scholarly journals The Factors Affectıng The Effıcıency Of Contınuous Ambulatory Perıtoneal Dıalysıs In Chıldren

2021 ◽  
Author(s):  
Deniz Ökdemir ◽  
Nilgün Çakar ◽  
İrfan Oğuz Şahin

Objective: Peritoneal dialysis is a complex and variable process. Many factors can affect efficiency of dialysis, and relevant mortality and morbidity rates. Efficient dialysis is important in improving quality of life as well as reducing the morbidity and mortality rates. Dialysis fill volume, intraperitoneal pressure and ultrafiltration (UF) are important variables that determine dialysis efficiency. We aimed to investigate the factors affecting dialysis efficiency and to determine necessities to develop a more effective dialysis program. Methods: Sixteen continuous ambulatory peritoneal dialysis (CAPD) patients between the ages of 7 and 19 years who were followed up in the Pediatric Nephrology Department were included in the study. Patients who had peritonitis, surgical or medical complications in the last 6 months were excluded from the study. Demographic data, duration of dialysis, hemogram, urea, creatinine, albumin, glucose levels, intraperitoneal pressures, peritoneal equilibration test (PET) and Kt/Vurea test results were recorded. Results: Mean Kt /Vurea, dialysis fill volume, UF, intraperitoneal pressure, Hb and serum albumin were found as 2.5±0.93 (1.22-4.64), 1123.4±126.86 (875-1360) ml/m2, 600.1±382.15 (85 -1375) ml, 12.9±2.77 (8.5-19) cm/H2O, 9.0±1.54 (6.3-11.8) gr/dl and 3.6±0.61 (2.45-4.8) gr/dl, respectively. A statistically significant relationship was shown between UF and Kt/Vurea (p=0.04). The mean duration of dialysis was 54±36 months. The majority of the cases had high (37.5%) and medium-high (31.25%) peritoneal permeability. High permeability was found to have a significant relationship with the duration of dialysis (p=0.04). Conclusion: Efficient peritoneal dialysis depends on preserved ultrafiltration. Therefore, the dialysate volume should be calculated according to the intraperitoneal pressure and dialysis should be adjusted according to the permeability properties of the peritoneal membrane.

Author(s):  
Mehtap Çelakıl ◽  
Yasemin Çoban

Abstract Background: Chronic kidney disease (CKD) and end-stage renal disease (ESRD) are among the important causes of mortality and morbidity in childhood. Early diagnosis and treatment of the underlying primary disease may prevent most of CKD patients from progressing to ESRD. There is no study examining chronic kidney diseases and dialysis modalities in Syrian immigrant children. We aimed to retrospectively research the etiologic, sociodemographic, and clinical factors in CKD among Syrian refugee children, and at the same time, to compare the clinical characteristics of patients with ESRD on peritoneal dialysis and hemodialysis. Methods: Our study included a total of 79 pediatric Syrian patients aged from 2-16 years monitored at Hatay State Hospital pediatric nephrology clinic with diagnosis of various stages of CKD and with ESRD. Physical-demographic features and clinical-laboratory information were retrospectively screened. Results: The most common cause of CKD was congenital anomalies of the kidneys and urinary tracts (CAKUT) (37.9%). Other causes were urolitiasis (15.1%), nephrotic syndrome (10.1%), spina bifida (8.8%), hemolytic uremic syndrome (7.5%), and glomerulonephritis (7.5%). Twenty-five patients used hemodialysis due to bad living conditions. Only 2 of the patients with peritoneal dialysis were using automatic peritoneal dialysis (APD), with 5 using continuous ambulatory peritoneal dialysis (CAPD). Long-term complications like left ventricle hypertrophy and retinopathy were significantly higher among hemodialysis patients. There was no difference identified between the groups in terms of hypertension and sex. Conclusion: Progression to ESRD due to preventable reasons is very frequent among CKD patients. For more effective use of peritoneal dialysis in pediatric patients, the responsibility of states must be improved.


1993 ◽  
Vol 13 (2_suppl) ◽  
pp. 242-244 ◽  
Author(s):  
Sophia Spaia ◽  
Fotini Christidou ◽  
Panayotis Pangidis ◽  
Thomas Tsoulkas ◽  
Michalis Pazarloglou ◽  
...  

In order to evaluate the Influence of diabetes mellitus on peritoneal membrane permeability, we studied the peritoneal protein loss In two groups of patients. Group A consisted of 16 patients (9 nondlabetics and 7 diabetics) who were In the first month of treatment on continuous ambulatory peritoneal dialysis (CAPO). Group B consisted of 13 patients (7 nondlabetics and 6 diabetics) who had been on CAPO for approximately 15 months. In both groups we measured the body weight, serum total protein, albumin, and total protein, urea, and glucose In the peritoneal fluid. We did not find any difference In groups A and B between diabetics and nondlabetics as far as the estimated parameters were concerned. Age, body weight, serum biochemistry, and protein and urea content In peritoneal fluid were similar, when group A was compared to group B. Patients of group B hed on average higher protein losses than those who had been on the method for a short period (mean 7.9 g/dL, vs 6.09 g/dL). Six patients were followed for over 15 months and were found to have significantly Increased protein losses (p=0.02). Glucose levels In peritoneal fluid were significantly lower In patients In group B, p<0.05 (mean 51.8 g/dL vs 37.1 g/dL). Peritoneal protein loss does not seem to differ between diabetic and nondiabetic patients with end-stage renal disease treated with CAPO, at any given time of the treatment. We observed an Increase In protein loss In some patients and a tendency to Increase the protein loss In others. This, along with the fall In glucose levels, might reflect progressive alterations In structure and permeability of the elements Involved In peritoneal transport, and It should receive further evaluation.


2017 ◽  
Vol 25 (1) ◽  
pp. 32-38
Author(s):  
Shireen Afroz ◽  
Tahmina Ferdaus ◽  
Rokeya Khanam ◽  
Maliha Alam Simi ◽  
Sanjida Sharmim ◽  
...  

The lifespan and outcome of End Stage Kidney Failure (ESKF) children have dramatically improved since the development of continuous ambulatory peritoneal dialysis (CAPD), it offers several advantages over hemodialysis. This study was done to evaluate the efficacy, outcome and to find out the complication profile of CAPD. This prospective longitudinal study was carried out in the department of Pediatric Nephrology, Dhaka Medical College Hospital (DMCH), Bangladesh, over a period of 3 year. A total of 8 children with ESKF were included. (Age 5-14 year, M:F=1:1), All underwent CAPD. Average duration of CAPD 40.6 months with a total of 185 patient months of CAPD. The rate of complications was recorded. Common complications being observed were peritonitis 1 episode per 13.9 patient months, catheter obstruction by omental capture was in 4. Catheter tip dislocation was found in 3 children and all needed laparotomy and omentectomy. Satisfactory level of improvement of mean weight, mean serum albumin and declining of serum creatinine has been found after CAPD in all 8 study children. At the end of the study, 3 out of 8 are still on CAPD, 2 transferred to haemodialysis and 3 expired due to uncontrolled hypertension with congestive heart failure and sepsis. So, CAPD is an effective modality of renal replacement therapy for children. Early detection of complications and prompt therapy is essential for a favourable outcome. Placement of catheter by surgical method with elective omentectomy will reduce catheter related complications.J Dhaka Medical College, Vol. 25, No.1, April, 2016, Page 32-38


1984 ◽  
Vol 4 (1) ◽  
pp. 14-19 ◽  

In 20 participating centers in Canada, France and the USA, 210 patients on continuous ambulatory peritoneal dialysis for one to 66 months underwent drainage measurements with a hypertonic (3.86 to 4.5 gm % dextrose), 2L, four-hour-dwell exchange. Patients had used lactate solutions only (n = 73), acetate solutions only (n = 21), or acetate before a change to lactate (n = 16). Mean net ultrafiltration (± SEM) (UF, ml) values were 701 ± 22, 489 ± 61, and 390 ± 56 respectively; mean dialysate glucose concentrations (mg/dl) were 1053 ± 23, 722 ± 107, and 701 ± 24. Mean values in groups exposed to acetate were significantly (p < 0.01) below those in the lactate-only group. There was no significant correlation of UF with the peritonitis rate; in the lactate-only group, there was no significant correlation between UF and time on CAPD. In summary, the chronic use of acetate solutions appeared to be associated with more rapid decreases in dialysate glucose and low UF Slingeneyer et al reported that 10 and 30% of patients treated with continuous ambulatory peritoneal dialysis (CAPD) at their center in France lose ultrafiltration capacity at one and two years respectively (I). Eventually 24% of patients with decreasing ultrafiltration had to be transferred to hemodialysis.


BMJ ◽  
1984 ◽  
Vol 289 (6457) ◽  
pp. 1485-1486 ◽  
Author(s):  
T H Goodship ◽  
A Heaton ◽  
R S Rodger ◽  
M K Ward ◽  
R Wilkinson ◽  
...  

2010 ◽  
Vol 1 (2) ◽  
Author(s):  
Supono .

Faktor-Faktor Yang Berkontribusi Terjadinya Peritonitis pada Pasien Continuous Ambulatory Peritoneal Dialysis (CAPD) di Rumah Sakit Umum Dr Saiful Anwar MalangContributing Factors For Peritonitis Incidence On Continuous Ambulatory Peritoneal Dialysis (CAPD) Patients In Dr Saiful Anwar Malang HospitalSuponoProgram Studi Keperawatan Lawang Poltekkes Kemenkes MalangJl. A. Yani No 1 Lawang 65218e-mail: [email protected] ambulatory peritoneal dialysis (CAPD) adalah dialisis yang dilakukan melalui rongga peritonium (rongga perut) dengan selaput atau membran perutonium berfungsi sebagai filter. Tindakan CAPD dilakukan dengan insisi kecil pada dinding abdomen untuk pemasangan kateter, risiko komplikasi yang sering terjadi adalah infeksi pada peritonium (peritonitis). Tujuan penelitian untuk mengetahui hubungan faktor-faktor yang berkontribusi terjadinya peritonitis pada pasien CAPD di Rumah Sakit Umum Dr Saiful Anwar Malang Jawa Timur. Jenis penelitian deskkriptif korelasi dengan rancangan cross sectional study. Jumlah sampel penelitian 22 pasien peritonitis CAPD dan 13 perawat dialisis, dengan tehnik pengambilan sample menggunakan total sampling. Hasil penelitian menunjukan ada hubungan yang signifikan antara status nutrisi (p = 0,032), kemampuan perawatan (p = 0,024) dengan kejadian peritonitis pada pasien CAPD. Tidak ada hubungan yang signifikan antara umur (p = 0,702), jenis kelamin (p = 0,669), tingkat pendidikan (p = 0,771), penghasilan (p = 1,000), personal hygine (p = 0,387), support system (p = 1,000), fasilitas perawatan (p = 0,088), standar struktur (p = 0,203), standar proses (p = 0,559) dengan kejadian peritonitis pada pasien CAPD. Rekomendasi untuk perawat meningkatkan kunjungan rumah untuk memberikan pendidikan kesehatan tentang perawatan dialisis dan pengeloaan nutrisi seimbang. Saran untuk pasien diharapkan mengikuti prosedur standar perawatan yang telah diajarkan.Kata kunci: peritonitis, CAPD, perawat, pasien CAPDABSTRACTContinuous ambulatory peritoneal dialysis (CAPD) is a dialysis conducted through peritonium with perutonium membrane functions as a filter. CAPD procedure is conducted by making small incision on abdomen wall to insert catheter. Complication risk which often happens is the infection on peritoneum (peritonitis). The purpose of this research was to find out the relationship between contributing factors for peritonitis incidence on CAPD patients in Dr Saiful Anwar hospital in Malang, East Java. The type of this research was correlation descriptive cross sectional study design. The number of the sample were 22 peritonitis CAPD patients and 13 dialysis patients, using total sampling technique. The result showed that there was significant relationship between nutrition status (p = 0,032), treatment capability (p = 0,024) with peritonitis incidence on CAPD patients. There was no significant relationship between age (p = 0,702), sex or gender (p = 0,669), level of education (p = 0,771), income (p = 1,000), personal hygiene (p = 0,387), support system (p = 1,000), treatment facilities (p = 0,088), structure standard (p = 0,203), process standard (p = 0,559) with peritonitis incidence on CAPD patients. It is recommended to nurses to increase home visit to give health education about dialysis treatment and balanced nutrition management. It is also suggested to the patients to follow procedure for standard treatment which had been taught to them.Keywords: peritonitis, CAPD, nurse, CAPD patient


2021 ◽  
Vol 9 (B) ◽  
pp. 373-377
Author(s):  
Yuswinda Kusumawardhani ◽  
Krisna Yetti ◽  
I Made Kariasa

BACKGROUND: Sexual dysfunction is a complication of terminal kidney failure. The problem of fulfilling sexual needs of men undergoing Continuous Ambulatory Peritoneal Dialysis (CAPD) is influenced by many factors. AIM: This study aims to find out the most dominant factor affecting the sexual dysfunction of men who undergo CAPD. METHODS: The design of this study was cross-sectional analysis with a sample of 70 men CAPD patients using a purposive sampling technique from February to May 2020. Data collection was carried out offline and online by filling in the questionnaire sheets for respondent characteristics, International Index of Erectile Function, and looking at laboratory result. RESULTS: The results showed there was a correlation between age (p=0.0024), plasma urea (p=0.018), and albumin (p=0.001) with sexual dysfunction in male patients using CAPD. There was no significant correlation between length of time undergoing CAPD (p=0.678), fasting glucose (0.051), triglycerides (p=0.536), and cholesterol (p=0.183) with sexual dysfunction in male patients who undergo CAPD. The most dominant factor affecting is albumin, where patients who have albumin levels < 3.5 g/dL are at risk of experiencing sexual dysfunction 9.3 times greater than patients with albumin levels 3.5-5 g/dL after being controlled by age variables. CONCLUSION: The recommendation of this study is protein intake of 1.2-1.5 g/kg body weight with at least 60% of protein with high biological value and evaluation of the ability of care and replacement of CAPD at home.


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