of the ECAP (eight passes) sample is attributable to severe plastic deformation.


2021 ◽  
Vol 122 ◽  
pp. 110443
Author(s):  
Rong Wang ◽  
Zhongbo Yuan ◽  
Qun Li ◽  
Bo Yang ◽  
Hong Zuo

2019 ◽  
Vol 20 (5) ◽  
pp. 1282-1291
Author(s):  
Sanjay Dhamija ◽  
Ravinder Kumar Arora

The article examines the impact of regulatory changes in the tax on dividends on the payout policy of Indian companies. The tax law was recently amended to levy tax on dividends received by large shareholders. As the promoters group is the largest shareholder, this is expected to have a negative impact on the payout policy of companies. Furthermore, companies with larger promoter holdings have a higher motivation to reduce their payout. The study covers 370 companies present in the BSE 500 Index and compares the dividend payout of the companies before and after the introduction of tax levy. The study finds that the newly introduced tax indeed caused a shift in the dividend policy of companies, particularly those companies which have high levels of inside ownership. The findings have significant implications for companies, investors and the government.


2002 ◽  
Vol 14 (1) ◽  
pp. 47-58 ◽  
Author(s):  
Ulla Eloniemi-Sulkava ◽  
Irma-Leena Notkola ◽  
Kaija Hämäläinen ◽  
Terhi Rahkonen ◽  
Petteri Viramo ◽  
...  

Objectives: To investigate what kind of changes spouse caregivers of demented patients experience after the onset of dementia (a) in the general atmosphere, happiness, and relations of marriage and (b) in the sexual side of marriage. Design: Semistructured telephone interviews of spouse caregivers of demented patients. Setting: Community-living demented patients and their spouse caregivers in eastern Finland. Participants: The spouse caregivers of 42 demented patients recruited from a previous intervention study. Measures: The questionnaire covered different areas of marriage from the time before and after the onset of dementia. Results: A statistically significant decline had occured in extent of happiness (p = .012), in equal relations (p = .001), and in patients' expressions of sexual needs (p < .001) when compared the time before and after dementia. Twenty-five (60%) of the caregivers reported that the demented patient had shown at least one negative sexual behavioral change during the course of dementia. Seven male patients (24%) had shown the behavioral symptom of constantly expressing need for making love. One in 10 caregivers had experienced positive sexual behavioral changes. In one third of the patients, the expressions of tenderness towards the caregiver had increased. Dementia did not affect significantly the general atmosphere of the marriage. Out of those still in home care, at 3 years from the onset of dementia, 19 couples (46%) continued to practice intercourse, at 5 years the number was 15 couples (41%), and at 7 years it had declined to 7 couples (28%). Conclusions: Dementing illness has a major negative impact on many dimensions of marriage. However, there are also positive changes and preserved aspects of marriage. Dementia seems to have a surprisingly little impact on whether the couple continues to have intercourse when compared with the general aging population.


2020 ◽  
pp. 105-111
Author(s):  
Giang Huynh Huong ◽  
Tan Nguyen Thi ◽  
Hung Nguyen Van

Background: Sciatica due to lumbar spondylosis is a common disease syndrome, include pathological signs from lumbar spine and sciatic nerve. It occurs for a long time and affects to working ability and daily life. Currently there are many methods of treatment with modern medicine and traditional medicine. Electroacupuncture combined with acupressure point, massage treatment and “Doc hoat tang ky sinh” remedy is a highly effective method on treating sciatica due to lumbar spondylosis. Objectives: To evaluate the effectives of electroacupuncture combined with acupressure point, massage treatment and “Doc hoat tang ky sinh” remedy on treating sciatica due to lumbar spondylosis. Materials and Method: A total of 43 patients was diagnosed sciatica caused by lumbar spondylosis who treated at Thua Thien Hue Traditional Medicine Hospital. The study was designed by method of prospective study, assessed the results before and after the treatment. Results: Very good: 34.9%; good: 34.9%; average 7%. There was not any unexpected effects observed in this trial. Conclusion: Electroacupuncture combined with acupressure point, massage treatment and “Doc hoat tang ky sinh” remedy is a effective method on treating sciatica caused by lumbar spondylosis. Key words: sciatica, lumbar spondylosis, acupuncture, electroacupuncture, acupressure point, massage treatment


2021 ◽  
Author(s):  
Daniel Osuna Gómez ◽  

This paper estimates the impact of the capture of leaders of criminal organizations on the labor market in municipalities where these organizations operated between 2004 and 2006. The difference-in-difference analysis compares different employment outcomes in cartel locations and the rest, before and after the capture of cartel leaders. The results show that captures caused a decrease in nominal wages and paid employment in cartel municipalities. Using Economic Census Data, I find that captures also caused a fall in the number of establishments and had a negative impact on other establishment outcomes. This document focuses exclusively on the impact of the capture of leaders of criminal organizations on the labor market until 2011 without studying other possible consequences, and thus does not make an integral assessment of this policy


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