scholarly journals COVID 19; A SURGICAL PERSPECTIVE

2020 ◽  
Vol 10 (2) ◽  
Author(s):  
Anwar Ul Haque
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Virus Disease ◽  
Unknown Origin ◽  
Healthcare Systems ◽  
Hubei Province ◽  
Causative Organism ◽  
The Novel ◽  
Contagious Disease ◽  
The World

The novel corona virus disease started  at Wuhan  in Hubei province of China as pneumonia of unknown origin  and it was found that  the causative organism of Coronavirus Disease 2019(COVID-19) was Severe Acute Respiratory Syndrome Coronavirus –type 2 (SARS-CoV-2).  Healthcare systems all over the world nearly collapsed due to unprecedented spread of the virus and the disease, COVID-19 was notified as a pandemic by WHO on March 11,2020.1,2  Until October 2020 more than 37 million cases and more than one million deaths have been reported worldwide from this highly contagious disease.

scholarly journals Exploring Dependence of COVID-19 on Environmental Factors and Spread Prediction in India

2020 ◽  
Author(s):  
Hemant Bherwani ◽  
Ankit Gupta ◽  
Saima Anjum ◽  
Avneesh Anshul ◽  
Rakesh Kumar
Keyword(s):  
Response Surface Methodology ◽  
Relative Humidity ◽  
Environmental Factors ◽  
Severe Acute Respiratory Syndrome ◽  
Virus Disease ◽  
Action Plan ◽  
The Novel ◽  
The World ◽  
Novel Coronavirus ◽  
The Impact

Abstract The pandemic of “Corona Virus Disease 2019” or COVID-19 has taken the world by storm. Majority of nations of the world have been challenged by the novel coronavirus, which is supposedly of zoonotic origin and is known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The present work attempts to evaluate the spread of COVID-19 in India. The methodology of assessment uses SEIR (Susceptible-Exposed-Infectious-Removed) model to establish the impact of socio-behavioural aspect, especially social distancing, affecting the numbers of COVID-19 cases per day. The lockdown initiated by Government of India (GoI) scenario is weighed against a scenario with a possible initiation of community spread due to crowded gatherings in India. The resultant changes, as against the lockdown scenario, has been reported in terms of the increase in the number of cases and stretch of the timeline to mitigate the COVID-19 spread. Impact of environmental factors like temperature and relative humidity have also been analyzed using statistical methods, including Response Surface Methodology (RSM) and Correlation. It has been found that the spread of cases is dependent on environmental conditions, i.e. temperature and relative humidity. This study is expected to help the policymakers and stakeholders to device an improved action plan to alleviate the COVID-19 spread, especially in India.

Covid-19, SARS -CoV-2, Origin, transmission and treatment aspects, a brief review

2020 ◽  
Vol 20 ◽  
Author(s):  
Shahid Nawaz
Keyword(s):  
Mortality Rate ◽  
Severe Acute Respiratory Syndrome ◽  
Clinical Manifestation ◽  
Virus Disease ◽  
The Novel ◽  
Research Activities ◽  
Corona Virus ◽  
Global Pandemic ◽  
The World

: The emergence of severe acute respiratory syndrome (SARS) in Wuhan (china) named as corona virus disease 19(covid-19) caused by the novel corona virus SARS-CoV-2 has caused hundreds of thousands of mortalities across the world ,while the mortality rate is in millions, leading it to be declared as a global pandemic. Numerous research activities are undergoing to reveal the disease and etiological features of covid-19. In this review, some of the interesting aspects of covid-19 are discussed, that includes, the origin of the SARS-CoV-2, clinical manifestation, treatment and future aspects of the disease.

scholarly journals Coronaviruses – a new old menace

2021 ◽  
Author(s):  
Anna Golke ◽  
Karolina Piekarska ◽  
Tomasz Dzieciątkowski
Keyword(s):  
Middle East ◽  
Severe Acute Respiratory Syndrome ◽  
Healthcare Systems ◽  
Middle East Respiratory Syndrome ◽  
Control Measures ◽  
The Novel ◽  
Global Impact ◽  
Infection Control Measures ◽  
The World ◽  
Novel Coronavirus

current pandemic caused by novel coronavirus SARS-CoV-2 pandemic has been described as a global health emergency. The outbreak of this virus has raised a number of questions: what exactly is SARS-CoV-2? How transmissible the novel coronavirus is? How severely affected are patients infected with SARS-CoV-2? What are the risk factors for COVID-19? What are the differences between this novel coronavirus and other coronaviruses? To answer these questions, a comparative study of three pathogenic coronaviruses that primarily invade the human respiratory system and may cause death, namely, severe acute respiratory syndrome (SARS-CoV-1), Middle East respiratory syndrome (MERS-CoV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Middle East respiratory syndrome coronavirus (MERS-CoV). This review describes the source of origin, transmission, and pathogenicity of these viruses. Prevention of SARS-CoV-2 spreading entails home isolation of suspected cases and those with mild illnesses and strict infection control measures at hospitals that include contact and droplet precautions. The novel coronavirus spreads faster than its two predecessors – the SARS-CoV-1 and MERS-CoV – but has lower fatality rate. The global impact of this new pandemic is still uncertain, but it is a challenge to healthcare systems around the world.

scholarly journals Emerging pandemic COVID-19: myths and facts

2020 ◽  
Vol 6 (7) ◽  
pp. 283
Author(s):  
Rohit Vadala ◽  
Isabella Princess
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Clinical Presentation ◽  
Surface Protein ◽  
Respiratory Viruses ◽  
The Novel ◽  
Nucleocapsid Proteins ◽  
The World ◽  
The Common ◽  
Human Infections ◽  
Relationship Of

<p>The first theory which has established itself across the world is that COVID-19 is a “new virus”. It is rather wise to call it a “new strain” of a pre-existing coronavirus since history clearly denotes cases of coronavirus surfacing the world in past years beginning as early as mid-1960s.Including this novel strain of the virus, seven strains of coronaviruses have been commonly associated with human infections. Coronaviruses are primarily respiratory viruses causing infections ranging from mild to severe involvement of the respiratory tract. The common cold strains of coronavirus are 229E alpha coronavirus, NL63 alpha coronavirus, OC43 beta coronavirus and HKU1 beta coronavirus.The acute respiratory distress causing strains are severe acute respiratory syndrome (SARS) beta CoV causing SARS, MERS beta CoV causing Middle East respiratory syndrome (MERS) and the very novel COVID-19. Researchers and molecular biologists have confirmed phylogenetic relationship of COVID-19 with a 2015 Chinese bat strain of SARS CoV.<sup> </sup>Mutations to the surface protein as well as nucleocapsid proteins were demonstrated. These two mutations predicts the characteristics such as higher ability to infect as well as enhanced pathogenicity of COVID-19 as compared to older SARS strain. For this reason and with similarities in clinical presentation the novel strain has been named as SARS-CoV-2.</p>

scholarly journals Does the novel coronavirus 2019 like heart more than the other family members of coronaviruses?

2020 ◽  
Vol 12 (2) ◽  
pp. 156-157
Author(s):  
Mohammad Mostafa Ansari Ramandi ◽  
Mohammadreza Baay ◽  
Nasim Naderi
Keyword(s):  
Middle East ◽  
Severe Acute Respiratory Syndrome ◽  
Family Members ◽  
Middle East Respiratory Syndrome ◽  
The Other ◽  
The Novel ◽  
The World ◽  
Future Challenges ◽  
Novel Coronavirus ◽  
Coronavirus Infections

The disaster due to the novel coronavirus disease 2019 (COVID-19) around the world has made investigators enthusiastic about working on different aspects of COVID-19. However, although the pandemic of COVID-19 has not yet ended, it seems that COVID-19 compared to the other coronavirus infections (the Middle East Respiratory Syndrome [MERS] and Severe Acute Respiratory Syndrome [SARS]) is more likely to target the heart. Comparing the previous presentations of the coronavirus family and the recent cardiovascular manifestations of COVID-19 can also help in predicting possible future challenges and taking measures to tackle these issues.

Coronavirus and Fingerprint Technology

2021 ◽  
Vol 13 (4) ◽  
pp. 1-16
Author(s):  
Gabriel B. Iwasokun
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Viral Infection ◽  
Virus Disease ◽  
High Rate ◽  
Corona Virus ◽  
The World ◽  
Almost All

The corona virus disease, otherwise known as COVID-19, is an extremely communicable and pathogenic viral infection caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), which emerged in Wuhan, China in December 2019 and has spread to almost all the countries in the world. The transmission of the virus is through touching of the nose, eyes, or mouth by a finger that has been contaminated through droplets on a surface when a carrier sneezes or coughs. Since the existing fingerprint devices are predominantly contact based, it implies that they can aid in the transmission of the virus. This paper discusses the application of fingerprint devices in notable places with high rate of COVID-19 infection as well as the threats to fingerprint technologies and the countermeasures. The need to change focus and orientation towards contactless biometric technologies as sure solution to the fear and animosity expressed towards contact-based fingerprint technology is also expatiated.

Digital credential infrastructure: gateways to the future of medicine (Preprint)

2021 ◽  
Author(s):  
James Brogan ◽  
Henry Goodier ◽  
Manreet Nijjar ◽  
Christian Rose
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Information Exchange ◽  
Digital Technologies ◽  
Healthcare Systems ◽  
Critical Moment ◽  
The World ◽  
The Future

UNSTRUCTURED The current credentialing process for physicians struggled to accommodate fluctuating regional demands for providers during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. This hurdle highlighted existing inefficiencies and difficulties facing healthcare systems across the world and led us to explore how credentialing can be improved using digital technologies. We explain how this is a critical moment to make the shift from physical to digital credentials by specifying how a digital credentialing system could simplify onboarding for providers, enable secure expansion of telehealth services, and enhance information exchange.

Tri-primer-enhanced strand exchange amplification combined with rapid lateral flow fluorescent immunoassay to detect SARS-CoV-2

The Analyst ◽  
2021 ◽  
Author(s):  
Linlin Zhuang ◽  
Jiansen Gong ◽  
Ming Ma ◽  
Yongxin Ji ◽  
Peilong Tian ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Lateral Flow ◽  
Strand Exchange ◽  
The Novel ◽  
The World ◽  
Novel Coronavirus

The novel coronavirus disease 2019 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been surging rapidly around the world, which exposes humanity to unprecedented economic, social and...

scholarly journals SARS-CoV-2: Structure, Biology, and Structure-Based Therapeutics Development

2020 ◽  
Vol 10 ◽  
Author(s):  
Mei-Yue Wang ◽  
Rong Zhao ◽  
Li-Juan Gao ◽  
Xue-Fei Gao ◽  
De-Ping Wang ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Protein Structures ◽  
The Novel ◽  
Recognition Mechanism ◽  
Antiviral Compounds ◽  
The World ◽  
Receptor Recognition ◽  
Epidemiological Characteristics ◽  
Therapeutics Development

The pandemic of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been posing great threats to the world in many aspects. Effective therapeutic and preventive approaches including drugs and vaccines are still unavailable although they are in development. Comprehensive understandings on the life logic of SARS-CoV-2 and the interaction of the virus with hosts are fundamentally important in the fight against SARS-CoV-2. In this review, we briefly summarized the current advances in SARS-CoV-2 research, including the epidemic situation and epidemiological characteristics of the caused disease COVID-19. We further discussed the biology of SARS-CoV-2, including the origin, evolution, and receptor recognition mechanism of SARS-CoV-2. And particularly, we introduced the protein structures of SARS-CoV-2 and structure-based therapeutics development including antibodies, antiviral compounds, and vaccines, and indicated the limitations and perspectives of SARS-CoV-2 research. We wish the information provided by this review may be helpful to the global battle against SARS-CoV-2 infection.

scholarly journals Optimization of the CDC Protocol of Molecular Diagnosis of COVID-19 for Timely Diagnosis

Diagnostics ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 333 ◽  
Author(s):  
Chao-Ju Chen ◽  
Li-Ling Hsieh ◽  
Shu-Kai Lin ◽  
Chu-Feng Wang ◽  
Yi-Hui Huang ◽  
...  
Keyword(s):  
Public Health ◽  
Infectious Disease ◽  
Severe Acute Respiratory Syndrome ◽  
Reverse Transcriptase ◽  
Gold Standard ◽  
Health Needs ◽  
The Novel ◽  
Assay Optimization ◽  
The World ◽  
Polymerase Chain

Coronavirus disease 2019 (COVID-19), the current uncontrolled outbreak of infectious disease, has caused significant challenges throughout the world. A reliable rapid diagnostic test for COVID-19 is demanded worldwide. The real-time reverse transcriptase polymerase chain was one of the most quickly established methods in the novel viral pandemic and was considered as the gold standard for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this report, we illustrate our experience of applying a protocol from the Taiwan CDC and achieving assay optimization in the immediate circumstances to meet the urgent medical and public health needs.

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