Large-scale flume modelling of segregation processes in debris flows

2020 ◽  
Author(s):  
Julia Kimball ◽  
W Andrew Take
Keyword(s):  
Debris Flows ◽  
Large Scale ◽  
Multicomponent Mixture ◽  
Granular Flows ◽  
Particle Sizes ◽  
Deposit Morphology ◽  
Multicomponent Mixtures ◽  
Particle Segregation ◽  
Experimental Strategies ◽  
Landslide Deposit

<p>Debris flows are powerful natural hazards posing risk to life, infrastructure, and property.  Understanding the particle scale interactions in these flows is a key component in the development of models to predict the mobility, distal reach, and hazard posed by a given event. In this study we focus on the process of segregation in debris flows, using a large-scale landslide flume to explore segregation in mixtures of 25 mm, 12 mm, 6 mm, and 3 mm diameter particle sizes. Sample volumes, consisting of a multicomponent mixture of materials, up to 1 m<sup>3</sup> in size are released at the top of a 6.8 m long, 2.1 m wide slope, inclined at 30 degrees to the horizontal to initiate flow. Subsequent analysis is completed to determine the extent of vertical and longitudinal segregation of the post-landslide deposit morphology. A range of experimental strategies are explored to provide quantitative measures of particle segregation. Particle size is identified via image analysis and various techniques are applied for the longitudinal sectioning of the deposit, using measurements of segregation at the sidewall of the transparent flume, contrasted with planes measured from within the centre of the deposit. Further, replicate experiments are shown to quantify the probabilistic variation in segregation for multicomponent mixtures of dry granular flows, as well as initially saturated granular flows, to explore the effect of pore fluid on segregation processes.</p>

scholarly journals Large Scale Physical Modelling Study of a Flexible Barrier under the Impact of Granular Flows

2018 ◽  
Author(s):  
Dao-Yuan Tan ◽  
Jian-Hua Yin ◽  
Wei-Qiang Feng ◽  
Jie-Qiong Qin ◽  
Zhuo-Hui Zhu
Keyword(s):  
Debris Flows ◽  
Large Scale ◽  
Impact Force ◽  
Granular Flows ◽  
Physical Modelling ◽  
Flexible Barrier ◽  
Impact Forces ◽  
Flexible Barriers ◽  
Open Question ◽  
The Impact

Abstract. Flexible barriers are being increasingly applied to mitigate the danger of debris flows. However, how barriers can be better designed to withstand the impact loads of debris flows is still an open question in natural hazard engineering. Here we report an improved large-scale physical modelling device and the results of two consecutive large-scale granular flow tests using this device to study how flexible barriers react under impact from granular flows. In the study, the impact force directly on the flexible barrier and the impact force transferred to the supporting structures are measured, calculated and compared. Based on the comparison, the impact loading attenuated by the flexible barrier is quantified. The hydro-dynamic and hydro-static approaches are also validated using the calculated impact forces.

scholarly journals Large-scale physical modelling study of a flexible barrier under the impact of granular flows

2018 ◽  
Vol 18 (10) ◽  
pp. 2625-2640 ◽  
Author(s):  
Dao-Yuan Tan ◽  
Jian-Hua Yin ◽  
Wei-Qiang Feng ◽  
Jie-Qiong Qin ◽  
Zhuo-Hui Zhu
Keyword(s):  
Debris Flows ◽  
Large Scale ◽  
Impact Force ◽  
Granular Flows ◽  
Physical Modelling ◽  
Flexible Barrier ◽  
Static Approach ◽  
Flexible Barriers ◽  
Open Question ◽  
The Impact

Abstract. Flexible barriers are being increasingly applied to mitigate the danger of debris flows. However, how barriers can be better designed to withstand the impact loads of debris flows is still an open question in natural hazard engineering. Here we report an improved large-scale physical modelling device and the results of two consecutive large-scale granular flow tests using this device to study how flexible barriers react under the impact of granular flows. In the study, the impact force directly on the flexible barrier and the impact force transferred to the supporting structures are measured, calculated, and compared. Based on the comparison, the impact loading attenuated by the flexible barrier is quantified. The hydro-dynamic approaches with different dynamic coefficients and the hydro-static approach are validated using the measured impact forces.

WHAT CAN WE LEARN FROM SEISMIC RECORDINGS OF DEBRIS FLOWS? PRELIMINARY FINDINGS FROM LARGE SCALE SEISMIC EXPERIMENTS AT THE USGS DEBRIS-FLOW FLUME

2016 ◽  
Author(s):  
Kate E. Allstadt ◽  
◽  
Maxime Farin ◽  
Jason W. Kean ◽  
Richard M. Iverson ◽  
...  
Keyword(s):  
Debris Flow ◽  
Debris Flows ◽  
Large Scale

scholarly journals Why does the spread of COVID-19 vary greatly in different countries? Revealing the efficacy of face masks in epidemic prevention

2021 ◽  
Vol 149 ◽  
Author(s):  
Jincheng Wei ◽  
Shurui Guo ◽  
Enshen Long ◽  
Li Zhang ◽  
Bizhen Shu ◽  
...  
Keyword(s):  
Social Isolation ◽  
Large Scale ◽  
Experimental Studies ◽  
Weighted Average ◽  
Filtration Efficiency ◽  
Volume Distribution ◽  
Particle Sizes ◽  
Economic Activities ◽  
Protection Measure ◽  
Source Of Infection

Abstract The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is highly contagious, and the coronavirus disease 2019 (COVID-19) pandemic caused by it has forced many countries to adopt ‘lockdown’ measures to prevent the spread of the epidemic through social isolation of citizens. Some countries proposed universal mask wearing as a protection measure of public health to strengthen national prevention efforts and to limit the wider spread of the epidemic. In order to reveal the epidemic prevention efficacy of masks, this paper systematically evaluates the experimental studies of various masks and filter materials, summarises the general characteristics of the filtration efficiency of isolation masks with particle size, and reveals the actual efficacy of masks by combining the volume distribution characteristics of human exhaled droplets with different particle sizes and the SARS-CoV-2 virus load of nasopharynx and throat swabs from patients. The existing measured data show that the filtration efficiency of all kinds of masks for large particles and extra-large droplets is close to 100%. From the perspective of filtering the total number of pathogens discharged in the environment and protecting vulnerable individuals from breathing live viruses, the mask has a higher protective effect. If considering the weighted average filtration efficiency with different particle sizes, the filtration efficiencies of the N95 mask and the ordinary mask are 99.4% and 98.5%, respectively. The mask can avoid releasing active viruses to the environment from the source of infection, thus maximising the protection of vulnerable individuals by reducing the probability of inhaling a virus. Therefore, if the whole society strictly implements the policy of publicly wearing masks, the risk of large-scale spread of the epidemic can be greatly reduced. Compared with the overall cost of social isolation, limited personal freedoms and forced suspension of economic activities, the inconvenience for citizens caused by wearing masks is perfectly acceptable.

Reanalysis of Flash Floods and Debris Flows on two continents and their management strategies

2021 ◽  
Author(s):  
Juan Daniel Rios-Arboleda
Keyword(s):  
Risk Management ◽  
Developing Countries ◽  
South America ◽  
Debris Flow ◽  
Debris Flows ◽  
Large Scale ◽  
Management Strategies ◽  
Original Analysis ◽  
Risk Management Strategies ◽  
Latitudinal Patterns

<p>This research expands the original analysis of Baker and Costa (1987) including data from Europe and South America with the objective to understand if there are emerging latitudinal patterns. In addition, the threshold proposed by Zimmermann et al. (1997) it is evaluated with the data from tropical zones finding that this is a good predictor.</p><p>Mainly, recent Debris Flow occurred in South America are analyzed with the aim of identifying the best risk management strategies and their replicability for developing countries, particularly, the cases that have occurred in Colombia and Venezuela in the last 30 years are analyzed in order to compare management strategies and understand which are the most vulnerable areas to this phenomenon.</p><p>It is concluded that large-scale and multinational projects such as SED ALP are required in South America to better characterize events that have left multiple fatalities (sometimes hundreds of people) and better understand how to manage the risk on densely populated areas.</p><p>Finally, the use of amateur videos is proposed to characterize these events in nations with limited budgets for projects such as SED ALP, methodology that will be described extensively in later works.</p>

Characteristics, Causes and Hazards of Large-Scale Debris Flows on June 23 at Haitong Watershed, Tibet, China

2017 ◽  
pp. 581-592
Author(s):  
Ge Yonggang ◽  
Zou Qiang ◽  
Zhang Jianqiang ◽  
Guo Xiaojun
Keyword(s):  
Debris Flows ◽  
Large Scale

Research on Motion Characteristics and Formation Mechanism of Debris Flow

2014 ◽  
Vol 711 ◽  
pp. 388-391
Author(s):  
Ji Wei Xu ◽  
Ming Dong Zhang ◽  
Mao Sheng Zhang
Keyword(s):  
Debris Flow ◽  
Formation Mechanism ◽  
Debris Flows ◽  
Catchment Area ◽  
Large Scale ◽  
Large Range ◽  
Extreme Rainfall ◽  
Small Catchment ◽  
Rainfall Characteristics ◽  
Motion Characteristics

On July 9 2013, debris flows occurred around Longchi town with large scale and wide harm, which was a great threat to people's life and property as well as reconstruction work. Debris flow ditch in the surrounding town was studied. This paper focused on loose materials, topography and rainfall characteristics, and explored the formation mechanism of debris flow in Longchi town. The result shows that: a small catchment area in valleys also have the risk of large range of accumulation of debris flow, the debris flow is caused by a lot of loose materials in mountains after earthquake and extreme rainfall. Research results contribute to a better understanding of trigger condition of debris flow after earthquake.

The Scalability of Wet Ball Milling for The Production of Nanosuspensions

2019 ◽  
Vol 7 (2) ◽  
pp. 147-161 ◽  
Author(s):  
Maria L.A.D. Lestari ◽  
Rainer H. Müller ◽  
Jan P. Möschwitzer
Keyword(s):  
Ball Milling ◽  
Large Scale ◽  
Milling Time ◽  
High Energy ◽  
Small Scale ◽  
Particle Sizes ◽  
Scale Production ◽  
Batch Mode ◽  
Pharmaceutical Ingredients ◽  
Large Scale Production

Background: Miniaturization of nanosuspensions preparation is a necessity in order to enable proper formulation screening before nanosizing can be performed on a large scale. Ideally, the information generated at small scale is predictive for large scale production. Objective: This study was aimed to investigate the scalability when producing nanosuspensions starting from a 10 g scale of nanosuspension using low energy wet ball milling up to production scales of 120 g nanosuspension and 2 kg nanosuspension by using a standard high energy wet ball milling operated in batch mode or recirculation mode, respectively. Methods: Two different active pharmaceutical ingredients, i.e. curcumin and hesperetin, have been used in this study. The investigated factors include the milling time, milling speed, and the type of mill. Results: Comparable particle sizes of about 151 nm to 190 nm were obtained for both active pharmaceutical ingredients at the same milling time and milling speed when the drugs were processed at 10 g using low energy wet ball milling or 120 g using high energy wet ball milling in batch mode, respectively. However, an adjustment of the milling speed was needed for the 2 kg scale produced using high energy wet ball milling in recirculation mode to obtain particle sizes comparable to the small scale process. Conclusion: These results confirm in general, the scalability of wet ball milling as well as the suitability of small scale processing in order to correctly identify the most suitable formulations for large scale production using high energy milling.

scholarly journals Applying Microfluidics for the Production of the Cationic Liposome-Based Vaccine Adjuvant CAF09b

Pharmaceutics ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 1237
Author(s):  
Signe Tandrup Schmidt ◽  
Dennis Christensen ◽  
Yvonne Perrie
Keyword(s):  
Large Scale ◽  
Colloidal Stability ◽  
Scale Up ◽  
Cationic Liposome ◽  
Poly I:C ◽  
Particle Sizes ◽  
Adjuvant Activity ◽  
Lipid Film ◽  
Gmp Production

Subunit vaccines require particulate adjuvants to induce the desired immune responses. Pre-clinical manufacturing methods of adjuvants are often batch dependent, which complicates scale-up for large-scale good manufacturing practice (GMP) production. The cationic liposomal adjuvant CAF09b, composed of dioctadecyldimethylammonium bromide (DDA), monomycoloyl glycerol analogue 1 (MMG) and polyinosinic:polycytidylic acid [poly(I:C)], is currently being clinically evaluated in therapeutic cancer vaccines. Microfluidics is a promising new method for large-scale manufacturing of particle-based medicals, which is scalable from laboratory to GMP production, and a protocol for production of CAF09b by this method was therefore validated. The influence of the manufacture parameters [Ethanol] (20–40% v/v), [Lipid] (DDA and MMG, 6–12 mg/mL) and dimethyl sulfoxide [DMSO] (0–10% v/v) on the resulting particle size, colloidal stability and adsorption of poly(I:C) was evaluated in a design-of-experiments study. [Ethanol] and [DMSO] affected the resulting particle sizes, while [Lipid] and [DMSO] affected the colloidal stability. In all samples, poly(I:C) was encapsulated within the liposomes. At [Ethanol] 30% v/v, most formulations were stable at 21 days of manufacture with particle sizes <100 nm. An in vivo comparison in mice of the immunogenicity to the cervical cancer peptide antigen HPV-16 E7 adjuvanted with CAF09b prepared by lipid film rehydration or microfluidics showed no difference between the formulations, indicating adjuvant activity is intact. Thus, it is possible to prepare suitable formulations of CAF09b by microfluidics.

scholarly journals Risk assessment of debris flow based on group decision making – A case study of Luanchuan County, Henan Province, China

2018 ◽  
Vol 175 ◽  
pp. 04025
Author(s):  
Pengyu Chen ◽  
Ying Kong
Keyword(s):  
Risk Assessment ◽  
Decision Making ◽  
Debris Flow ◽  
Group Decision Making ◽  
Debris Flows ◽  
Large Scale ◽  
Group Decision ◽  
Henan Province ◽  
Comprehensive Assessment ◽  
Material Sources

Luanchuan County, located in the mountains of Western Henan Province, is characterized by poor geological environment and abundant material sources and rainfalls. Debris flows have occurred many times in this county, and in some gully debris flows exhibit a large scale, requiring risk assessment. In the multi-factor comprehensive assessment methods for debris flow risk, it is really important to determine the weight of each factor since this affects the reliability of the assessment results. Given that the subjective weighting method can accurately reflect the importance of each factor, in order to improve the reliability of subjective weighting, the group decision making method is used to determine the weight of each factor. Group decision making is realized using the analytic hierarchy process and the data fusion algorithm. In this method, the expert combination weight is determined; on this basis, a model for comprehensive assessment of debris flow risk is established by the linear weighted sum method, and risk assessment is performed for gullies with medium to large-scale debris flows in the study area. The assessment results show that all debris flow gullies face minor to moderate risks. For gullies with high risk degree, it is suggested to timely clear material sources in channels and construct or reinforce retaining dams in order to prevent re-occurrence of debris flows.

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