scholarly journals Open Access Serials: the High Dilution Research case.

2021 ◽  
Vol 7 (24) ◽  
pp. 159-162
Author(s):  
Carlos Renato Zacharias
Keyword(s):  
Open Access ◽  
Scientific Publication ◽  
High Dilution ◽  
New Paradigm ◽  
Community Needs ◽  
Theoretical Approaches ◽  
Acceso Abierto ◽  
High Dilutions ◽  
Experimental Trials ◽  
Electronic Support

Open Access Serial seems to be the new paradigm in scientific publication representing a growing tendency in all society segments. In particular, we are interested in the application of the Open Access serial model to High Dilution research. Such multidisciplinary area is opened to experts from all area of knowledge, requiring experimental trials and models as well theoretical approaches. However these researchers must be brought together around a thematic serial, peer-reviewed and easily accessed, able to reach a high impact parameter without lose its focus, where theoretical backgrounds and concepts could be presented and intensely discussed, ranging from experimental to theoretical approaches, basic to applied researches, also reporting clinical, historical and sociological papers. The features of the Open Access fit well with the High Dilution community needs for a scientific serial. Also, an electronic support makes possible divulgate larger texts, figures, movies, interviews, audio, and any other kind of multimedia. Thus, an Open Access scientific serial dedicated to High Dilutions would be very well accepted by the international community involved in high dilutions research. Keywords: Open access, high dilution, online serial.   Publicações de acesso aberto: o caso da pesquisa em altas diluições Resumo A publicação de acesso aberto parece ser o novo paradigma em publicação científica, representando uma tendéncia crescente em todos os segmentos da sociedade. Nos interessa, em particular, a aplicação desse modelo na pesquisa das altas diluições. Essa área multisciplinar está aberta a especialistas de todas as áreas do saber, precisando de testes e modelos experimentais, assim como de abordagens teóricas. No entanto, esses pesquisadores devem ser reunidos ao redor de um periódico temático, revisado por pares e de fácil acesso, capaz de alcançar parâmetros de alto impacto sem perder seu foco, onde os marcos de referéncia e conceitos teóricos possam ser apresentados e intensamente discutidos, abarcando do experimental ao teórico, pesquisa básica e aplicada, pesquisas clínicas, históricas e sociológicas. As características do sistema aberto se correspondem adequadamente com os requerimentos de um periódico para a comunidade ligada às altas diluições. Igualmente, o meio eletrônico permite divulgar textos e gráficos de maior tamanho, filmes, entrevistas, áudio e outros tipos de formatos multimedia. Por esse motivo, um periódico científico de acesso aberto dedicado às altas diluições seria muito bem recebido pela comunidade internacional. Palavras-chave: Acesso aberto, altas diluições, periódicos online.   Publicaciones de acceso abierto: el caso de la investigación en altas diluciones Resumen La publicación de acceso abierto parece ser el nuevo paradigma en publicación científica, representando una tendencia creciente en todos los segmentos de la sociedad. En particular, nos interesa la aplicación de este modelo en la investigación de altas diluciones. Tal área multidisciplinar está abierta a especialistas de todas las áreas del saber, necesitando aún ensayos y modelos experimentales, así como abordajes teóricos. Sin embargo, estos investigadores deben ser reunidos en torno de un periódico temático, revisado por pares y de fácil acceso, capaz de alcanzar parámetros de alto impacto sin perder su foco, adonde los marcos de referencia y conceptos teóricos puedan ser presentados e intensamente discutidos, abarcando desde lo experimental a lo teórico, investigación fundamental y aplicada, investigaciones clínicas, históricas y sociológicas. Las características del sistema abierto tienen buena correspondencia con los requerimientos de un periódico para la comunidad vinculada a las altas diluciones. Igualmente, el medio electrónico permite divulgar textos y gráficos de mayor tamanho, películos, entrevistas, y otros tipos de formatos multimedia. Por ese motivo, un periódico científico de acceso abierto dedicado a las altas diluciones sería muy bien recebido por la comunidad internacional. Palabras-clave: Acceso abierto, altas diluciones, revistas online.   Correspondence author: Carlos Renato Zacharias, [email protected] How to cite this article: Zacharias CR. Open Access Serials: the High Dilution Research case. Int J High Dilution Res [online]. 2008 [cited YYYY Mmm DD]; 7(24): 159-162. Available from: http://journal.giri-society.org/index.php/ijhdr/article/view/267/359.  

scholarly journals Incentives to Open Access: Perspectives of Health Science Researchers

Publications ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 29
Author(s):  
Carmen López-Vergara ◽  
Pilar Flores Asenjo ◽  
Alfonso Rosa-García
Keyword(s):  
Open Access ◽  
Technological Development ◽  
Scientific Publication ◽  
Economic Incentive ◽  
Health Sciences ◽  
Open Access Journal ◽  
Health Science ◽  
Open Access Publication ◽  
Open Access Journals ◽  
The Impact

Technological development has transformed academic publication over the past two decades and new publication models, especially Open Access, have captured an important part of the publishing market, traditionally dominated by the Subscription publication model. Although Health Sciences have been one of the leading fields promoting Open Access, the perspectives of Health Science researchers on the benefits and possibilities of Open Access remain an open question. The present study sought to unveil the perspective of researchers on scientific publication decisions, in terms of the Subscription and Open Access publication model, Gold Road. With this aim, we surveyed Spanish researchers in Health Sciences. Our findings show that the value of publishing in Open Access journals increases as the experience of the researcher increases and the less she/he values the impact factor. Moreover, visibility and dissemination of the results are the main determinants of publication when choosing an Open Access journal as the first option. According to the response of the researchers, the reduction of fees and the increase in financing are important economic incentive measures to promote the Open Access publication model. It is widely accepted that the volume of Open Access publications will increase in the future.

Therapeutic possibilities of Bothrops jararaca in high dilution

2021 ◽  
Vol 10 (36) ◽  
pp. 215-217
Author(s):  
Eduardo Costa Gaia Nazareth ◽  
Francisco José De Freitas
Keyword(s):  
Bacterial Infections ◽  
Complement C3 ◽  
Clinical Aspects ◽  
High Dilution ◽  
Complement Components ◽  
Physical Description ◽  
Bothrops Jararaca ◽  
High Dilutions ◽  
The Many ◽  
Therapeutic Possibilities

Introduction: The knowledge and use of the venom of Bothrops jararaca in high dilutions is still quite limited. One of the important properties is the use of one of its components, bradykinin, for the development of antihypertensive medication known as captopril. Other situations, such as clinical, local and systemic should receive more depth to the composition of Materia Medica related to various medical actions on the man and mammals in general. The systemic action of the bite of this snake, includes hemostasis disorders, culminating as bleeding gums, in addition to sweating, hypertension, and hypothermia. The action includes local pain and swelling with bruising, bleeding and often blistering and tissue necrosis. The action on the immune system, through action on the complement C3 and other complement components may show its possible use in cases of bacterial infections, including mycobacteria, as presented in the study of 1970 Vanessa Birdsey, "Interactions of poisons toxic with the addition, "the journal of Immunology 1971. Today, this poison has a toxicology published by Anibal Melgarejo, "Venomous Animals of Brazil", 2003, which subsidizes the development of study for its use in high dilutions, and a comprehensive study of the biology of the animal itself. Published studies on biomolecular analysis add more details about the relations of the poison and mammals. All these characteristics suggest the use of poison as a homeopathic remedy. Objective: To investigate the therapeutic possibilities in high dilutions of the venom of the snake Bothrops jararaca, expanding its clinical use. Methodology: Methodological description of this poison in contemporary bases including: Origin, physical description chemistry, toxicology, pharmacology and medicine in preparation of high dilution, general action, specific actions on systems or organs, sensations, modalities, concomitants, etiological indications relations main clinics. Results: Defining the therapeutic indications such as modulation of the complement system, action on the cardiovascular system, among other uses, by Bothrops jararaca in high dilution. Conclusion: This evaluation can be used for different sources of products and allows the rational use of Bothrops jararaca in high dilution. The results can and should be complemented by clinical studies and pathogenetic. Bacterial infectious diseases such as tuberculosis and leprosy, and autoimmune disease LES and may receive treatment studies with the drug based on Bothrops jararaca snake venom because they are indirectly associated with them via similarity of the failure of complement, an important marker for bacterial the defense of mammals. Action on clinical aspects like hypertension, sweating, hypothermia and necrosis shall be seen. Perhaps the search for the stimulation of complement show a new pathway for the harmonization, long-predicted by Hahnemann, Hering and searched for among the many that followed the creator of this therapy.

scholarly journals Open Access in UCL: A New Paradigm for London's Global University in Research Support

2014 ◽  
Vol 45 (4) ◽  
pp. 282-295 ◽  
Author(s):  
Paul Ayris ◽  
Erica McLaren ◽  
Martin Moyle ◽  
Catherine Sharp ◽  
Lara Speicher
Keyword(s):  
Open Access ◽  
New Paradigm ◽  
Research Support ◽  
Global University

scholarly journals Analisis Keamanan Website Open Journal System Menggunakan Metode Vulnerability Assessment

2020 ◽  
Vol 7 (4) ◽  
pp. 853
Author(s):  
Imam Riadi ◽  
Anton Yudhana ◽  
Yunanri W
Keyword(s):  
Open Access ◽  
Vulnerability Assessment ◽  
Web Application ◽  
Scientific Publication ◽  
Information Gathering ◽  
Public Knowledge ◽  
Audit Process ◽  
Sql Injection ◽  
Web Application Security ◽  
Access Port

<p class="Body"><em>Open Journal System</em> (OJS) merupakan perangkat lunak yang berfungsi sebagai sarana publikasi ilmiah dan digunakan diseluruh dunia. OJS yang tidak dipantau beresiko diserang oleh <em>hacker</em>.  Kerentanan yang di timbulkan oleh <em>hacker</em> akan berakibat buruk terhadap performa dari sebuah OJS.  Permasalahan yang dihadapi pada sistem OJS meliputi <em>network</em>, <em>port discover</em>, proses audit <em>exploit</em> sistem OJS. Proses audit sistem pada OJS mencakup <em>SQL Injection</em>, melewati <em>firewall </em>pembobolan <em>password</em>. Parameter input yang digunakan adalah IP<em> </em><em>address</em> dan <em>p</em><em>ort open access</em>. Metode yang digunakan adalah <em>vulnerability assessment</em>. Yang terdiri dari beberapa tahapan seperti <em>information gathering</em> atau <em>footprinting</em>, <em>scanning vulnerability</em>, <em>reporting</em>. Kegiatan ini bertujuan untuk mengidentifikasi celah keamanan pada <em>website o</em><em>pen j</em><em>ournal s</em><em>ystem</em> (OJS). Penelitian ini menggunakan <em>o</em><em>pen w</em><em>eb a</em><em>pplication s</em><em>ecurity p</em><em>roject</em> (OWASP). Pengujian yang telah dilakukan berhasil mengidentifikasi 70 kerentanan<em> high</em>, 1929 <em>medium</em>,<em> </em>4050 <em>low</em> pada OJS, Total nilai <em>vulnerabilit</em>y pada OJS yang di uji coba sebesar 6049. Hasil pengujian yang dilakukan menunjukkan bahwa pada OJS versi 2.4.7 memiliki banyak celah kerentanan atau <em>vulnerability</em>, tidak di rekomendasi untuk digunakan. Gunakanlah versi terbaru yang dikeluarkan oleh pihak OJS <em>Public knowledge  project</em> (PKP).</p><p class="Body"> </p><p class="Body"><em><strong>Abstract</strong></em></p><p class="Judul21"><em>The Open Journal System (OJS) is </em><em>A </em><em>software that functions as a means of scientific publication and is used throughout the world. OJS that is not monitored is at risk of being attacked by hackers. Vulnerabilities caused by hackers will adversely affect the performance of an OJS. The problems faced by the OJS system include the network, port discover, OJS system audit exploit process. The system audit process on the OJS includes SQL Injection, bypassing the firewall breaking passwords. The input parameters used are the IP address and open access port. The method used is a vulnerability assessment. Which consists of several stages such as information gathering or footprinting, scanning vulnerability, reporting. This activity aims to identify security holes on the open journal system (OJS) website. This study uses an open web application security project (OWASP). Tests that have been carried out successfully identified 70 vulnerabilities high, 1929 medium, 4050 low in OJS, the total value of vulnerability in OJS which was tested was 6049. The results of tests conducted showed that in OJS version 2.4.7 had many vulnerabilities or vulnerabilities, not on recommendations for use. Use the latest version issued by the OJS Public Knowledge Project (PKP).</em></p><p class="Body"><em><strong><br /></strong></em></p>

scholarly journals Bias in Homeopathy: Technical Note

2017 ◽  
Vol 4 (1) ◽  
pp. 25-28
Author(s):  
Salvatore Chirumbolo
Keyword(s):  
Biological Activity ◽  
Chemical Species ◽  
Zero Point ◽  
Technical Note ◽  
Chemical System ◽  
High Dilution ◽  
The Real ◽  
Real Nature ◽  
High Dilutions ◽  
Species Being

Homeopathy is fundamentally based on the assumption that a biological activity is borne by a chemical system made by a molecular solute within a solvent that is diluted and mechanically stressed an undefined number of times and then reaches a zero point where molecules disappear and the solvent is the only chemical species being left. With the exception of an author who recently stated “We have been working in this field for over 20 years [35], and are thus perfectly aware of the issues related to the “plausibility” of high-dilution pharmacology, particularly when using dilutions beyond Avogadro’s constant”, yet no evidence was reported to date about the real nature of homeopathic high dilutions.

scholarly journals LA INVESTIGACIÓN CIENTÍFICA EN TIEMPOS DEL COVID 19: OBJETOS NUEVOS Y DESAFÍOS

2020 ◽  
Vol 7 (2) ◽  
pp. 57
Author(s):  
Iván Montes Iturrizaga
Keyword(s):  
Open Access ◽  
Acceso Abierto

ÁGORA es la Revista de Investigación Científica de la Universidad María Auxiliadora que, a lo largo de sus siete primeros años de vida, ha venido divulgando en formato acceso abierto (open access) contribuciones originales de estudiosos nacionales y extranjeros. Tal es así que, en su identidad como medio arbitrado – preferentemente- orientado a los ámbitos de las ciencias de la salud, llega a su segundo número del año a retratar en casi todos sus artículos objetos de estudio asociados con el COVID 19.

scholarly journals ¿Pero de verdad saben qué es el acceso abierto?

revista PH ◽  
2020 ◽  
pp. 140
Author(s):  
Ángel M. Delgado-Vázquez
Keyword(s):  
Open Access ◽  
Redes Sociales ◽  
Acceso Abierto

El desconocimiento del acceso abierto por parte de los investigadores en formación incide negativamente en su uso como alternativa al uso masivo de las herramientas que dan soporte al conocido como black open access a la hora de acceder a las publicaciones científicas. De igual modo, esto unido a la dificultad de uso de los repositorios en comparación con las redes sociales científicas, incide significativamente a la hora de comprometerse con el depósito de sus propias investigaciones.

Diluted versus potentitized probes of silver nitrate (10e-2 to 10e-10) and wheat germination

2021 ◽  
Vol 15 (4) ◽  
pp. 22-23
Author(s):  
Corinne Kraus
Keyword(s):  
Silver Nitrate ◽  
Triticum Aestivum L ◽  
Distilled Water ◽  
Special Issue ◽  
High Dilution ◽  
Wheat Seedlings ◽  
Significant Difference ◽  
High Dilutions ◽  
Group A ◽  
Wheat Germination

Corinne Kraus, Ute Knobloch, Scherer Waltraud, Peter Christian Endler Interuniversity College for Health and Development Graz / Castle of Seggau, Austria Background In 1926, an influence of a homeopathically prepared high dilution of silver nitrate on the growth of coleoptiles of wheat seedlings was described (Kolisko 1926). Later, in an extensive series of experiments, wheat was observed under the influence of extremely diluted agitated silver nitrate (10e-23, “24x”). Stalk lengths clearly indicate that development is enhanced by the probe silver nitrate 24x as compared to control (Scherer et al. 2015). A preliminary experiment was performed in early autumn 2015 on stalk growth of wheat seedlings treated with (not potentized) dilutions of silver nitrate 10e-6 to 10e-10 (“6e to 10e”), compared to potentized silver nitrate 6x to 10x (N = 100 per group). A clear, albeit not statistically significant trend was observed of 6x-stalks being longer (23.4 + 16.2 mm) than 6e-stalks (13.0 + 10.9 mm). Objective The aim of this study was to investigate the influence of diluted versus potentized low dilutions of silver nitrate (10e-2 to 10e-10) on wheat germination. Method The experiments were performed in late autumn 2015 on wheat grain (Triticum aestivum L., Capo variety). The grains were observed under the influence of aqueous solutions 10-2 to 10-10 part per weight of silver nitrate, either diluted in steps of 1 : 10 in distilled water by mere pipetting (probes “2e – 10e”), or diluted and agitated in steps of 1:10 (to create potentized probes “2x – 10x”). Untreated distilled water (“w”) served as an additional control. All probes were applied blindly. 100 grains were observed per treatment group in each of the groups resulting a total of 2,000 grains. Grains were placed in glass dishes, probes were added and dishes were covered with lids and placed in drawers . The following endpoint criteria were defined: K1 = visible emergence of sprout material, K2 = lifting of the operculum and emergence of the sprout and W1 = development of three roots.   Result Germination rates K1 of seedlings treated with “w”-probes (blue), with “e”-probes ranging from 2e to 10e (black) and with “x”-probes ranging from 2x to 10x (red) at the measuring points 20h, 24h and 28h (from left to right for each of the probes). In K1, K2 and W, there is an obvious increase of germination rates from the high to the lower concentrations of silver nitrate, both in the “e” and in the “x”-groups and observable at 20h, 24h and 28h (p < 0.01). In contrast, germination rates of the two „w“-probes are practically alike (p > 0,05) When “e” and “x”-data are compared, germination rates are higher under the influence of “x” than under the influence of “e” (p < 0.01 for the pooled “x”-values compared to the pooled “e”-values with regard to K1 as well as K2 as well as W). Conclusion: A significant difference was found between wheat grains treated with mere dilutions compared to grains treated with potentised dilutions. References 1. Endler PC, Belavite P, Bonamin L,Jäger T, Mazon S. Replication of fundamental research models in ultra high dilutions 1994 and 2015 – update on a bibliometric study. Special issue Homeopathy London. 2015 a Oktober;104(4):234-45. 2. Endler PC, Schulte J, Stock-Schroeer B, Stephen S. Ultra high Dilution 1994 revisited 2015 – the state of follow-up research. Special issue Homeopathy London. 2015 b Oktober;104(4):223-6. 3. Kolisko L. Physiologischer Nachweis der Wirksamkeit kleinster Entitäten bei 7 Metallen – Wirkung von Licht und Pflanzen auf das Pflanzenwachstum. Dornach Schweiz: Philosophisch-Anthroposophischer Verlag am Goetheanum; 1926. 4. Kraus C, Knobloch U. Diluted versus diluted and agitated probes of silver nitrate (10-2 to 10-10) and wheat germination, Thesis (MSc); branch campus UCN at Interuniversity College Graz / Schloss Seggau; 2016. 5. Scherer-Pongratz W., Endler P.C., Lothaller H., Stephen S. Wheat and ultra high diluted silver nitrate – further experiments and re-analysis of data. Special issue Homeopathy London. 2015;104(4):246-9.

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