The field experiments with barley of multiserial Vakula variety were conducted on gray forest soil of Kama region of theRepublic of Tatarstan. This experiment was carried out to identify the responsiveness of barley for fertilizers, methods of the basic soil cultivation and plant protection products. On average over three years of our research, the highest yield of barley (3.95 tons per hectare) was obtained in the flattered soil tillage and carrying out the calculated fertilizernorm in the way, when we used the seed protectant Stinger for pre- treatment of the soil. The yield was a little lower (3.88 tons per hectare), when we used Binoram for pre-sowing seed treatment, Albit was in the third place (3.80 tons per hectare), the fourth - Rizoagrin (3.65 tons per hectare), and the fifth - control (3.42 tons per hectare). The lowest barley yield (2.46 tons per hectare) were obtained on the background when not fertilized subsoiling tillage without the use of plant protection products. The use of seeds for incrustation, treated by Stinger chemical fungicide, increased the yield to 4.0 centner per hectare, compared with the control. When we used moldboard plowing, the yield declined in control to 4.7 centner per hectare and at fertilizered background to 4.9 centner per hectare, and at KSN soil treatment to3-5.3 centner per hectare. In arid 2010 the highest barley harvest was obtained at KSN-3 soil treating, on the second place is subsurface treatment and the third is plowing. Modern energy-saving methods of the basic soil cultivation, treating the calculated norms of fertilizers and use of plant protection products contribute to the production of planned productivity, saving fuel and lubricants, but they are unable to maintain phytosanitary conditions in barley fields within economic threshold. Taking inro account above-mentioned and the current state of agriculture in the steppe of the Volga region, it is necessary to alternate basic soil treatment methods, application of calculated norms of fertilizers and use protectants and biofungicides for pre-sowing treatment, considering fitoekzamination of seeds.